GB729891A - New 4,5-dihydro-1,3,4-oxadiazol-5-one derivatives - Google Patents

New 4,5-dihydro-1,3,4-oxadiazol-5-one derivatives

Info

Publication number
GB729891A
GB729891A GB27716/53A GB2771653A GB729891A GB 729891 A GB729891 A GB 729891A GB 27716/53 A GB27716/53 A GB 27716/53A GB 2771653 A GB2771653 A GB 2771653A GB 729891 A GB729891 A GB 729891A
Authority
GB
United Kingdom
Prior art keywords
oxadiazol
dihydro
derivatives
new
pyridyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB27716/53A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of GB729891A publication Critical patent/GB729891A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Abstract

The invention comprises compounds of the formula <FORM:0729891/IV (b)/1> wherein R is H or an alkyl radical. The compounds, which have anti-tubercular activity, are prepared by reacting an isonicotinic hydrazide or its salt in aqueous solution with phosgene, giving the hydrochloride from which the base may be liberated. The examples describe the preparation of 2-(41-pyridyl)-4,5-dihydro - 1,3,4 - oxadiazol - 5 - one and the (21-methyl-41-pyridyl) derivative.
GB27716/53A 1952-10-10 1953-10-08 New 4,5-dihydro-1,3,4-oxadiazol-5-one derivatives Expired GB729891A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE319063X 1952-10-10

Publications (1)

Publication Number Publication Date
GB729891A true GB729891A (en) 1955-05-11

Family

ID=6151479

Family Applications (1)

Application Number Title Priority Date Filing Date
GB27716/53A Expired GB729891A (en) 1952-10-10 1953-10-08 New 4,5-dihydro-1,3,4-oxadiazol-5-one derivatives

Country Status (3)

Country Link
CH (1) CH319063A (en)
FR (1) FR1160682A (en)
GB (1) GB729891A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD4118C1 (en) * 2010-09-02 2012-02-29 Институт Химии Академии Наук Молдовы 1,3,4-Oxadiazole compounds containing disubstituted thiourea, manifesting antituberculous properties
MD4125C1 (en) * 2010-09-17 2012-03-31 Inst De Chimie Al Academiei De Stiinte A Moldovei 1,3,4-Oxadiazole compounds with antituberculous properties containing monosubstituted thiourea

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD4118C1 (en) * 2010-09-02 2012-02-29 Институт Химии Академии Наук Молдовы 1,3,4-Oxadiazole compounds containing disubstituted thiourea, manifesting antituberculous properties
MD4125C1 (en) * 2010-09-17 2012-03-31 Inst De Chimie Al Academiei De Stiinte A Moldovei 1,3,4-Oxadiazole compounds with antituberculous properties containing monosubstituted thiourea

Also Published As

Publication number Publication date
CH319063A (en) 1957-01-31
FR1160682A (en) 1958-07-24

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