GB1106059A - Novel benzofuran derivatives and a process for the manufacture thereof - Google Patents
Novel benzofuran derivatives and a process for the manufacture thereofInfo
- Publication number
- GB1106059A GB1106059A GB5321065A GB5321065A GB1106059A GB 1106059 A GB1106059 A GB 1106059A GB 5321065 A GB5321065 A GB 5321065A GB 5321065 A GB5321065 A GB 5321065A GB 1106059 A GB1106059 A GB 1106059A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- alkyl
- halo
- chloro
- converting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001907 coumarones Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 abstract 2
- 229910052783 alkali metal Inorganic materials 0.000 abstract 2
- -1 alkyl phenol Chemical compound 0.000 abstract 2
- 150000001412 amines Chemical class 0.000 abstract 2
- 125000001246 bromo group Chemical group Br* 0.000 abstract 2
- 150000003944 halohydrins Chemical class 0.000 abstract 2
- 125000005283 haloketone group Chemical group 0.000 abstract 2
- VKYKSIONXSXAKP-UHFFFAOYSA-N hexamethylenetetramine Chemical compound C1N(C2)CN3CN1CN2C3 VKYKSIONXSXAKP-UHFFFAOYSA-N 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 101100037762 Caenorhabditis elegans rnh-2 gene Proteins 0.000 abstract 1
- 229930040373 Paraformaldehyde Natural products 0.000 abstract 1
- 239000000674 adrenergic antagonist Substances 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- SMZOGRDCAXLAAR-UHFFFAOYSA-N aluminium isopropoxide Chemical compound [Al+3].CC(C)[O-].CC(C)[O-].CC(C)[O-] SMZOGRDCAXLAAR-UHFFFAOYSA-N 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- BULLHNJGPPOUOX-UHFFFAOYSA-N chloroacetone Chemical compound CC(=O)CCl BULLHNJGPPOUOX-UHFFFAOYSA-N 0.000 abstract 1
- GRTGGSXWHGKRSB-UHFFFAOYSA-N dichloromethyl methyl ether Chemical compound COC(Cl)Cl GRTGGSXWHGKRSB-UHFFFAOYSA-N 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 150000002118 epoxides Chemical class 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 235000010299 hexamethylene tetramine Nutrition 0.000 abstract 1
- 239000004312 hexamethylene tetramine Substances 0.000 abstract 1
- 229960004011 methenamine Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229920002866 paraformaldehyde Polymers 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000006187 pill Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
- XJDNKRIXUMDJCW-UHFFFAOYSA-J titanium tetrachloride Chemical compound Cl[Ti](Cl)(Cl)Cl XJDNKRIXUMDJCW-UHFFFAOYSA-J 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (16)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB5321065A GB1106059A (en) | 1965-12-15 | 1965-12-15 | Novel benzofuran derivatives and a process for the manufacture thereof |
IL2679566A IL26795A (en) | 1965-12-15 | 1966-11-02 | Benzofuran derivatives and process for the manufacture thereof |
CH1639166A CH477432A (de) | 1965-12-15 | 1966-11-14 | Verfahren zur Herstellung von Benzofuranderivaten |
DE19661543673 DE1543673C3 (de) | 1965-12-15 | 1966-11-16 | Basisch substituierte Benzofuranderivate und deren pharmazeutisch verträgliche Säureadditionssalze sowie Verfahren zu deren Herstellung und Arzneimittel mit einem Gehalt dieser Verbindungen |
NL6616724A NL6616724A (enrdf_load_stackoverflow) | 1965-12-15 | 1966-11-28 | |
FR85517A FR6045M (enrdf_load_stackoverflow) | 1965-12-15 | 1966-11-30 | |
FI324166A FI47660C (fi) | 1965-12-15 | 1966-12-07 | Menetelmä terapeuttisesti vaikuttavien bentsofuraanijohdannaisten valm istamiseksi. |
BE690934D BE690934A (enrdf_load_stackoverflow) | 1965-12-15 | 1966-12-09 | |
SE1721366A SE346105B (enrdf_load_stackoverflow) | 1965-12-15 | 1966-12-11 | |
FR86968A FR1504310A (fr) | 1965-12-15 | 1966-12-12 | Procédé pour la préparation de dérivés de benzofurane |
ES334476A ES334476A1 (es) | 1965-12-15 | 1966-12-13 | Procedimiento para la preparacion de derivados de benzofu- rano. |
BR18534866A BR6685348D0 (pt) | 1965-12-15 | 1966-12-14 | Processo para a preparacao de derivados de benzofurano |
NO16600066A NO120231B (enrdf_load_stackoverflow) | 1965-12-15 | 1966-12-14 | |
DK651166A DK123772B (da) | 1965-12-15 | 1966-12-15 | Analogifremgangsmåde til fremstilling af benzofuranderivater. |
MY6900390A MY6900390A (en) | 1965-12-15 | 1969-12-30 | Novel benzofuran derivatives and a process for the manufacture thereof |
US010645A US3929836A (en) | 1965-05-11 | 1970-02-11 | 2-(2-Lower alkylamino-1-hydroxy-ethyl)-substituted benzofurans |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB5321065A GB1106059A (en) | 1965-12-15 | 1965-12-15 | Novel benzofuran derivatives and a process for the manufacture thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1106059A true GB1106059A (en) | 1968-03-13 |
Family
ID=10466999
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB5321065A Expired GB1106059A (en) | 1965-05-11 | 1965-12-15 | Novel benzofuran derivatives and a process for the manufacture thereof |
Country Status (14)
-
1965
- 1965-12-15 GB GB5321065A patent/GB1106059A/en not_active Expired
-
1966
- 1966-11-02 IL IL2679566A patent/IL26795A/en unknown
- 1966-11-14 CH CH1639166A patent/CH477432A/de not_active IP Right Cessation
- 1966-11-16 DE DE19661543673 patent/DE1543673C3/de not_active Expired
- 1966-11-28 NL NL6616724A patent/NL6616724A/xx unknown
- 1966-11-30 FR FR85517A patent/FR6045M/fr not_active Expired
- 1966-12-07 FI FI324166A patent/FI47660C/fi active
- 1966-12-09 BE BE690934D patent/BE690934A/xx unknown
- 1966-12-11 SE SE1721366A patent/SE346105B/xx unknown
- 1966-12-12 FR FR86968A patent/FR1504310A/fr not_active Expired
- 1966-12-13 ES ES334476A patent/ES334476A1/es not_active Expired
- 1966-12-14 BR BR18534866A patent/BR6685348D0/pt unknown
- 1966-12-14 NO NO16600066A patent/NO120231B/no unknown
- 1966-12-15 DK DK651166A patent/DK123772B/da unknown
-
1969
- 1969-12-30 MY MY6900390A patent/MY6900390A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
DK123772B (da) | 1972-07-31 |
ES334476A1 (es) | 1968-02-01 |
DE1543673C3 (de) | 1975-05-28 |
CH477432A (de) | 1969-08-31 |
FR1504310A (fr) | 1967-12-01 |
BE690934A (enrdf_load_stackoverflow) | 1967-06-09 |
FR6045M (enrdf_load_stackoverflow) | 1968-05-20 |
FI47660B (enrdf_load_stackoverflow) | 1973-10-31 |
FI47660C (fi) | 1974-02-11 |
BR6685348D0 (pt) | 1973-12-27 |
MY6900390A (en) | 1969-12-31 |
IL26795A (en) | 1970-06-17 |
NL6616724A (enrdf_load_stackoverflow) | 1967-06-16 |
SE346105B (enrdf_load_stackoverflow) | 1972-06-26 |
DE1543673A1 (de) | 1969-09-11 |
NO120231B (enrdf_load_stackoverflow) | 1970-09-21 |
DE1543673B2 (de) | 1974-10-03 |
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