GB1049000A - Sulphur-containing androstane derivatives and process for their production - Google Patents
Sulphur-containing androstane derivatives and process for their productionInfo
- Publication number
- GB1049000A GB1049000A GB50671/63A GB5067163A GB1049000A GB 1049000 A GB1049000 A GB 1049000A GB 50671/63 A GB50671/63 A GB 50671/63A GB 5067163 A GB5067163 A GB 5067163A GB 1049000 A GB1049000 A GB 1049000A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hydrogen
- formula
- compounds
- atoms
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 title abstract 2
- 239000005864 Sulphur Substances 0.000 title 1
- 150000001440 androstane derivatives Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 3
- RWSOTUBLDIXVET-UHFFFAOYSA-N Dihydrogen sulfide Chemical compound S RWSOTUBLDIXVET-UHFFFAOYSA-N 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 230000001195 anabolic effect Effects 0.000 abstract 1
- 150000001443 androstenes Chemical class 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000006071 cream Substances 0.000 abstract 1
- 150000001991 dicarboxylic acids Chemical class 0.000 abstract 1
- 239000008298 dragée Substances 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 125000004185 ester group Chemical group 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 229910052744 lithium Inorganic materials 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000002763 monocarboxylic acids Chemical class 0.000 abstract 1
- 239000002674 ointment Substances 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 229920006395 saturated elastomer Chemical group 0.000 abstract 1
- 229930195734 saturated hydrocarbon Chemical group 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
- 229930195735 unsaturated hydrocarbon Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEM55244A DE1198356B (de) | 1962-12-24 | 1962-12-24 | Verfahren zur Herstellung von schwefelhaltigen Androstanderivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1049000A true GB1049000A (en) | 1966-11-23 |
Family
ID=7308245
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB50671/63A Expired GB1049000A (en) | 1962-12-24 | 1963-12-23 | Sulphur-containing androstane derivatives and process for their production |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US3164584A (cg-RX-API-DMAC7.html) |
| BE (1) | BE641674A (cg-RX-API-DMAC7.html) |
| CH (1) | CH447154A (cg-RX-API-DMAC7.html) |
| DE (1) | DE1198356B (cg-RX-API-DMAC7.html) |
| DK (1) | DK104733C (cg-RX-API-DMAC7.html) |
| FR (1) | FR3129M (cg-RX-API-DMAC7.html) |
| GB (1) | GB1049000A (cg-RX-API-DMAC7.html) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2260953A (en) * | 1939-11-29 | 1941-10-28 | Rebold Rudolph | Thiosteroid and process for producing the same |
-
0
- BE BE641674D patent/BE641674A/xx unknown
-
1962
- 1962-12-24 DE DEM55244A patent/DE1198356B/de active Pending
-
1963
- 1963-10-25 CH CH1311563A patent/CH447154A/de unknown
- 1963-11-25 FR FR954857A patent/FR3129M/fr active Active
- 1963-12-17 DK DK588763AA patent/DK104733C/da active
- 1963-12-23 GB GB50671/63A patent/GB1049000A/en not_active Expired
- 1963-12-24 US US333046A patent/US3164584A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CH447154A (de) | 1967-11-30 |
| BE641674A (cg-RX-API-DMAC7.html) | |
| DK104733C (da) | 1966-06-27 |
| US3164584A (en) | 1965-01-05 |
| DE1198356B (de) | 1965-08-12 |
| FR3129M (fr) | 1965-02-15 |
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