GB1080979A - New thiepin and wxepin derivatives - Google Patents
New thiepin and wxepin derivativesInfo
- Publication number
- GB1080979A GB1080979A GB46426/65A GB4642665A GB1080979A GB 1080979 A GB1080979 A GB 1080979A GB 46426/65 A GB46426/65 A GB 46426/65A GB 4642665 A GB4642665 A GB 4642665A GB 1080979 A GB1080979 A GB 1080979A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- compounds
- group
- atom
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 alkyl radical Chemical class 0.000 abstract 9
- 150000001875 compounds Chemical class 0.000 abstract 9
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 6
- 125000004432 carbon atom Chemical group C* 0.000 abstract 4
- 125000005277 alkyl imino group Chemical group 0.000 abstract 3
- 125000001841 imino group Chemical group [H]N=* 0.000 abstract 3
- 229910052757 nitrogen Inorganic materials 0.000 abstract 3
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 2
- 239000005864 Sulphur Substances 0.000 abstract 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
- 239000000460 chlorine Substances 0.000 abstract 2
- 229910052801 chlorine Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical group [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 abstract 2
- 150000007522 mineralic acids Chemical class 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- 150000007524 organic acids Chemical class 0.000 abstract 2
- 239000001301 oxygen Substances 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 241000575946 Ione Species 0.000 abstract 1
- LTXREWYXXSTFRX-QGZVFWFLSA-N Linagliptin Chemical compound N=1C=2N(C)C(=O)N(CC=3N=C4C=CC=CC4=C(C)N=3)C(=O)C=2N(CC#CC)C=1N1CCC[C@@H](N)C1 LTXREWYXXSTFRX-QGZVFWFLSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 230000002908 adrenolytic effect Effects 0.000 abstract 1
- 150000003973 alkyl amines Chemical class 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- KMAWVRYYKYVCNR-UHFFFAOYSA-N benzo[b][1]benzothiepine Chemical compound C1=CC2=CC=CC=C2SC2=CC=CC=C21 KMAWVRYYKYVCNR-UHFFFAOYSA-N 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 125000001246 bromo group Chemical group Br* 0.000 abstract 1
- 239000006227 byproduct Substances 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 230000003001 depressive effect Effects 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 150000002440 hydroxy compounds Chemical class 0.000 abstract 1
- 150000002736 metal compounds Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- ATYBXHSAIOKLMG-UHFFFAOYSA-N oxepin Chemical compound O1C=CC=CC=C1 ATYBXHSAIOKLMG-UHFFFAOYSA-N 0.000 abstract 1
- 150000003254 radicals Chemical class 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D313/14—[b,f]-condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
- C07D337/02—Seven-membered rings
- C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D337/14—[b,f]-condensed
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1421164A CH440318A (de) | 1964-11-03 | 1964-11-03 | Verfahren zur Herstellung von neuen Thiepin- und Oxepinderivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1080979A true GB1080979A (en) | 1967-08-31 |
Family
ID=4398870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB46426/65A Expired GB1080979A (en) | 1964-11-03 | 1965-11-02 | New thiepin and wxepin derivatives |
Country Status (13)
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5780501A (en) * | 1995-02-08 | 1998-07-14 | Novartis Corporation | Treatment method using anti-neurodegeneratively active 10-aminoaliphatyl-dibenz b,f!oxepines |
| WO2003057204A3 (en) * | 2002-01-08 | 2004-02-05 | Nordic Bioscience As | Modulation of iamt (pimt or pcmt) in immune system |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2020207A1 (en) * | 1968-10-09 | 1970-07-10 | Leo Ab | CNS-active tri:cyclic amino:ketone(s) |
| CH501007A (de) * | 1968-11-27 | 1970-12-31 | Ciba Geigy Ag | Verfahren zur Herstellung von neuen Thiepin- und Oxepinderivaten |
-
1964
- 1964-11-03 CH CH1421164A patent/CH440318A/de unknown
-
1965
- 1965-10-26 FI FI652550A patent/FI43319C/fi active
- 1965-11-02 GB GB46426/65A patent/GB1080979A/en not_active Expired
- 1965-11-02 NL NL6514187A patent/NL6514187A/xx unknown
- 1965-11-02 ES ES0319156A patent/ES319156A1/es not_active Expired
- 1965-11-02 DK DK561565AA patent/DK109565C/da active
- 1965-11-02 SE SE14127/65A patent/SE315598B/xx unknown
- 1965-11-02 AT AT986265A patent/AT254879B/de active
- 1965-11-02 DE DEG45082A patent/DE1300954B/de active Pending
- 1965-11-03 FR FR37079A patent/FR1453003A/fr not_active Expired
- 1965-11-03 IL IL24558A patent/IL24558A/xx unknown
- 1965-11-03 BR BR174511/65A patent/BR6574511D0/pt unknown
- 1965-11-03 BE BE671752D patent/BE671752A/xx unknown
-
1966
- 1966-02-02 FR FR48142A patent/FR5388M/fr not_active Expired
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5780501A (en) * | 1995-02-08 | 1998-07-14 | Novartis Corporation | Treatment method using anti-neurodegeneratively active 10-aminoaliphatyl-dibenz b,f!oxepines |
| US5780500A (en) * | 1995-02-08 | 1998-07-14 | Novartis Corporation | Anti-neurodegeneratively active 10-aminoaliphatyl-dibenzi b,f! oxepines |
| WO2003057204A3 (en) * | 2002-01-08 | 2004-02-05 | Nordic Bioscience As | Modulation of iamt (pimt or pcmt) in immune system |
Also Published As
| Publication number | Publication date |
|---|---|
| NL6514187A (enrdf_load_stackoverflow) | 1966-05-04 |
| ES319156A1 (es) | 1966-07-01 |
| DE1300954B (de) | 1969-08-14 |
| FR1453003A (fr) | 1966-04-15 |
| AT254879B (de) | 1967-06-12 |
| FI43319C (fi) | 1971-03-10 |
| DK109565C (da) | 1968-05-13 |
| BR6574511D0 (pt) | 1973-08-16 |
| FI43319B (enrdf_load_stackoverflow) | 1970-11-30 |
| BE671752A (enrdf_load_stackoverflow) | 1966-05-03 |
| IL24558A (en) | 1969-09-25 |
| CH440318A (de) | 1967-07-31 |
| SE315598B (enrdf_load_stackoverflow) | 1969-10-06 |
| FR5388M (enrdf_load_stackoverflow) | 1967-09-18 |
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