GB1136194A - Radioactive package and container therefor - Google Patents

Radioactive package and container therefor

Info

Publication number
GB1136194A
GB1136194A GB15334/67A GB1533467A GB1136194A GB 1136194 A GB1136194 A GB 1136194A GB 15334/67 A GB15334/67 A GB 15334/67A GB 1533467 A GB1533467 A GB 1533467A GB 1136194 A GB1136194 A GB 1136194A
Authority
GB
United Kingdom
Prior art keywords
column
lead
stopper
radioactivity
shielding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB15334/67A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of GB1136194A publication Critical patent/GB1136194A/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
    • G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
    • G21G1/0005—Isotope delivery systems
    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21F—PROTECTION AGAINST X-RADIATION, GAMMA RADIATION, CORPUSCULAR RADIATION OR PARTICLE BOMBARDMENT; TREATING RADIOACTIVELY CONTAMINATED MATERIAL; DECONTAMINATION ARRANGEMENTS THEREFOR
    • G21F5/00—Transportable or portable shielded containers
    • G21F5/015—Transportable or portable shielded containers for storing radioactive sources, e.g. source carriers for irradiation units; Radioisotope containers
    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
    • G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
    • G21G1/001—Recovery of specific isotopes from irradiated targets
    • G21G2001/0042—Technetium

Landscapes

  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

1,136,194. Shielded containers for radioactive material. E. R. SQUIBB & SONS Inc. 4 April, 1967 [6 April, 1966], No. 15334/67. Heading B4Q. [Also in Division G6] A sterile column 3 containing radioactivity for medical use is housed in an opening 4 in a shielding container I closed by a shielding lid 2. The shielding material may be lead, a lead-antimony alloy iron, or a lead salt such as lead carbonate or lead sulphide embedded in plastic. Access to the column 3 is obtained by removing shielding plugs 8, 9 situated, respectively, in the base of the container 1 and in the lid 2. The column 3 is of glass or transparent plastic material and is closed by rubber stoppers 15, 16 pierceable by a hypodermic needle. A breather tube 19 connects the space in the lower end of the column to atmosphere and above the tube is a funnellike partition 22 supporting a perforated disc 24 of fritted glass. A filter pad 25 resting on the disc 24 supports a granulation 26 of a radioactivity - containing alumina. In use, radioactivity is introduced into the granulation 26 by piercing the stopper 15 with a hollow needle connected to a reservoir containing an aqueous solution of radioactive Mo<SP>99</SP> ammonium molybdate. Excess molybdenum and water are removed through a drainage needle piercing the stopper 16. To extract the radioactivity the column is eluted by injecting a non-pyrogenic isotonic saline solution through the stopper 15 by means of a hypodermic syringe, the eluate containing the radioactive material, i.e. the 99m isotope of technetium, collecting at the bottom of the column. When the eluate is to be used, it is removed by piercing the stopper 16 with a hypodermic needle. In a modification (Figs. 4, 5, not shown), there is no empty space at the lower end of the column and the eluate is removed whilst the column is being eluted.
GB15334/67A 1966-04-06 1967-04-04 Radioactive package and container therefor Expired GB1136194A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US540689A US3369121A (en) 1966-04-06 1966-04-06 Radioactive package and container therefor

Publications (1)

Publication Number Publication Date
GB1136194A true GB1136194A (en) 1968-12-11

Family

ID=24156537

Family Applications (1)

Application Number Title Priority Date Filing Date
GB15334/67A Expired GB1136194A (en) 1966-04-06 1967-04-04 Radioactive package and container therefor

Country Status (5)

Country Link
US (1) US3369121A (en)
BE (1) BE714824A (en)
DE (1) DE1614486C2 (en)
GB (1) GB1136194A (en)
NL (1) NL160419C (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0383153A1 (en) * 1989-02-11 1990-08-22 Kernforschungszentrum Karlsruhe Gmbh Device for containers with radioactive waste for the reduction of internal pressure caused by the formation of hydrogen
WO2006135987A1 (en) * 2005-06-24 2006-12-28 Australian Nuclear Science And Technology Organisation Method and apparatus for isolating material from its processing environment
AU2003209692B2 (en) * 2002-02-11 2008-06-12 Alfasigma S.P.A. Container for vial of radiopharmaceutical and set for its infusion in a patient or for its transfer elsewhere

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3446965A (en) * 1966-08-10 1969-05-27 Mallinckrodt Chemical Works Generation and containerization of radioisotopes
US3576998A (en) * 1966-11-16 1971-05-04 Nen Picker Radiopharmaceutical Self-contained, closed system and method for generating and collecting a short-lived daughter radionuclide from a long-lived parent radionuclide
US3440423A (en) * 1967-04-10 1969-04-22 Squibb & Sons Inc Process for preparing sterile radioactive material of the parentdaughter type
US3535085A (en) * 1967-08-07 1970-10-20 Mallinckrodt Chemical Works Closed system generation and containerization of radioisotopes
FR1563936A (en) * 1968-02-28 1969-04-18
US3783291A (en) * 1968-11-25 1974-01-01 Squibb & Sons Inc Sterile generator housing and support
NL7008953A (en) * 1969-06-20 1970-12-22
US3766388A (en) * 1971-06-04 1973-10-16 Gen Nuclear Inc Radioactive tracer method and apparatus for boreholes
US3774035A (en) * 1971-07-12 1973-11-20 New England Nuclear Corp Method and system for generating and collecting a radionuclide eluate
US3754141A (en) * 1972-07-12 1973-08-21 Atomic Energy Commission Shipping and storage container for high power density radioactive materials
US3801818A (en) * 1972-10-24 1974-04-02 Squibb & Sons Inc Radioactive generator with permeable closure
US3814941A (en) * 1972-10-24 1974-06-04 Squibb & Sons Inc Loading syringe for use with radioactive solutions and other non-sterile solutions
US3957033A (en) * 1973-08-15 1976-05-18 General Electric Company Ventilation study system
US3926176A (en) * 1973-08-15 1975-12-16 Gen Electric Radioactive gas-containing polymeric capsule
JPS4984600U (en) * 1973-10-09 1974-07-22
US4160910A (en) * 1977-06-20 1979-07-10 Union Carbide Corporation Rechargeable 99MO/99MTC generator system
NL7902342A (en) * 1979-03-26 1980-09-30 Byk Mallinckrodt Cil Bv ISOTOPE GENERATOR.
DE2915376C2 (en) * 1979-04-14 1984-02-02 Transnuklear Gmbh, 6450 Hanau Container combination for the transport and storage of spent fuel elements from nuclear reactors
US4597951A (en) 1984-08-16 1986-07-01 E. R. Squibb & Sons, Inc. Strontium-82/rubidium-82 generator
DE3531355A1 (en) * 1985-09-03 1987-03-12 Hoechst Ag TECHNETIUM 99M GENERATOR, ITS PRODUCTION AND USE
US5071965A (en) * 1988-07-19 1991-12-10 Mallinckrodt Medical, Inc. Novel tc-99m complexes
CA2034042C (en) 1990-01-18 1999-08-17 Adrian D. Nunn Boronic acid adducts of rhenium dioxime and technetium-99m dioxime complexes containing a biochemically active group
US5109160A (en) * 1990-10-12 1992-04-28 E. I. Du Pont De Nemours And Company Sterilizable radionuclide generator and method for sterilizing the same
US5808091A (en) * 1991-10-29 1998-09-15 Bracco International B.V. Rhenium and technetium complexes containing a hypoxia localizing moiety
US5608110A (en) * 1993-06-15 1997-03-04 Bracco International B.V. Heteroatom-bearing ligands and metal complexes thereof
DE69501981T2 (en) 1994-01-12 1998-12-10 Bracco Int Bv LIGANDS AND THEIR METAL COMPLEXES
US6337052B1 (en) * 1999-11-15 2002-01-08 The Penn State Research Foundation Insulated specimen container
EP2279757A3 (en) 2000-06-02 2011-08-03 Bracco Suisse SA Compounds for targeting endothelial cells
GB2386743B (en) * 2002-04-11 2004-02-11 Amersham Plc Radioisotope generator
US6989543B2 (en) 2003-08-15 2006-01-24 C.R. Bard, Inc. Radiation shielding container for radioactive sources
US7186994B1 (en) * 2003-09-17 2007-03-06 The S.M. Stoller Corporation Container for transport of hazardous materials
US7199375B2 (en) * 2004-10-12 2007-04-03 Bard Brachytherapy, Inc. Radiation shielding container that encloses a vial of one or more radioactive seeds
EP2431979A1 (en) * 2005-07-27 2012-03-21 Mallinckrodt LLC Radiation-shielding assembly
EP3101659B1 (en) * 2006-10-06 2017-07-26 Mallinckrodt Nuclear Medicine LLC Self-aligning radioisotope elution system
US9153350B2 (en) 2011-01-19 2015-10-06 Mallinckrodt Llc Protective shroud for nuclear pharmacy generators
US8866104B2 (en) 2011-01-19 2014-10-21 Mallinckrodt Llc Radioisotope elution system
US8809804B2 (en) * 2011-01-19 2014-08-19 Mallinckrodt Llc Holder and tool for radioisotope elution system
US9233776B2 (en) 2012-06-07 2016-01-12 Bayer Healthcare Llc Molecular imaging vial transport container and fluid injection system interface
US9327886B2 (en) * 2013-03-13 2016-05-03 Bayer Healthcare Llc Vial container with collar cap
US9757306B2 (en) 2013-03-13 2017-09-12 Bayer Healthcare Llc Vial container with collar cap
WO2015066335A1 (en) * 2013-10-30 2015-05-07 NorthStar Medical Radioisotopes LLC Parent radionuclide container
PL3453032T3 (en) 2016-05-04 2022-11-28 Curium Us Llc Systems and methods for sterilizing sealed radionuclide generator column assemblies
CN109915129B (en) * 2019-04-30 2024-06-18 广东太微加速器有限公司 Neutron exploration equipment for petroleum drilling

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2682872A (en) * 1950-06-29 1954-07-06 John O Bower Absorbable wound pad
US2968721A (en) * 1954-09-27 1961-01-17 Tracerlab Inc Methods of flow rate measurement
US2973758A (en) * 1956-12-27 1961-03-07 Invenex Pharmaceuticals Apparatus for manufacturing parenteral solutions

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0383153A1 (en) * 1989-02-11 1990-08-22 Kernforschungszentrum Karlsruhe Gmbh Device for containers with radioactive waste for the reduction of internal pressure caused by the formation of hydrogen
AU2003209692B2 (en) * 2002-02-11 2008-06-12 Alfasigma S.P.A. Container for vial of radiopharmaceutical and set for its infusion in a patient or for its transfer elsewhere
US7842023B2 (en) 2002-02-11 2010-11-30 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Container for vial of radiopharmaceutical and set for its infusion in a patient or for its transfer elsewhere
US8292869B2 (en) 2002-02-11 2012-10-23 Sigma-Tau Industrie Farmaceutiche Riunite Spa Container for vial of radiopharmaceutical and set for its infusion in a patient or for its transfer elsewhere
WO2006135987A1 (en) * 2005-06-24 2006-12-28 Australian Nuclear Science And Technology Organisation Method and apparatus for isolating material from its processing environment
US8662338B2 (en) 2005-06-24 2014-03-04 Australian Nuclear Science And Technology Organisation Container for receiving a substance including nuclear material

Also Published As

Publication number Publication date
DE1614486C2 (en) 1975-07-10
BE714824A (en) 1968-09-30
DE1614486B1 (en) 1970-09-03
NL6704921A (en) 1967-10-09
NL160419C (en) 1979-10-15
US3369121A (en) 1968-02-13

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