GB1191465A - A process for the preparation of Dicarboxylic Acid Derivatives of Substituted S-Triazines - Google Patents

A process for the preparation of Dicarboxylic Acid Derivatives of Substituted S-Triazines

Info

Publication number
GB1191465A
GB1191465A GB23139/67A GB2313967A GB1191465A GB 1191465 A GB1191465 A GB 1191465A GB 23139/67 A GB23139/67 A GB 23139/67A GB 2313967 A GB2313967 A GB 2313967A GB 1191465 A GB1191465 A GB 1191465A
Authority
GB
United Kingdom
Prior art keywords
piperazino
dicarboxylic acid
substituted
triazines
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB23139/67A
Inventor
Werner Heimberger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Evonik Operations GmbH
Original Assignee
Degussa GmbH
Deutsche Gold und Silber Scheideanstalt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa GmbH, Deutsche Gold und Silber Scheideanstalt filed Critical Degussa GmbH
Publication of GB1191465A publication Critical patent/GB1191465A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

1,191,465. Triazine ester-acids. DEUTSCHE GOLDUND SILBER-SCHEIDEANSTALT. 18 May, 1967 [21 May, 1966], No. 23139/67. Heading C2C. Novel compounds of formula wherein R<SP>1</SP> and R<SP>2</SP> are each C 1-4 alkoxy, C 1-4 alkylthio, monoalkylamino, mono(hydroxyalkyl)amino, Cl, CCl 3 , CHCl 2 , morpholino, piperazino or N-(C 1-4 alkyl)-piperazino, and R<SP>3</SP> is wherein n is 1-6, Alk is C 1-4 alkylene, X is O or NH and A is H, C 1-4 alkyl, alkali metal, ¢-alkaline earth metal, or substituted ammonium derived from a tertiary organic base, are prepared by reacting a compound of Formula I wherein R<SP>3</SP> is -NH-Alk-X-H or piperazino with an appropriate dicarboxylic acid anhydride or ester-halide, optionally in the presence of an appropriate base. Products wherein A is other than H may subsequently be hydrolysed to the free acids.
GB23139/67A 1966-05-21 1967-05-18 A process for the preparation of Dicarboxylic Acid Derivatives of Substituted S-Triazines Expired GB1191465A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DED0050171 1966-05-21

Publications (1)

Publication Number Publication Date
GB1191465A true GB1191465A (en) 1970-05-13

Family

ID=7052449

Family Applications (1)

Application Number Title Priority Date Filing Date
GB23139/67A Expired GB1191465A (en) 1966-05-21 1967-05-18 A process for the preparation of Dicarboxylic Acid Derivatives of Substituted S-Triazines

Country Status (10)

Country Link
US (1) US3536709A (en)
BE (1) BE698747A (en)
CH (1) CH522658A (en)
DE (1) DE1670525A1 (en)
DK (1) DK119561B (en)
FR (1) FR7026M (en)
GB (1) GB1191465A (en)
IL (1) IL27910A (en)
NL (1) NL6706966A (en)
SE (1) SE336343B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0330263A1 (en) * 1988-02-25 1989-08-30 Merck & Co. Inc. Piperazinylalkylpyrimidines as hypoglycemic agents
US4980350A (en) * 1988-02-25 1990-12-25 Merck & Co., Inc. Piperazinylalkylpyrimidines as hypoglycemic agents

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3697520A (en) * 1970-04-30 1972-10-10 Ciba Geigy Ag Triazine carboxylic acids and esters
BR112015022504A2 (en) 2013-03-13 2017-07-18 A Reichard Gregory triazine compounds and compositions thereof and methods for treating malaria and chemoprophylaxis

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0330263A1 (en) * 1988-02-25 1989-08-30 Merck & Co. Inc. Piperazinylalkylpyrimidines as hypoglycemic agents
US4980350A (en) * 1988-02-25 1990-12-25 Merck & Co., Inc. Piperazinylalkylpyrimidines as hypoglycemic agents

Also Published As

Publication number Publication date
DE1670525A1 (en) 1971-12-09
BE698747A (en) 1967-11-03
CH522658A (en) 1972-06-30
NL6706966A (en) 1967-11-22
FR7026M (en) 1969-06-09
IL27910A (en) 1971-12-29
DK119561B (en) 1971-01-25
US3536709A (en) 1970-10-27
SE336343B (en) 1971-07-05

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PLNP Patent lapsed through nonpayment of renewal fees