GB1331933A - Antiviral ribonucleic acids - Google Patents
Antiviral ribonucleic acidsInfo
- Publication number
- GB1331933A GB1331933A GB1331933DA GB1331933A GB 1331933 A GB1331933 A GB 1331933A GB 1331933D A GB1331933D A GB 1331933DA GB 1331933 A GB1331933 A GB 1331933A
- Authority
- GB
- United Kingdom
- Prior art keywords
- particles
- virus
- antiviral
- ribonucleic acids
- ribonucleic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24123—Virus like particles [VLP]
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
1331933 Antiviral ribonucleic acids GLAXO LABORATORIES Ltd 13 Nov 1970 [17 Nov 1969] 56169/69 Heading C3H [Also in Division A5] A process for the production of one or both of the antiviral ribonucleic acids I and II from P. chrysogenum having the characteristics: ribonucleic acid IS 20,w (as herein defined) = 11À7 to 12À3 Base analysis: Guanine 25À0% Œ 1À0 Adenine 25À0% Œ 1À0. Cytosine 25À0% Œ 1À0. Uracil 25À0% Œ 1À0. Ribonucleic acid IIS 20,w (as herein defined) = 6-7 to 7À3 Base analysis: Guanine 18À0% Œ 1À0. Adenine 32À0% Œ 1À0. Cytosine 18À0% Œ 1À0. Uracil 32À0% Œ 1À0. Said process comprising the steps of (a) culturing a strain of P. chrysogenum, preferably ATCC 10,002, 10,003, 11,707, 13,799 or a mutant thereof in or on a nutrient medium therefor whereby virus-like particles as herein defined proliferate therein; (b) rupture of the cells of the micro-organism without removing the coating of the virus-like particles, and then removal of cell debris from the virus-like particles; (c) partial or complete separation of the viruslike particles from free nucleic acids and other dissolved materials; (d) decoating the virus-like particles; and (e) fractionation whereby the desired antiviral double-stranded ribonucleic acids I and II are isolated and unwanted material is rejected. Pharmaceutical compositions may be prepared from the products.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB5616969 | 1969-11-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1331933A true GB1331933A (en) | 1973-09-26 |
Family
ID=10475915
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1331933D Expired GB1331933A (en) | 1969-11-17 | 1969-11-17 | Antiviral ribonucleic acids |
Country Status (5)
Country | Link |
---|---|
BE (1) | BE758977A (en) |
DE (1) | DE2056294A1 (en) |
FR (1) | FR2073366B1 (en) |
GB (1) | GB1331933A (en) |
NL (1) | NL7016747A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0063657A1 (en) * | 1981-04-29 | 1982-11-03 | Merck & Co. Inc. | Topical application of interferon inducers |
US4908318A (en) * | 1987-09-04 | 1990-03-13 | Integrated Genetics, Inc. | Nucleic acid extraction methods |
US5057426A (en) * | 1986-11-22 | 1991-10-15 | Diagen Institut Fur Molekular-Biologische, Diagnostik Gmbh | Method for separating long-chain nucleic acids |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0039325A1 (en) * | 1979-10-19 | 1981-11-11 | ROMANO, Amalia | Medicine for the treatment of viral infections of the eye and other organs |
FR2550707B1 (en) * | 1983-08-17 | 1986-02-28 | Lipha | IMMUNOMODULATOR OF BIOLOGICAL MEDICINE AND PROCESS FOR PREPARING THE SAME |
DE3833925A1 (en) * | 1988-03-11 | 1989-09-21 | Inst Angewandte Biotechnologie | PROCESS AND MANUFACTURE OF VIRUS AND VIRAL ANTIGEN AND DEVICE THEREFOR |
-
0
- BE BE758977D patent/BE758977A/en unknown
-
1969
- 1969-11-17 GB GB1331933D patent/GB1331933A/en not_active Expired
-
1970
- 1970-11-16 DE DE19702056294 patent/DE2056294A1/en active Pending
- 1970-11-16 FR FR7041032A patent/FR2073366B1/fr not_active Expired
- 1970-11-16 NL NL7016747A patent/NL7016747A/xx unknown
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0063657A1 (en) * | 1981-04-29 | 1982-11-03 | Merck & Co. Inc. | Topical application of interferon inducers |
US5057426A (en) * | 1986-11-22 | 1991-10-15 | Diagen Institut Fur Molekular-Biologische, Diagnostik Gmbh | Method for separating long-chain nucleic acids |
US4908318A (en) * | 1987-09-04 | 1990-03-13 | Integrated Genetics, Inc. | Nucleic acid extraction methods |
Also Published As
Publication number | Publication date |
---|---|
BE758977A (en) | 1971-05-17 |
FR2073366A1 (en) | 1971-10-01 |
FR2073366B1 (en) | 1975-08-01 |
DE2056294A1 (en) | 1971-07-15 |
NL7016747A (en) | 1971-05-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PLNP | Patent lapsed through nonpayment of renewal fees |