GB1102880A - 1,4-benzodioxane derivatives and their preparation - Google Patents
1,4-benzodioxane derivatives and their preparationInfo
- Publication number
- GB1102880A GB1102880A GB45397/66A GB4539766A GB1102880A GB 1102880 A GB1102880 A GB 1102880A GB 45397/66 A GB45397/66 A GB 45397/66A GB 4539766 A GB4539766 A GB 4539766A GB 1102880 A GB1102880 A GB 1102880A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- methoxyphenyl
- propanol
- reacting
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- BNBQRQQYDMDJAH-UHFFFAOYSA-N benzodioxan Chemical class C1=CC=C2OCCOC2=C1 BNBQRQQYDMDJAH-UHFFFAOYSA-N 0.000 title 1
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 6
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 5
- 125000004172 4-methoxyphenyl group Chemical group [H]C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1* 0.000 abstract 3
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- GAIQXBPCVWNGFF-UHFFFAOYSA-N 2,6-bis(phenylmethoxy)phenol Chemical compound C1=CC=C(OCC=2C=CC=CC=2)C(O)=C1OCC1=CC=CC=C1 GAIQXBPCVWNGFF-UHFFFAOYSA-N 0.000 abstract 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- YCIMNLLNPGFGHC-UHFFFAOYSA-N catechol Chemical compound OC1=CC=CC=C1O YCIMNLLNPGFGHC-UHFFFAOYSA-N 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 229910052740 iodine Inorganic materials 0.000 abstract 2
- UKWHYYKOEPRTIC-UHFFFAOYSA-N mercury(ii) oxide Chemical compound [Hg]=O UKWHYYKOEPRTIC-UHFFFAOYSA-N 0.000 abstract 2
- -1 methylenedioxy group Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- PWMWNFMRSKOCEY-UHFFFAOYSA-N 1-Phenyl-1,2-ethanediol Chemical compound OCC(O)C1=CC=CC=C1 PWMWNFMRSKOCEY-UHFFFAOYSA-N 0.000 abstract 1
- RIGCHQASOPMIAU-UHFFFAOYSA-N 1-[2,6-bis(phenylmethoxy)phenoxy]-1-phenylpropan-1-ol Chemical compound C1(=CC=CC=C1)C(CC)(O)OC1=C(C=CC=C1OCC1=CC=CC=C1)OCC1=CC=CC=C1 RIGCHQASOPMIAU-UHFFFAOYSA-N 0.000 abstract 1
- IGQQQAUZPNTQFP-UHFFFAOYSA-N 1-chloro-1-phenylpropan-1-ol Chemical compound CCC(O)(Cl)C1=CC=CC=C1 IGQQQAUZPNTQFP-UHFFFAOYSA-N 0.000 abstract 1
- AZUCWOCEESVRJM-UHFFFAOYSA-N 2-[1-hydroxy-1-(4-methoxyphenyl)propan-2-yl]benzene-1,3-diol Chemical compound COC1=CC=C(C=C1)C(O)C(C)C1=C(O)C=CC=C1O AZUCWOCEESVRJM-UHFFFAOYSA-N 0.000 abstract 1
- GJLHVTLBSGTWGG-UHFFFAOYSA-N 2-iodo-1-(4-methoxyphenyl)propan-1-ol Chemical compound COC1=CC=C(C=C1)C(O)C(C)I GJLHVTLBSGTWGG-UHFFFAOYSA-N 0.000 abstract 1
- YVCOJTATJWDGEU-UHFFFAOYSA-N 2-methyl-3-phenyloxirane Chemical compound CC1OC1C1=CC=CC=C1 YVCOJTATJWDGEU-UHFFFAOYSA-N 0.000 abstract 1
- 125000002373 5 membered heterocyclic group Chemical group 0.000 abstract 1
- 125000004070 6 membered heterocyclic group Chemical group 0.000 abstract 1
- QROGIFZRVHSFLM-QHHAFSJGSA-N [(e)-prop-1-enyl]benzene Chemical compound C\C=C\C1=CC=CC=C1 QROGIFZRVHSFLM-QHHAFSJGSA-N 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000002152 alkylating effect Effects 0.000 abstract 1
- 230000003509 anti-fertility effect Effects 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 230000001076 estrogenic effect Effects 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 abstract 1
- 239000011630 iodine Substances 0.000 abstract 1
- GRVDJDISBSALJP-UHFFFAOYSA-N methyloxidanyl Chemical compound [O]C GRVDJDISBSALJP-UHFFFAOYSA-N 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 238000011200 topical administration Methods 0.000 abstract 1
- RUVINXPYWBROJD-ONEGZZNKSA-N trans-anethole Chemical compound COC1=CC=C(\C=C\C)C=C1 RUVINXPYWBROJD-ONEGZZNKSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEM0067235 | 1965-11-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1102880A true GB1102880A (en) | 1968-02-14 |
Family
ID=7312111
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB45397/66A Expired GB1102880A (en) | 1965-11-11 | 1966-10-11 | 1,4-benzodioxane derivatives and their preparation |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US3484448A (cg-RX-API-DMAC10.html) |
| BE (1) | BE689496A (cg-RX-API-DMAC10.html) |
| BR (1) | BR6684443D0 (cg-RX-API-DMAC10.html) |
| CH (1) | CH503015A (cg-RX-API-DMAC10.html) |
| DE (1) | DE1518042C3 (cg-RX-API-DMAC10.html) |
| DK (1) | DK114839B (cg-RX-API-DMAC10.html) |
| ES (1) | ES333241A1 (cg-RX-API-DMAC10.html) |
| FR (1) | FR5928M (cg-RX-API-DMAC10.html) |
| GB (1) | GB1102880A (cg-RX-API-DMAC10.html) |
| IL (1) | IL26708A (cg-RX-API-DMAC10.html) |
| NL (1) | NL6615198A (cg-RX-API-DMAC10.html) |
| SE (1) | SE355363B (cg-RX-API-DMAC10.html) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0221725A3 (en) * | 1985-10-23 | 1988-03-23 | Glaxo Group Limited | Process for preparing heterocyclic compounds |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4056540A (en) * | 1974-01-01 | 1977-11-01 | Bristol-Myers Company | 4-Phenyl-1,3-benzodioxans |
| DE2428680C2 (de) * | 1974-06-14 | 1983-02-17 | Dr. Madaus & Co, 5000 Köln | 1-(2',4',6'-Trihydroxyphenyl)-propandion-(1,2)-Verbindungen, Verfahren zu deren Herstellung und Arzneimittel, die diese Verbindungen enthalten |
| US4146650A (en) * | 1978-04-26 | 1979-03-27 | The United States Of America As Represented By The Secretary Of Agriculture | Substituted benzodioxan sweetening compound |
| AU2002306687A1 (en) * | 2001-03-13 | 2002-09-24 | Glenmark Pharmaceuticals Limited | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1964973A (en) * | 1931-09-16 | 1934-07-03 | Winthrop Chem Co Inc | 1 (3' 4' dioxyalkylene phenyl) 2 aminoalkanol (1) |
-
1965
- 1965-11-11 DE DE1518042A patent/DE1518042C3/de not_active Expired
-
1966
- 1966-01-10 ES ES0333241A patent/ES333241A1/es not_active Expired
- 1966-09-08 CH CH1300166A patent/CH503015A/de not_active IP Right Cessation
- 1966-10-11 GB GB45397/66A patent/GB1102880A/en not_active Expired
- 1966-10-17 IL IL6626708A patent/IL26708A/en unknown
- 1966-10-25 FR FR81482A patent/FR5928M/fr not_active Expired
- 1966-10-27 NL NL6615198A patent/NL6615198A/xx unknown
- 1966-11-07 US US592319A patent/US3484448A/en not_active Expired - Lifetime
- 1966-11-09 BE BE689496D patent/BE689496A/xx unknown
- 1966-11-10 BR BR184443/66A patent/BR6684443D0/pt unknown
- 1966-11-11 DK DK586566AA patent/DK114839B/da unknown
- 1966-11-11 SE SE15446/66A patent/SE355363B/xx unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0221725A3 (en) * | 1985-10-23 | 1988-03-23 | Glaxo Group Limited | Process for preparing heterocyclic compounds |
Also Published As
| Publication number | Publication date |
|---|---|
| CH503015A (de) | 1971-02-15 |
| FR5928M (cg-RX-API-DMAC10.html) | 1968-04-01 |
| BR6684443D0 (pt) | 1973-12-18 |
| SE355363B (cg-RX-API-DMAC10.html) | 1973-04-16 |
| NL6615198A (cg-RX-API-DMAC10.html) | 1967-05-12 |
| US3484448A (en) | 1969-12-16 |
| DE1518042A1 (de) | 1969-06-12 |
| IL26708A (en) | 1970-08-19 |
| DK114839B (da) | 1969-08-11 |
| ES333241A1 (es) | 1967-09-01 |
| BE689496A (cg-RX-API-DMAC10.html) | 1967-05-19 |
| DE1518042B2 (de) | 1974-08-22 |
| DE1518042C3 (de) | 1975-04-10 |
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