GB1002346A - Aminoalkyl esters of 3ª‰-hydroxypregn-5-en-20-one - Google Patents

Aminoalkyl esters of 3ª‰-hydroxypregn-5-en-20-one

Info

Publication number
GB1002346A
GB1002346A GB4003363A GB4003363A GB1002346A GB 1002346 A GB1002346 A GB 1002346A GB 4003363 A GB4003363 A GB 4003363A GB 4003363 A GB4003363 A GB 4003363A GB 1002346 A GB1002346 A GB 1002346A
Authority
GB
United Kingdom
Prior art keywords
radical
general formula
alk
carbon atoms
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4003363A
Inventor
Charles Wheeler Marshall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Priority to GB4003363A priority Critical patent/GB1002346A/en
Publication of GB1002346A publication Critical patent/GB1002346A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives

Abstract

The invention comprises compounds of the general formula <FORM:1002346/C2/1> wherein Alk is an alkylene radical containing from 1-5 carbon atoms and Z is a morpholino or 4-alkylpiperazino radical, or a radical of the general formula <FORM:1002346/C2/2> in which one of the R1 and R11 is an o -hydroxyalkyl or benzyl radical, and the other is an alkyl radical, and wherein the alkyl and hydroxyalkyl groups encompassed by Z contain from 1-6 carbon atoms and non-toxic addition salts thereof, and a process for the preparation thereof by contacting a compound of the formula <FORM:1002346/C2/3> wherein Alk is as defined above, with an amine of the general formula Z-H. The reaction may be effected in the presence of an alkali metal iodide. Pharmaceutical compositions having anti-convulsant and anti-psychotic activities comprise the above compounds and a pharmaceutical carrier.
GB4003363A 1963-10-10 1963-10-10 Aminoalkyl esters of 3ª‰-hydroxypregn-5-en-20-one Expired GB1002346A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB4003363A GB1002346A (en) 1963-10-10 1963-10-10 Aminoalkyl esters of 3ª‰-hydroxypregn-5-en-20-one

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4003363A GB1002346A (en) 1963-10-10 1963-10-10 Aminoalkyl esters of 3ª‰-hydroxypregn-5-en-20-one

Publications (1)

Publication Number Publication Date
GB1002346A true GB1002346A (en) 1965-08-25

Family

ID=10412829

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4003363A Expired GB1002346A (en) 1963-10-10 1963-10-10 Aminoalkyl esters of 3ª‰-hydroxypregn-5-en-20-one

Country Status (1)

Country Link
GB (1) GB1002346A (en)

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