GB1153109A - Stabilised Co-Enzyme Test Compositions - Google Patents

Stabilised Co-Enzyme Test Compositions

Info

Publication number
GB1153109A
GB1153109A GB4379467A GB4379467A GB1153109A GB 1153109 A GB1153109 A GB 1153109A GB 4379467 A GB4379467 A GB 4379467A GB 4379467 A GB4379467 A GB 4379467A GB 1153109 A GB1153109 A GB 1153109A
Authority
GB
United Kingdom
Prior art keywords
dehydrogenase
cysteine
compositions
test compositions
dinucleotide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4379467A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of GB1153109A publication Critical patent/GB1153109A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/008—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions for determining co-enzymes or co-factors, e.g. NAD, ATP
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/54—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Emergency Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Steering-Linkage Mechanisms And Four-Wheel Steering (AREA)

Abstract

1,153,109. Stabilized coenzyme test compositions. BOEHRINGER MANNHEIM G.m.b.H. 26 Sept., 1967 [12 Dec., 1966], No. 43794/67. Heading B1X. A stabilized coenzyme test composition comprises reduced nicotinamide - adenine - dinucleotide (diphosphopyridine - nucleotide) and/or reduced nicotinamide - adenine - dinucleotide - phosphate (triphosphopyridinenucleotide) together with at least one SH- group containing compound, for example glutathione, cysteine, cysteine carbamide, acetyl cysteine, homocysteine, thiolactone, N- acetyl-homocysteine thiolactone, thioglycollates, dithiothreitol. Examples relate to compositions for the determination of glutamatepyruvate transaminase, glutamate-oxalacetate transaminase, lactate dehydrogenase, aldolase, pyruvate kinase, sorbitol dehydrogenase, malate dehydrogenase adenosine-5<SP>1</SP>-triphosphate, α-hydroxy-butylate-dehydrogenase, creatine phosphokinase, glutamate dehydrogenase, glutathione reductase, glucose. The test compositions are prepared 'by dissolving all components in water, adjusting the pH to 7.6 with sodium hydroxide solution and lyophilising.
GB4379467A 1966-12-12 1967-09-26 Stabilised Co-Enzyme Test Compositions Expired GB1153109A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEB0090269 1966-12-12

Publications (1)

Publication Number Publication Date
GB1153109A true GB1153109A (en) 1969-05-21

Family

ID=6985205

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4379467A Expired GB1153109A (en) 1966-12-12 1967-09-26 Stabilised Co-Enzyme Test Compositions

Country Status (11)

Country Link
JP (1) JPS5018399B1 (en)
AT (1) AT277937B (en)
BE (1) BE707864A (en)
CH (1) CH481380A (en)
DE (1) DE1598157C3 (en)
DK (1) DK133287C (en)
ES (1) ES346631A1 (en)
FI (1) FI48511C (en)
GB (1) GB1153109A (en)
NL (1) NL6714582A (en)
NO (1) NO122347B (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3791929A (en) * 1968-09-08 1974-02-12 Searle & Co Phosphatase assay using lyophilized aryl phosphate monesters
US3819487A (en) * 1970-10-13 1974-06-25 Boehringer Mannheim Gmbh Stable nadh compositions
US3819488A (en) * 1971-07-20 1974-06-25 Technicon Instr Diagnostic compositions for glutamic oxalic transaminase (got) and glutamic pyruvic transaminase (gpt) determinations
EP0052780A1 (en) * 1980-11-26 1982-06-02 Roche Diagnostics GmbH Stabilized enzyme preparation
EP0463755A1 (en) * 1990-06-27 1992-01-02 INSTRUMENTATION LABORATORY S.p.A. Stable aqueous NADH reagent and kit

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4124286A1 (en) * 1991-07-22 1993-01-28 Boehringer Mannheim Gmbh METHOD FOR STABILIZING PROTEINS IN OPTICAL TESTS

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3791929A (en) * 1968-09-08 1974-02-12 Searle & Co Phosphatase assay using lyophilized aryl phosphate monesters
US3819487A (en) * 1970-10-13 1974-06-25 Boehringer Mannheim Gmbh Stable nadh compositions
US3819488A (en) * 1971-07-20 1974-06-25 Technicon Instr Diagnostic compositions for glutamic oxalic transaminase (got) and glutamic pyruvic transaminase (gpt) determinations
EP0052780A1 (en) * 1980-11-26 1982-06-02 Roche Diagnostics GmbH Stabilized enzyme preparation
EP0463755A1 (en) * 1990-06-27 1992-01-02 INSTRUMENTATION LABORATORY S.p.A. Stable aqueous NADH reagent and kit
US5278044A (en) * 1990-06-27 1994-01-11 Instrumentation Laboratory, S.P.A. Stable aqueous NADH reagent and kit

Also Published As

Publication number Publication date
DE1598157C3 (en) 1973-11-22
FI48511C (en) 1974-10-10
AT277937B (en) 1970-01-12
DE1598157A1 (en) 1972-03-23
JPS5018399B1 (en) 1975-06-28
DE1598157B2 (en) 1973-04-19
DK133287C (en) 1976-10-18
NL6714582A (en) 1968-06-13
FI48511B (en) 1974-07-01
NO122347B (en) 1971-06-14
CH481380A (en) 1969-11-15
BE707864A (en) 1968-06-12
DK133287B (en) 1976-04-20
ES346631A1 (en) 1969-01-01

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Legal Events

Date Code Title Description
PS Patent sealed
PE20 Patent expired after termination of 20 years