GB1117637A - Derivatives of the antibiotic circulin - Google Patents
Derivatives of the antibiotic circulinInfo
- Publication number
- GB1117637A GB1117637A GB5209865A GB5209865A GB1117637A GB 1117637 A GB1117637 A GB 1117637A GB 5209865 A GB5209865 A GB 5209865A GB 5209865 A GB5209865 A GB 5209865A GB 1117637 A GB1117637 A GB 1117637A
- Authority
- GB
- United Kingdom
- Prior art keywords
- circulin
- pentakis
- sulphomethyl
- hydroxymethyl
- ammonium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- YLHJFOAQDDQFIU-UHFFFAOYSA-N circulin Chemical compound CCC(C)C1NC(=O)C(CC(C)C)NC(=O)C(CCN)NC(=O)C(NC(=O)C(CCN)NC(=O)C(NC(=O)C(CCN)NC=O)C(C)O)CCNC(=O)C(C(C)O)NC(=O)C(CCN)NC(=O)C(CCN)NC1=O YLHJFOAQDDQFIU-UHFFFAOYSA-N 0.000 title abstract 13
- 108010002696 circulin Proteins 0.000 title abstract 13
- 230000003115 biocidal effect Effects 0.000 title abstract 3
- -1 amine salts Chemical class 0.000 abstract 7
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 abstract 3
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 229910052783 alkali metal Inorganic materials 0.000 abstract 2
- 150000001340 alkali metals Chemical class 0.000 abstract 2
- 239000007864 aqueous solution Substances 0.000 abstract 2
- 125000004029 hydroxymethyl group Chemical class [H]OC([H])([H])* 0.000 abstract 2
- 229910052751 metal Inorganic materials 0.000 abstract 2
- 239000002184 metal Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 abstract 1
- 235000019733 Fish meal Nutrition 0.000 abstract 1
- 241000607142 Salmonella Species 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- ZETCGWYACBNPIH-UHFFFAOYSA-N azane;sulfurous acid Chemical compound N.OS(O)=O ZETCGWYACBNPIH-UHFFFAOYSA-N 0.000 abstract 1
- 239000003729 cation exchange resin Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000011109 contamination Methods 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000004467 fishmeal Substances 0.000 abstract 1
- 238000004108 freeze drying Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000002244 precipitate Substances 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 229910021653 sulphate ion Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/60—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
- C07K7/62—Polymyxins; Related peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Fodder In General (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42795765A | 1965-01-25 | 1965-01-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1117637A true GB1117637A (en) | 1968-06-19 |
Family
ID=23696999
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5209865A Expired GB1117637A (en) | 1965-01-25 | 1965-12-08 | Derivatives of the antibiotic circulin |
Country Status (2)
| Country | Link |
|---|---|
| FR (1) | FR5578M (enrdf_load_html_response) |
| GB (1) | GB1117637A (enrdf_load_html_response) |
-
1965
- 1965-12-08 GB GB5209865A patent/GB1117637A/en not_active Expired
-
1966
- 1966-04-22 FR FR58694A patent/FR5578M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE1543936B2 (de) | 1973-01-04 |
| DE1543936A1 (de) | 1970-05-21 |
| FR5578M (enrdf_load_html_response) | 1967-11-27 |
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