GB1056291A - Improved process for preparing sodium warfarin - Google Patents

Improved process for preparing sodium warfarin

Info

Publication number
GB1056291A
GB1056291A GB115/64A GB11564A GB1056291A GB 1056291 A GB1056291 A GB 1056291A GB 115/64 A GB115/64 A GB 115/64A GB 11564 A GB11564 A GB 11564A GB 1056291 A GB1056291 A GB 1056291A
Authority
GB
United Kingdom
Prior art keywords
warfarin
sodium warfarin
improved process
sodium
ethanol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB115/64A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Frosst Canada and Co
Original Assignee
Charles E Frosst and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Charles E Frosst and Co filed Critical Charles E Frosst and Co
Publication of GB1056291A publication Critical patent/GB1056291A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/42—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4
    • C07D311/44—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3
    • C07D311/46—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3 unsubstituted in the carbocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB115/64A 1963-05-14 1964-01-01 Improved process for preparing sodium warfarin Expired GB1056291A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA875556 1963-05-14

Publications (1)

Publication Number Publication Date
GB1056291A true GB1056291A (en) 1967-01-25

Family

ID=4141722

Family Applications (1)

Application Number Title Priority Date Filing Date
GB115/64A Expired GB1056291A (en) 1963-05-14 1964-01-01 Improved process for preparing sodium warfarin

Country Status (3)

Country Link
BE (1) BE644186A (nl)
FR (1) FR1397213A (nl)
GB (1) GB1056291A (nl)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1089992A1 (en) * 1995-12-28 2001-04-11 Hoechst Celanese Corporation Syntheses based on 2-hydroxyacetophenone
US6673944B2 (en) * 2001-02-28 2004-01-06 Taro Pharmaceutical Industries, Ltd. Preparation of warfarin sodium from warfarin acid
WO2011145007A1 (en) * 2010-05-20 2011-11-24 Alembic Pharmaceuticals Limited A process for the preparation of amorphous warfarin sodium

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6512005B2 (en) 2001-02-28 2003-01-28 Taro Pharmaceutical Industries, Ltd. Process for synthesis of pure warfarin acid, warfarin alkali metal salts and corresponding clathrates
MXPA03007769A (es) * 2001-02-28 2005-07-01 Taro Pharmaceuticals Usa Inc Proceso para la purificacion de acido warfarin, sales de metal alcali de warfarin y clatratos correspondientes.
US6610862B2 (en) 2001-02-28 2003-08-26 Taro Pharmaceutical Industries Ltd. Preparation of warfarin sodium from warfarin sodium-2-propanol clathrate by solvent expulsion

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1089992A1 (en) * 1995-12-28 2001-04-11 Hoechst Celanese Corporation Syntheses based on 2-hydroxyacetophenone
EP1089992A4 (en) * 1995-12-28 2001-04-11 Hoechst Celanese Corp SYNTHESIS BASED ON 2-HYDROXY ACETOPHENONE
US6673944B2 (en) * 2001-02-28 2004-01-06 Taro Pharmaceutical Industries, Ltd. Preparation of warfarin sodium from warfarin acid
WO2011145007A1 (en) * 2010-05-20 2011-11-24 Alembic Pharmaceuticals Limited A process for the preparation of amorphous warfarin sodium

Also Published As

Publication number Publication date
FR1397213A (fr) 1965-04-30
BE644186A (nl) 1964-08-21

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