GB1115335A - Dipotassium rhodizonate and the production thereof - Google Patents

Dipotassium rhodizonate and the production thereof

Info

Publication number
GB1115335A
GB1115335A GB28284/65A GB2828465A GB1115335A GB 1115335 A GB1115335 A GB 1115335A GB 28284/65 A GB28284/65 A GB 28284/65A GB 2828465 A GB2828465 A GB 2828465A GB 1115335 A GB1115335 A GB 1115335A
Authority
GB
United Kingdom
Prior art keywords
rhodizonate
dipotassium
pharmaceutical composition
solid
liquid carrier
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB28284/65A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IATROCHEMICAL INST OF PHAR
Shionogi and Co Ltd
Original Assignee
IATROCHEMICAL INST OF PHAR
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IATROCHEMICAL INST OF PHAR, Shionogi and Co Ltd filed Critical IATROCHEMICAL INST OF PHAR
Publication of GB1115335A publication Critical patent/GB1115335A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/713—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups a keto group being part of a six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Dipotassium rhodizonate <FORM:1115335/C2/1> is prepared by polycondensing glyoxal oxidatively in the presence of a potassium salt of carbonic acid and a potassium salt of sulphurous acid. Suitable salts are the carbonate, bicarbonate, sulphite and bisulphite. The condensation is carried out at a pH of 7.5-9.0 and is catalysed by potassium cyanide. The process is carried out in an aqueous solvent at room temperature or while heating in a stream of air or oxygen. Dipotassium rhodizonate has anti-diabetic activity and it can be made up into a pharmaceutical composition with a solid or liquid carrier (see Division A5).ALSO:A pharmaceutical composition for the treatment of diabetes comprises dipotassium rhodizonate together with a solid or liquid carrier. The compositions are made up into the form of tablets capsules, pills, suspensions and solutions.
GB28284/65A 1964-07-06 1965-07-05 Dipotassium rhodizonate and the production thereof Expired GB1115335A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3733864 1964-07-06

Publications (1)

Publication Number Publication Date
GB1115335A true GB1115335A (en) 1968-05-29

Family

ID=12494814

Family Applications (1)

Application Number Title Priority Date Filing Date
GB28284/65A Expired GB1115335A (en) 1964-07-06 1965-07-05 Dipotassium rhodizonate and the production thereof

Country Status (2)

Country Link
FR (1) FR4756M (en)
GB (1) GB1115335A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999028984A1 (en) * 1997-12-02 1999-06-10 Acep Inc. Novel electrode materials derived from polyquinoid ionic compounds and their uses in electrochemical generators
CN102531867A (en) * 2011-11-30 2012-07-04 泰山医学院 Rhodizonic acid raffinate reusing synthesis process
CN102531874A (en) * 2011-11-30 2012-07-04 泰山医学院 Rhodizonic acid catalytic synthesis process

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999028984A1 (en) * 1997-12-02 1999-06-10 Acep Inc. Novel electrode materials derived from polyquinoid ionic compounds and their uses in electrochemical generators
US6743877B1 (en) * 1997-12-02 2004-06-01 Acep Inc Electrode materials derived from polyquinonic ionic compounds and their use in electrochemical generators
US7879492B2 (en) * 1997-12-02 2011-02-01 Acep Inc. Electrode materials derived from polyquinonic ionic compounds and their use in electrochemical generators
US9722240B2 (en) 1997-12-02 2017-08-01 Acep Inc. Electrode materials derived from polyquinonic ionic compounds and their use in electrochemical generators
CN102531867A (en) * 2011-11-30 2012-07-04 泰山医学院 Rhodizonic acid raffinate reusing synthesis process
CN102531874A (en) * 2011-11-30 2012-07-04 泰山医学院 Rhodizonic acid catalytic synthesis process
CN102531867B (en) * 2011-11-30 2014-06-11 泰山医学院 Rhodizonic acid raffinate reusing synthesis process
CN102531874B (en) * 2011-11-30 2014-11-26 泰山医学院 Rhodizonic acid catalytic synthesis process

Also Published As

Publication number Publication date
FR4756M (en) 1967-01-16

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