GB1018381A - A process for the manufacture of úú¾ú´quinoline derivatives - Google Patents
A process for the manufacture of úú¾ú´quinoline derivativesInfo
- Publication number
- GB1018381A GB1018381A GB8642/63A GB864263A GB1018381A GB 1018381 A GB1018381 A GB 1018381A GB 8642/63 A GB8642/63 A GB 8642/63A GB 864263 A GB864263 A GB 864263A GB 1018381 A GB1018381 A GB 1018381A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- formula
- acid
- alkoxy
- acid addition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 8
- 150000001875 compounds Chemical class 0.000 abstract 7
- 239000002253 acid Substances 0.000 abstract 5
- 125000003545 alkoxy group Chemical group 0.000 abstract 4
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 239000012458 free base Substances 0.000 abstract 3
- 241001465754 Metazoa Species 0.000 abstract 2
- 125000003739 carbamimidoyl group Chemical group C(N)(=N)* 0.000 abstract 2
- 208000015181 infectious disease Diseases 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- XZMCDFZZKTWFGF-UHFFFAOYSA-N Cyanamide Chemical compound NC#N XZMCDFZZKTWFGF-UHFFFAOYSA-N 0.000 abstract 1
- 208000001953 Hypotension Diseases 0.000 abstract 1
- 150000000994 L-ascorbates Chemical class 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 235000010323 ascorbic acid Nutrition 0.000 abstract 1
- 239000002585 base Substances 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 238000009877 rendering Methods 0.000 abstract 1
- 150000003873 salicylate salts Chemical class 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 150000003672 ureas Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17771962A | 1962-03-06 | 1962-03-06 | |
| US245426A US3157573A (en) | 1962-12-18 | 1962-12-18 | Antihypertensive 3, 4-dihydro-2(1h)-isoquinolinecarboxamidine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1018381A true GB1018381A (en) | 1966-01-26 |
Family
ID=26873576
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB8642/63A Expired GB1018381A (en) | 1962-03-06 | 1963-03-05 | A process for the manufacture of úú¾ú´quinoline derivatives |
Country Status (11)
-
1963
- 1963-02-22 CH CH231063A patent/CH433310A/de unknown
- 1963-02-25 DE DE19631695156 patent/DE1695156B1/de active Pending
- 1963-03-02 FR FR926620A patent/FR2425M/fr not_active Expired
- 1963-03-04 SE SE2338/63A patent/SE324567B/xx unknown
- 1963-03-05 DK DK100763AA patent/DK102917C/da active
- 1963-03-05 GB GB8642/63A patent/GB1018381A/en not_active Expired
- 1963-03-05 ES ES285739A patent/ES285739A1/es not_active Expired
- 1963-03-06 FI FI0434/63A patent/FI44232B/fi active
-
1965
- 1965-09-03 OA OA52178A patent/OA01814A/xx unknown
-
1966
- 1966-12-10 CY CY35666A patent/CY356A/xx unknown
-
1967
- 1967-12-31 MY MY196724A patent/MY6700024A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE1695156B1 (de) | 1972-05-31 |
| SE324567B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1970-06-08 |
| OA01814A (fr) | 1970-01-14 |
| ES285739A1 (es) | 1963-08-01 |
| DK102917C (da) | 1965-10-25 |
| FI44232B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1971-06-30 |
| CH433310A (de) | 1967-04-15 |
| CY356A (en) | 1966-12-10 |
| MY6700024A (en) | 1967-12-31 |
| FR2425M (fr) | 1964-03-23 |
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