GB1068058A - Process for the manufacture of í¸-16ª-methylsteroids and new í¸-16ª-methylsteroids - Google Patents
Process for the manufacture of í¸-16ª-methylsteroids and new í¸-16ª-methylsteroidsInfo
- Publication number
- GB1068058A GB1068058A GB41756/64A GB4175664A GB1068058A GB 1068058 A GB1068058 A GB 1068058A GB 41756/64 A GB41756/64 A GB 41756/64A GB 4175664 A GB4175664 A GB 4175664A GB 1068058 A GB1068058 A GB 1068058A
- Authority
- GB
- United Kingdom
- Prior art keywords
- methylsteroids
- chloro
- manufacture
- methyl
- acetate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- JRNVZBWKYDBUCA-UHFFFAOYSA-N N-chlorosuccinimide Chemical compound ClN1C(=O)CCC1=O JRNVZBWKYDBUCA-UHFFFAOYSA-N 0.000 abstract 2
- VLTRZXGMWDSKGL-UHFFFAOYSA-N perchloric acid Chemical compound OCl(=O)(=O)=O VLTRZXGMWDSKGL-UHFFFAOYSA-N 0.000 abstract 2
- YPGDRXCWTPTLRJ-FSEDFMJGSA-N (8S,9S,10R,11S,13R,14S,17R)-17-(2-hydroxyethyl)-10,13-dimethyl-6,7,8,9,11,12,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-11-ol Chemical compound C(C[C@H]1CC[C@H]2[C@@H]3CCC4=CCC=C[C@]4(C)[C@H]3[C@H](C[C@]12C)O)O YPGDRXCWTPTLRJ-FSEDFMJGSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 229940043232 butyl acetate Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- IUGYQRQAERSCNH-UHFFFAOYSA-M pivalate Chemical compound CC(C)(C)C([O-])=O IUGYQRQAERSCNH-UHFFFAOYSA-M 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DESC034140 | 1963-11-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1068058A true GB1068058A (en) | 1967-05-10 |
Family
ID=7433039
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB41756/64A Expired GB1068058A (en) | 1963-11-09 | 1964-10-13 | Process for the manufacture of í¸-16ª-methylsteroids and new í¸-16ª-methylsteroids |
Country Status (9)
| Country | Link |
|---|---|
| BE (1) | BE655494A (enrdf_load_stackoverflow) |
| BR (1) | BR6464017D0 (enrdf_load_stackoverflow) |
| DE (1) | DE1249270B (enrdf_load_stackoverflow) |
| DK (1) | DK118556B (enrdf_load_stackoverflow) |
| FR (1) | FR4556M (enrdf_load_stackoverflow) |
| GB (1) | GB1068058A (enrdf_load_stackoverflow) |
| NL (1) | NL155266B (enrdf_load_stackoverflow) |
| NO (1) | NO125050B (enrdf_load_stackoverflow) |
| SE (1) | SE324765B (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2596007A4 (en) * | 2010-07-20 | 2014-07-30 | Taro Pharma Ind | PROCESS FOR THE PREPARATION OF 17-DEOXY-CORTICOSTEROIDS |
-
0
- BE BE655494D patent/BE655494A/xx unknown
- DE DENDAT1249270D patent/DE1249270B/de active Pending
-
1964
- 1964-09-15 NO NO15475964A patent/NO125050B/no unknown
- 1964-10-13 GB GB41756/64A patent/GB1068058A/en not_active Expired
- 1964-10-27 DK DK529264A patent/DK118556B/da unknown
- 1964-11-02 NL NL646412708A patent/NL155266B/xx not_active IP Right Cessation
- 1964-11-06 BR BR16401764A patent/BR6464017D0/pt unknown
- 1964-11-09 SE SE1348664A patent/SE324765B/xx unknown
-
1965
- 1965-02-05 FR FR4502A patent/FR4556M/fr not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2596007A4 (en) * | 2010-07-20 | 2014-07-30 | Taro Pharma Ind | PROCESS FOR THE PREPARATION OF 17-DEOXY-CORTICOSTEROIDS |
| US10112970B2 (en) | 2010-07-20 | 2018-10-30 | Taro Pharmaceutical Industries Ltd. | Process for the preparation of 17-desoxy-corticosteroids |
Also Published As
| Publication number | Publication date |
|---|---|
| BR6464017D0 (pt) | 1973-07-26 |
| BE655494A (enrdf_load_stackoverflow) | |
| SE324765B (enrdf_load_stackoverflow) | 1970-06-15 |
| DK118556B (da) | 1970-09-07 |
| DE1249270B (de) | 1967-09-07 |
| NL155266B (nl) | 1977-12-15 |
| FR4556M (enrdf_load_stackoverflow) | 1966-11-02 |
| NO125050B (enrdf_load_stackoverflow) | 1972-07-10 |
| NL6412708A (enrdf_load_stackoverflow) | 1965-05-10 |
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