GB1096959A - Improvements in or relating to 3-keto steroid compounds of the 9ª, 10ª-series - Google Patents
Improvements in or relating to 3-keto steroid compounds of the 9ª, 10ª-seriesInfo
- Publication number
- GB1096959A GB1096959A GB40034/67A GB4003467A GB1096959A GB 1096959 A GB1096959 A GB 1096959A GB 40034/67 A GB40034/67 A GB 40034/67A GB 4003467 A GB4003467 A GB 4003467A GB 1096959 A GB1096959 A GB 1096959A
- Authority
- GB
- United Kingdom
- Prior art keywords
- relating
- series
- steroid compounds
- keto steroid
- bisdehydro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- YEWSFUFGMDJFFG-QAGGRKNESA-N (8r,9s,10r,13s,14s)-10,13-dimethyl-2,8,9,11,12,14,15,16-octahydro-1h-cyclopenta[a]phenanthrene-3,17-dione Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3C=CC2=C1 YEWSFUFGMDJFFG-QAGGRKNESA-N 0.000 abstract 1
- LJNASASDNLCNOS-ADBSWBDJSA-N (8s,9s,10r,13r,14s,17r)-17-[(e,2r,5r)-5,6-dimethylhept-3-en-2-yl]-10,13-dimethyl-1,2,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one Chemical compound C1=CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)/C=C/[C@H](C)C(C)C)[C@@]1(C)CC2 LJNASASDNLCNOS-ADBSWBDJSA-N 0.000 abstract 1
- JGMOKGBVKVMRFX-LEKSSAKUSA-N (8s,9s,10r,13s,14s,17s)-17-acetyl-10,13-dimethyl-1,2,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one Chemical class C1=CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 JGMOKGBVKVMRFX-LEKSSAKUSA-N 0.000 abstract 1
- YEWSFUFGMDJFFG-UHFFFAOYSA-N (9beta,10alpha)-Androsta-4,6-diene-3,17-dione Natural products O=C1CCC2(C)C3CCC(C)(C(CC4)=O)C4C3C=CC2=C1 YEWSFUFGMDJFFG-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- LJNASASDNLCNOS-UHFFFAOYSA-N Isoergosteron Natural products C1=CC2=CC(=O)CCC2(C)C2C1C1CCC(C(C)C=CC(C)C(C)C)C1(C)CC2 LJNASASDNLCNOS-UHFFFAOYSA-N 0.000 abstract 1
- 229930194542 Keto Natural products 0.000 abstract 1
- -1 aliphatic alcohols Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910000039 hydrogen halide Inorganic materials 0.000 abstract 1
- 239000012433 hydrogen halide Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J15/00—Stereochemically pure steroids containing carbon, hydrogen, halogen or oxygen having a partially or totally inverted skeleton, e.g. retrosteroids, L-isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL63301566A NL146503B (nl) | 1963-12-09 | 1963-12-09 | Werkwijze voor de bereiding van een 9beta, 10alfa-pregna-4,6-dieen-3,20-dion. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1096959A true GB1096959A (en) | 1967-12-29 |
Family
ID=19755277
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB50106/64A Expired GB1096958A (en) | 1963-12-09 | 1964-12-09 | Improvements in or relating to 9ª,10ª-steroid compounds |
| GB40034/67A Expired GB1096959A (en) | 1963-12-09 | 1964-12-09 | Improvements in or relating to 3-keto steroid compounds of the 9ª, 10ª-series |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB50106/64A Expired GB1096958A (en) | 1963-12-09 | 1964-12-09 | Improvements in or relating to 9ª,10ª-steroid compounds |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US3364205A (en:Method) |
| AT (1) | AT266336B (en:Method) |
| BR (1) | BR6465078D0 (en:Method) |
| CH (1) | CH491898A (en:Method) |
| CS (1) | CS150524B2 (en:Method) |
| DE (1) | DE1468427C3 (en:Method) |
| DK (1) | DK118818B (en:Method) |
| ES (1) | ES306848A1 (en:Method) |
| FI (1) | FI42326B (en:Method) |
| GB (2) | GB1096958A (en:Method) |
| NL (1) | NL146503B (en:Method) |
| SE (2) | SE335336B (en:Method) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016154772A1 (zh) * | 2015-04-02 | 2016-10-06 | 台州市海盛制药有限公司 | 9β，10α-孕甾-4，6-二烯-3，20-二酮的制备方法 |
| CN110790808B (zh) * | 2019-11-19 | 2022-10-28 | 湖南新合新生物医药有限公司 | 一种5,7-孕甾二烯-3,20-二酮-二乙二缩酮的制备方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL112521C (en:Method) * | 1960-05-30 |
-
1963
- 1963-12-09 NL NL63301566A patent/NL146503B/xx not_active IP Right Cessation
-
1964
- 1964-12-04 BR BR165078/64A patent/BR6465078D0/pt unknown
- 1964-12-05 DK DK599464AA patent/DK118818B/da unknown
- 1964-12-07 SE SE14769/64A patent/SE335336B/xx unknown
- 1964-12-07 AT AT1033564A patent/AT266336B/de active
- 1964-12-07 FI FI2578/64A patent/FI42326B/fi active
- 1964-12-07 DE DE1468427A patent/DE1468427C3/de not_active Expired
- 1964-12-07 CH CH1586264A patent/CH491898A/de not_active IP Right Cessation
- 1964-12-07 ES ES0306848A patent/ES306848A1/es not_active Expired
- 1964-12-08 CS CS6877A patent/CS150524B2/cs unknown
- 1964-12-08 US US416744A patent/US3364205A/en not_active Expired - Lifetime
- 1964-12-09 GB GB50106/64A patent/GB1096958A/en not_active Expired
- 1964-12-09 GB GB40034/67A patent/GB1096959A/en not_active Expired
-
1966
- 1966-12-07 SE SE12855/66A patent/SE330532B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE1468427C3 (de) | 1974-05-02 |
| GB1096958A (en) | 1967-12-29 |
| BR6465078D0 (pt) | 1973-08-02 |
| DK118818B (da) | 1970-10-12 |
| US3364205A (en) | 1968-01-16 |
| SE335336B (en:Method) | 1971-05-24 |
| DE1468427B2 (de) | 1973-09-27 |
| DE1468427A1 (de) | 1970-01-08 |
| NL146503B (nl) | 1975-07-15 |
| AT266336B (de) | 1968-11-11 |
| FI42326B (en:Method) | 1970-03-31 |
| ES306848A1 (es) | 1965-05-16 |
| CS150524B2 (en:Method) | 1973-09-04 |
| SE330532B (en:Method) | 1970-11-23 |
| CH491898A (de) | 1970-06-15 |
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