GB0011203D0 - Chemical compounds - Google Patents

Chemical compounds

Info

Publication number
GB0011203D0
GB0011203D0 GBGB0011203.7A GB0011203A GB0011203D0 GB 0011203 D0 GB0011203 D0 GB 0011203D0 GB 0011203 A GB0011203 A GB 0011203A GB 0011203 D0 GB0011203 D0 GB 0011203D0
Authority
GB
United Kingdom
Prior art keywords
chemical compounds
compounds
general formula
invention preferably
activity against
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0011203.7A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rega Foundation
University College Cardiff Consultants Ltd
Cardiff University
Original Assignee
Rega Foundation
University College Cardiff Consultants Ltd
Cardiff University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rega Foundation, University College Cardiff Consultants Ltd, Cardiff University filed Critical Rega Foundation
Priority to GBGB0011203.7A priority Critical patent/GB0011203D0/en
Publication of GB0011203D0 publication Critical patent/GB0011203D0/en
Priority to ES01928079T priority patent/ES2210153T3/es
Priority to DE60101223T priority patent/DE60101223T2/de
Priority to PT01928079T priority patent/PT1280813E/pt
Priority to AT01928079T priority patent/ATE254132T1/de
Priority to JP2001582349A priority patent/JP2003532735A/ja
Priority to AU54945/01A priority patent/AU780879B2/en
Priority to PCT/GB2001/002004 priority patent/WO2001085749A1/en
Priority to DK01928079T priority patent/DK1280813T3/da
Priority to NZ521877A priority patent/NZ521877A/en
Priority to TR2003/02313T priority patent/TR200302313T4/xx
Priority to EP01928079A priority patent/EP1280813B1/en
Priority to US10/275,635 priority patent/US7019135B2/en
Priority to CA002406633A priority patent/CA2406633A1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/14—Pyrrolo-pyrimidine radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GBGB0011203.7A 2000-05-09 2000-05-09 Chemical compounds Ceased GB0011203D0 (en)

Priority Applications (14)

Application Number Priority Date Filing Date Title
GBGB0011203.7A GB0011203D0 (en) 2000-05-09 2000-05-09 Chemical compounds
CA002406633A CA2406633A1 (en) 2000-05-09 2001-05-08 Anti-viral pyrimidine nucleoside analogues
AU54945/01A AU780879B2 (en) 2000-05-09 2001-05-08 Anti-viral pyrimidine nucleoside analogues
DK01928079T DK1280813T3 (da) 2000-05-09 2001-05-08 Antivirale pyrimidin-nukleosidanaloger
PT01928079T PT1280813E (pt) 2000-05-09 2001-05-08 Analogos de nucleosidos de pirimidina antivirais
AT01928079T ATE254132T1 (de) 2000-05-09 2001-05-08 Antivirale pyrimidin nucleoside derivate
JP2001582349A JP2003532735A (ja) 2000-05-09 2001-05-08 抗ウイルスピリミジンヌクレオシド類
ES01928079T ES2210153T3 (es) 2000-05-09 2001-05-08 Analogos de nucleosidos de pirimidina de accion antiviral.
PCT/GB2001/002004 WO2001085749A1 (en) 2000-05-09 2001-05-08 Anti-viral pyrimidine nucleoside analogues
DE60101223T DE60101223T2 (de) 2000-05-09 2001-05-08 Antivirale pyrimidin nucleoside derivate
NZ521877A NZ521877A (en) 2000-05-09 2001-05-08 Pyrimidine nucleoside analogues, their use in treating viral infection and preparation process thereof
TR2003/02313T TR200302313T4 (tr) 2000-05-09 2001-05-08 Antivirütik pirimidin nükleosid analogları
EP01928079A EP1280813B1 (en) 2000-05-09 2001-05-08 Anti-viral pyrimidine nucleoside analogues
US10/275,635 US7019135B2 (en) 2000-05-09 2001-05-08 Anti-viral pyrimidine nucleoside analogues

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0011203.7A GB0011203D0 (en) 2000-05-09 2000-05-09 Chemical compounds

Publications (1)

Publication Number Publication Date
GB0011203D0 true GB0011203D0 (en) 2000-06-28

Family

ID=9891276

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0011203.7A Ceased GB0011203D0 (en) 2000-05-09 2000-05-09 Chemical compounds

Country Status (14)

Country Link
US (1) US7019135B2 (enExample)
EP (1) EP1280813B1 (enExample)
JP (1) JP2003532735A (enExample)
AT (1) ATE254132T1 (enExample)
AU (1) AU780879B2 (enExample)
CA (1) CA2406633A1 (enExample)
DE (1) DE60101223T2 (enExample)
DK (1) DK1280813T3 (enExample)
ES (1) ES2210153T3 (enExample)
GB (1) GB0011203D0 (enExample)
NZ (1) NZ521877A (enExample)
PT (1) PT1280813E (enExample)
TR (1) TR200302313T4 (enExample)
WO (1) WO2001085749A1 (enExample)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7462605B2 (en) 1998-01-23 2008-12-09 Celmed Oncology (Usa), Inc. Phosphoramidate compounds and methods of use
EP1167972B1 (en) 1998-01-23 2017-03-08 Kiadis Pharma Intellectual Property B.V. Enzyme catalyzed therapeutic agents
US6683061B1 (en) 1999-07-22 2004-01-27 Newbiotics, Inc. Enzyme catalyzed therapeutic activation
CA2378187C (en) 1999-07-22 2011-09-13 Newbiotics, Inc. Methods for treating therapy-resistant tumors
GB0009486D0 (en) * 2000-04-17 2000-06-07 Univ Cardiff Chemical compounds
MY164523A (en) 2000-05-23 2017-12-29 Univ Degli Studi Cagliari Methods and compositions for treating hepatitis c virus
ES2624353T3 (es) 2002-11-15 2017-07-13 Idenix Pharmaceuticals Llc 2'-Metil nucleósidos en combinación con interferón y mutación de Flaviviridae
GB0609178D0 (en) 2006-05-09 2006-06-21 Univ Cardiff Novel compounds
US7951789B2 (en) 2006-12-28 2011-05-31 Idenix Pharmaceuticals, Inc. Compounds and pharmaceutical compositions for the treatment of viral infections
CN103842369A (zh) 2011-03-31 2014-06-04 埃迪尼克斯医药公司 用于治疗病毒感染的化合物和药物组合物
GB201111779D0 (en) * 2011-07-08 2011-08-24 Univ Cardiff Chemical compounds
US9403863B2 (en) 2011-09-12 2016-08-02 Idenix Pharmaceuticals Llc Substituted carbonyloxymethylphosphoramidate compounds and pharmaceutical compositions for the treatment of viral infections
TW201331221A (zh) 2011-10-14 2013-08-01 Idenix Pharmaceuticals Inc 嘌呤核苷酸化合物類之經取代的３’，５’－環磷酸酯及用於治療病毒感染之醫藥組成物
US9296778B2 (en) 2012-05-22 2016-03-29 Idenix Pharmaceuticals, Inc. 3′,5′-cyclic phosphate prodrugs for HCV infection
EP2852604B1 (en) 2012-05-22 2017-04-12 Idenix Pharmaceuticals LLC 3',5'-cyclic phosphoramidate prodrugs for hcv infection
HK1203514A1 (en) 2012-05-22 2015-10-30 Idenix Pharmaceuticals Llc D-amino acid compounds for liver disease
PT2861611T (pt) 2012-05-25 2016-10-11 Janssen Sciences Ireland Uc Nucleósidos de espirooxetano de uracilo
WO2014052638A1 (en) 2012-09-27 2014-04-03 Idenix Pharmaceuticals, Inc. Esters and malonates of sate prodrugs
CN104936970A (zh) 2012-10-08 2015-09-23 埃迪尼克斯医药公司 用于hcv感染的2′-氯核苷类似物
WO2014066239A1 (en) 2012-10-22 2014-05-01 Idenix Pharmaceuticals, Inc. 2',4'-bridged nucleosides for hcv infection
WO2014099941A1 (en) 2012-12-19 2014-06-26 Idenix Pharmaceuticals, Inc. 4'-fluoro nucleosides for the treatment of hcv
WO2014137930A1 (en) 2013-03-04 2014-09-12 Idenix Pharmaceuticals, Inc. Thiophosphate nucleosides for the treatment of hcv
EP2970358B1 (en) 2013-03-04 2021-06-30 Idenix Pharmaceuticals LLC 3'-deoxy nucleosides for the treatment of hcv
US20140271547A1 (en) 2013-03-13 2014-09-18 Idenix Pharmaceuticals, Inc. Amino acid phosphoramidate pronucleotides of 2'-cyano, azido and amino nucleosides for the treatment of hcv
WO2014165542A1 (en) 2013-04-01 2014-10-09 Idenix Pharmaceuticals, Inc. 2',4'-fluoro nucleosides for the treatment of hcv
US10005779B2 (en) 2013-06-05 2018-06-26 Idenix Pharmaceuticals Llc 1′,4′-thio nucleosides for the treatment of HCV
WO2015017713A1 (en) 2013-08-01 2015-02-05 Idenix Pharmaceuticals, Inc. D-amino acid phosphoramidate pronucleotides of halogeno pyrimidine compounds for liver disease
WO2015161137A1 (en) 2014-04-16 2015-10-22 Idenix Pharmaceuticals, Inc. 3'-substituted methyl or alkynyl nucleosides for the treatment of hcv

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62255499A (ja) * 1986-04-28 1987-11-07 Teijin Ltd 螢光性ヌクレオシド又はヌクレオチド
GB9708611D0 (en) * 1997-04-28 1997-06-18 Univ Cardiff Chemical compounds
GB9716231D0 (en) * 1997-07-31 1997-10-08 Amersham Int Ltd Base analogues

Also Published As

Publication number Publication date
DK1280813T3 (da) 2004-03-22
AU5494501A (en) 2001-11-20
ES2210153T3 (es) 2004-07-01
US20030176370A1 (en) 2003-09-18
CA2406633A1 (en) 2001-11-15
DE60101223D1 (de) 2003-12-18
JP2003532735A (ja) 2003-11-05
TR200302313T4 (tr) 2004-01-21
EP1280813A1 (en) 2003-02-05
WO2001085749A1 (en) 2001-11-15
AU780879B2 (en) 2005-04-21
NZ521877A (en) 2004-11-26
EP1280813B1 (en) 2003-11-12
PT1280813E (pt) 2004-03-31
DE60101223T2 (de) 2004-09-02
ATE254132T1 (de) 2003-11-15
US7019135B2 (en) 2006-03-28

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)