GB1084009A - Derivatives of 1,2,3,4-tetrahydro-9-aminoacridine - Google Patents
Derivatives of 1,2,3,4-tetrahydro-9-aminoacridineInfo
- Publication number
- GB1084009A GB1084009A GB36297/66A GB3629766A GB1084009A GB 1084009 A GB1084009 A GB 1084009A GB 36297/66 A GB36297/66 A GB 36297/66A GB 3629766 A GB3629766 A GB 3629766A GB 1084009 A GB1084009 A GB 1084009A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- anion
- hydrogen atom
- cations
- valencies
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- YLJREFDVOIBQDA-UHFFFAOYSA-N tacrine Chemical class C1=CC=C2C(N)=C(CCCC3)C3=NC2=C1 YLJREFDVOIBQDA-UHFFFAOYSA-N 0.000 title abstract 2
- 150000001450 anions Chemical class 0.000 abstract 7
- 150000001875 compounds Chemical class 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 150000001768 cations Chemical class 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- SQGYOTSLMSWVJD-UHFFFAOYSA-N silver(1+) nitrate Chemical compound [Ag+].[O-]N(=O)=O SQGYOTSLMSWVJD-UHFFFAOYSA-N 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- MNWXAVRGTAHVIM-UHFFFAOYSA-K C(CC(O)(C(=O)[O-])CC(=O)[O-])(=O)[O-].[Ag+].[Na+].[Na+] Chemical compound C(CC(O)(C(=O)[O-])CC(=O)[O-])(=O)[O-].[Ag+].[Na+].[Na+] MNWXAVRGTAHVIM-UHFFFAOYSA-K 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000000443 aerosol Substances 0.000 abstract 1
- 229910001413 alkali metal ion Inorganic materials 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 230000000843 anti-fungal effect Effects 0.000 abstract 1
- PXBRQCKWGAHEHS-UHFFFAOYSA-N dichlorodifluoromethane Chemical compound FC(F)(Cl)Cl PXBRQCKWGAHEHS-UHFFFAOYSA-N 0.000 abstract 1
- 235000019404 dichlorodifluoromethane Nutrition 0.000 abstract 1
- 235000019441 ethanol Nutrition 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229910001961 silver nitrate Inorganic materials 0.000 abstract 1
- 239000001509 sodium citrate Substances 0.000 abstract 1
- HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 abstract 1
- 229940038773 trisodium citrate Drugs 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C07D219/08—Nitrogen atoms
- C07D219/10—Nitrogen atoms attached in position 9
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Medicinal Preparation (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEB83330A DE1253269B (de) | 1965-08-18 | 1965-08-18 | Verfahren zur Herstellung von antimikrobiell wirksamen Bis-1, 2, 3, 4-tetrahydro-9-aminoacridiniumverbindungen |
| DEB0083329 | 1965-08-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1084009A true GB1084009A (en) | 1967-09-20 |
Family
ID=25967659
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB36297/66A Expired GB1084009A (en) | 1965-08-18 | 1966-08-12 | Derivatives of 1,2,3,4-tetrahydro-9-aminoacridine |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US3519631A (enExample) |
| BE (1) | BE685630A (enExample) |
| CH (2) | CH487894A (enExample) |
| DE (2) | DE1253269B (enExample) |
| DK (1) | DK115114B (enExample) |
| ES (2) | ES330189A1 (enExample) |
| FR (2) | FR5809M (enExample) |
| GB (1) | GB1084009A (enExample) |
| NL (1) | NL6611621A (enExample) |
| SE (1) | SE328576B (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816456A (en) * | 1986-10-01 | 1989-03-28 | Summers William K | Administration of monoamine acridines in cholinergic neuronal deficit states |
| IL87861A0 (en) * | 1987-10-05 | 1989-03-31 | Pfizer | 4-aminopyridine derivatives |
| EP0430968B1 (en) * | 1988-05-02 | 1996-11-20 | PHANOS TECHNOLOGIES, Inc. | Compounds, compositions and method for binding bio-affecting substances to surface membranes of bio-particles |
| ES2402789T3 (es) * | 2006-11-20 | 2013-05-08 | President And Fellows Of Harvard College | Métodos, composicones y kits para tratar dolor y prurito |
| CA2767646C (en) | 2009-07-10 | 2019-01-29 | President And Fellows Of Harvard College | Permanently charged sodium and calcium channel blockers as anti-inflammatory agents |
| GB201002413D0 (en) | 2010-02-12 | 2010-03-31 | Procarta Biosystems Ltd | Nucleic acid complexes |
| GB201005545D0 (en) | 2010-04-01 | 2010-05-19 | Procarta Biosystems Ltd | Transcription factor decoys |
| ES2702487T3 (es) | 2011-06-17 | 2019-03-01 | Nantenergy Inc | Líquido iónico que contiene iones sulfonato |
| CN108348774A (zh) | 2015-08-03 | 2018-07-31 | 哈佛大学校长及研究员协会 | 带电离子通道阻断剂及其应用 |
| US11424484B2 (en) | 2019-01-24 | 2022-08-23 | Octet Scientific, Inc. | Zinc battery electrolyte additive |
| SG11202109713PA (en) | 2019-03-11 | 2021-10-28 | Nocion Therapeutics Inc | Ester substituted ion channel blockers and methods for use |
| US10786485B1 (en) | 2019-03-11 | 2020-09-29 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| JP7692834B2 (ja) | 2019-03-11 | 2025-06-16 | ノシオン セラピューティクス，インコーポレイテッド | 荷電したイオンチャンネル遮断薬および使用方法 |
| JP7678757B2 (ja) | 2019-03-11 | 2025-05-16 | ノシオン セラピューティクス，インコーポレイテッド | 荷電したイオンチャンネル遮断薬および使用方法 |
| US10780083B1 (en) | 2019-03-11 | 2020-09-22 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| BR112022008575A2 (pt) | 2019-11-06 | 2022-08-09 | Nocion Therapeutics Inc | Bloqueadores de canal iônico carregado e métodos para uso |
| CA3155568A1 (en) | 2019-11-06 | 2021-05-14 | Bridget Mccarthy Cole | Charged ion channel blockers and methods for use |
| US12162851B2 (en) | 2020-03-11 | 2024-12-10 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| KR20230022830A (ko) | 2020-03-11 | 2023-02-16 | 녹시온 테라퓨틱스 인코포레이티드 | 하전된 이온 채널 차단제 및 사용 방법 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2108765A (en) * | 1938-02-15 | Preserving and disinfecting media | ||
| US2152047A (en) * | 1939-03-28 | Preserving and disinfecting media | ||
| US2295504A (en) * | 1938-08-01 | 1942-09-08 | Wm S Merrell Co | Cetyl quaternary ammonium compound |
| US2485162A (en) * | 1946-04-08 | 1949-10-18 | Us Sec War | 7-chloro-4-(1-ethyl-4-piperidylamino)-quinoline |
| US2791588A (en) * | 1953-02-20 | 1957-05-07 | Allen & Hanburys Ltd | Alpha:omega-bisquinolinium compounds |
| US2791582A (en) * | 1953-11-12 | 1957-05-07 | Allen & Hanburys Ltd | Polyalkylene bis-1 |
| US3066141A (en) * | 1957-04-26 | 1962-11-27 | Jr Ralph Jones | Quinoline-type mustards and process for producing same |
| US3075981A (en) * | 1958-04-03 | 1963-01-29 | Sterling Drug Inc | 1-[aromatic-(lower-alkyl)]-4-(aromaticimino)-1, 4-dihydroquinolines and their preparation |
| US2948728A (en) * | 1958-10-15 | 1960-08-09 | Grace W R & Co | Quinoline and acridine compounds |
| US3027378A (en) * | 1959-06-26 | 1962-03-27 | Stark Hans Carl | Method of preparing nu4, nu4'-alkylene-n1, n1'-alkylene-bis-4-aminoquinaldinium-dihalides and resultant products |
| US3147182A (en) * | 1961-03-20 | 1964-09-01 | Johnson & Johnson | Antiseptic mixture of decamethylene 1, 10-bis-4-aminoquinaldinium salt and cetyl pridinium salt |
| US3232945A (en) * | 1962-08-13 | 1966-02-01 | S E Massengill Company | 7,8,9,10-tetrahalo-6h-cyclohepta-(b)-quinolines |
| US3346579A (en) * | 1966-04-25 | 1967-10-10 | Squibb & Sons Inc | Iodine chloride complexes of quinoline and acridine compounds |
-
0
- DE DENDAT1251764D patent/DE1251764B/de active Pending
-
1965
- 1965-08-18 DE DEB83330A patent/DE1253269B/de active Pending
-
1966
- 1966-07-18 SE SE11181/66*A patent/SE328576B/xx unknown
- 1966-08-04 CH CH1125466A patent/CH487894A/de unknown
- 1966-08-04 CH CH836269A patent/CH484138A/de unknown
- 1966-08-12 ES ES0330189A patent/ES330189A1/es not_active Expired
- 1966-08-12 GB GB36297/66A patent/GB1084009A/en not_active Expired
- 1966-08-16 US US572664A patent/US3519631A/en not_active Expired - Lifetime
- 1966-08-17 BE BE685630D patent/BE685630A/xx unknown
- 1966-08-17 FR FR73306A patent/FR5809M/fr not_active Expired
- 1966-08-17 DK DK422266AA patent/DK115114B/da unknown
- 1966-08-17 FR FR73307A patent/FR1516781A/fr not_active Expired
- 1966-08-18 NL NL6611621A patent/NL6611621A/xx unknown
-
1967
- 1967-05-29 ES ES341127A patent/ES341127A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NL6611621A (enExample) | 1967-02-20 |
| CH484138A (de) | 1970-01-15 |
| FR1516781A (fr) | 1968-02-05 |
| ES330189A1 (es) | 1967-09-01 |
| SE328576B (enExample) | 1970-09-21 |
| DE1253269B (de) | 1967-11-02 |
| BE685630A (enExample) | 1967-02-17 |
| DK115114B (da) | 1969-09-08 |
| ES341127A1 (es) | 1968-10-01 |
| CH487894A (de) | 1970-03-31 |
| US3519631A (en) | 1970-07-07 |
| FR5809M (enExample) | 1968-02-19 |
| DE1251764B (de) | 1967-10-12 |
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