GB1085031A - Improvements in or relating to organic iron compounds - Google Patents
Improvements in or relating to organic iron compoundsInfo
- Publication number
- GB1085031A GB1085031A GB35529/64A GB3552964A GB1085031A GB 1085031 A GB1085031 A GB 1085031A GB 35529/64 A GB35529/64 A GB 35529/64A GB 3552964 A GB3552964 A GB 3552964A GB 1085031 A GB1085031 A GB 1085031A
- Authority
- GB
- United Kingdom
- Prior art keywords
- iron
- trivalent
- soluble
- acid
- prepared
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002506 iron compounds Chemical class 0.000 title 1
- XEEYBQQBJWHFJM-UHFFFAOYSA-N iron Substances [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 3
- 229910052742 iron Inorganic materials 0.000 abstract 3
- VAMXMNNIEUEQDV-UHFFFAOYSA-N methyl anthranilate Chemical compound COC(=O)C1=CC=CC=C1N VAMXMNNIEUEQDV-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- NEAQRZUHTPSBBM-UHFFFAOYSA-N 2-hydroxy-3,3-dimethyl-7-nitro-4h-isoquinolin-1-one Chemical compound C1=C([N+]([O-])=O)C=C2C(=O)N(O)C(C)(C)CC2=C1 NEAQRZUHTPSBBM-UHFFFAOYSA-N 0.000 abstract 1
- 239000004215 Carbon black (E152) Substances 0.000 abstract 1
- CWYNVVGOOAEACU-UHFFFAOYSA-N Fe2+ Chemical compound [Fe+2] CWYNVVGOOAEACU-UHFFFAOYSA-N 0.000 abstract 1
- AVXURJPOCDRRFD-UHFFFAOYSA-N Hydroxylamine Chemical compound ON AVXURJPOCDRRFD-UHFFFAOYSA-N 0.000 abstract 1
- 239000007983 Tris buffer Substances 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 150000002505 iron Chemical class 0.000 abstract 1
- 229940102398 methyl anthranilate Drugs 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000002798 polar solvent Substances 0.000 abstract 1
- UTRQCTRGGOEAOH-UHFFFAOYSA-N potassium 2-amino-N-oxidobenzamide Chemical compound C(C=1C(N)=CC=CC1)(=O)N[O-].[K+] UTRQCTRGGOEAOH-UHFFFAOYSA-N 0.000 abstract 1
- 238000009877 rendering Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/02—Iron compounds
- C07F15/025—Iron compounds without a metal-carbon linkage
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
Abstract
Organic iron complexes especially trisanthranilhydroxamato-iro (trivalent), [bis-chloro-l-leucine-hydroxamato-iron (trivalent)] acid and tris - nicotinhydroxamato - iron (trivalent) are prepared by reacting in a polar solvent a soluble ferrous or ferric salt with a hydroxyamic acid of the formula R.CONHOMe or a soluble salt thereof, wherein R is a heterocyclic radical or a substituted or unsubstituted hydrocarbon radical having up to 18 C atoms inclusive and containing 1, 2 or 3 amino groups and Me is H or a cation rendering the said hydroxamic acid soluble, and then optionally oxidizing the reaction product. Potassium anthranilhydroxamate is prepared from methyl anthranilate and hydroxylamine in the presence of KOH. Pharmaceutical compositions suitable for use in iron therapy comprise the complexes of the invention and a carrier therefor.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEB0073381 | 1963-09-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1085031A true GB1085031A (en) | 1967-09-27 |
Family
ID=6977834
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB35529/64A Expired GB1085031A (en) | 1963-09-04 | 1964-08-31 | Improvements in or relating to organic iron compounds |
Country Status (6)
| Country | Link |
|---|---|
| AT (1) | AT257635B (en) |
| BE (1) | BE652545A (en) |
| CH (1) | CH426775A (en) |
| FR (1) | FR3831M (en) |
| GB (1) | GB1085031A (en) |
| NL (1) | NL6409735A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016198285A1 (en) * | 2015-06-09 | 2016-12-15 | Nestec S.A. | Iron nicotinate composition |
-
1964
- 1964-06-10 AT AT498464A patent/AT257635B/en active
- 1964-06-18 CH CH722764A patent/CH426775A/en unknown
- 1964-08-21 NL NL6409735A patent/NL6409735A/xx unknown
- 1964-08-31 GB GB35529/64A patent/GB1085031A/en not_active Expired
- 1964-09-01 FR FR986741A patent/FR3831M/en not_active Expired
- 1964-09-01 BE BE652545D patent/BE652545A/xx unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016198285A1 (en) * | 2015-06-09 | 2016-12-15 | Nestec S.A. | Iron nicotinate composition |
Also Published As
| Publication number | Publication date |
|---|---|
| AT257635B (en) | 1967-10-10 |
| NL6409735A (en) | 1965-03-05 |
| CH426775A (en) | 1966-12-31 |
| FR3831M (en) | 1966-01-10 |
| BE652545A (en) | 1964-12-31 |
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