GB1134237A - Penicillins - Google Patents
PenicillinsInfo
- Publication number
- GB1134237A GB1134237A GB3119766A GB3119766A GB1134237A GB 1134237 A GB1134237 A GB 1134237A GB 3119766 A GB3119766 A GB 3119766A GB 3119766 A GB3119766 A GB 3119766A GB 1134237 A GB1134237 A GB 1134237A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- penicillins
- group
- phenylsulphonamido
- penicillanate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1,134,237. Penicillins. BEECHAM GROUP Ltd. 11 July, 1967 [12 July, 1966], No. 31197/66. Heading C2A. The invention comprises α-phenylsulphonamido penicillins of Formula (I) and non-toxic salts thereof, wherein R is an alkyl, aryl or heterocyclic group, any of which may be substituted with other groups; Z is H, Y is H and X is carboxy; or X is H and Z and Y together form a carbonyl group linking the phenyl group with the amino group. Typical compounds are sodium 6-[D - α - saccharimidophenyl acetamido] penicillanate, disodium 6- [D - α - (p - carboxyphenylsulphonamido) phenyl acetamido] penicillanate and disodium 6 - [α - (m - carboxy phenylsulphonamido)- α - 2- thienyl acetamido] penicillanate. Penicillins of Formula (I) wherein Z is H, Y is H and X is carboxy are prepared by reacting an α-amino penicillin of Formula (III) wherein R has the above meaning, with a sulphonyl chloride of Formula (IV) Penicillins of Formula (I) wherein X is H and Z and Y together represent a carbonyl group linking the phenyl ring with the amino group, are prepared by reacting the α-aminopenicillin of Formula (III) with an N-(alkoxy carbonyl) amide of Formula (V) wherein R<SP>1</SP> is C 1-5 alkyl. Alternatively these compounds may be prepared by acylating 6- aminopenicillanic acid or a salt thereof, with a reactive derivative of an α-phenylsulphonamido carboxylic acid of Formula (II) wherein R has the above meaning. The penicillins have antibacterial properties and may be used as nutritional supplements in animal feeds.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB3119766A GB1134237A (en) | 1966-07-12 | 1966-07-12 | Penicillins |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB3119766A GB1134237A (en) | 1966-07-12 | 1966-07-12 | Penicillins |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1134237A true GB1134237A (en) | 1968-11-20 |
Family
ID=10319454
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB3119766A Expired GB1134237A (en) | 1966-07-12 | 1966-07-12 | Penicillins |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB1134237A (en) |
-
1966
- 1966-07-12 GB GB3119766A patent/GB1134237A/en not_active Expired
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES368248A1 (en) | New penicillins | |
GB1429539A (en) | Derivatives of penam-3-carboxylic acid and cephem-4-carboxylic acid and processes for their manufacture | |
GB1336318A (en) | Derivatives of 7-aminocephalosporanic acid | |
GB1134237A (en) | Penicillins | |
GB1067965A (en) | Penicillins, esters, amides and salts thereof | |
GB1377661A (en) | Oxofuryl ester derivatives of penicillin and cephalosporin | |
GB1293590A (en) | New penicillanic acid derivatives | |
GB1053818A (en) | ||
GB1061335A (en) | Penicillins | |
GB1250611A (en) | ||
GB1134682A (en) | Improvements in or relating to derivatives of 6-aminopenicillanic acid | |
GB1436977A (en) | 7-alkylthioacetamido cephaosporins | |
GB1040166A (en) | Penicillins | |
GB1081093A (en) | Improvements in or relating to 6-[d(-)-alpha-(amino-phenylacetamido)]-penicillanic acid derivatives | |
GB894460A (en) | Improvements in or relating to penicillins | |
GB1162247A (en) | Cephalosporanic Acid Derivatives and a Process for the Preparation thereof | |
GB1184665A (en) | Penicillins | |
GB1153186A (en) | Penicillanic Acid Derivatives | |
GB1166668A (en) | Penicillins and a process for the preparation thereof | |
GB1180745A (en) | Penicillins | |
GB1224619A (en) | DERIVATIVES OF alpha-AMINOPENICILLINS | |
GB1051675A (en) | ||
GB1292603A (en) | Improvements relating to penicillins | |
GB1398564A (en) | 1-amino substituted-1-cycloalkane derivatives of 6-amino penicillanic acid | |
GB1347979A (en) | Penicillins |