GB1070675A - New cyclic ureide compounds and methods for their production - Google Patents

New cyclic ureide compounds and methods for their production

Info

Publication number
GB1070675A
GB1070675A GB2799765A GB2799765A GB1070675A GB 1070675 A GB1070675 A GB 1070675A GB 2799765 A GB2799765 A GB 2799765A GB 2799765 A GB2799765 A GB 2799765A GB 1070675 A GB1070675 A GB 1070675A
Authority
GB
United Kingdom
Prior art keywords
formula
compound
reacting
compounds
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2799765A
Inventor
Peter John Islip
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Parke Davis and Co LLC
Original Assignee
Parke Davis and Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Parke Davis and Co LLC filed Critical Parke Davis and Co LLC
Priority to GB2799765A priority Critical patent/GB1070675A/en
Publication of GB1070675A publication Critical patent/GB1070675A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/58Nitro radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

The invention comprises compounds of the formula <FORM:1070675/C2/1> wherein n is 1 or 2 and R is a hydrogen atom or a C1- 9 alkyl, allyl, propargyl or benzyl group, and processes for their preparation comprising (a) cyclizing a compound of the formula <FORM:1070675/C2/2> in which X is chlorine or bromine, to obtain a compound of the formula <FORM:1070675/C2/3> and, if desired, reacting this compound with an appropriate alkylating, alkenylating, alkynylating or benzylating agent, or (b) reacting a compound of the formula <FORM:1070675/C2/4> wherein R2 represents a hydrogen atom or a C1- 9 alkyl group, with a nitrating agent, e.g. a mixture of fuming nitric acid and sulphuric acid. Compounds of the Formula IX are prepared by reacting 2-aminothiazole with an isocyanate of the formula <FORM:1070675/C2/5> wherein X represents a chlorine or a bromine atom, to form a 2-thiazolylurea compound of the formula <FORM:1070675/C2/6> cyclizing this compound and, if desired, alkylating the resulting cyclized product.
GB2799765A 1965-07-01 1965-07-01 New cyclic ureide compounds and methods for their production Expired GB1070675A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB2799765A GB1070675A (en) 1965-07-01 1965-07-01 New cyclic ureide compounds and methods for their production

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2799765A GB1070675A (en) 1965-07-01 1965-07-01 New cyclic ureide compounds and methods for their production

Publications (1)

Publication Number Publication Date
GB1070675A true GB1070675A (en) 1967-06-01

Family

ID=10268617

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2799765A Expired GB1070675A (en) 1965-07-01 1965-07-01 New cyclic ureide compounds and methods for their production

Country Status (1)

Country Link
GB (1) GB1070675A (en)

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