NL146503B - Werkwijze voor de bereiding van een 9beta, 10alfa-pregna-4,6-dieen-3,20-dion. - Google Patents

Werkwijze voor de bereiding van een 9beta, 10alfa-pregna-4,6-dieen-3,20-dion.

Info

Publication number
NL146503B
NL146503B NL63301566A NL301566A NL146503B NL 146503 B NL146503 B NL 146503B NL 63301566 A NL63301566 A NL 63301566A NL 301566 A NL301566 A NL 301566A NL 146503 B NL146503 B NL 146503B
Authority
NL
Netherlands
Prior art keywords
10alfa
dieen
9beta
pregna
dion
Prior art date
Application number
NL63301566A
Other languages
English (en)
Inventor
Theodorus Reinder Dr Rix
Original Assignee
Philips Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philips Nv filed Critical Philips Nv
Priority to NL63301566A priority Critical patent/NL146503B/nl
Priority to BR165078/64A priority patent/BR6465078D0/pt
Priority to DK599464AA priority patent/DK118818B/da
Priority to DE1468427A priority patent/DE1468427C3/de
Priority to FI2578/64A priority patent/FI42326B/fi
Priority to SE14769/64A priority patent/SE335336B/xx
Priority to AT1033564A priority patent/AT266336B/de
Priority to CH1586264A priority patent/CH491898A/de
Priority to CH553869A priority patent/CH483417A/de
Priority to ES0306848A priority patent/ES306848A1/es
Priority to CS6877A priority patent/CS150524B2/cs
Priority to FR997894A priority patent/FR1430922A/fr
Priority to US416744A priority patent/US3364205A/en
Priority to GB40034/67A priority patent/GB1096959A/en
Priority to GB50106/64A priority patent/GB1096958A/en
Priority to SE12855/66A priority patent/SE330532B/xx
Publication of NL146503B publication Critical patent/NL146503B/nl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J15/00—Stereochemically pure steroids containing carbon, hydrogen, halogen or oxygen having a partially or totally inverted skeleton, e.g. retrosteroids, L-isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NL63301566A 1963-12-09 1963-12-09 Werkwijze voor de bereiding van een 9beta, 10alfa-pregna-4,6-dieen-3,20-dion. NL146503B (nl)

Priority Applications (16)

Application Number Priority Date Filing Date Title
NL63301566A NL146503B (nl) 1963-12-09 1963-12-09 Werkwijze voor de bereiding van een 9beta, 10alfa-pregna-4,6-dieen-3,20-dion.
BR165078/64A BR6465078D0 (pt) 1963-12-09 1964-12-04 Processo de producao de um esteroide 3-ceto-4 6-bisdeshidro-9-beta-10-alfa
DK599464AA DK118818B (da) 1963-12-09 1964-12-05 Fremgangsmåde til fremstilling af 3-keto-4,6-bisdehydro-9β,10α-steroider.
DE1468427A DE1468427C3 (de) 1963-12-09 1964-12-07 Verfahren zur Herstellung von 3-Keto-4,6-bisdehydro-9beta-, lOalpha -steroiden
FI2578/64A FI42326B (nl) 1963-12-09 1964-12-07
SE14769/64A SE335336B (nl) 1963-12-09 1964-12-07
AT1033564A AT266336B (de) 1963-12-09 1964-12-07 Verfahren zur Herstellung von 3-Keto-4,6-bisdehydro-9-β,10α-steroiden
CH1586264A CH491898A (de) 1963-12-09 1964-12-07 Verfahren zur Herstellung eines 3-Keto-4,6-bisdehydro-9B,10a-steroids
CH553869A CH483417A (de) 1963-12-09 1964-12-07 Verfahren zur Herstellung eines 3-Keto-4,6-bisdehydro-9B, 10x-steroids
ES0306848A ES306848A1 (es) 1963-12-09 1964-12-07 Un metodo de producir un 3-ceto-4,6-bisdehidro 9 beta,10 alfa-esteroide.
CS6877A CS150524B2 (nl) 1963-12-09 1964-12-08
FR997894A FR1430922A (fr) 1963-12-09 1964-12-08 Nouveaux stéroïdes à configuration 9 beta. 10 alpha, leur préparation et leurs applications
US416744A US3364205A (en) 1963-12-09 1964-12-08 Method of producing a 3-keto-4, 6-bisdehydro-9beta, 10alpha-steroid and intermediates obtained therefrom
GB40034/67A GB1096959A (en) 1963-12-09 1964-12-09 Improvements in or relating to 3-keto steroid compounds of the 9ª‰, 10ª‡-series
GB50106/64A GB1096958A (en) 1963-12-09 1964-12-09 Improvements in or relating to 9ª‰,10ª‡-steroid compounds
SE12855/66A SE330532B (nl) 1963-12-09 1966-12-07

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL63301566A NL146503B (nl) 1963-12-09 1963-12-09 Werkwijze voor de bereiding van een 9beta, 10alfa-pregna-4,6-dieen-3,20-dion.

Publications (1)

Publication Number Publication Date
NL146503B true NL146503B (nl) 1975-07-15

Family

ID=19755277

Family Applications (1)

Application Number Title Priority Date Filing Date
NL63301566A NL146503B (nl) 1963-12-09 1963-12-09 Werkwijze voor de bereiding van een 9beta, 10alfa-pregna-4,6-dieen-3,20-dion.

Country Status (12)

Country Link
US (1) US3364205A (nl)
AT (1) AT266336B (nl)
BR (1) BR6465078D0 (nl)
CH (1) CH491898A (nl)
CS (1) CS150524B2 (nl)
DE (1) DE1468427C3 (nl)
DK (1) DK118818B (nl)
ES (1) ES306848A1 (nl)
FI (1) FI42326B (nl)
GB (2) GB1096959A (nl)
NL (1) NL146503B (nl)
SE (2) SE335336B (nl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016154772A1 (zh) * 2015-04-02 2016-10-06 台州市海盛制药有限公司 9β，10α-孕甾-4，6-二烯-3，20-二酮的制备方法
CN110790808B (zh) * 2019-11-19 2022-10-28 湖南新合新生物医药有限公司 一种5,7-孕甾二烯-3,20-二酮-二乙二缩酮的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL112521C (nl) * 1960-05-30

Also Published As

Publication number Publication date
CH491898A (de) 1970-06-15
GB1096959A (en) 1967-12-29
DE1468427C3 (de) 1974-05-02
AT266336B (de) 1968-11-11
FI42326B (nl) 1970-03-31
DE1468427A1 (de) 1970-01-08
DE1468427B2 (de) 1973-09-27
CS150524B2 (nl) 1973-09-04
GB1096958A (en) 1967-12-29
BR6465078D0 (pt) 1973-08-02
ES306848A1 (es) 1965-05-16
SE335336B (nl) 1971-05-24
DK118818B (da) 1970-10-12
SE330532B (nl) 1970-11-23
US3364205A (en) 1968-01-16

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Legal Events

Date Code Title Description
NL80 Information provided on patent owner name for an already discontinued patent

Owner name: DUPHAR

V4 Discontinued because of reaching the maximum lifetime of a patent