GB1065124A - Phenyl-acetamido-propanediol derivatives - Google Patents
Phenyl-acetamido-propanediol derivativesInfo
- Publication number
- GB1065124A GB1065124A GB12569/65A GB1256965A GB1065124A GB 1065124 A GB1065124 A GB 1065124A GB 12569/65 A GB12569/65 A GB 12569/65A GB 1256965 A GB1256965 A GB 1256965A GB 1065124 A GB1065124 A GB 1065124A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acetamido
- formula
- phenyl
- threo
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- SKNPZPYDNYIAKP-UHFFFAOYSA-N N-(1,1-dihydroxy-2-phenylpropyl)acetamide Chemical class C1(=CC=CC=C1)C(C(O)(O)NC(C)=O)C SKNPZPYDNYIAKP-UHFFFAOYSA-N 0.000 title 1
- -1 alphaiminobenzyl-phenyl Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000007062 hydrolysis Effects 0.000 abstract 2
- 238000006460 hydrolysis reaction Methods 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C247/00—Compounds containing azido groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/40—Radicals substituted by oxygen atoms
- C07D307/42—Singly bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/40—Radicals substituted by oxygen atoms
- C07D307/46—Doubly bound oxygen atoms, or two oxygen atoms singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US231027A US3183265A (en) | 1962-10-16 | 1962-10-16 | Acylphenylacylamido-1, 3-propanediols and preparation therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1065124A true GB1065124A (en) | 1967-04-12 |
Family
ID=22867493
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB12569/65A Expired GB1065124A (en) | 1962-10-16 | 1963-10-11 | Phenyl-acetamido-propanediol derivatives |
| GB40165/63A Expired GB1065123A (en) | 1962-10-16 | 1963-10-11 | Acylphenyl-amino-1,3-propanediols and preparation thereof |
| GB4016/66A Expired GB1065125A (en) | 1962-10-16 | 1963-10-11 | Dichloroacetamido propanediol derivatives |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB40165/63A Expired GB1065123A (en) | 1962-10-16 | 1963-10-11 | Acylphenyl-amino-1,3-propanediols and preparation thereof |
| GB4016/66A Expired GB1065125A (en) | 1962-10-16 | 1963-10-11 | Dichloroacetamido propanediol derivatives |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US3183265A (enExample) |
| BE (1) | BE638755A (enExample) |
| BR (1) | BR6353747D0 (enExample) |
| CH (3) | CH437354A (enExample) |
| DE (1) | DE1518439A1 (enExample) |
| DK (1) | DK115265B (enExample) |
| ES (1) | ES292465A1 (enExample) |
| FR (1) | FR3897M (enExample) |
| GB (3) | GB1065124A (enExample) |
| SE (3) | SE301470B (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0308289A (pt) | 2002-03-08 | 2005-01-11 | Schering Plough Ltd | Antibióticos do tipo florfenicol |
| US8119667B2 (en) | 2005-12-29 | 2012-02-21 | Schering-Plough Animal Health Corporation | Carbonates of fenicol antibiotics |
| US8084643B2 (en) | 2006-12-13 | 2011-12-27 | Intervet Inc. | Water-soluble prodrugs of florfenicol and its analogs |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2597248A (en) * | 1948-08-06 | 1952-05-20 | Smith Kline French Lab | Nu-substituted amino-ethanols |
| US2600077A (en) * | 1948-10-05 | 1952-06-10 | Schenley Lab Inc | Thiosemicarbazones |
| US2568571A (en) * | 1950-09-23 | 1951-09-18 | Parke Davis & Co | Haloacetylamidophenyl-halo-acetamidopropandiol |
| US2721207A (en) * | 1952-11-01 | 1955-10-18 | Parke Davis & Co | Process for the production of amino diols and intermediate products utilized in said process |
| US2921080A (en) * | 1956-11-21 | 1960-01-12 | Sterling Drug Inc | Process for making 5-cyano-2-allyl-pyrrolidines and products therefrom |
-
0
- BE BE638755D patent/BE638755A/xx unknown
-
1962
- 1962-10-16 US US231027A patent/US3183265A/en not_active Expired - Lifetime
-
1963
- 1963-10-11 GB GB12569/65A patent/GB1065124A/en not_active Expired
- 1963-10-11 GB GB40165/63A patent/GB1065123A/en not_active Expired
- 1963-10-11 GB GB4016/66A patent/GB1065125A/en not_active Expired
- 1963-10-14 ES ES292465A patent/ES292465A1/es not_active Expired
- 1963-10-14 FR FR950558A patent/FR3897M/fr not_active Expired
- 1963-10-15 CH CH1262963A patent/CH437354A/de unknown
- 1963-10-15 DK DK485763AA patent/DK115265B/da unknown
- 1963-10-15 CH CH539267A patent/CH460812A/de unknown
- 1963-10-15 DE DE19631518439 patent/DE1518439A1/de active Granted
- 1963-10-15 CH CH539167A patent/CH455838A/de unknown
- 1963-10-16 SE SE11347/63A patent/SE301470B/xx unknown
- 1963-10-16 BR BR153747/63A patent/BR6353747D0/pt unknown
-
1965
- 1965-04-01 SE SE420965A patent/SE315876B/xx unknown
- 1965-07-27 SE SE9857/65A patent/SE322237B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SE301470B (enExample) | 1968-06-10 |
| SE315876B (enExample) | 1969-10-13 |
| GB1065123A (en) | 1967-04-12 |
| GB1065125A (en) | 1967-04-12 |
| DK115265B (da) | 1969-09-22 |
| CH437354A (de) | 1967-06-15 |
| CH460812A (de) | 1968-08-15 |
| ES292465A1 (es) | 1964-03-01 |
| BE638755A (enExample) | |
| CH455838A (de) | 1968-05-15 |
| FR3897M (enExample) | 1966-02-07 |
| SE322237B (enExample) | 1970-04-06 |
| BR6353747D0 (pt) | 1973-07-12 |
| US3183265A (en) | 1965-05-11 |
| DE1518439A1 (de) | 1972-03-09 |
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