GB1118718A - Process for preparing derivatives of t-butyl ª‡-(3-indolyl)-acetate - Google Patents
Process for preparing derivatives of t-butyl ª‡-(3-indolyl)-acetateInfo
- Publication number
- GB1118718A GB1118718A GB2796166A GB2796166A GB1118718A GB 1118718 A GB1118718 A GB 1118718A GB 2796166 A GB2796166 A GB 2796166A GB 2796166 A GB2796166 A GB 2796166A GB 1118718 A GB1118718 A GB 1118718A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- butyl
- hydrogen chloride
- indolyl
- sulphonate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 title 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 5
- IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 abstract 3
- 229910000041 hydrogen chloride Inorganic materials 0.000 abstract 3
- DKGAVHZHDRPRBM-UHFFFAOYSA-N Tert-Butanol Chemical compound CC(C)(C)O DKGAVHZHDRPRBM-UHFFFAOYSA-N 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- JOVOSQBPPZZESK-UHFFFAOYSA-N phenylhydrazine hydrochloride Chemical compound Cl.NNC1=CC=CC=C1 JOVOSQBPPZZESK-UHFFFAOYSA-N 0.000 abstract 2
- 229940038531 phenylhydrazine hydrochloride Drugs 0.000 abstract 2
- FVXIMLWFYMZNEU-UHFFFAOYSA-N tert-butyl 4-oxopentanoate Chemical compound CC(=O)CCC(=O)OC(C)(C)C FVXIMLWFYMZNEU-UHFFFAOYSA-N 0.000 abstract 2
- HTTMKWDLOCUHFT-UHFFFAOYSA-N (4-tert-butyl-5-methoxy-2-methyl-1H-indol-3-yl) acetate Chemical compound C(C)(=O)OC1=C(NC2=CC=C(C(=C12)C(C)(C)C)OC)C HTTMKWDLOCUHFT-UHFFFAOYSA-N 0.000 abstract 1
- RKIDDEGICSMIJA-UHFFFAOYSA-N 4-chlorobenzoyl chloride Chemical compound ClC(=O)C1=CC=C(Cl)C=C1 RKIDDEGICSMIJA-UHFFFAOYSA-N 0.000 abstract 1
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 abstract 1
- KEAYESYHFKHZAL-UHFFFAOYSA-N Sodium Chemical compound [Na] KEAYESYHFKHZAL-UHFFFAOYSA-N 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000000908 ammonium hydroxide Substances 0.000 abstract 1
- JXLHNMVSKXFWAO-UHFFFAOYSA-N azane;7-fluoro-2,1,3-benzoxadiazole-4-sulfonic acid Chemical compound N.OS(=O)(=O)C1=CC=C(F)C2=NON=C12 JXLHNMVSKXFWAO-UHFFFAOYSA-N 0.000 abstract 1
- 239000002585 base Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- ZNSBPFFOQMIZIO-UHFFFAOYSA-N phenyl N-aminosulfamate Chemical compound NNS(=O)(=O)OC1=CC=CC=C1 ZNSBPFFOQMIZIO-UHFFFAOYSA-N 0.000 abstract 1
- 238000000197 pyrolysis Methods 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- 229910000104 sodium hydride Inorganic materials 0.000 abstract 1
- 239000012312 sodium hydride Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
- C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46862365A | 1965-06-30 | 1965-06-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1118718A true GB1118718A (en) | 1968-07-03 |
Family
ID=23860560
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2796166A Expired GB1118718A (en) | 1965-06-30 | 1966-06-22 | Process for preparing derivatives of t-butyl ª‡-(3-indolyl)-acetate |
Country Status (10)
| Country | Link |
|---|---|
| BE (1) | BE682962A (enrdf_load_stackoverflow) |
| BR (1) | BR6680628D0 (enrdf_load_stackoverflow) |
| CH (1) | CH480337A (enrdf_load_stackoverflow) |
| DE (1) | DE1620014C3 (enrdf_load_stackoverflow) |
| DK (1) | DK131818C (enrdf_load_stackoverflow) |
| FI (1) | FI50623C (enrdf_load_stackoverflow) |
| GB (1) | GB1118718A (enrdf_load_stackoverflow) |
| IL (1) | IL25997A (enrdf_load_stackoverflow) |
| NL (1) | NL6609138A (enrdf_load_stackoverflow) |
| SE (1) | SE312337B (enrdf_load_stackoverflow) |
-
1966
- 1966-06-20 IL IL2599766A patent/IL25997A/en unknown
- 1966-06-21 FI FI165566A patent/FI50623C/fi active
- 1966-06-22 BR BR18062866A patent/BR6680628D0/pt unknown
- 1966-06-22 BE BE682962D patent/BE682962A/xx unknown
- 1966-06-22 GB GB2796166A patent/GB1118718A/en not_active Expired
- 1966-06-29 SE SE886066A patent/SE312337B/xx unknown
- 1966-06-29 DK DK336066A patent/DK131818C/da active
- 1966-06-29 DE DE1966M0070017 patent/DE1620014C3/de not_active Expired
- 1966-06-29 CH CH941266A patent/CH480337A/de not_active IP Right Cessation
- 1966-06-30 NL NL6609138A patent/NL6609138A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI50623B (enrdf_load_stackoverflow) | 1976-02-02 |
| IL25997A (en) | 1970-02-19 |
| FI50623C (fi) | 1976-05-10 |
| SE312337B (enrdf_load_stackoverflow) | 1969-07-14 |
| DE1620014A1 (de) | 1970-06-25 |
| DK131818C (da) | 1976-02-09 |
| DK131818B (da) | 1975-09-08 |
| NL6609138A (enrdf_load_stackoverflow) | 1967-01-02 |
| BE682962A (enrdf_load_stackoverflow) | 1966-12-22 |
| BR6680628D0 (pt) | 1973-12-26 |
| DE1620014C3 (de) | 1980-01-17 |
| CH480337A (de) | 1969-10-31 |
| DE1620014B2 (de) | 1979-05-17 |
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