GB1132264A - Process for purifying synthetically prepared peptides - Google Patents
Process for purifying synthetically prepared peptidesInfo
- Publication number
- GB1132264A GB1132264A GB3106/66A GB310666A GB1132264A GB 1132264 A GB1132264 A GB 1132264A GB 3106/66 A GB3106/66 A GB 3106/66A GB 310666 A GB310666 A GB 310666A GB 1132264 A GB1132264 A GB 1132264A
- Authority
- GB
- United Kingdom
- Prior art keywords
- synthetically prepared
- jan
- tert
- amino acids
- oac
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 6
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 2
- 229920002134 Carboxymethyl cellulose Polymers 0.000 abstract 1
- 102400000739 Corticotropin Human genes 0.000 abstract 1
- 101800000414 Corticotropin Proteins 0.000 abstract 1
- 239000000055 Corticotropin-Releasing Hormone Substances 0.000 abstract 1
- 125000000539 amino acid group Chemical group 0.000 abstract 1
- 239000001768 carboxy methyl cellulose Substances 0.000 abstract 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 abstract 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 abstract 1
- 229940105329 carboxymethylcellulose Drugs 0.000 abstract 1
- IDLFZVILOHSSID-OVLDLUHVSA-N corticotropin Chemical compound C([C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)NC(=O)[C@@H](N)CO)C1=CC=C(O)C=C1 IDLFZVILOHSSID-OVLDLUHVSA-N 0.000 abstract 1
- 229960000258 corticotropin Drugs 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000000896 monocarboxylic acid group Chemical group 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 230000001376 precipitating effect Effects 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/695—Corticotropin [ACTH]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Detergent Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEF0045044 | 1965-01-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1132264A true GB1132264A (en) | 1968-10-30 |
Family
ID=7100315
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3106/66A Expired GB1132264A (en) | 1965-01-23 | 1966-01-24 | Process for purifying synthetically prepared peptides |
Country Status (8)
| Country | Link |
|---|---|
| AT (1) | AT282080B (enrdf_load_stackoverflow) |
| BE (1) | BE675499A (enrdf_load_stackoverflow) |
| CH (1) | CH456626A (enrdf_load_stackoverflow) |
| DE (1) | DE1493692A1 (enrdf_load_stackoverflow) |
| FR (1) | FR1481080A (enrdf_load_stackoverflow) |
| GB (1) | GB1132264A (enrdf_load_stackoverflow) |
| NL (1) | NL6600574A (enrdf_load_stackoverflow) |
| SE (1) | SE319189B (enrdf_load_stackoverflow) |
-
1965
- 1965-01-23 DE DE19651493692 patent/DE1493692A1/de active Pending
-
1966
- 1966-01-17 NL NL6600574A patent/NL6600574A/xx unknown
- 1966-01-19 CH CH68166A patent/CH456626A/de unknown
- 1966-01-21 AT AT57966A patent/AT282080B/de active
- 1966-01-21 SE SE786/66A patent/SE319189B/xx unknown
- 1966-01-24 GB GB3106/66A patent/GB1132264A/en not_active Expired
- 1966-01-24 FR FR46948A patent/FR1481080A/fr not_active Expired
- 1966-01-24 BE BE675499D patent/BE675499A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL6600574A (enrdf_load_stackoverflow) | 1966-07-25 |
| BE675499A (enrdf_load_stackoverflow) | 1966-07-25 |
| AT282080B (de) | 1970-06-10 |
| SE319189B (enrdf_load_stackoverflow) | 1970-01-12 |
| CH456626A (de) | 1968-07-31 |
| DE1493692A1 (de) | 1969-10-23 |
| FR1481080A (fr) | 1967-05-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Schwyzer et al. | Total synthesis of adrenocorticotrophic hormone | |
| ES450439A1 (es) | Un metodo para preparar un peptido de somatostina. | |
| DK0646127T3 (da) | Polypeptidbombesinantagonister | |
| ES8703488A1 (es) | Procedimiento para preparar peptidos | |
| ES488382A1 (es) | Procedimiento para la preparacion de lh-rh o de analogos de lh-rh | |
| GB1132264A (en) | Process for purifying synthetically prepared peptides | |
| ES2076933T3 (es) | Nuevos sustratos peptidicos. | |
| US3862113A (en) | Process for the selective elimination of aralkyloxycarbonyl and trityl n-protecting groups with 2,2,2-trifluoroethanol | |
| DE2127393A1 (de) | Hepta- oder Octapeptide | |
| GB1278681A (en) | Peptides | |
| ES403973A1 (es) | Un procedimiento para la preparacion de monapeptidos. | |
| GB1002041A (en) | New polypeptides and process for their manufacture | |
| Seu et al. | Synthesis of Isoleucyl 5-alanyl 7-angiotensin II | |
| Kobayashi et al. | Oxytocin Analogues Containing No Disulfide Bond. I. Synthesis of the Lactam of l-Tyrosyl-l-isoleucyl-l-glutaminyl-l-asparaginyl-l-α-aminosuberyl-l-prolyl-l-leucylglycine Amide | |
| GB1173437A (en) | Pentacosapeptides | |
| ES295653A1 (es) | Un procedimiento para preparar una nueva clase de polipéptidos | |
| Stewart et al. | The search for peptides with specific antibradykinin activity | |
| ES417951A1 (es) | Un procedimiento para la preparacion de nuevos peptidos de actividades acth. | |
| GB1190077A (en) | Peptides and Process for Preparing them | |
| Nozaki et al. | Synthesis of tuftsin and its analogs. | |
| GB1140665A (en) | New peptides having an adrenocorticotropic hormone action and process for their manufacture | |
| GB1164618A (en) | Tetracosapeptides and Process for their Manufacture | |
| US3374218A (en) | Protected derivatives of physalaemin | |
| GB1231494A (enrdf_load_stackoverflow) | ||
| GB1273873A (en) | Corticotropically highly active octadecapeptides |