GB1060428A - Process for the manufacture of 5'-purine nucleotides by a fermentation method - Google Patents

Process for the manufacture of 5'-purine nucleotides by a fermentation method

Info

Publication number
GB1060428A
GB1060428A GB1312464A GB1312464A GB1060428A GB 1060428 A GB1060428 A GB 1060428A GB 1312464 A GB1312464 A GB 1312464A GB 1312464 A GB1312464 A GB 1312464A GB 1060428 A GB1060428 A GB 1060428A
Authority
GB
United Kingdom
Prior art keywords
thiamine
extract
purine nucleotides
coenzyme
micro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1312464A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Publication of GB1060428A publication Critical patent/GB1060428A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/32—Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins

Landscapes

  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Seasonings (AREA)

Abstract

51-Purine nucleotides are prepared from purine bases or nucleosides by cultivating a micro-organism belonging to Brevibacterium ammoniagenes in a medium containing (1) pantothenic acid or other substance convertible into coenzyme A and (2) thiamine or other substance convertible into thiamine pyrophosphate, or natural substances containing such compounds. In place of pantothenic acid itself there may be used calcium pantothenate, b -alamine, pantethine, coenzyme A, meat extract, liver extract, rice bran, molasses or fish solubles, and as sources of thiamine there may be used rice husk and bran, yeast extract or liver extract. Adenine or guanine requiring mutants of the micro-organism may be used, these substances then being inluded in the medium.
GB1312464A 1963-04-10 1964-03-31 Process for the manufacture of 5'-purine nucleotides by a fermentation method Expired GB1060428A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP1761563 1963-04-10
JP4784163 1963-09-10

Publications (1)

Publication Number Publication Date
GB1060428A true GB1060428A (en) 1967-03-01

Family

ID=26354167

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1312464A Expired GB1060428A (en) 1963-04-10 1964-03-31 Process for the manufacture of 5'-purine nucleotides by a fermentation method

Country Status (10)

Country Link
AT (1) AT271738B (en)
BE (1) BE646342A (en)
CH (1) CH454881A (en)
DE (2) DE1695345B2 (en)
DK (1) DK105061C (en)
ES (1) ES298480A1 (en)
GB (1) GB1060428A (en)
NL (1) NL6403828A (en)
NO (1) NO120830B (en)
SE (1) SE316184B (en)

Also Published As

Publication number Publication date
NO120830B (en) 1970-12-14
DE1695345B2 (en) 1977-05-18
BE646342A (en) 1964-07-31
ES298480A1 (en) 1964-09-01
DE1695345A1 (en) 1972-04-20
CH454881A (en) 1968-04-30
AT271738B (en) 1969-06-10
NL6403828A (en) 1964-10-12
DK105061C (en) 1966-08-15
DE1445977A1 (en) 1969-03-06
SE316184B (en) 1969-10-20

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