GB1006588A - N-substituted-1-phenyl-2-aminopropanes - Google Patents
N-substituted-1-phenyl-2-aminopropanesInfo
- Publication number
- GB1006588A GB1006588A GB39753/62A GB3975362A GB1006588A GB 1006588 A GB1006588 A GB 1006588A GB 39753/62 A GB39753/62 A GB 39753/62A GB 3975362 A GB3975362 A GB 3975362A GB 1006588 A GB1006588 A GB 1006588A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- ethyl
- group
- compounds
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 N-substituted-1-phenyl-2-aminopropanes Chemical class 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 9
- 239000002253 acid Substances 0.000 abstract 6
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
- 150000001299 aldehydes Chemical class 0.000 abstract 4
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 3
- KWTSXDURSIMDCE-UHFFFAOYSA-N 1-phenylpropan-2-amine Chemical compound CC(N)CC1=CC=CC=C1 KWTSXDURSIMDCE-UHFFFAOYSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 abstract 2
- 238000009833 condensation Methods 0.000 abstract 2
- 230000005494 condensation Effects 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 238000010438 heat treatment Methods 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 231100000252 nontoxic Toxicity 0.000 abstract 2
- 230000003000 nontoxic effect Effects 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- HSFWRNGVRCDJHI-UHFFFAOYSA-N alpha-acetylene Natural products C#C HSFWRNGVRCDJHI-UHFFFAOYSA-N 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 210000004204 blood vessel Anatomy 0.000 abstract 1
- 125000001246 bromo group Chemical group Br* 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 150000001735 carboxylic acids Chemical class 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 230000000916 dilatatory effect Effects 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 125000002534 ethynyl group Chemical group [H]C#C* 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 238000006317 isomerization reaction Methods 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- QCCDLTOVEPVEJK-UHFFFAOYSA-N phenylacetone Chemical compound CC(=O)CC1=CC=CC=C1 QCCDLTOVEPVEJK-UHFFFAOYSA-N 0.000 abstract 1
- 239000006187 pill Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 230000002829 reductive effect Effects 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 239000006188 syrup Substances 0.000 abstract 1
- 235000020357 syrup Nutrition 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/02—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with only hydrogen, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/46—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid
- C07C57/50—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid containing condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
- C07D311/82—Xanthenes
- C07D311/90—Xanthenes with hydrocarbon radicals, substituted by amino radicals, directly attached in position 9
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/18—Fluorenes; Hydrogenated fluorenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Priority Applications (16)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BE638839D BE638839A (enrdf_load_stackoverflow) | 1962-10-19 | ||
NL299449D NL299449A (enrdf_load_stackoverflow) | 1962-10-19 | ||
NL133997D NL133997C (enrdf_load_stackoverflow) | 1962-10-19 | ||
GB39753/62A GB1006588A (en) | 1962-10-19 | 1962-10-19 | N-substituted-1-phenyl-2-aminopropanes |
US302707A US3359263A (en) | 1962-10-19 | 1963-08-16 | Nu-substituted-1-phenyl-2-aminopropanes |
FI2027/63A FI42543B (enrdf_load_stackoverflow) | 1962-10-19 | 1963-10-17 | |
DK493363AA DK109925C (da) | 1962-10-19 | 1963-10-18 | Fremgangsmåde til fremstilling af N-substituerede 1-phenyl-2-aminopropaner eller syreadditionssalte heraf. |
BR153836/63A BR6353836D0 (pt) | 1962-10-19 | 1963-10-18 | Processo de preparacao de n-substituidos-1-fenil-2-amino propanos |
FR951049A FR1450391A (fr) | 1962-10-19 | 1963-10-18 | 1-phényl-2-aminopropanes n-substitués et leur procédé de préparation |
CH1280863A CH455754A (de) | 1962-10-19 | 1963-10-18 | Verfahren zur Herstellung von N-substituierten 1-Phenyl-2-aminopropanen |
DEN23907A DE1214688B (de) | 1962-10-19 | 1963-10-18 | Verfahren zur Herstellung von N-substituierten 1-Phenyl-2-aminopropanen sowie deren nicht-toxischen Saeureadditionssalzen |
ES0292867A ES292867A1 (es) | 1962-10-19 | 1963-10-18 | Procedimiento para la preparaciën de i-fenil-2-aminopropanos n-sustituidos |
SE11503/63A SE313301B (enrdf_load_stackoverflow) | 1962-10-19 | 1963-10-19 | |
FR960756A FR3974M (enrdf_load_stackoverflow) | 1962-10-19 | 1964-01-17 | |
DK90066AA DK111174B (da) | 1962-10-19 | 1966-02-21 | Fremgangsmåde til fremstilling af N-substituerede l-phenyl-2-aminopropaner eller syreadditionssalte heraf. |
FI2232/69A FI44241B (enrdf_load_stackoverflow) | 1962-10-19 | 1969-07-28 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB39753/62A GB1006588A (en) | 1962-10-19 | 1962-10-19 | N-substituted-1-phenyl-2-aminopropanes |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1006588A true GB1006588A (en) | 1965-10-06 |
Family
ID=10411293
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB39753/62A Expired GB1006588A (en) | 1962-10-19 | 1962-10-19 | N-substituted-1-phenyl-2-aminopropanes |
Country Status (12)
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0035903A1 (en) * | 1980-03-11 | 1981-09-16 | American Home Products Corporation | Dibenzocycloheptenylidenes and their use in pharmaceutical compositions |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR145F (enrdf_load_stackoverflow) * | 1964-06-01 | |||
US3452009A (en) * | 1965-05-03 | 1969-06-24 | Merck & Co Inc | 2,3-epoxypropylidene derivative of 5h-dibenzo(a,d)-10,11-dihydrocycloheptenes |
FR2499556B1 (enrdf_load_stackoverflow) * | 1981-02-10 | 1983-03-25 | Cird | |
WO1997046549A1 (en) * | 1996-06-05 | 1997-12-11 | Novartis Ag | Anti-neurodegeneratively effective xanthene derivatives |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2676971A (en) * | 1951-04-21 | 1954-04-27 | Searle & Co | Quaternary ammonium derivatives of aminoalkylxanthenes and aminoalkylthiaxanthenes |
US3073847A (en) * | 1959-02-12 | 1963-01-15 | Hoffmann La Roche | 9-(3-amino-1-propynyl) derivatives of 9-xanthenols and 9-thioxanthenols and a process for their preparation |
NL274885A (enrdf_load_stackoverflow) * | 1960-09-16 | |||
NL290533A (enrdf_load_stackoverflow) * | 1962-03-23 | |||
US3258459A (en) * | 1962-08-30 | 1966-06-28 | Squibb & Sons Inc | Method for the preparation of n-monosubstituted-secondary aminoalkyl derivatives of polycyclic compounds |
US3264342A (en) * | 1963-05-24 | 1966-08-02 | Geigy Chem Corp | Derivatives of 5h-dibenzo[a, d] cycloheptene |
US3258488A (en) * | 1963-08-12 | 1966-06-28 | Colgate Palmolive Co | Dibenzo[a, d]cycloheptene derivatives |
-
0
- NL NL299449D patent/NL299449A/xx unknown
- BE BE638839D patent/BE638839A/xx unknown
- NL NL133997D patent/NL133997C/xx active
-
1962
- 1962-10-19 GB GB39753/62A patent/GB1006588A/en not_active Expired
-
1963
- 1963-08-16 US US302707A patent/US3359263A/en not_active Expired - Lifetime
- 1963-10-17 FI FI2027/63A patent/FI42543B/fi active
- 1963-10-18 DK DK493363AA patent/DK109925C/da active
- 1963-10-18 CH CH1280863A patent/CH455754A/de unknown
- 1963-10-18 FR FR951049A patent/FR1450391A/fr not_active Expired
- 1963-10-18 BR BR153836/63A patent/BR6353836D0/pt unknown
- 1963-10-18 ES ES0292867A patent/ES292867A1/es not_active Expired
- 1963-10-18 DE DEN23907A patent/DE1214688B/de active Pending
- 1963-10-19 SE SE11503/63A patent/SE313301B/xx unknown
-
1964
- 1964-01-17 FR FR960756A patent/FR3974M/fr not_active Expired
-
1966
- 1966-02-21 DK DK90066AA patent/DK111174B/da unknown
-
1969
- 1969-07-28 FI FI2232/69A patent/FI44241B/fi active
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0035903A1 (en) * | 1980-03-11 | 1981-09-16 | American Home Products Corporation | Dibenzocycloheptenylidenes and their use in pharmaceutical compositions |
Also Published As
Publication number | Publication date |
---|---|
BE638839A (enrdf_load_stackoverflow) | |
NL133997C (enrdf_load_stackoverflow) | |
DE1214688B (de) | 1966-04-21 |
DK111174B (da) | 1968-06-24 |
FI42543B (enrdf_load_stackoverflow) | 1970-06-01 |
US3359263A (en) | 1967-12-19 |
FI44241B (enrdf_load_stackoverflow) | 1971-06-30 |
ES292867A1 (es) | 1964-04-01 |
FR1450391A (fr) | 1966-06-24 |
FR3974M (enrdf_load_stackoverflow) | 1966-03-07 |
NL299449A (enrdf_load_stackoverflow) | |
BR6353836D0 (pt) | 1973-07-12 |
CH455754A (de) | 1968-05-15 |
DK109925C (da) | 1968-08-05 |
SE313301B (enrdf_load_stackoverflow) | 1969-08-11 |
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