GB1085692A - Compounds containing protected amino groups and process for preparing the same - Google Patents
Compounds containing protected amino groups and process for preparing the sameInfo
- Publication number
- GB1085692A GB1085692A GB21185/66A GB2118566A GB1085692A GB 1085692 A GB1085692 A GB 1085692A GB 21185/66 A GB21185/66 A GB 21185/66A GB 2118566 A GB2118566 A GB 2118566A GB 1085692 A GB1085692 A GB 1085692A
- Authority
- GB
- United Kingdom
- Prior art keywords
- dimethoxybenzoxycarbonyl
- alkyl
- substituted
- dimethoxybenzyloxycarbonyl
- glycine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 title abstract 8
- 125000003277 amino group Chemical group 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 7
- -1 imidazolylmethyl Chemical class 0.000 abstract 4
- RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical compound C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 abstract 3
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 abstract 2
- AUDBREYGQOXIFT-UHFFFAOYSA-N (3,5-dimethoxyphenyl)methanol Chemical compound COC1=CC(CO)=CC(OC)=C1 AUDBREYGQOXIFT-UHFFFAOYSA-N 0.000 abstract 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 2
- OAKJQQAXSVQMHS-UHFFFAOYSA-N Hydrazine Chemical compound NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 abstract 2
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 abstract 2
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 abstract 2
- 235000004279 alanine Nutrition 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- YBRPWHZMSWNKTC-MRXNPFEDSA-N (2R)-2-[(3,5-dimethoxyphenyl)methoxycarbonylamino]-2-phenylacetic acid Chemical compound COC=1C=C(COC(=O)N[C@H](C2=CC=CC=C2)C(=O)O)C=C(C=1)OC YBRPWHZMSWNKTC-MRXNPFEDSA-N 0.000 abstract 1
- GSZZXNUMOLTFSU-UHFFFAOYSA-N (3,5-dimethoxyphenyl)methyl carbonochloridate Chemical compound COC1=CC(COC(Cl)=O)=CC(OC)=C1 GSZZXNUMOLTFSU-UHFFFAOYSA-N 0.000 abstract 1
- NXLNNXIXOYSCMB-UHFFFAOYSA-N (4-nitrophenyl) carbonochloridate Chemical compound [O-][N+](=O)C1=CC=C(OC(Cl)=O)C=C1 NXLNNXIXOYSCMB-UHFFFAOYSA-N 0.000 abstract 1
- LOVPHSMOAVXQIH-UHFFFAOYSA-N (4-nitrophenyl) hydrogen carbonate Chemical class OC(=O)OC1=CC=C([N+]([O-])=O)C=C1 LOVPHSMOAVXQIH-UHFFFAOYSA-N 0.000 abstract 1
- LJXOMNKURQBXLP-SECBINFHSA-N 2-[[(2r)-2-azaniumyl-2-phenylacetyl]amino]acetate Chemical compound OC(=O)CNC(=O)[C@H](N)C1=CC=CC=C1 LJXOMNKURQBXLP-SECBINFHSA-N 0.000 abstract 1
- 229930182831 D-valine Natural products 0.000 abstract 1
- 239000004470 DL Methionine Substances 0.000 abstract 1
- 239000004471 Glycine Substances 0.000 abstract 1
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 abstract 1
- ZGUNAGUHMKGQNY-ZETCQYMHSA-N L-alpha-phenylglycine zwitterion Chemical compound OC(=O)[C@@H](N)C1=CC=CC=C1 ZGUNAGUHMKGQNY-ZETCQYMHSA-N 0.000 abstract 1
- IOVCWXUNBOPUCH-UHFFFAOYSA-M Nitrite anion Chemical compound [O-]N=O IOVCWXUNBOPUCH-UHFFFAOYSA-M 0.000 abstract 1
- YGYAWVDWMABLBF-UHFFFAOYSA-N Phosgene Chemical compound ClC(Cl)=O YGYAWVDWMABLBF-UHFFFAOYSA-N 0.000 abstract 1
- 229940024606 amino acid Drugs 0.000 abstract 1
- 235000001014 amino acid Nutrition 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 150000001540 azides Chemical class 0.000 abstract 1
- 125000000852 azido group Chemical group *N=[N+]=[N-] 0.000 abstract 1
- 125000001797 benzyl group Chemical class [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 238000006193 diazotization reaction Methods 0.000 abstract 1
- 125000002541 furyl group Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000006301 indolyl methyl group Chemical class 0.000 abstract 1
- FFEARJCKVFRZRR-UHFFFAOYSA-N methionine Chemical compound CSCCC(N)C(O)=O FFEARJCKVFRZRR-UHFFFAOYSA-N 0.000 abstract 1
- 229930182817 methionine Natural products 0.000 abstract 1
- 235000006109 methionine Nutrition 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000001997 phenyl group Chemical class [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 108700034597 phenylglycylglycine Proteins 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
- 229960001153 serine Drugs 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 125000001544 thienyl group Chemical class 0.000 abstract 1
- 229960004441 tyrosine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
- C07K1/063—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for alpha-amino functions
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45530765A | 1965-05-12 | 1965-05-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1085692A true GB1085692A (en) | 1967-10-04 |
Family
ID=23808282
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB21185/66A Expired GB1085692A (en) | 1965-05-12 | 1966-05-12 | Compounds containing protected amino groups and process for preparing the same |
Country Status (6)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3944590A (en) * | 1967-01-25 | 1976-03-16 | Ciba-Geigy Corporation | Process for the temporary protection of amino groups in peptide syntheses |
| US4394519A (en) * | 1982-01-19 | 1983-07-19 | Research Corporation | Amino acid blocking agents |
| FR2559764B1 (fr) * | 1984-02-16 | 1988-01-29 | Poudres & Explosifs Ste Nale | Nouveaux carbonates a-chlores, leur procede de fabrication et leur application a la protection des fonctions amine des amino-acides |
| JP3440305B2 (ja) * | 1997-04-02 | 2003-08-25 | 高砂香料工業株式会社 | ７−（ｎ−置換アミノ）−２−フェニルヘプタン酸 エステル誘導体及び該誘導体の製造方法 |
| US7794495B2 (en) * | 2006-07-17 | 2010-09-14 | Advanced Cardiovascular Systems, Inc. | Controlled degradation of stents |
-
1965
- 1965-05-12 US US455307A patent/US3467690A/en not_active Expired - Lifetime
-
1966
- 1966-05-04 DE DE1793698A patent/DE1793698C2/de not_active Expired
- 1966-05-04 DE DE1568452A patent/DE1568452C3/de not_active Expired
- 1966-05-10 BE BE680797D patent/BE680797A/xx unknown
- 1966-05-10 CH CH674666A patent/CH462191A/de unknown
- 1966-05-12 GB GB21185/66A patent/GB1085692A/en not_active Expired
- 1966-05-12 BR BR179455/66A patent/BR6679455D0/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US3467690A (en) | 1969-09-16 |
| DE1568452B2 (de) | 1973-03-15 |
| BE680797A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1966-11-10 |
| BR6679455D0 (pt) | 1973-09-06 |
| DE1793698C2 (de) | 1973-10-18 |
| CH462191A (de) | 1968-09-15 |
| DE1568452A1 (de) | 1972-03-09 |
| DE1568452C3 (de) | 1973-10-25 |
| DE1793698B1 (de) | 1973-03-15 |
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