GB1066607A - Derivatives of benzamide - Google Patents
Derivatives of benzamideInfo
- Publication number
- GB1066607A GB1066607A GB8005/65A GB800565A GB1066607A GB 1066607 A GB1066607 A GB 1066607A GB 8005/65 A GB8005/65 A GB 8005/65A GB 800565 A GB800565 A GB 800565A GB 1066607 A GB1066607 A GB 1066607A
- Authority
- GB
- United Kingdom
- Prior art keywords
- methyl
- chloro
- benzamide
- ester
- anhydride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003936 benzamides Chemical class 0.000 title 1
- 150000008064 anhydrides Chemical class 0.000 abstract 3
- VXPJBOAGWKLNQL-UHFFFAOYSA-N 2-chloro-n,6-dimethylbenzamide Chemical compound CNC(=O)C1=C(C)C=CC=C1Cl VXPJBOAGWKLNQL-UHFFFAOYSA-N 0.000 abstract 2
- BAVYZALUXZFZLV-UHFFFAOYSA-N Methylamine Chemical compound NC BAVYZALUXZFZLV-UHFFFAOYSA-N 0.000 abstract 2
- CEFMMQYDPGCYMG-UHFFFAOYSA-N 2-chloro-6-methylbenzoic acid Chemical compound CC1=CC=CC(Cl)=C1C(O)=O CEFMMQYDPGCYMG-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000003874 central nervous system depressant Substances 0.000 abstract 1
- -1 cyano-methyl Chemical group 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
-
- E—FIXED CONSTRUCTIONS
- E04—BUILDING
- E04C—STRUCTURAL ELEMENTS; BUILDING MATERIALS
- E04C5/00—Reinforcing elements, e.g. for concrete; Auxiliary elements therefor
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Architecture (AREA)
- Civil Engineering (AREA)
- Structural Engineering (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
N - Methyl - 2 - chloro - 6 - methylbenzamide is prepared by reacting methylamine or its salts with a functionally reactive derivative (e.g. the halide, ester such as the cyano-methyl ester, anhydride, or mixed anhydride such as the mixed anhydride with p-toluenesulphonic acid) of 2-chloro-6-methylbenzoic acid. Therapeutic compositions in unit dosage form, which can be administered orally and which have a central nervous system depressant activity, contain N-methyl-2-chloro-6-methyl-benzamide as active ingredient.
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8005/65A GB1066607A (en) | 1965-02-24 | 1965-02-24 | Derivatives of benzamide |
| ES0323394A ES323394A1 (en) | 1965-02-24 | 1966-02-22 | A method for producing the N-methyl-2-chloro-6-methyl-benzamide compound. (Machine-translation by Google Translate, not legally binding) |
| LU50508A LU50508A1 (en) | 1965-02-24 | 1966-02-22 | |
| BE676969D BE676969A (en) | 1965-02-24 | 1966-02-24 | |
| BR17734866A BR6677348D0 (en) | 1965-02-24 | 1966-02-24 | PROCESS FOR THE PREPARATION OF A NEW PHARMACEUTICAL COMPOUND |
| NL6602437A NL6602437A (en) | 1965-02-24 | 1966-02-24 | |
| FR62248A FR6708M (en) | 1965-02-24 | 1966-05-20 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8005/65A GB1066607A (en) | 1965-02-24 | 1965-02-24 | Derivatives of benzamide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1066607A true GB1066607A (en) | 1967-04-26 |
Family
ID=9843958
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB8005/65A Expired GB1066607A (en) | 1965-02-24 | 1965-02-24 | Derivatives of benzamide |
Country Status (7)
| Country | Link |
|---|---|
| BE (1) | BE676969A (en) |
| BR (1) | BR6677348D0 (en) |
| ES (1) | ES323394A1 (en) |
| FR (1) | FR6708M (en) |
| GB (1) | GB1066607A (en) |
| LU (1) | LU50508A1 (en) |
| NL (1) | NL6602437A (en) |
-
1965
- 1965-02-24 GB GB8005/65A patent/GB1066607A/en not_active Expired
-
1966
- 1966-02-22 ES ES0323394A patent/ES323394A1/en not_active Expired
- 1966-02-22 LU LU50508A patent/LU50508A1/xx unknown
- 1966-02-24 BR BR17734866A patent/BR6677348D0/en unknown
- 1966-02-24 BE BE676969D patent/BE676969A/xx unknown
- 1966-02-24 NL NL6602437A patent/NL6602437A/xx unknown
- 1966-05-20 FR FR62248A patent/FR6708M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NL6602437A (en) | 1966-08-25 |
| BE676969A (en) | 1966-07-18 |
| ES323394A1 (en) | 1967-01-01 |
| LU50508A1 (en) | 1966-04-22 |
| BR6677348D0 (en) | 1973-09-18 |
| FR6708M (en) | 1969-02-17 |
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