GB1157275A - A Method for the Production of 5'-Ribonucleotide - Google Patents
A Method for the Production of 5'-RibonucleotideInfo
- Publication number
- GB1157275A GB1157275A GB33391/66A GB3339166A GB1157275A GB 1157275 A GB1157275 A GB 1157275A GB 33391/66 A GB33391/66 A GB 33391/66A GB 3339166 A GB3339166 A GB 3339166A GB 1157275 A GB1157275 A GB 1157275A
- Authority
- GB
- United Kingdom
- Prior art keywords
- pcl
- ribonucleoside
- phosphorylating
- alcoholysed
- july
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002336 ribonucleotide Substances 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 4
- XHXFXVLFKHQFAL-UHFFFAOYSA-N phosphoryl trichloride Chemical compound ClP(Cl)(Cl)=O XHXFXVLFKHQFAL-UHFFFAOYSA-N 0.000 abstract 4
- 230000000865 phosphorylative effect Effects 0.000 abstract 4
- NYHBQMYGNKIUIF-UUOKFMHZSA-N Guanosine Chemical compound C1=NC=2C(=O)NC(N)=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O NYHBQMYGNKIUIF-UUOKFMHZSA-N 0.000 abstract 3
- 239000002342 ribonucleoside Substances 0.000 abstract 3
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 125000001931 aliphatic group Chemical group 0.000 abstract 2
- FDGQSTZJBFJUBT-UHFFFAOYSA-N hypoxanthine Chemical compound O=C1NC=NC2=C1NC=N2 FDGQSTZJBFJUBT-UHFFFAOYSA-N 0.000 abstract 2
- -1 nitrile compound Chemical class 0.000 abstract 2
- RWQNBRDOKXIBIV-UHFFFAOYSA-N thymine Chemical compound CC1=CNC(=O)NC1=O RWQNBRDOKXIBIV-UHFFFAOYSA-N 0.000 abstract 2
- KPZGRMZPZLOPBS-UHFFFAOYSA-N 1,3-dichloro-2,2-bis(chloromethyl)propane Chemical compound ClCC(CCl)(CCl)CCl KPZGRMZPZLOPBS-UHFFFAOYSA-N 0.000 abstract 1
- UGQMRVRMYYASKQ-UHFFFAOYSA-N Hypoxanthine nucleoside Natural products OC1C(O)C(CO)OC1N1C(NC=NC2=O)=C2N=C1 UGQMRVRMYYASKQ-UHFFFAOYSA-N 0.000 abstract 1
- JLEBZPBDRKPWTD-TURQNECASA-O N-ribosylnicotinamide Chemical compound NC(=O)C1=CC=C[N+]([C@H]2[C@@H]([C@H](O)[C@@H](CO)O2)O)=C1 JLEBZPBDRKPWTD-TURQNECASA-O 0.000 abstract 1
- OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine group Chemical group [C@@H]1([C@H](O)[C@H](O)[C@@H](CO)O1)N1C=NC=2C(N)=NC=NC12 OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 238000001816 cooling Methods 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 150000002825 nitriles Chemical class 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 229940113082 thymine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
- C07H1/02—Phosphorylation
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4573165 | 1965-07-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1157275A true GB1157275A (en) | 1969-07-02 |
Family
ID=12727451
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB33391/66A Expired GB1157275A (en) | 1965-07-27 | 1966-07-25 | A Method for the Production of 5'-Ribonucleotide |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US3407190A (https=) |
| BE (1) | BE684554A (https=) |
| FR (1) | FR1487712A (https=) |
| GB (1) | GB1157275A (https=) |
| NL (1) | NL139315B (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3466273A (en) * | 1966-12-16 | 1969-09-09 | Asahi Chemical Ind | Process for producing nucleotide by a selective phosphorylation |
| US4152209A (en) * | 1974-03-29 | 1979-05-01 | Sanraku-Ocean Co., Ltd. | Nucleotide pyrophosphotransferase and method of preparation |
| ZA821534B (en) * | 1981-03-10 | 1984-04-25 | Bioresearch Inc | Rapid solid phase synthesis of olignucleotides using phosphorus oxychloride activation |
| JPS5843993A (ja) * | 1981-09-09 | 1983-03-14 | Yamasa Shoyu Co Ltd | 1−β−D−アラビノフラノシル−(E)−5−(2−ハロゲノビニル)ウラシル−5′−りん酸およびその製造法 |
| US6458778B1 (en) | 1997-04-07 | 2002-10-01 | Wyeth | Estradienes |
| US6958324B2 (en) * | 1998-12-02 | 2005-10-25 | Inotek Pharmaceuticals Corporation | Inosine compounds and their use for treating or preventing an inflamation or a reperfusion disease |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2970139A (en) * | 1958-05-20 | 1961-01-31 | Duschinsky Robert | 5-fluorouracil nucleotides and preparation thereof |
| US3201388A (en) * | 1962-04-20 | 1965-08-17 | Ajinomoto Kk | Method of preparing 5'-ribonucleotides |
| US3201389A (en) * | 1962-09-24 | 1965-08-17 | Kyowa Hakko Kogyo Kk | Method for preparing ribonucleoside-5'-phosphates or their salts from ribonucleosides |
| NL126431C (https=) * | 1963-02-21 | 1900-01-01 | ||
| US3282920A (en) * | 1963-03-19 | 1966-11-01 | Asahi Chemical Ind | Method for producing 5'-nucleotides |
-
1966
- 1966-07-25 BE BE684554D patent/BE684554A/xx unknown
- 1966-07-25 GB GB33391/66A patent/GB1157275A/en not_active Expired
- 1966-07-25 FR FR70764A patent/FR1487712A/fr not_active Expired
- 1966-07-26 US US567844A patent/US3407190A/en not_active Expired - Lifetime
- 1966-07-27 NL NL666610578A patent/NL139315B/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NL139315B (nl) | 1973-07-16 |
| FR1487712A (fr) | 1967-07-07 |
| US3407190A (en) | 1968-10-22 |
| NL6610578A (https=) | 1967-01-30 |
| BE684554A (https=) | 1967-01-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PE | Patent expired |