GB1039373A - Dibenzocycloheptene derivatives - Google Patents

Abstract

The invention comprises compounds of the formulae <FORM:1039373/C2/1> and <FORM:1039373/C2/2> wherein each of X and X1 is a hydrogen or halogen atom, or a C1- 5 alkyl, C1- 5 alkoxy, C2- 5 alkenyl, C1- 5 haloalkyl, phenyl, substituted phenyl, C1- 4 acyl, C1- 4 haloacyl, amino, C1- 5 alkylamino, di(C1- 5 alkyl)amino, C1- 4 acylamino, C1- 4 haloacylamino, C1- 5 alkylsulphonylamino, hydroxyl, C1- 5 haloalkoxy, cyano, carboxy, carbamoyl, C1- 5 alkyl carbamoyl, di(C1- 5 alkyl) carbamoyl, C1- 5 alkoxy carbonyl, mercapto, C1- 5 alkylmercapto, C1- 5 haloalkylmercapto, C1- 5 alkylsulphonyl, C1- 5 haloalkylsulphonyl, sulphamoyl or di(C1- 5 alkyl)sulphamoyl radical, and hal is a halogen atom; and wherein more than one substituent may be on each benzenoid ring; processes for their preparation comprising (a) reacting a compound of the formula <FORM:1039373/C2/3> or <FORM:1039373/C2/4> with a halogenating agent, or (b) reacting a compound of the formula <FORM:1039373/C2/5> or <FORM:1039373/C2/6> with a hydrogen halide; and a process for preparin compounds of the formula <FORM:1039373/C2/7> or <FORM:1039373/C2/8> or non-toxic, acid-addition salts thereof, wherein each of R and R1 represents a hydrogen atom or a C1- 5 alkyl, C2- 5 alkenyl, cycloalkyl, phenyl or benzyl radical or NRR1 represents a 1-piperidyl, 1-pyrrolidinyl, 4-morpholinyl or 1-(C1- 5 alkyl)-4-piperazinyl ring, by aminating a compound of the invention.