GB1001689A - Process for the production of a rabies vaccine - Google Patents
Process for the production of a rabies vaccineInfo
- Publication number
- GB1001689A GB1001689A GB27896/63A GB2789663A GB1001689A GB 1001689 A GB1001689 A GB 1001689A GB 27896/63 A GB27896/63 A GB 27896/63A GB 2789663 A GB2789663 A GB 2789663A GB 1001689 A GB1001689 A GB 1001689A
- Authority
- GB
- United Kingdom
- Prior art keywords
- medium
- virus
- passages
- days
- culture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 229960003127 rabies vaccine Drugs 0.000 title 1
- 239000002609 medium Substances 0.000 abstract 8
- 241000700605 Viruses Species 0.000 abstract 5
- 241000711798 Rabies lyssavirus Species 0.000 abstract 4
- 210000003837 chick embryo Anatomy 0.000 abstract 4
- 239000001963 growth medium Substances 0.000 abstract 4
- 238000012423 maintenance Methods 0.000 abstract 4
- 238000003306 harvesting Methods 0.000 abstract 3
- 239000007788 liquid Substances 0.000 abstract 3
- 238000010790 dilution Methods 0.000 abstract 2
- 239000012895 dilution Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000000243 solution Substances 0.000 abstract 2
- 229960005486 vaccine Drugs 0.000 abstract 2
- 102000004407 Lactalbumin Human genes 0.000 abstract 1
- 108090000942 Lactalbumin Proteins 0.000 abstract 1
- 150000001447 alkali salts Chemical class 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 239000007640 basal medium Substances 0.000 abstract 1
- 108010079058 casein hydrolysate Proteins 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 235000013601 eggs Nutrition 0.000 abstract 1
- 239000000413 hydrolysate Substances 0.000 abstract 1
- 238000011081 inoculation Methods 0.000 abstract 1
- 230000003834 intracellular effect Effects 0.000 abstract 1
- 239000002504 physiological saline solution Substances 0.000 abstract 1
- 235000018102 proteins Nutrition 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 239000012266 salt solution Substances 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
- 239000006228 supernatant Substances 0.000 abstract 1
- 229940124974 vaccine stabilizer Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/205—Rhabdoviridae, e.g. rabies virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20111—Lyssavirus, e.g. rabies virus
- C12N2760/20134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US214854A US3255080A (en) | 1962-08-06 | 1962-08-06 | Live rabies virus vaccine and method for the production thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1001689A true GB1001689A (en) | 1965-08-18 |
Family
ID=22800666
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB27896/63A Expired GB1001689A (en) | 1962-08-06 | 1963-07-15 | Process for the production of a rabies vaccine |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US3255080A (en:Method) |
| CH (1) | CH455148A (en:Method) |
| DK (1) | DK105426C (en:Method) |
| FR (1) | FR3839M (en:Method) |
| GB (1) | GB1001689A (en:Method) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4021302A (en) * | 1966-02-18 | 1977-05-03 | Burroughs Wellcome & Co., Inc. | Cell cultures |
| US3674862A (en) * | 1970-04-02 | 1972-07-04 | Lilly Co Eli | Live attenuated rabies virus vaccine and process therefor |
| GB1596653A (en) * | 1977-01-26 | 1981-08-26 | Gist Brocades Nv | Vaccine |
| CH638985A5 (de) * | 1979-04-10 | 1983-10-31 | Schweiz Serum & Impfinst | Verfahren zur herstellung eines tollwutimpfstoffes und danach erhaltener impfstoff. |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2768114A (en) * | 1953-08-21 | 1956-10-23 | American Cyanamid Co | Rabies vaccines and methods of preparing the same |
| US2965544A (en) * | 1959-02-24 | 1960-12-20 | American Cyanamid Co | Tissue culture propagated canine distemper virus and vaccine thereof |
| US3080291A (en) * | 1960-06-10 | 1963-03-05 | Jensen Salsberg Lab Inc | Serial passage of distemper virus in tissue cultures of chick embryo and canine tissue and vaccine therefrom |
| US3143470A (en) * | 1961-04-24 | 1964-08-04 | Parke Davis & Co | Rabies virus propagation in embryonic cells maintained in a medium containing pancreatic digest of casein |
-
1962
- 1962-08-06 US US214854A patent/US3255080A/en not_active Expired - Lifetime
-
1963
- 1963-07-15 GB GB27896/63A patent/GB1001689A/en not_active Expired
- 1963-08-02 CH CH961363A patent/CH455148A/de unknown
- 1963-08-05 DK DK373863AA patent/DK105426C/da active
- 1963-10-31 FR FR952517A patent/FR3839M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DK105426C (da) | 1966-09-26 |
| US3255080A (en) | 1966-06-07 |
| FR3839M (en:Method) | 1966-01-17 |
| CH455148A (de) | 1968-04-30 |
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