GB1059578A - A vitamin preparation in beadlet form - Google Patents

A vitamin preparation in beadlet form

Info

Publication number
GB1059578A
GB1059578A GB38350/65A GB3835065A GB1059578A GB 1059578 A GB1059578 A GB 1059578A GB 38350/65 A GB38350/65 A GB 38350/65A GB 3835065 A GB3835065 A GB 3835065A GB 1059578 A GB1059578 A GB 1059578A
Authority
GB
United Kingdom
Prior art keywords
vitamin
ascorbic acid
mixture
tocopherol
sorbitol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB38350/65A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of GB1059578A publication Critical patent/GB1059578A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
    • A23C9/158—Milk preparations; Milk powder or milk powder preparations containing additives containing vitamins or antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems

Abstract

A modified gelatine is prepared by heating a mixture of gelatine and either ascorbic acid, a mixture of ascorbic acid and citric acid or a mixture of citric acid and sorbose in the presence of sorbitol. The term "ascorbic acid" includes iso-ascorbic acid. Either type A or B gelatine having a bloom within the range 30-100 may be used.ALSO:Milk is fortified by the addition of vitamin beadlets comprising a fat-soluble vitamin-containing material, and in cases where said material is other than a -tocopherol, a -tocopherol, and a modified gelatin. The latter is prepared by heating a mixture of gelatin and either ascorbic acid, a mixture of ascorbic acid and citric acid or a mixture of citric acid and sorbose in the presence of sorbitol. The term "ascorbic acid" also includes iso-ascorbic acid. The vitamin beadlets may optionally contain antioxidants e.g. butylated hydroxyanisole, butylated hydroxytoluene, platicizers e.g. sorbitol or corn syrup, buffers e.g. sodium citrate or colouring agents. The vitamin-containing material may be any material which contains vitamins A, D, E or K e.g. vitamin A acetate or palmitate. The vitamin beadlets may be initially dispersed in a liquid vehicle to form a concentrate which is subsequently added to the milk.ALSO:Vitamin compositions in beadlet form comprise a fat-soluble vitamin-containing material, and (incases where said material is other than a -tocopherol) a -tocopherol, and modified gelatin, optionally with antioxidants e.g. butylated hydroxyanisole, butylated hydroxytoluene, plasticisers e.g. sorbitol or corn syrup, buffers e.g. sodium citrate or colouring agents. The modified gelatin is prepared by heating a mixture of gelatin and either ascorbic acid, a mixture of ascorbic acid and citric acid or a mixture of citric acid and sorbose in the presence of sorbitol. The term "ascorbic acid" also includes iso-ascorbic acid. In a preferred method of manufacturing the vitamin compositions, an oil phase consisting of the vitamin-containing material, or (in cases where said material is other than a -tocopherol) a mixture thereof with a -tocopherol and optionally an antioxidant is emulsified with an aqueous solution containing the modified gelatin. The emulsion may be converted into beadlets by passing the emulsion through a revolving spray head and introducing the droplets into a suspension of collecting powder in air. The collecting powder may be a free-flowing starch ester, resistant to water-wetting, known as "Dry-Flo". Specified fat-soluble vitamin-containing materials include vitamin A acetate and palmitate.
GB38350/65A 1964-09-09 1965-09-08 A vitamin preparation in beadlet form Expired GB1059578A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US39527864A 1964-09-09 1964-09-09

Publications (1)

Publication Number Publication Date
GB1059578A true GB1059578A (en) 1967-02-22

Family

ID=23562386

Family Applications (1)

Application Number Title Priority Date Filing Date
GB38350/65A Expired GB1059578A (en) 1964-09-09 1965-09-08 A vitamin preparation in beadlet form

Country Status (8)

Country Link
BE (1) BE669166A (en)
CH (1) CH477824A (en)
DE (1) DE1467943A1 (en)
ES (1) ES317239A1 (en)
FR (1) FR4653M (en)
GB (1) GB1059578A (en)
IL (1) IL24216A (en)
NL (1) NL6511632A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3215086A1 (en) * 1981-04-29 1982-11-18 F. Hoffmann-La Roche & Co AG, 4002 Basel PHARMACEUTICAL PREPARATIONS

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3446899A (en) * 1968-01-25 1969-05-27 Hoffmann La Roche Vitamin compositions produced by direct compression
US6011016A (en) * 1997-10-23 2000-01-04 Basf Corporation Fat soluble vitamin emulsions suitable for spraying onto foodstuffs

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3215086A1 (en) * 1981-04-29 1982-11-18 F. Hoffmann-La Roche & Co AG, 4002 Basel PHARMACEUTICAL PREPARATIONS

Also Published As

Publication number Publication date
CH477824A (en) 1969-09-15
NL6511632A (en) 1966-03-10
FR4653M (en) 1966-12-05
DE1467943A1 (en) 1969-01-30
IL24216A (en) 1968-11-27
BE669166A (en) 1966-03-03
ES317239A1 (en) 1966-03-16

Similar Documents

Publication Publication Date Title
US3102078A (en) Water-dispersible vitamin preparations
JP2542697B2 (en) Powder preparation
RU2008120696A (en) MIXTURE FOR CHILDREN'S NUTRITION (OPTIONS), METHOD FOR REDUCING THE RISK OF DEVELOPMENT OF RETROLETO FIBROPLASIA (OPTIONS) AND METHOD FOR MAINTAINING HEALTHY RETAIL AND VISION DEVELOPMENT (OPTIONS)
KR900013952A (en) Ibuprofen composition for oral administration
GB8318396D0 (en) Corticoid-containing preparations
JPH04211334A (en) Coated vitamin c preparation for feed, production thereof and use thereof
CN105639647B (en) A kind of vitamin, carotenoid pulvis and its preparation method and application
US3558323A (en) Vitamin-containing composition in beadlet form
US3869539A (en) Preparations containing fat-soluble vitamins in dry, particulate, free-flowing form dispersible in cold water and method of producing such preparations
CN110522738A (en) A kind of Lutein ester microcapsule preparation and its preparation method and application
GB1026493A (en) Dry,vitamin-active product and process for preparing same
JPS61126016A (en) Microcapsule containing unsaturated fatty acid
GB1059578A (en) A vitamin preparation in beadlet form
US3436459A (en) Fat soluble vitamin compositions
US3089823A (en) Aqueous vitamin a oil emulsion
GB490001A (en) Improvements in or relating to a vitamin product
ES343990A1 (en) A Process for the Preparation of Homogeneous Beadlets Incorporating Active Ingredients(s).
CA2220178C (en) Dry preparations containing microbially produced oil
US2940900A (en) Dry vitamine e composition
GB918168A (en) Improvements in feed supplements
US2519487A (en) Multivitamin preparation
US3749799A (en) Stable dry vitamin a preparations
Edwards Jr et al. Serum and egg cholesterol levels in mature hens as influenced by dietary protein and fat changes
US2318894A (en) Biologically active substance for controlling procreative metabolism
GB1315276A (en) Vitamin powders