GB1102987A - Isoflavanoids - Google Patents
IsoflavanoidsInfo
- Publication number
- GB1102987A GB1102987A GB51947/65A GB5194765A GB1102987A GB 1102987 A GB1102987 A GB 1102987A GB 51947/65 A GB51947/65 A GB 51947/65A GB 5194765 A GB5194765 A GB 5194765A GB 1102987 A GB1102987 A GB 1102987A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- represent
- general formula
- product
- groups
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000004388 isoflavanoid group Chemical group 0.000 title 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- -1 tetrahydropyranyloxy Chemical group 0.000 abstract 3
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 2
- 229910004727 OSO3H Inorganic materials 0.000 abstract 2
- 125000003277 amino group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000002373 5 membered heterocyclic group Chemical group 0.000 abstract 1
- 125000004070 6 membered heterocyclic group Chemical group 0.000 abstract 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 230000002152 alkylating effect Effects 0.000 abstract 1
- 125000003368 amide group Chemical group 0.000 abstract 1
- MDFFNEOEWAXZRQ-UHFFFAOYSA-N aminyl Chemical compound [NH2] MDFFNEOEWAXZRQ-UHFFFAOYSA-N 0.000 abstract 1
- 230000003509 anti-fertility effect Effects 0.000 abstract 1
- 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 239000003433 contraceptive agent Substances 0.000 abstract 1
- 230000002254 contraceptive effect Effects 0.000 abstract 1
- 125000004185 ester group Chemical group 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- NNQSGBRGJHSRFN-UHFFFAOYSA-N isoflavan Chemical compound C1OC2=CC=CC=C2CC1C1=CC=CC=C1 NNQSGBRGJHSRFN-UHFFFAOYSA-N 0.000 abstract 1
- 235000002324 isoflavanes Nutrition 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 1
- 150000002902 organometallic compounds Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/6552—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
- C07F9/65522—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3066867A GB1102988A (en) | 1965-01-02 | 1965-12-07 | 4-aryl-isoflavanoids and production thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEM0063676 | 1965-01-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1102987A true GB1102987A (en) | 1968-02-14 |
Family
ID=7310873
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB51947/65A Expired GB1102987A (en) | 1965-01-02 | 1965-12-07 | Isoflavanoids |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US3471520A (hu) |
| BE (1) | BE674534A (hu) |
| BR (1) | BR6576150D0 (hu) |
| CH (1) | CH469697A (hu) |
| DE (1) | DE1518002C3 (hu) |
| DK (1) | DK111268B (hu) |
| FR (1) | FR5046M (hu) |
| GB (1) | GB1102987A (hu) |
| IL (1) | IL24787A (hu) |
| NL (1) | NL6517021A (hu) |
| SE (1) | SE350040B (hu) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4053626A (en) * | 1973-03-13 | 1977-10-11 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Cholesterol level-lowering phenoxyacetic acids |
| US4133883A (en) * | 1975-06-03 | 1979-01-09 | Beecham Group Limited | Polycyclic chromenes useful as antidepressants and anorexics |
| GB1493998A (en) * | 1975-06-03 | 1977-12-07 | Beecham Group Ltd | Propanolamine derivatives |
| US5395842A (en) * | 1988-10-31 | 1995-03-07 | Endorecherche Inc. | Anti-estrogenic compounds and compositions |
| US5686465A (en) * | 1988-10-31 | 1997-11-11 | Endorecherche Inc. | Sex steroid activity inhibitors |
| US5254568A (en) * | 1990-08-09 | 1993-10-19 | Council Of Scientific & Industrial Research | Benzopyrans as antiestrogenic agents |
| US6060503A (en) * | 1991-12-02 | 2000-05-09 | Endorecherche, Inc. | Benzopyran-containing compounds and method for their use |
| AU683838B2 (en) * | 1992-05-19 | 1997-11-27 | Novogen Research Pty Ltd | Health supplements containing phyto-oestrogens, analogues or metabolites thereof |
| US5389646A (en) * | 1993-12-30 | 1995-02-14 | Zymogenetics, Inc. | Methods for treatment and prevention of bone loss using 2,3-benzopyrans |
| AUPO203996A0 (en) * | 1996-08-30 | 1996-09-26 | Novogen Research Pty Ltd | Therapeutic uses |
| US6146668A (en) | 1997-04-28 | 2000-11-14 | Novogen, Inc. | Preparation of isoflavones from legumes |
| NZ527735A (en) * | 1997-05-01 | 2005-10-28 | Novogen Inc | Treatment or prevention of menopausal symptoms and osteoporosis |
| AUPP112497A0 (en) * | 1997-12-24 | 1998-01-22 | Novogen Research Pty Ltd | Compositions and method for protecting skin from UV induced immunosupression and skin damage |
| AUPP260798A0 (en) * | 1998-03-26 | 1998-04-23 | Novogen Research Pty Ltd | Treatment of medical related conditions with isoflavone containing extracts of clover |
| AUPP868599A0 (en) * | 1999-02-15 | 1999-03-11 | Novogen Research Pty Ltd | Production of isoflavone derivatives |
| AUPQ266199A0 (en) * | 1999-09-06 | 1999-09-30 | Novogen Research Pty Ltd | Compositions and therapeutic methods involving isoflavones and analogues thereof |
| US20090233999A1 (en) * | 1999-09-06 | 2009-09-17 | Novogen Research Pty Ltd | Compositions and therapeutic methods involving isoflavones and analogues thereof |
| AUPQ520300A0 (en) * | 2000-01-21 | 2000-02-17 | Novogen Research Pty Ltd | Food product and process |
| CN1261431C (zh) * | 2001-01-24 | 2006-06-28 | 奇斯药制品公司 | 2h－1－苯并吡喃衍生物、它们的制备方法及其药物组合物 |
| AUPR363301A0 (en) * | 2001-03-08 | 2001-04-05 | Novogen Research Pty Ltd | Dimeric isoflavones |
| US20050119301A1 (en) * | 2001-03-16 | 2005-06-02 | Alan Husband | Treatment of restenosis |
| ES2377073T3 (es) * | 2004-09-21 | 2012-03-22 | Marshall Edwards, Inc. | Derivados de cromano sustituidos, medicamentos y utilización en terapia |
| CA2581316C (en) | 2004-09-21 | 2013-09-10 | Novogen Research Pty Ltd | Substituted chroman derivatives, medicaments and use in therapy |
| US8080675B2 (en) | 2004-09-21 | 2011-12-20 | Marshall Edwards, Inc. | Chroman derivatives, medicaments and use in therapy |
| EP2635121B1 (en) | 2010-11-01 | 2020-01-08 | MEI Pharma, Inc. | Isoflavonoid compounds and methods for the treatment of cancer |
| CN107427003B (zh) | 2015-02-02 | 2023-01-31 | 梅制药公司 | 联合治疗 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3142682A (en) * | 1961-11-21 | 1964-07-28 | Ciba Geigy Corp | Tertiary amino derivatives of chromans and homo-chromans |
| US3340276A (en) * | 1964-04-01 | 1967-09-05 | Ciba Geigy Corp | 3, 4-diphenyl-chromans |
| US3340277A (en) * | 1964-06-24 | 1967-09-05 | Ciba Geigy Corp | Phenyl-chromenes |
-
1965
- 1965-01-02 DE DE1518002A patent/DE1518002C3/de not_active Expired
- 1965-11-11 CH CH1556465A patent/CH469697A/de unknown
- 1965-12-07 GB GB51947/65A patent/GB1102987A/en not_active Expired
- 1965-12-14 IL IL24787A patent/IL24787A/xx unknown
- 1965-12-28 NL NL6517021A patent/NL6517021A/xx unknown
- 1965-12-29 SE SE16891/65A patent/SE350040B/xx unknown
- 1965-12-29 DK DK667765AA patent/DK111268B/da unknown
- 1965-12-30 US US517782A patent/US3471520A/en not_active Expired - Lifetime
- 1965-12-30 BR BR176150/65A patent/BR6576150D0/pt unknown
- 1965-12-30 BE BE674534D patent/BE674534A/xx unknown
- 1965-12-31 FR FR44499A patent/FR5046M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CH469697A (de) | 1969-03-15 |
| BR6576150D0 (pt) | 1973-09-06 |
| FR5046M (hu) | 1967-05-02 |
| NL6517021A (hu) | 1966-07-04 |
| IL24787A (en) | 1969-11-30 |
| SE350040B (hu) | 1972-10-16 |
| US3471520A (en) | 1969-10-07 |
| DE1518002B2 (de) | 1974-04-11 |
| DE1518002A1 (de) | 1969-06-19 |
| DK111268B (da) | 1968-07-15 |
| BE674534A (hu) | 1966-06-30 |
| DE1518002C3 (de) | 1975-01-23 |
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