FR3132214A1 - COSMETIC COMPOSITIONS COMPRISING LARGE QUANTITIES OF HYDROXYPROPYL TETRAHYDROPYRANTRIOL - Google Patents

Abstract

Cosmetic compositions comprising large amounts of hydroxypropyl tetrahydropyrantriol This disclosure relates to cosmetic compositions containing large amounts of hydroxypropyl tetrahydropyrantriol. Cosmetic compositions further include silicone oils, non-emulsifying silicone elastomers, silicone elastomers and water-soluble solvents. Methods of stabilizing cosmetic compositions containing large amounts of hydroxypropyl tetrahydropyrantriol and methods of treating skin with the cosmetic compositions are also disclosed. Figure for the abstract: NONE

Description

COSMETIC COMPOSITIONS COMPRISING LARGE QUANTITIES OF HYDROXYPROPYL TETRAHYDROPYRANTRIOL Area of disclosure

The present disclosure relates to stable cosmetic compositions that include large amounts of hydroxypropyl tetrahydropyrantriol; and methods for stabilizing cosmetic compositions containing large quantities of hydroxypropyl tetrahydropyrantriol. The present disclosure also describes methods of treating skin with the cosmetic compositions.

Summary

In one aspect, the present disclosure relates, among other things, to cosmetic compositions including a surprisingly large amount of hydroxypropyl tetrahydropyrantriol. The cosmetic compositions retain their initial color (white or off-white color) over time, i.e., the cosmetic compositions do not darken or yellow, which is another indicator illustrating the stability of the compositions. Consumers prefer cosmetic compositions that retain their color, since color changes suggest instability, degradation of ingredients and loss of effectiveness. Hydroxypropyl tetrahydropyrantriol provides a multiplicity of cosmetic benefits to the skin, but it is very difficult to incorporate large quantities of hydroxypropyl tetrahydropyrantriol into cosmetic compositions and maintain their stability. The inventors of the present disclosure have developed, among other things, surprisingly stable compositions which include large amounts of hydroxypropyl tetrahydropyrantriol and do not undergo color changes. Thanks to the large amounts of hydroxypropyl tetrahydropyrantriol, the cosmetic compositions provide exceptional cosmetic properties to the skin, for example, reduction of fine lines and wrinkles, improving the production of hyaluronic acid through stimulation of the synthesis of glycosaminoglycans (GAG), a softening of the stratum corneum to relieve cumulative stress on the epidermis and dermis, among others.

In one aspect, the present disclosure relates, among other things, to cosmetic compositions typically in the form of water-in-silicone emulsions. In one embodiment, the cosmetic compositions include:

(a) hydroxypropyl tetrahydropyrantriol;

(b) one or more silicone oils;

(c) one or more non-emulsifying silicone elastomers;

(d) one or more dimethicone copolyol emulsifiers comprising at least one oxyethylene group and at least one oxypropylene group;

(e) water; And

(f) one or more water-soluble solvents.

Non-limiting examples of silicone oils include dimethicone, dimethiconol, cyclopentasiloxane, cyclomethicone, cyclotetrasiloxane, cyclohexasiloxane, cycloheptasiloxane, decamethylcyclopentasiloxane, cyclotetrasiloxane, cyclotrisiloxane, capryldimethicone, caprylyl trimethicone, caprylyl methicone , cetearylmethicone, hexadecylmethicone, hexylmethicone, lauryl methicone, myristyl methicone, phenyl methicone, stearyl methicone, stearyl dimethicone, behenyl dimethicone, trifluoropropyl methicone, cetyl dimethicone, polyphenylmethylsiloxane, dimethylpolysiloxane, methylphenylpolysiloxane, methyltrimethicone, diphenylsiloxyphenyl trimethicone and phenyl trimethicone, and mixtures thereof. In some embodiments, dimethicone is a particularly useful silicone oil.

Non-limiting examples of non-emulsifying silicone elastomers include cross-linked dimethicone polymer, cross-linked vinyl dimethicone polymer, cross-linked dimethicone/vinyl dimethicone polymer, cross-linked dimethicone-3 copolymer, polysilicone-11, and mixtures of these. In some embodiments, cross-linked dimethicone polymers are a particularly useful silicone elastomer.

Non-limiting examples of dimethicone copolyol emulsifiers comprising at least one oxyethylene group and at least one oxypropylene group include bis-PEG/PPG-14/14 dimethicone, bis-isobutyl PEG/PPG-10/7 dimethicone copolymer, bis- PEG/PPG-18/6 dimethicone; bis-PEG/PPG-20/20 dimethicone, bis-PEG/PPG-16/16 dimethicone, cetyl PEG/PPG-15/16 butyl ether dimethicone, cetyl PEG/PPG-15/15 butyl ether dimethicone, cetyl PEG/PPG -7/3 dimethicone, cetyl PEG/PPG-10/1 dimethicone, dimethicone PEG/PPG-7/4 phosphate, dimethicone PEG/PPG-12/4 phosphate, PEG/PPG-28/21 acetate dimethicone, PEG/PPG- 22/22 butyl ether dimethicone, PEG/PPG-23/23 butyl ether dimethicone, PEG/PPG-24/18 butyl ether dimethicone, PEG/PPG-3/10 dimethicone, PEG/PPG-4/12 dimethicone, PEG/PPG -6/11 dimethicone, PEG/PPG-8/14 dimethicone, PEG/PPG-12/16 dimethicone, PEG/PPG-12/18 dimethicone, PEG/PPG-14/4 dimethicone, PEG/PPG-15/5 dimethicone , PEG/PPG-15/15 dimethicone, PEG/PPG-16/2 dimethicone, PEG/PPG-16/8 dimethicone, PEG/PPG-17/18 dimethicone, PEG/PPG-18/12 dimethicone, PEG/PPG- 19/19 dimethicone, PEG/PPG-20/6 dimethicone, PEG/PPG-20/15 dimethicone, PEG/PPG-20/20 dimethicone, PEG/PPG-20/29 dimethicone, PEG/PPG-22/23 dimethicone, PEG/PPG-22/24 dimethicone, PEG/PPG-25/25 dimethicone, PEG/PPG-27/27 dimethicone, PEG/PPG-30/10 dimethicone, PEG/PPG-10/3 oleyl ether dimethicone, and mixtures of these.

Non-limiting examples of water-soluble solvents include glycerin, monoalcohols, polyols (polyhydric alcohols), glycols, and a mixture thereof. In one embodiment, the one or more water-soluble solvents may be selected from propylene glycol, butylene glycol, pentylene glycol, dipropylene glycol, ethanol, isopropanol, t-butyl alcohol and a mixture thereof.

In one embodiment, the cosmetic compositions may optionally include one or more various ingredients. Non-limiting examples of miscellaneous ingredients include various emulsifiers/surfactants other than (d) dimethicone copolyol emulsifiers, preservatives, fragrances, pH regulators, salts, buffers, antioxidants, flavonoids, vitamins, botanical extracts, water filtration agents. UV, proteins, protein hydrolysates and/or isolates, hydrotropes, pearlescent agents, fillers, colorants, mattifying agents, other skin active agents, depigmentation agents, anti-wrinkle agents and mixtures thereof. In one embodiment, the cosmetic composition includes at least one other active agent for the skin, for example, a madecassoside.

The weight ratio of the one or more silicone elastomers (c) to the one or more dimethicone copolyol emulsifiers comprising at least one oxyethylene group and at least one oxypropylene group (d) can vary greatly. However, in one embodiment, the weight ratio may be from about 5:1 to about 1 to 5.

In one embodiment, the cosmetic compositions are part of a kit comprising a cosmetic composition according to the present disclosure and one or more compositions contained separately. In one embodiment, the compositions are received in a device, for example, a device that dispenses the cosmetic composition and the one or more separately contained compositions. In one embodiment, the device distributes the cosmetic composition and the one or more compositions contained separately without mixing them together before distribution. Although large amounts of hydroxypropyl tetrahydropyrantriol are incorporated into the cosmetic compositions, the compositions are unique in that they are compatible with other cosmetic compositions, in particular, other cosmetic compositions for treating the skin.

Another aspect of the present disclosure relates to methods of stabilizing large quantities of hydroxypropyl tetrahydropyrantriol in cosmetic compositions. These methods are described throughout the disclosure and include the incorporation of large amounts of hydroxypropyl tetrahydropyrantriol into the compositions of the present disclosure.

Other features and iterations of the invention are described in greater detail below.

detailed description

A common problem associated with formulating compositions, particularly a composition comprising multiple components, is ensuring physical stability, chemical stability, solubility and the like. Many food, cosmetic, personal care and household product additives in which they are incorporated are difficult to stabilize and solubilize, particularly when used in large quantities. The consequence of stability and solubility problems is significant. For example, stability issues can result in partial or even complete loss of product integrity, loss of color, bad odor, viscosity changes, etc. Stability and solubility issues may result in the application of an increased or reduced amount of the component in question. Regarding active ingredients, stability and solubility issues reduce or eliminate their activity, and prevent the active ingredients from achieving their intended purpose in the desired quantity.

With age, the outer layer of skin (epidermis) becomes thinner, although the number of cell layers remains unchanged. However, the number of pigment-containing cells (melanocytes) decreases. As a result, the skin appears pale and translucent. Large pigmented spots (age spots, brown spots or lentigos) may appear in areas exposed to the sun. Changes in connective tissue reduce the strength and elasticity of the skin. This is known as elastosis. It is more noticeable in areas exposed to the sun (solar elastosis). Elastose produces the weathered, weathered appearance common among farmers, sailors, and others who spend much of their time outdoors. Dehydration increases the risk of skin damage. Poor nutrition can also have a negative influence on the skin, causing dryness, redness and dark circles.

Human skin acts as a primary barrier between the body and its environment. For this barrier function of the skin, the lipid matrix in the outermost layer of the skin (epidermis), the stratum corneum (SC), is crucial. Two of its functions are (1) to prevent excessive water loss through the epidermis and (2) to prevent environmental compounds from penetrating the viable layers of the epidermis and dermis and causing thus an immune reaction. The composition of the SC lipid matrix is dominated by three classes of lipids: cholesterol, free fatty acids and ceramides. These lipids adopt a highly ordered three-dimensional structure of dense stacked lipid layers (lipid lamellae): the lateral and lamellar organization of lipids. How these lipids are ordered depends on the composition of the lipids. A very common skin disease in which the SC lipid barrier is affected is atopic dermatosis (AD).

It is necessary, among other things, to provide compositions that include large amounts of hydroxypropyl tetrahydropyrantriol that reduce the appearance of fine lines and wrinkles, improve the production of hyaluronic acid through stimulation of the synthesis of glycosaminoglycans ( GAG), soften the stratum corneum to release cumulative stress on the epidermis and dermis, among other benefits. The cosmetic compositions of the present dossier meet these needs and further reduce/limit the effects of aging, prevent/reduce sensitivity and inflammation of the skin, and improve the luminosity, smoothness and overall appearance of the skin, and the like.

In one aspect, the present disclosure relates to, among other things, a stable cosmetic composition that includes large quantities of hydroxypropyl tetrahydropyrantriol and methods of stabilizing large quantities of hydroxypropyl tetrahydropyrantriol in cosmetic compositions. In one embodiment, the compositions include:

(a) about 10 to about 50% by weight of hydropropyl tetrahydropyrantriol;

(b) about 5 to about 50% by weight of one or more silicone oils;

(c) about 0.1 to about 10% by weight of one or more non-emulsifying silicone elastomers;

(d) about 0.1 to about 10% by weight of one or more dimethicone copolyol emulsifiers comprising at least one oxyethylene group and at least one oxypropylene group;

(e) water; And

(f) from about 0.1 to about 40% by weight of one or more water-soluble solvents;

in which the composition is in the form of a water-in-silicone emulsion and all weight percentages are based on the total weight of the composition.

(has) Hydroxypropyl t etra hydropyrantriol

Hydroxypropyl tetrapyrantriol is a sugar-protein hybrid made from xylose and can effectively activate the synthesis of GAGs (glycosamineoglycans), promote hyaluronic acid production, collagen synthesis, adhesion between dermis and epidermis , synthesis of epidermal structural components, regeneration of damaged tissue and maintenance of skin elasticity.

The quantity of hydroxypropyl tetrapyrantriol in cosmetic compositions will vary. However, in one embodiment, the amount of hydroxypropyl tetrapyrantriol is from about 10 weight percent to about 50 weight percent based on the total weight of the composition. In other embodiments, the amount of hydroxypropyl tetrapyrantriol in the composition is about 12 to about 50 weight percent, about 12 to about 45 weight percent, about 12 to about 40 weight percent , from about 12 to about 35% by weight, from about 12 to about 30% by weight, from about 15 to about 50% by weight, from about 15 to about 45% by weight, from about 15 to about approximately 40% by weight, approximately 15 to approximately 35% by weight, approximately 15 to approximately 30% by weight, approximately 20 to approximately 50% by weight, approximately 20 to approximately 45% by weight, from about 20 to about 40% by weight, from about 20 to about 35% by weight, from about 20 to about 30% by weight, from about 25 to about 50% by weight, from about 25 to about 45% by weight, from about 25 to about 40% by weight, from about 25 to about 35% by weight, from about 30 to about 50% by weight, from about 30 to about 45% by weight, d 'about 30 to about 40% by weight, based on the total weight of the cosmetic composition.

(b) Oil s silicone

Non-limiting examples of silicones include dimethicone, dimethiconol, cyclomethicone, polysilicone-11, phenyl trimethicone, trimethylsilylamodimethicone and stearoxytrimethylsilane. In a preferred embodiment, the one or more silicone oils are non-volatile silicone oils. Useful silicone oils include polydimethylsiloxanes (PDMSs), polydimethylsiloxanes comprising alkyl and alkoxy groups that are pendant and/or at the end of the silicone chain, which groups each contain from 2 to 24 carbon atoms, or phenyl silicones, such as phenyl trimethicones, phenyl dimethicones, phenyl(trimethylsiloxy)diphenylsiloxanes, diphenyl dimethicones, diphenyl(methyldiphenyl)trisiloxanes or (2-phenylethyl)trimethylsiloxysilicates. Other examples of silicone oils that may be mentioned include linear or cyclic volatile silicones, such as those having a viscosity of 8 centistokes (8 x 106 m2/s) and/or containing 2 to 7 silicone atoms. These silicones optionally include alkyl or alkoxy groups containing 1 to 10 carbon atoms. Non-limiting examples of volatile silicone oils include octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, dodecamethylcyclohexasiloxane, heptamethylhexyltrisiloxane, heptamethyloctyltrisiloxane, hexamethyldisiloxane, octamethyltrisiloxane, decamethyltetrasiloxane and dodecamethylpentasiloxane, or mixtures thereof.

In a preferred embodiment, the cosmetic compositions include one or more silicone oils selected from dimethicone, dimethiconol, cyclomethicone, polysilicone-11, phenyl trimethicone and amodimethicone, preferably dimethicone.

In another embodiment, the cosmetic compositions include one or more amino functionalized silicones. Non-limiting examples include amodimethicone , bis-hydroxy/methoxy amodimethicones, bis-cetearyl amodimethicone, amodimethicone, bis(C13-15 alkoxy) PG amodimethicones, aminopropyl phenyl trimethicones, aminopropyl dimethicones, bis-amino PEG/PPG-41/3 aminoethyl PG -propyl dimethicones, caprylyl methicones, and a mixture thereof. Amodimethicone is a particularly useful amino functionalized silicone.

In a preferred embodiment, the one or more silicone oils are chosen from dimethicone, dimethiconol, cyclopentasiloxane, cyclomethicone, cyclotetrasiloxane, cyclohexasiloxane, cycloheptasiloxane, decamethylcyclopentasiloxane, cyclotetrasiloxane, cyclotrisiloxane, capryldimethicone, caprylyl trimethicone, caprylyl methicone, cetearylmethicone , hexadecylmethicone, hexylmethicone , lauryl methicone, myristyl methicone, phenyl methicone, stearyl methicone, stearyl dimethicone, behenyl dimethicone, trifluoropropyl methicone, cetyl dimethicone, polyphenylmethylsiloxane, dimethylpolysiloxane, methylphenylpolysiloxane, methyltrimethicone, diphenylsiloxyphenyl trimethicone and phenyl trimethicone, and mixtures of these.

Preferably, the one or more silicone oils include dimethicone, and optionally one or more other silicone oils.

The total amount of the one or more silicone oils in the cosmetic compositions will vary but in various embodiments is from about 5 to about 50% by weight, based on the total weight of the cosmetic composition. In other embodiments, the total amount of the one or more silicone oils is about 5 to about 45% by weight, about 5 to about 40% by weight, about 5 to about 35% by weight, weight, from about 10 to about 45% by weight, from about 10 to about 40% by weight, from about 10 to about 35% by weight, from about 15 to about 50% by weight, from about 15 about 45% by weight, about 15 to about 40% by weight, about 15 to about 35% by weight, about 20 to about 50% by weight, about 20 to about 45% by weight , from about 20 to about 40% by weight, from about 20 to about 35% by weight, from about 25 to about 50% by weight, from about 25 to about 45% by weight, from about 25 to about about 40% by weight or about 25 to about 35% by weight, based on the total weight of the cosmetic composition.

(vs) Non-emulsifying silicone elastomers

The term "non-emulsifying" as used in relation to "silicone elastomers" defines crosslinked organopolysiloxane elastomers not containing hydrophilic chains, and in particular, not containing polyoxyalkylene units (in particular, polyoxyethylene or polyoxypropylene) nor polyglyceryl units.

Non-limiting examples of non-emulsifying silicone elastomers include cross-linked polymers of dimethicone, cross-linked polymers of (dimethicone/phenyl divinyl methicone), cross-linked polymers of (dimethicone/vinyl dimethicone/methicone), cross-linked polymers of (dimethicone/ vinyl dimethicone) and crosslinked polymers of (diphenyl dimethicone/vinyl diphenyl dimethicone/silsesquioxane). Preferred non-emulsifying silicone elastomers include cross-linked dimethicone polymer, cross-linked vinyl dimethicone polymer, cross-linked dimethicone/vinyl dimethicone polymer, cross-linked dimethicone-3 copolymer, polysilicone-11, and mixtures thereof.

Non-emulsifying silicone elastomers can be obtained from curable organopolysiloxanes. Examples thereof are: addition reaction curing organopolysiloxane compositions which cure under platinum metal catalysis through the addition reaction between a diorganopolysiloxane containing SiH and an organopolysiloxane having vinyl groups bonded to silicone; condensation-curing organopolysiloxane compositions that cure in the presence of an organotin compound through a dehydrogenation reaction between the hydroxyl-terminated diorganopolysiloxane and the SiH-containing diorganopolysiloxane; condensation curing organopolysiloxane compositions which cure in the presence of an organotin compound or a titanate ester, through a condensation reaction between a hydroxyl-terminated diorganopolysiloxane and a hydrolyzable organosilane (this condensation reaction is illustrated by the reactions of dehydration, alcohol release, oxime release, amine release, amide release, carboxyl release and ketone release); peroxide-curable organopolysiloxane compositions that thermally cure in the presence of an organoperoxide catalyst; and organopolysiloxane compositions that are cured by high energy radiation, such as gamma rays, ultraviolet radiation or electron beams. The silicone elastomer is preferably obtained by addition reaction curing of organopolysiloxane compositions which cure under platinum metal catalysis through the addition reaction between a diorganopolysiloxane containing SiH and an organopolysiloxane having vinyl groups linked to silicone.

The total amount of the one or more non-emulsifying silicone elastomers may be from about 0.1 to about 10% by weight, based on the total weight of the cosmetic composition. In some embodiments, the total amount of the one or more non-emulsifying silicone elastomers may be in an amount of about 0.1 to about 8 wt.%, about 0.1 to about 5 wt.%, d 'about 0.5 to about 10% by weight, about 0.5 to about 8% by weight, about 0.5 to about 5% by weight, about 1 to about 10% by weight, d 'about 1 to about 8% by weight, about 1 to about 5% by weight or about 1 to about 3% by weight, from 1.5 to about 10% by weight, about 1.5 to about about 8% by weight, about 1.5 to about 5% by weight or about 1.5 to about 3% by weight, based on the total weight of the cosmetic composition.

(d) D emulsifiers i meth icon vs polyol

The expression "dimethicone copolyol emulsifier comprising at least one oxyethylene group and at least one oxypropylene group" as used throughout the present disclosure is an oxypropylenated and oxyethylenated polydimethylsiloxane which may optionally contain at least one alkyl group. Thus, the expression "dimethicone copolyol emulsifier comprising at least one oxyethylene group and at least one oxypropylene group" encompasses alkyl dimethicone copolyol emulsifiers (alkyl dimethicone copolyol emulsifiers comprising at least one oxyethylene group and at least one oxypropylene group ). For example, cetyl dimethicone copolyol emulsifiers (e.g., cetyl PEG/PPG-10/1 dimethicone) are considered dimethicone copolyol emulsifiers comprising at least one oxyethylene group and at least one oxypropylene group. The at least one possible alkyl group may contain 8 or more carbon atoms, in particular, C ₈ -C ₂₂ .

In various embodiments, it is preferable that at least one of the one or more dimethicone copolyol emulsifiers is a C ₈ -C ₂₂ alkyl dimethicone copolyol emulsifier. Non-limiting examples include compounds represented by formula (I) below.

in which :

PE represents (—C ₂ H ₄ O) _x —(C ₃ H ₆ O) _y —R, R being chosen from a hydrogen atom and an alkyl radical containing from 1 to 4 carbon atoms, x ranging from 1 to 100 and going from 1 to 80;

m ranging from 1 to 40;

n ranging from 10 to 200;

o ranging from 1 to 100;

p ranging from 7 to 21; And

q ranging from 0 to 4.

In particular, R = H; m = 1 to 10; n = 10 to 100; o = 1 to 30; p = 15 and q = 3.

Non-limiting, but particularly preferable examples of C ₈ -C ₂₂ alkyl dimethicone copolyols include PEG/PPG-18/18 dimethicone, cetyl PEG/ PPG -10/1 dimethylone and mixtures thereof .

In various embodiments, the one or more dimethicone copolyol emulsifiers may be selected from bis-PEG/PPG-14/14 dimethicone, bis-isobutyl PEG/PPG-10/7 dimethicone copolymer, bis-PEG/PPG-18 /6 dimethicone; bis-PEG/PPG-20/20 dimethicone, bis-PEG/PPG-16/16 dimethicone, cetyl PEG/PPG-15/16 butyl ether dimethicone, cetyl PEG/PPG-15/15 butyl ether dimethicone, cetyl PEG/PPG -7/3 dimethicone, cetyl PEG/PPG-10/1 dimethicone, dimethicone PEG/PPG-7/4 phosphate, dimethicone PEG/PPG-12/4 phosphate, PEG/PPG-28/21 acetate dimethicone, PEG/PPG- 22/22 butyl ether dimethicone, PEG/PPG-23/23 butyl ether dimethicone, PEG/PPG-24/18 butyl ether dimethicone, PEG/PPG-3/10 dimethicone, PEG/PPG-4/12 dimethicone, PEG/PPG -6/11 dimethicone, PEG/PPG-8/14 dimethicone, PEG/PPG-12/16 dimethicone, PEG/PPG-12/18 dimethicone, PEG/PPG-14/4 dimethicone, PEG/PPG-15/5 dimethicone , PEG/PPG-15/15 dimethicone, PEG/PPG-16/2 dimethicone, PEG/PPG-16/8 dimethicone, PEG/PPG-17/18 dimethicone, PEG/PPG-18/12 dimethicone, PEG/PPG- 19/19 dimethicone, PEG/PPG-20/6 dimethicone, PEG/PPG-20/15 dimethicone, PEG/PPG-20/20 dimethicone, PEG/PPG-20/29 dimethicone, PEG/PPG-22/23 dimethicone, PEG/PPG-22/24 dimethicone, PEG/PPG-25/25 dimethicone, PEG/PPG-27/27 dimethicone, PEG/PPG-30/10 dimethicone, PEG/PPG-10/3 oleyl ether dimethicone, and mixtures of these.

The total amount of the one or more dimethicone copolyol emulsifiers will vary but in various embodiments is from about 0.1 to about 10% by weight, based on the total weight of the cosmetic composition. In other embodiments, the total amount of the one or more dimethicone copolyol emulsifiers is about 0.1 to about 8 wt.%, about 0.1 to about 5 wt.%, about 0 .5 to about 10% by weight, about 0.5 to about 8% by weight, about 0.5 to about 5% by weight, about 1 to about 10% by weight, about 1 to about 8% by weight, from about 1 to about 5% by weight, or from about 1 to about 3% by weight, from 1.5 to about 10% by weight, from about 1.5 to about 8 % by weight, from about 1.5 to about 5% by weight or from about 1.5 to about 3% by weight, based on the total weight of the cosmetic composition.

Ratio of (c) to (d)

The weight ratio of the one or more non-emulsifying silicone elastomers (c) to the one or more dimethicone copolyol emulsifiers (d) may vary. In one embodiment, the ratio of the one or more non-emulsifying silicone elastomers (c) to the one or more dimethicone copolyol emulsifiers (d) is from about 1:10 to about 10:1, from about 1: 8 to 8:1, approximately 1:6 to approximately 6:1, approximately 1:5 to approximately 5:1, approximately 1:4 to 4:1, approximately 1:3 to approximately 3 to about 1. In other embodiments, the ratio of the one or more non-emulsifying silicone elastomers (c) to the one or more dimethicone copolyol emulsifiers (d) is from about 1:5 to about 5:1. , from approximately 1:4 to approximately 4:1, from approximately 1:3 to approximately 3:1 or from approximately 1:2 to approximately 2:1.

(e) Water

The quantity of water in cosmetic compositions can vary and will vary depending on the quantity of other components in the cosmetic compositions. In one embodiment, the total amount of water in the compositions is from about 0.1 to about 70% by weight, based on the total weight of the cosmetic composition. In another embodiment, the total amount of water is 0.1 to about 60 wt.%, about 0.1 to about 50 wt.%, about 0.1 to about 40 wt.% , from about 0.1 to about 30% by weight, from about 0.1 to about 20% by weight, from about 0.1 to about 10% by weight or from about 0.1 to about 5% by weight, based on the total weight of the cosmetic composition. In other preferred embodiments, the amount of water in the cosmetic composition is from 5 to approximately 50% by weight, from approximately 10 to approximately 45% by weight, from approximately 10 to approximately 40% by weight, from about 10 to about 35% by weight, from about 15 to about 50% by weight, from about 15 to about 45% by weight, from about 15 to about 40% by weight, from about 15 to about 35% by weight, from about 20 to about 50% by weight, from about 20 to about 45% by weight, from about 20 to about 40% by weight, from about 20 to about 35% by weight, d 'about 25 to about 50% by weight, about 25 to about 45% by weight, about 25 to about 40% by weight or about 25 to about 35% by weight, based on the total weight of the cosmetic composition.

(f) Water-soluble solvents

The term "water-soluble solvent" is interchangeable with the term "water-miscible solvent" and means a compound which is liquid at 25°C and atmospheric pressure (760 mmHg), and which has a solubility of at least 50% in water under these conditions. In one embodiment, the water-soluble solvents have a solubility of at least 60%, 70%, 80% or 90%. Non-limiting examples of one or more water-soluble agents are chosen from glycerin, monoalcohols, polyols (polyhydric alcohols), glycols and a mixture thereof.

As non-limiting examples of organic solvents, mention may be made of monoalcohols and polyols such as ethyl alcohol, propyl alcohol, isopropyl alcohol, benzyl alcohol, 4-tert-butylcyclohexanol and alcohol phenylethyl, or glycols or glycolic ethers such as, for example, monomethyl, monoethyl and monobutyl ethers of ethylene glycol, propylene glycol or ethers thereof, for example, monomethyl ether of propylene glycol, butylene glycol, hexylene glycol , dipropylene glycol as well as alkyl ethers of diethylene glycol, for example, monoethyl ether or monobutyl ether of diethylene glycol. Other suitable examples of organic solvents are ethylene glycol, propylene glycol, butylene glycol, hexylene glycol, propane diol and glycerin. Organic solvents can be volatile or non-volatile compounds.

Other non-limiting examples of water-soluble solvents include alkanediols (polyhydric alcohols) such as glycerin, 1,2,6-hexanetriol, trimethylolpropane, ethylene glycol, propylene glycol, diethylene glycol, triethylene glycol, tetraethylene glycol, pentaethylene glycol, dipropylene glycol , 2-butene-1,4-diol, 2-ethyl-1,3-hexanediol, 2-methyl-2,4-pentanediol, (caprylyl glycol), 1,2-hexanediol, 1,2-pentanediol and 4- methyl-1,2-pentanediol; alkyl alcohols having 1 to 4 carbon atoms such as ethanol, methanol, butanol, propanol and isopropanol; glycolic ethers such as ethylene glycol monomethyl ether, ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, ethylene glycol monomethyl ether acetate, diethylene monomethyl ether glycol, diethylene glycol monoethyl ether, diethylene glycol mono-n-propyl ether, ethylene glycol mono-iso-propyl ether, diethylene glycol mono-iso-propyl ether, ether ethylene glycol mono-n-butyl ether, ethylene glycol mono-t-butyl ether, diethylene glycol mono-t-butyl ether, 1-methyl-1-methoxybutanol, propylene monomethyl ether glycol, propylene glycol monoethyl ether, propylene glycol mono-t-butyl ether, propylene glycol mono-n-propyl ether, propylene glycol mono-iso-propyl ether, propylene glycol mono-ethyl ether, monomethyl ether of dipropylene glycol, dipropylene glycol monoethyl ether, dipropylene glycol mono-n-propyl ether and dipropylene glycol mono-iso-propyl ether; 2-pyrrolidone, N-methyl-2-pyrrolidone, 1,3-dimethyl-2-imidazolidinone, formamide, acetamide, dimethyl sulfoxide, sorbitol, sorbitan, acetin, triacetin, sulfolane, and a mixture thereof.

Polyhydric alcohols are also useful. Examples of polyhydric alcohols include glycerin, ethylene glycol, diethylene glycol, triethylene glycol, propylene glycol, dipropylene glycol, tripropylene glycol, 1,3-butanediol, 2,3-butanediol, 1,4-butanediol, 3-methyl-1 ,3-butanediol, 1,5-pentanediol, tetraethylene glycol, 1,6-hexanediol, 2-methyl-2,4-pentanediol, polyethylene glycol, 1,2,4-butanetriol, 1,2,6-hexanetriol, and a mixture of these. Polyol compounds can also be used. Non-limiting examples include aliphatic diols, such as 2-ethyl-2-methyl-1,3-propanediol, 3,3-dimethyl-1,2-butanediol, 2,2-diethyl-1,3-propanediol, 2 -methyl-2-propyl-1,3-propanediol, 2,4-dimethyl-2,4-pentanediol, 2,5-dimethyl-2,5-hexanediol, 5-hexene-1,2-diol and 2-ethyl -1,3-hexanediol, and a mixture thereof.

In one embodiment, the cosmetic compositions of the present disclosure include one or more glycols and/or one or more alcohols, for example, one or more water-soluble solvents chosen from propylene glycol, butylene glycol, pentylene glycol, dipropylene glycol, ethanol, isopropanol, tert-butyl alcohol, and mixtures thereof.

The total amount of the one or more water-soluble solvents may be from about 0.1 to about 50% by weight, based on the total weight of the cosmetic composition. In various embodiments, the total amount of the one or more water-soluble solvents may be from about 0.1 to about 40 weight percent, from about 0.1 to about 30 weight percent, from about 0.1 to about about 20% by weight, from 0.1 to about 15% by weight, from about 0.1 to about 10% by weight, from about 0.1 to about 5% by weight, from about 1 to about 20 % by weight, from about 1 to about 15% by weight, from about 1 to about 10% by weight or from about 1 to about 5% by weight, based on the total weight of the cosmetic composition.

(g) Miscellaneous ingredients

The cosmetic compositions of the present disclosure may optionally include one or more various ingredients. Miscellaneous ingredients are ingredients that are compatible with the cosmetic compositions and do not disrupt or materially affect the basic and novel properties of the cosmetic compositions. The various ingredients commonly used in cosmetics are known in the art. Non-limiting examples of miscellaneous ingredients include various emulsifiers/surfactants other than (d) dimethicone copolyol emulsifiers, preservatives, fragrances, acidity regulators, salts, buffers, antioxidants, flavonoids, vitamins, botanical extracts, conditioning agents. UV filtration, proteins, hydrolysates and/or protein isolates, hydrotropes, pearlescent agents, fillers, dyes, mattifying agents, other active agents for the skin, depigmentation agents, anti-wrinkle agents, etc. In a preferred embodiment, the cosmetic compositions of the present disclosure include one or more active agents for the skin, in particular, a madecassoside. Non-limiting examples of other various ingredients which may optionally be included (or excluded) from cosmetic compositions are provided below.

Various emulsifiers/surfactants

Various emulsifiers/surfactants may optionally be included in the cosmetic compositions. Miscellaneous emulsifiers/surfactants are those other than the dimethicone copolyol emulsifiers of (d). The various emulsifiers/surfactants may be anionic, cationic and/or amphoteric/zwitterionic.

Antioxidants

Examples of antioxidants include tocopherols (e.g., d-α-tocopherol, d-β-tocopherol, d-γ-tocopherol, d-delta-tocopherol), tocotrienols (e.g., d-α-tocotrienol, d- β-tocotrienol, d-γ.-tocotrienol, d-delta-tocotrienol,) and vitamin E (α-tocopherol acetate). These compounds may be isolated from natural sources, prepared by synthetic means, or mixtures thereof. Vitamin E preparations enriched with tocotrienol can be obtained by fractionating vitamin E preparations to remove part of the tocopherols and recover a preparation more highly concentrated in tocotrienol. Useful tocotrienols are natural products isolated from, for example, wheat germ oil, grain oil or palm oil using high performance liquid chromatography, or isolated by alcohol extraction and/or molecular distillation of barley, brewing grain or oats. As used herein, the term “tocotrienols” includes the tocotrienol-rich fractions obtained from these natural products as well as the pure compounds. Increased glutathione peroxidase activity protects the skin against oxidative stress.

Vitamin C and its derivatives can be used, including ascorbic acid, sodium ascorbate, and the fatty soluble esters tetrahexyldecyl ascorbate and ascorbyl palmitate, magnesium ascorbyl phosphate, ascorbyl-glucoside, glucosamine ascorbate, ascorbyl acetate, etc. . Furthermore, plant extracts containing a large amount of vitamin C such as camu berry (Myrciaria dubia), acerola, emblica officinalis and cinorrhodon and citrus bioflavonoids can be used, and water-soluble bioflavonoids such as hesperidin methyl chalcone can also be used. used.

Sesame (Sesamum indicum) or sesame lignan can also be added. Sesame and its lignans (fibrous compounds associated with sesame) act as antioxidants. Sesame seed lignans significantly improve vitamin E activity.

Furthermore, carotenoids, particularly the xanthophyll type, are also useful antioxidants that can be used. Xanthopyl carotenoids include molecules, such as lutein, canthaxanthin, cryptoxanthin, zeaxanthin, and astaxanthin. Xanthophylls protect compounds, such as vitamin A, vitamin E and other carotenoids.

Flavonoids can also serve as antioxidants. In some cases, the flavonoid is a flavanone (derived from 2,3-dihydro-2-phenylchromen-4-one). Flavones include: Butin, Eriodictyol, Hesperetin, Hesperidin, Homoeriodictyol, Isosakuranetin, Naringenin, Naringin, Pinocembrin, Poncirin, Sakuranetin, Sakuranine and Sterubin. The flavonoid may be a flavanonol (3-hydroxy-2,3-dihydro-2-phenylchromen-4-one derivative). Flavanols include: Taxifoline, Aromadedrine, Chrysandroside A, Chrysandroside B, Xeractinol, Astilbin and Fustin. The flavonoid may be a flavone (2-phenylchromen-4-one derivative). Flavones include: Apigenin, Luteolin, Tangeritin, Chrysin, Baicalein, Scutellarein, Wogonin, Synthetic Flavones: Diosmin and Flavoxate. The flavonoid may be a flavonol (3-hydroxy-2-phenylchromen-4-one derivative). Flavonols include: 3-Hydroxyflavone, Azaleatin, Fisetin, Galangin, Gossypetin, Kaempferide, Kaempferol, Isorhamnetin, Morin, Myricetin, Natsudaidaine, Pachypodol, Quercetin, Rhamnazine, Rhamnetin, Azalein, Hyperoside, Isoquercitin, Kaempferitrin, Myricitrin, Quercitrine, Robinin, Rutin, Spiraeoside, Xanthorhamnine, Amurensine, Icariine, and Troxerutin. The flavonoid may be a flavan-3-ol (derived from 2-phenyl-3,4-dihydro-2H-chromen-3-ol). Flavan-3-ols include: Catechin, Epicatechin, Epigallocatechin, Epicatechin gallate, Epigallocatechin gallate, Epiafzelechin, Fisetinidol, Guibourtinidol, Mesquitol and Robinetinidol. The flavonoid may be a flavan-4-ol (derived from 2-phenylchroman-4-ol). Flavan-4-ols include: Apiforol and Luteoforol. The flavonoid may be an isoflavone (3-phenylchromen-4-one derivative). Isoflavones include: Genistein, Daidzein, Biochanin A, Formononetin and Equol metabolite of Daidzein.

The antioxidant may be an anthocyanidin (2-phenylchromenylium cation derivative). Anthocyanidins include: Aurantinidin, Cyanidin, Delphinidin, Europinidin, Luteolinidin, Pelargonidin, Malvidin, Peonidin, Petunidin, Rosinidin and Xanthone.

The antioxidant may be a dihydrochalcone (derived from 1,3-diphenyl-1-propanone). Dihydrochalcones include: Phloretin, Dihydrochalcone phloretin Phlorizin, Aspalathin, Naringin dihydrochalcone, Neohesperidin dihydrochalcone and Nothofagin. Without limiting the mode of action of the invention, dihydrochalcones can exert an antioxidant effect by reducing reactive free radicals, such as reactive oxygen and reactive nitrogen species.

The antioxidant may be an anthocyanin. Anthocyanins and their derivatives are antioxidants. Anthocyanins encompass a class of flavonoid compounds that are naturally occurring water-soluble compounds, responsible for the red, purple, and blue colors of many fruits, vegetables, cereal grains, and flowers. Furthermore, anthocyanins are collagenase inhibitors. Collagenase inhibition helps prevent and reduce wrinkles, increased skin elasticity, etc., which are caused by a reduction in skin collagen. Anthocyanins can be obtained from any part of various plant sources, such as fruit, flower, stem, leaves, root, bark or seeds. One skilled in the art will understand that certain parts of the plant may contain higher natural levels of anthocyanins, and therefore, these parts are used to obtain the desired anthocyanins. In some cases, antioxidants may include one or more betacyanins. Betacyanins, such as anthocyanins, can be obtained from natural sources and are antioxidants.

The antioxidant may be a phenylpropanoid (cinnamic acid derivative). Phenylpropanoids include: cinnamic acid, caffeic acid, ferulic acid, transferulic acid (including its pharmacore antioxidant 2,6-dihydroxyacetophenome), 5-hydroxyferulic acid, sinapic acid, coumaryl alcohol, coniferyl alcohol, sinapyl alcohol, eugenol, chavicol, safrole , P-coumaric acid and sinapinic acid. Without limiting the mode of action of the invention, phenylpropanoids can neutralize free radicals.

The antioxidant may be a chalcone (1,3-diphenyl-2-propen-1-one derivative). Chalcones include: butein, okanin, carthamine, marein, sophoradine, xanthohumol, flavokvain A, flavokavin B, flavokavin C and synthetic safalcone.

The antioxidant may be a curcuminoid. Curcuminoids include: curcumin, desmethoxycurcumin, bis-Desmethoxycurcumin, tetrahydrocurcumin and tetrahydrocurcuminoids. Curcumin and tetrahydrocurcuminoids can be derived from rhizomes of Curcuma longa. Tetrahydrocurcumin, a metabolite of curcumin, has been shown to be a more powerful and stable antioxidant than curcumin.

The antioxidant may be a tannin. Tannins include: tannin, terflavin B, glucogallin, Dgallic acid and quercitannic acid.

The antioxidant may be a stilbenoid. Stilbenoids include: resveratrol, pterostilbene and piceatannol. Resveratrol may include, but is not limited to, 3,5,4'-trihydroxystilbene, 3,4,3',5'-tetrahydroxystilbene (piceatannol), 2,3',4,5'-tetrahydroxystilbene (oxyresveratrol) , 4,4'-dihydroxystilbene and alpha and beta glucoside, galactoside and mannoside derivatives thereof.

The antioxidant may be a coumarin (2H-chromen-2-one derivatives). Coumarins include: 4-hydroxycoumarin, umbelliferone, aesculetin, herniarin, auraptene and dicoumarol.

The antioxidant may be a carotenoid. Carotenoids include: beta-Carotene, alpha-Carotene, gamma-Carotene, beta-Cryptoxanthin, Lycopene, Lutein and Idebenone. Sesame (Sesamum indicum) or sesame lignan can also be added. Sesame or its lignans (fibrous compounds associated with sesame) act as antioxidants. Sesame seed lignans significantly improve vitamin E activity.

The antioxidant can be: a xanthone, a butylated hydroxytoluene, a 2,6-Di-tert-butylphenol, a 2,4-dimethyl-6-tert-butylphenol, a gallic acid, a eugenol, a uric acid, an acid alpha-lipoic acid, ellagic acid, chicoric acid, chlorogenic acid, rosmarinic acid, salicyclic acid, acetylcysteine, S-Allyl cysteine, barbigerone, chebulagic acid, edaravone, ethoxyquin, glutathione, a hydroxytyrosol, an idebenone, a melatonin, an N-acetylserotonin, a nordihydroguaiaretic acid, an oleocanthal, an oleuropein, a paradol, a piceatannol, a probucol, a propyl gallate, a protocatechuic acid, a pyritinol, a rutin, a diglucoside of secoisolariciresinol, sesamin, sesamol, silibinin, silymarin, theaflavin, theaflavin digallate, thmoquinone, trolox, tyrosol, polyunsaturated fatty acids and sulfur-based antioxidants, such as methionine or lipoic acid.

Active agents for the skin

Non-limiting examples of active agents for the skin include madecassoside, retinoic acid, benzoyl peroxide, sulfur, (pyridoxine or) vitamin B6 chloride, selenium, blends of fennel and cinnamon extracts, tea and octanoylglycine such as -- Sépicontrol A5 TEA from Seppic -- mixture of cinnamon, sarcosine and octanoylglycine marketed in particular by Seppic under the brand name Sepicontrol A5; -- zinc salts such as zinc gluconate, zinc pyrrolidonecarboxylate (or zinc pidolate), zinc lactate, zinc aspartate, zinc carboxylate, zinc salicylate, zinc cysteate; -- derivatives in particular copper and copper pidolate in the form of Cuivridone Solabia -- plant extracts of Arnica montana, Cinchona succirubra, Eugenia caryophyllata, Humulus lupulus, Hypericum perforatum, Mentha pipenta Rosmarinus officinalis, Salvia officinalis and Thymus vulgaris, all marketed for example by Maruzen; -- extracts of meadowsweet (Spiraea ulmaria), such as those marketed under the brand name Sébonormine by Silab; -- extracts of alga Laminaria saccharina, such as those marketed under the name Phlorogine by Biotechmarine; -- root extracts from mixtures of burnet (Sanguisorba officinalis/Poterium officinale), ginger rhizomes (Zingiber officinalis) and cinnamon bark (Cinnamomum cassia), such as those marketed under the name Sebustop by Solabia; -- flaxseed extracts such as those marketed under the name Linumine by Lucas Meyer -- phellodendron extracts such as those marketed under the name Phellodendron extract BG by Maruzen or Oubaku liquid B by Ichimaru Pharcos; -- extracts from mixtures of argan oil from Serenoa serrulata (saw palmetto) and sesame seeds such as those marketed under the name Regu SEB by Pentapharm; -- mixtures of extracts of willowherb, Terminalia chebula, nasturtium and bioavailable zinc (microalgae), such as those marketed under the name Seborilys Green Tech; -- extracts of Pygeum afrianum such as those marketed under the name Pygeum afrianum sterolic lipid extract by Euromed; -- extracts of Serenoa serrulata such as those marketed under the name Viapure Sabal by Actives International, and those marketed by the company Euromed; -- extracts of mixtures of plantain, Berberis aquifolium and sodium salicylate such as those marketed under the name Seboclear Rahn; -- clove extract such as those marketed under the name Clove extract powder by Maruzen; -- argan oil such as that marketed under the name Lipofructyl Laboratories Serobiologique; -- lactic protein filtrates, such as those marketed under the name Normaseb by Sederma; -- extracts of laminaria algae, such as those marketed under the name Laminarghane by Biotechmarine; -- oligosaccharides from Laminaria digitata algae, such as those marketed under the name Phycosaccharide 30 AC by the company Codif; -- sugar cane extracts such as those marketed under the name Policosanol by the company Sabinsa; -- sulfonated shale oil, such as that marketed under the name Ichthyol Pale by Ichthyol; -- extracts of meadowsweet (Spiraea ulmaria) such as those marketed under the name Cytobiol Ulmaire by the company Libiol; -- sebacic acid, marketed in particular in the form of sodium polyacrylate gel under the name Sebosoft by Sederma; -- glucomannans extracted from a konjac tuber and modified with alkylsulfonate chains such as those marketed under the name Biopol Beta by Arch Chemical; -- extracts of Sophora angustifolia, such as those marketed under the name Sophora powder or Sophora extract by Bioland; -- extracts of cinchona succirubra bark such as those marketed under the name Red Bark HS by Alban Muller; -- extracts of Quillaja saponaria such as those marketed under the name Panama wood HS by Alban Muller; -- glycine grafted onto an undecylenic chain, such as that marketed under the name Lipacide UG OR by SEPPIC; -- mixture of oleanolic acid and nordihydroguaiaretic acid, such as that marketed in the form of a gel under the name AC.Net by Sederma; -- phthalimidoperoxyhexanoic acid; -- citrate tri (C12-C13) marketed under the name COSMACOL.RTM ECI by Sasol; trialkyl citrate (C14-C15) marketed under the name COSMACOL.RTM. ECL by Sasol; -- hydroxydecanoic acid, including mixtures of hydroxydecanoic acid, sebacic acid and 1,10-decandiol such as those marketed under the name Acnacidol BG by Vincience and mixtures thereof.

Depigmentation agents

Non-limiting examples of depigmentation agents include alpha and beta arbutin, ferulic acid, lucinol and its derivatives, kojic acid and its derivatives, tranexamic acid and its derivatives. -ci, gentisic acid, homgentisic acid, methyl gentisate or homogentisate, dioic acid, calcium D panthetine sulfonate, lipoic acid, ellagic acid, vitamin B3, linoleic acid and its derivatives, certain compounds derived from plants such as chamomile, bearberry, aloes (vera, ferox, bardensis), blackberry, skullcap, water kiwi (Actinidia chinensis) marketed by Gattefosse, a root extract of Paeonia suffruticosa, such as that marketed by Ichimaru Pharcos under the name Liquid Botanpi B, an extract of brown sugar (Saccharum officinarum) such as an extract of molasses marketed by Taiyo Kagaku under the name Liquid Molasses, this list not being exhaustive. Specific depigmentation agents include alpha and beta arbutin, ferulic acid, kojic acid, resorsinol and their derivatives, calcium D panthetein sulfonate, lipoic acid, ellagic acid, vitamin B3, a water kiwi (Actinidia chinensis) marketed by Gattefosse, a root extract of Paeonia suffruticosa, such as that marketed by the company Ichimaru Pharcos under the name Botanpi Liquid B.

Anti-wrinkle agent

The term "anti-wrinkle agent" refers to a natural or synthetic compound producing a biological effect, such as the synthesis and/or increased activity of certain enzymes, when brought into contact with an area of wrinkled skin, this has the effect of effect of reducing the appearance of wrinkles and/or fine lines. Non-limiting examples of anti-wrinkle agents include: desquamating agents, anti-glycation agents, NO-synthase inhibitors, agents stimulating the synthesis of dermal or epidermal macromolecules, and/or preventing their degradation, agents for stimulating the proliferation of fibroblasts and /or keratinocytes, or to stimulate agents for reducing keratinocyte differentiation; muscle relaxants and/or dermo-relaxants, anti-free radical agents, and mixtures thereof. Examples of such compounds are: adenosine and its derivatives and retinoids other than retinol (as noted above, such as retinol palmitate), ascorbic acid and its derivatives such as magnesium ascorbyl phosphate. and ascorbyl glucoside; nicotinic acid and its precursors such as nicotinamide; ubiquinone; glutathione and precursors thereof such as L-2-oxothiazolidine-4-carboxylic acid, C-glycoside compounds and their derivatives as described in particular in document EP-1345919, in particular, C-beta -D-xylopyranoside-2-hydroxy-propane as described in particular in document EP-1345919, plant extracts including marine fennel and olive leaf extracts, as well as the plant and the hydrolysates thereof such as rice protein hydrolysates or soybean proteins; extracts of algae and in particular laminaria, bacterial extracts, sapogenins such as diosgenin and extracts of Dioscorea plants, in particular wild yam, comprising: α-hydroxy acids, β-hydroxy acids, such as salicylic acid and n-octanoyl-5-salicylic oligopeptides and pseudodipeptides and acyl derivatives thereof, particularly {2-[acetyl-(3-trifluoromethyl-phenyl)-amino]-3 acid -methyl-}acetic and lipopeptides marketed by the company SEDERMA under the brand names Matrixyl 500 and Matrixyl 3000; lycopene, manganese salts and magnesium salts, in particular gluconates, and mixtures thereof. In at least one case, the skin firming composition includes adenosine derivatives, such as non-phosphate adenosine derivatives such as in particular 2'-deoxyadenosine, 2',3'-adenosine isopropoylidene; toyocamycin, 1-methyladenosine, N-6-methyladenosine; adenosine N-oxide, 6-methylmercaptopurine riboside and 6-chloropurine riboside. Other derivatives include adenosine receptor agonists such as phenylisopropyl adenosine ("PIA"), 1-methylisoguanosine, N6-cyclohexyladenosine (CHA), N6-cyclopentyladenosine (CPA), 2-chloro-N6-cyclopentyladenosine, 2-chloroadenosine, N6-phenyladenosine, 2-phenylaminoadenosine, MECA, N 6-phenethyladenosine, 2-p-(2-carboxy-ethyl) phenethyl-amino-5'- -N-ethylcarboxamido adenosine (CGS-21680), N- ethylcarboxamidoadenosine (NECA), 5'(N-cyclopropyl)-carboxamidoadenosine, DPMA (PD 129.944) and metrifudil.

Various ingredients may be included in the cosmetic composition, for example, in an amount of about 0.01 to about 10% by weight, based on the total weight of the cosmetic composition. The total amount of the one or more miscellaneous ingredients may be from about 0.01 to about 8% by weight, from about 0.01 to about 5% by weight, from about 0.01 to about 3% by weight, from about 0.1 to about 10% by weight, from about 0.1 to about 8% by weight, from about 0.1 to about 5% by weight, from about 0.1 to about 3% by weight weight, from about 1 to about 10% by weight, from about 1 to about 8% by weight, from about 1 to about 5% by weight or from about 1 to about 3% by weight, based on the total weight of the cosmetic composition.

As already noted, the skin active agents may be included in the form of one or more of the various ingredients. Based on the total amount of skin active agents in the cosmetic compositions, if any, the total amount of skin active agents may be from more than zero to about 9% by weight, from more than zero to about 8% by weight, from more than zero to about 7% by weight, from more than zero to about 6% by weight, from more than zero to about 5% by weight, from more than zero to about 4% by weight, more than zero to about 3% by weight, more than zero to about 2% by weight; from about 10 ppm to about 10% by weight (100,000 ppm), from about 10 ppm to about 5% by weight (50,000 ppm), from about 10 ppm to about 2.5% by weight (25,000 ppm), from about 10 ppm to about 1 wt% (10,000 ppm), from about 10 ppm to about 0.5 wt% (5,000 ppm), from about 10 ppm to about 0.3 wt% (3,000 ppm ), from about 10 ppm to about 0.2 wt% (2,000 ppm), from about 10 ppm to about 0.1 wt% (1,000 ppm), from about 10 ppm to 500 ppm; from approximately 0.1 to approximately 10% by weight, from approximately 0.1 to approximately 5% by weight, approximately 0.1 to approximately 2.5% by weight, approximately 0.1 to approximately 1% by weight, from about 0.1 to about 0.5% by weight; from about 1 to about 10% by weight, from about 1 to about 8% by weight, from about 1 to about 6% by weight, from about 1 to about 5% by weight, from about 1 to about 4% by weight, from about 1 to about 3% by weight; from about 2 to about 10% by weight, from about 2 to about 8% by weight, from about 2 to about 6% by weight, from about 2 to about 5% by weight, from about 2 to about 4% by weight; from about 3 to about 10% by weight, from about 3 to about 8% by weight, from about 3 to about 6% by weight, from about 3 to about 5% by weight; from about 4 to about 10% by weight, from about 4 to about 8% by weight or from about 4 to about 6% by weight, based on the total weight of the cosmetic composition.

In one embodiment, the cosmetic compositions of the present disclosure may optionally include one or more phenolic or polyphenolic active compounds, for example, baicalin. However, in one embodiment, the cosmetic compositions may be free or essentially free of phenolic or polyphenolic active compounds, in particular, baicalin.

(h) Fatty compounds

The cosmetic compositions may optionally include one or more fatty compounds. The term “fatty compounds” is interchangeable with “fat”. Fatty compounds are known as compounds that are not soluble (or only very weakly soluble) in water; they are hydrophilic and are often solubilized in organic solvents. They include substances such as oils, fats, waxes, hydrocarbons, fatty alcohols, fatty acids, fatty esters, etc. Silicones are not considered fatty compounds according to this disclosure. Non-limiting examples of useful fatty compounds include oils, waxes, alkanes (paraffins), fatty alcohols, fatty acids, fatty esters, triglyceride compounds, lanolin, hydrocarbons, derivatives thereof and mixtures thereof. Fatty compounds are described by the International Federation Societies of Cosmetic Chemists, for example, in Cosmetic Raw Material Analysis and Quality, Volume I : Hydrocarbons, Glycerides, Waxes and Other Esters (Redwood Books, 1994), which is incorporated herein at reference title in its entirety.

Non-limiting examples of fatty compounds include oils, mineral oil, alkanes (paraffins), fatty acids, fatty alcohol derivatives, fatty acid derivatives, fatty alcohol esters, hydroxy-substituted fatty acids, waxes, triglyceride compounds , lanolin and a mixture thereof.

Fatty alcohol derivatives

The fatty compounds may include one or more fatty alcohol derivatives, which are different from fatty alcohols (component (d)). Fatty alcohol derivatives include fatty esters derived from one or more fatty alcohols. Fatty alcohol derivatives also include alkoxylated fatty alcohols, for example, having about 1 to about 100 moles of an alkylene oxide per mole of alkoxylated fatty alcohol. For example, alkoxylated fatty alcohols can be alkoxylated with about 1 to about 80 moles, about 2 to about 50, about 5 to about 45 moles, about 10 to about 40 moles, or 15 to about 35 moles, including all ranges. and subranges between these ranges, of one alkylene oxide per mole of alkoxylated fatty alcohol.

As examples of fatty alcohols, steareth (e.g., steareth-2, steareth-20, and steareth-21), laureth (e.g., laureth-4, and laureth-12), ceteth (e.g. , ceteareth-10 and ceteareth-20) and ceteareth (e.g. ceteareth-2, ceteareth-10 and ceteareth-20) are mentioned. In at least one case, the one or more alkoxylated fatty alcohols include 20-steareth. In certain cases, the one or more alkoxylated fatty alcohols may be exclusively 20-steareth.

Other fatty alcohol derivatives which may possibly be suitable include methyl stearyl ether; 2-ethylhexyl dodecyl ether; stearyl acetate; cetyl propionate; the ceteth series of compounds, such as ceteth-1 to ceteth-45, which are ethylene glycol ethers of cetyl alcohol, in which the numerical designation indicates the number of ethylene glycol moieties present; series of steareth compounds such as steareth-1 to 10, which are ethylene glycol ethers of stearyl alcohol, in which the numerical designation indicates the number of ethylene glycol moieties present; ceteareth 1 to ceteareth-10, which are ethylene glycol ethers of cetearyl alcohol, namely a mixture of fatty alcohols containing predominantly cetyl and stearyl alcohol, in which the numerical designation indicates the number of fractions of ethylene glycol present; the C1-C30 alkyl ethers of the ceteth, steareth and ceteareth compounds described above; polyoxyethylene ethers of branched alcohols such as octyldodecyl alcohol, dodecylpentadecyl alcohol, hexyldecyl alcohol; polyoxyethylene ethers of behenyl alcohol; PPG ethers such as PPG-9-steareth-3, PPG-11 stearyl ether, PPG8-ceteth-1 and PPG-10 cetyl ether; and a mixture of these.

Fatty acids

In certain cases, the fatty compounds may be chosen from fatty acids, fatty acid derivatives, fatty acid esters, hydroxyl-substituted fatty acids and alkoxylated fatty acids. The fatty acids may be straight or branched chain acids and/or may be saturated or unsaturated. Non-limiting examples of fatty acids include diacids, triacids and other multiple acids such as salts of these fatty acids. For example, the fatty acid may optionally include or be chosen from lauric acid, palmitic acid, stearic acid, behenic acid, arichidonic acid, oleic acid, isostearic acid, sebacic acid and a mixture of those. -this. In some cases, the fatty acids are selected from the group consisting of palmitic acid, stearic acid and a mixture thereof.

Non-limiting examples of polyglycerol esters of fatty acids include those of the following formula:

in which the average value of n is approximately 3 and R¹,R²and R³can each independently be a fatty acid moiety or a hydrogen atom, provided that at least one of R¹,R²and R³or a fatty acid fraction. For example, R¹,R²and R³can be saturated or unsaturated, linear or branched, and have a length of C₁-VS₄₀, VS₁-VS₃₀, VS₁-VS₂₅, or C₁-VS₂₀, VS₁-VS_16,Or VS₁-VS₁₀.

Fatty acid derivatives are defined here as including fatty acid esters of fatty alcohols as defined above, fatty acid esters of fatty alcohol derivatives as defined above when such alcohol derivatives fatty acids have an esterifiable hydroxyl group, fatty acid esters of alcohols other than the fatty alcohols and fatty alcohol derivatives described above, hydroxy-substituted fatty acids, and a mixture thereof. Non-limiting examples of fatty acid derivatives include ricinoleic acid, glycerol monostearate, 12-hydroxy stearic acid, ethyl stearate, cetyl stearate, cetyl palmitate, polyoxyethylene cetyl stearate ether, polyoxyethylene stearyl ether, polyoxyethylene lauryl ether stearate, ethylene glycol monostearate, polyoxyethylene monostearate, polyoxyethylene distearate, propylene glycol monostearate, propylene glycol distearate, trimethylolpropane distearate, sorbitan, polyglyceryl stearate, dimethyl sebacate, PEG-15 cocoate, PPG-15 stearate, glyceryl monostearate, glyceryl distearate, glyceryl Trèsstearate, PEG-8 laurate, PPG-2 isostearate, PPG-9 laurate and a mixture thereof. Herein, the use of glycerol monostearate, 12-hydroxy stearic acid and a mixture thereof is preferred.

Fatty alcohols

The expression “fatty alcohol” means an alcohol comprising at least one hydroxyl group (OH), and comprising at least 8 carbon atoms, and which is neither oxyalkylenated (in particular, neither oxyalkylenated nor oxypropylenated), nor glycerol. Fatty alcohols can be represented by the formula: R-OH, in which R denotes a saturated (alkyl) or unsaturated (alkenyl), linear or branched, group comprising from 8 to 40 carbon atoms, preferably from 10 to 30 carbon atoms, more preferably 12 to 24 carbon atoms, and even more preferably 14 to 22 carbon atoms.

Fatty alcohol(s) can be liquid or solid. In certain cases, it is preferable for the cosmetic compositions to include at least one solid fatty alcohol. Solid fatty alcohols that may be used include those that are solid at room temperature and atmospheric pressure (25°C, 780 mmHg), and are insoluble in water, i.e., have a water solubility of less than 1% by weight, preferably less than 0.5% by weight, at 25°C, 1 atm.

Solid fatty alcohols can be represented by the formula: R-OH, in which R denotes a linear alkyl group, optionally substituted with one or more hydroxyl groups, comprising from 8 to 40 carbon atoms, preferably from 10 to 30 atoms carbon, more preferably, 12 to 24 carbon atoms, and even more preferably, 14 to 22 carbon atoms.

Non-limiting examples of useful fatty alcohols include lauryl alcohol or lauryl alcohol (1-dodecanol); palmyristic or myristyl alcohol (1-tetradecanol); cetyl alcohol (1-hexadecanol); stearyl alcohol (1-octadecanol); arachidyl alcohol (1-eicosanol); behenyl alcohol (1-docosanol); lignoceryl alcohol (1-tetracosanol); cerylic alcohol (1-hexacosanol); montanylic alcohol (1-octacosanol); myricyl alcohol (1-triacontanol) and mixtures thereof.

In some embodiments, the one or more fatty alcohols have 12 to 24 carbon atoms. Specific non-limiting examples include cetyl alcohol, stearyl alcohol, cetearyl alcohol, behenyl alcohol, lauryl alcohol, myristic or myristyl alcohol, arachidyl alcohol, lignoceryl alcohol or mixtures of these.

Preferably, the cosmetic composition includes one or more solid fatty alcohols, for example, chosen from cetyl alcohol, stearyl alcohol, behenyl alcohol and mixtures thereof, preferably cetyl alcohol, behenyl alcohol, cetearyl alcohol and mixtures thereof.

Liquid fatty alcohols, especially those containing C10-C34, preferably have branched carbon chains and/or have one or more, preferably 1 to 3, double bonds. They are preferably branched and/or unsaturated (C=C double bond) and contain 12 to 40 carbon atoms.

Liquid fatty alcohols can be represented by the formula: R-OH, in which R denotes a branched C12-C24 alkyl group or an alkenyl group (comprising at least one C=C double bond in C12-C24), R optionally being substituted with one or more hydroxy groups. Preferably, the liquid fatty alcohol is a branched saturated alcohol. Preferably, R does not contain a hydroxyl group. These include oleic alcohol, linoleic alcohol, linolenic alcohol, isocetyl alcohol, isostearyl alcohol, 2-octyl-1-dodecanol, 2-butyloctanol, 2-hexyl-1- decanol, 2-decyl-1-tetradecanol, 2-tetradecyl-1-cetanol and mixtures thereof. Preferably, the liquid fatty alcohol is 2-octyl-1-dodecanol.

In certain cases, the cosmetic compositions include one or more fatty alcohols selected from decyl alcohol, undecyl alcohol, dodecyl, myristyl, cetyl alcohol, stearyl alcohol, cetearyl alcohol, isostearyl alcohol, isocetyl alcohol, behenyl alcohol, linalool, oleyl alcohol, myricyl alcohol and a mixture thereof. In some cases, the cosmetic compositions preferably include cetyl alcohol, behenyl alcohol and cetearyl alcohol.

Raincoats

The fatty compounds may, in certain cases, include or be chosen from one or more waxes. Non-limiting examples of waxes in this category include, for example, synthetic wax, ceresin, paraffin, ozokerite, polyethylene waxes, illipé butter, beeswax, carnauba wax, microcrystalline wax, lanolin, lanolin derivatives, candelilla wax, cocoa butter, shellac wax, spermaceti, bran wax, kapok wax, sugarcane wax, wax lignite, whale wax, laurel berry wax, acacia decurrent flower wax, vegetable waxes (such as sunflower seed waxes (helianthus annuus), carnauba wax, candelilla wax, from ouricury or Japan or cork or sugar cane fiber waxes) or a mixture of these.

Oils

In some cases, the fatty compounds may include or may be selected from one or more oils. Suitable oils include, but are not limited to, natural oils, such as coconut oil; hydrocarbons, such as mineral oil and hydrogenated polyisobutene; fatty alcohols, such as octyldodecanol; esters, such as C ₁₂ -C ₁₅ alkyl benzoate; diesters, such as propylene dipelarganate; and triesters, such as glyceryl trioctanate. Non-limiting examples of oils which may optionally be included in the cosmetic compositions include isotridecyl isononanoate, PEG-4 diheptanoate, isostearyl neopentanoate, tridecyl neopentanoate, cetyl octanoate, cetyl palmitate, cetyl ricinoleate, cetyl stearate, cetyl myristate, coco-dicaprylate/caprate, decyl isostearate, isodecyl oleate, isodecyl neopentanoate, isohexyl neopentanoate , octyl palmitate, dioctyl malate, tridecyl octanoate, myristyl myristate, octododecanol, or combinations of octyldodecanol, acetylated lanolin alcohol, cetyl acetate, isododecanol, polyglyceryl-3-diisostearate , castor oil, lanolin and lanolin derivatives, triisocetyl citrate, sorbitan sesquioleate, C ₁₀ -C ₁₈ triglycerides, caprylic/capric triglycerides, coconut oil, corn oil, cottonseed oil, glyceryl triacetyl hydroxystearate, ricinoleate glyceryl triacetanoate, glyceryl trioactanoate, hydrogenated castor oil, flaxseed oil, vision oil, olive oil, palm oil, illipé butter, rapeseed oil, soybean oil, sunflower oil, tallow, tricaprin , trihydroxystearin, triisostearin, trilaurine, trilinolein, trimyristin, triolein, tripalmitin, sadearin, walnut oil, wheat germ oil, cholesterol, or combinations thereof.

In certain embodiments, the cosmetic composition may include one or more fatty compounds chosen from fatty esters (such as isonolyl isononanoate), polyolefins (such as petroleum jelly), waxes, squalane, squalene, hydrogenated polyisobutene, hydrogenated polydecene, polybutylene, mineral oil, pentahydrosqualene, plant and/or vegetable oil, hydrocarbon-based oils (such as isohexadecane), or a mixture thereof this.

Generally, the amount of the one or more fatty compounds in the cosmetic compositions may range from about 5% by weight to about 20% by weight, based on the total weight of the cosmetic composition. In various embodiments, the amount of the one or more fatty compounds in the cosmetic compositions may range from about 5 to about 15% by weight, from about 5 to about 12% by weight, from about 6 to about 20% by weight. weight, from about 6 to about 15% by weight, from about 6 to about 12% by weight, based on the total weight of the cosmetic composition.

Stability

The cosmetic compositions of the present disclosure are stable. For example, in one embodiment, the cosmetic compositions do not visually exhibit phase separation or form visibly observable particles for at least 2 weeks, 4 weeks and/or 8 weeks when stored at 4 ^o C. , 25 ^o C, 37 ^o C and/or 45 ^o C.

In another embodiment, the cosmetic compositions do not visually exhibit phase separation or form visibly observable particles during at least 10 freeze-thaw test cycles, wherein the freeze-thaw test consists of placing the cosmetic composition in a stability chamber and subjecting it to a temperature fluctuation at intervals of 12 hours, for a first interval of 12 hours at - 20 ^o C then a second interval of 12 hours at 25 ^o C .

In one embodiment, the viscosity of the cosmetic compositions does not change by more than 20%, 15%, 10% or 5%, for at least 2 weeks, 4 weeks and/or 8 weeks in stock at 4 ^o C, 25 ^o C, 37 ^o C and/or 45 ^o C.

Viscosity

In general, the cosmetic compositions herein have a viscosity of about 5,000 to about 200,000 Pa.s at 25°C and a shear rate of 1 s ^-1 at 25°C. However, the cosmetic compositions may have a viscosity of approximately 10,000 to approximately 200,000 Pa.s, of approximately 10,000 to approximately 180,000 Pa.s, of approximately 10,000 to approximately 150,000 Pa.s, of approximately 10,000 to approximately 120,000 Pa.s, from approximately 10,000 to approximately 100,000 Pa.s, from approximately 10,000 to approximately 80,000 Pa.s, from approximately 15,000 to approximately 200,000 Pa.s, from approximately 15,000 to approximately 180,000 Pa.s, from approximately 15,000 to approximately 150,000 Pa.s, from approximately 15,000 to approximately 120,000 Pa.s, from approximately 15,000 to approximately 100,000 Pa.s. s, from approximately 15,000 to approximately 80,000 Pa.s, from approximately 20,000 to approximately 200,000 Pa.s, from approximately 20,000 to approximately 180,000 Pa.s, from approximately 20,000 to approximately 150,000 Pa.s, from approximately 20,000 to approximately 120,000 Pa.s, from approximately 20,000 to approximately 100,000 Pa.s, from approximately 20,000 to approximately 80,000 Pa.s, from approximately 30,000 to approximately 200,000 Pa.s, from approximately 30,000 to approximately 180,000 Pa.s, from approximately 30,000 to approximately 150,000 Pa.s, from approximately 30,000 to approximately 120,000 Pa.s, from approximately 30,000 at approximately 100,000 Pa.s, from approximately 30,000 to approximately 80,000 Pa.s, from approximately 35,000 to approximately 200,000 Pa.s, from approximately 35,000 to approximately 180,000 Pa.s, from approximately 35,000 to approximately 150,000 Pa.s, from approximately 35,000 to approximately 120,000 Pa.s, from approximately 35,000 to approximately 100,000 Pa.s or from approximately 35,000 to approximately 80,000 Pa.s at 25 °C, and a shear rate of 1 s ^-1 at 25 °C.

Viscosity measurements can be made, for example, using a Brookfield viscometer/rheometer using a t-bar spindle at a speed of 5, 10, 15 and/or 20 rpm. An RVDV-II+Pro viscometer with RheocalcT software can be used for automated instrument control and data acquisition. The test temperature is maintained at 25°C using a Brookfield TC-502P programmable refrigerated bath. From its original container, a sample is transferred to a 120 mL glass jar and then subjected to testing.

Processes

The present disclosure relates to methods of treating skin. The methods include applying a cosmetic composition according to the present disclosure, optionally allowing the cosmetic composition to sit on the skin for a period of time. Cosmetic compositions are usually applied directly to the skin by hand or using a tissue. The skin may optionally be washed or rinsed before application. The skin treatment process may be performed only once per day or may be performed multiple times. For example, the skin treatment method can be carried out once a day, twice a day, once a week, twice a week for an extended period of time, for example, for about 1, 2, 3, 4, 5 or 6 months up to 1 year or more. In various embodiments, the methods relate to strengthening or improving the skin's natural lipid barrier by treating dry and/or aging skin; maintaining and/or improving the water balance of the skin; and/or improvement in the appearance of the skin.

The present disclosure relates to methods of stabilizing a cosmetic composition containing large quantities of hydroxypropyl tetrahydropyrantriol. This process includes incorporating hydroxypropyl tetrahydropyrantriol into the compositions of the present disclosure. The amounts of hydroxypropyl tetrahydropyrantriol that may be incorporated are the amounts set forth throughout this disclosure.

Kits

The cosmetic compositions of the present disclosure may be provided in a kit, for example, a kit comprising an individually contained cosmetic composition according to the present disclosure and one or more separately contained cosmetic compositions. In one embodiment, the one or more separately contained compositions may be a complementary composition according to the present disclosure or may be a different composition. The cosmetic compositions may be contained separately in different cartridges, which are included in a dispensing apparatus/device. In other words, the kit may be a dispensing apparatus/device comprising a plurality of cartridges in which the compositions are contained. The kit (or apparatus/device) may optionally dispense the cosmetic composition of the present disclosure and separately dispense the one or more separately contained compositions. In various embodiments, the compositions may be dispensed individually or simultaneously, and may optionally be mixed (or unmixed) with each other before being dispensed. In one embodiment, the various compositions are not mixed with each other before being distributed. Useful systems, cartridges and dispensing apparatus/devices are disclosed in US Patent Nos. 9,968,177 and 9,808,071; publications of US patent applications. No. 2021/0236390, 2021/0235849 and 2021/0236863; and in US Series No. 17/162,555, all of which are incorporated herein by reference in their entirety.

Embodiments

In certain embodiments, the cosmetic composition comprises or consists of:

(a) about 10 to about 50 weight percent, preferably about 15 to about 40 weight percent, more preferably about 25 to about 40 weight percent of hydroxypropyl tetrahydropyrantriol;

(b) about 10 to about 50 weight percent, preferably about 15 to about 40 weight percent, more preferably about 20 to about 30 weight percent of one or more silicone oils, preferably of one or more silicone oils chosen from dimethicone, dimethiconol, cyclopentasiloxane, cyclomethicone, cyclotetrasiloxane, cyclohexasiloxane, cycloheptasiloxane, decamethylcyclopentasiloxane, cyclotetrasiloxane, cyclotrisiloxane, capryldimethicone, caprylyltrimethicone, caprylylmethicone, cetearylmethicone, hexadecylmethic one, hexylmethicone, laurylmethicone, myristylmethicone, phenylmethicone, stearylmethicone, stearyldimethicone , behenyldimethicone, trifluoropropylmethicone, cetyldimethicone, polyphenylmethylsiloxane, dimethylpolysiloxane, methylphenylpolysiloxane, methyltrimethicone, diphenylsiloxyphenyl trimethicone, phenyltrimethicone, and mixtures thereof, more preferably, dimethicone;

(c) about 0.1 to about 10 weight percent, preferably about 0.1 to about 5 weight percent, more preferably about 1 to about 5 weight percent of one or more non-emulsifying silicone elastomers , preferably chosen from crosslinked polymers of dimethicone, crosslinked polymers of (dimethicone/phenyl divinyl methicone), crosslinked polymers of (dimethicone/vinyl dimethicone/methicone), crosslinked polymers of (dimethicone/vinyl dimethicone), and crosslinked polymers of (diphenyl dimethicone /vinyl diphenyl dimethicone/silsesquioxane), and mixtures thereof, more preferably selected from cross-linked polymer of dimethicone, cross-linked polymer of vinyl dimethicone, cross-linked polymer of dimethicone/vinyl dimethicone, cross-linked polymer of dimethicone-3, polysilicone-11 , and mixtures thereof;

(d) about 0.1 to about 10% by weight, preferably about 0.1 to about 5% by weight, of one or more dimethicone copolyol emulsifiers, comprising at least one oxyethylene group and at least one group oxypropylene, preferably one or more dimethicone emulsifiers C8-C22 alkyl copolyol comprising at least one oxyethylene group and at least one oxypropylene group, for example, bis-PEG/PPG-14/14 dimethicone, bis- isobutyl PEG/PPG-10/7 dimethicone, bis-PEG/PPG-18/6 dimethicone; bis-PEG/PPG-20/20 dimethicone, bis-PEG/PPG-16/16 dimethicone, cetyl PEG/PPG-15/16 butyl ether dimethicone, cetyl PEG/PPG-15/15 butyl ether dimethicone, cetyl PEG/PPG -7/3 dimethicone, cetyl PEG/PPG-10/1 dimethicone, dimethicone PEG/PPG-7/4 phosphate, dimethicone PEG/PPG-12/4 phosphate, PEG/PPG-28/21 acetate dimethicone, PEG/PPG- 22/22 butyl ether dimethicone, PEG/PPG-23/23 butyl ether dimethicone, PEG/PPG-24/18 butyl ether dimethicone, PEG/PPG-3/10 dimethicone, PEG/PPG-4/12 dimethicone, PEG/PPG -6/11 dimethicone, PEG/PPG-8/14 dimethicone, PEG/PPG-12/16 dimethicone, PEG/PPG-12/18 dimethicone, PEG/PPG-14/4 dimethicone, PEG/PPG-15/5 dimethicone , PEG/PPG-15/15 dimethicone, PEG/PPG-16/2 dimethicone, PEG/PPG-16/8 dimethicone, PEG/PPG-17/18 dimethicone, PEG/PPG-18/12 dimethicone, PEG/PPG- 19/19 dimethicone, PEG/PPG-20/6 dimethicone, PEG/PPG-20/15 dimethicone, PEG/PPG-20/20 dimethicone, PEG/PPG-20/29 dimethicone, PEG/PPG-22/23 dimethicone, PEG/PPG-22/24 dimethicone, PEG/PPG-25/25 dimethicone, PEG/PPG-27/27 dimethicone, PEG/PPG-30/10 dimethicone, PEG/PPG-10/3 oleyl ether dimethicone, and mixtures of these, preferably one of the one or more dimethicone copolyol emulsifiers is a dimethicone/PEG-10/15 copolymer;

wherein the weight ratio of (c) to (d) is from about 5:1 to about 1:5, preferably from about 4:1 to about 1:4, more preferably from about 3: 1 to about 1:3, and even more preferably, from about 2:1 to about 1:2;

(e) about 10 to about 50 weight percent, preferably about 15 to about 45 weight percent or more preferably about 25 to about 40 weight percent water; And

(f) about 0.1 to about 20 weight percent, preferably about 0.1 to about 15 weight percent, more preferably about 1 to about 10 weight percent of one or more water-soluble solvents, preferably , one or more water-soluble solvents chosen from glycerin, C ₁ -C ₅ monoalcohols, polyols (polyhydric alcohols), glycols and a mixture of these, more preferably, chosen from propylene glycol, butylene glycol, pentylene glycol, dipropylene glycol, ethanol, isopropanol, tert-butyl alcohol and mixtures thereof;

(g) optionally, one or more various ingredients, for example various ingredients chosen from various emulsifiers/surfactants other than the dimethicone copolyol emulsifiers of (d), preservatives, perfumes, acidity correctors, salts, antioxidants, vitamins , botanical extracts, UV filter agents, proteins, protein hydrolysates and/or isolates, hydrotropes, nacreous agents, fillers, dyes, mattifying agents, other skin active agents, buffers, and mixtures thereof, preferably, the one or more miscellaneous ingredients include one or more other active agents for the skin, wherein optionally, the one or more miscellaneous ingredients may be in an amount of from about 0.01 to about 10% by weight, preferably , from about 0.1 to about 8% by weight, more preferably, from about 1 to about 6% by weight;

wherein the composition is in the form of a water-in-silicone emulsion and all weight percentages are based on the total weight of the composition.

The cosmetic compositions of the present disclosure are stable. For example, in one embodiment, the cosmetic compositions do not visually exhibit phase separation or form visibly observable particles for at least 2 weeks, 4 weeks and/or 8 weeks when stored at 4 ^o C. , 25 ^o C, 37 ^o C and/or 45 ^o C.

In another embodiment, the cosmetic compositions do not visually exhibit phase separation or form visibly observable particles during at least 10 freeze-thaw test cycles, wherein the freeze-thaw test includes placing the cosmetic composition in a stability chamber and subjecting it to a temperature fluctuation at intervals of 12 hours, for a first interval of 12 hours at - 20 ^o C followed by a second interval of 12 hours at 25 ^o vs.

In one embodiment, the viscosity of the cosmetic compositions does not change by more than 20%, 15%, 10% or 5%, for at least 2 weeks, 4 weeks and/or 8 weeks when stored at 4 ^o C, 25 ^o C, 37 ^o C and/or 45 ^o C.

The cosmetic compositions preferably have a viscosity of about 5,000 to about 200,000 Pa.s at 25°C, and a shear rate of 1 s ^-1 at 25°C. However, in other embodiments, the compositions have a viscosity of about 10,000 to about 200,000 Pa.s, about 10,000 to about 180,000 Pa.s, about 10,000 to about 150,000 Pa.s, from approximately 10,000 to approximately 120,000 Pa.s, from approximately 10,000 to approximately 100,000 Pa.s, from approximately 10,000 to approximately 80,000 Pa.s, from approximately 15,000 to approximately 200,000 Pa.s, from approximately 15,000 to approximately 180,000 Pa.s, from approximately 15,000 to approximately 150,000 Pa.s, from approximately 15,000 to approximately 120,000 Pa.s, from approximately 15,000 at approximately 100,000 Pa.s, from approximately 15,000 to approximately 80,000 Pa.s, from approximately 20,000 to approximately 200,000 Pa.s, from approximately 20,000 to approximately 180,000 Pa.s, from approximately 20,000 to approximately 150,000 Pa.s, from approximately 20,000 to approximately 120,000 Pa.s, from approximately 20,000 to approximately 100,000 Pa.s, from approximately 20,000 to approximately 80,000 Pa.s, d 'approximately 30,000 to approximately 200,000 Pa.s, from approximately 30,000 to approximately 180,000 Pa.s, from approximately 30,000 to approximately 150,000 Pa.s, from approximately 30,000 to approximately 120,000 Pa.s , from approximately 30,000 to approximately 100,000 Pa.s, from approximately 30,000 to approximately 80,000 Pa.s, from approximately 35,000 to approximately 200,000 Pa.s, from approximately 35,000 to approximately 180,000 Pa.s .s, from approximately 35,000 to approximately 150,000 Pa.s, from approximately 35,000 to approximately 120,000 Pa.s, from approximately 35,000 to approximately 100,000 Pa.s or from approximately 35,000 to approximately 80 000 Pa.s at 25°C, and a shear rate of 1 s ^-1 at 25°C.

In various embodiments, the cosmetic composition comprises or consists of:

(has about 10 to about 50 weight percent, preferably about 15 to about 40 weight percent, more preferably about 25 to about 40 weight percent of hydroxypropyl tetrahydropyrantriol;

(b) about 10 to about 50 weight percent, preferably about 15 to about 40 weight percent, more preferably about 20 to about 30 weight percent of one or more silicone oils, preferably one or more silicone oils selected from dimethicone, dimethiconol, cyclopentasiloxane, cyclomethicone, phenyl trimethicone, and mixtures thereof, more preferably dimethicone;

(c) about 0.1 to about 10 weight percent, preferably about 0.1 to about 5 weight percent, more preferably about 1 to about 5 weight percent of one or more non-emulsifying silicone elastomers , in which the one or more non-emulsifying silicone elastomers are chosen from a crosslinked polymer of dimethicone, a crosslinked polymer of vinyl dimethicone, a crosslinked polymer of dimethicone/vinyl dimethicone, a crosslinked copolymer of dimethicone-3, a polysilicone-11, and mixtures thereof, preferably, a cross-linked polymer of dimethicone;

(d) about 0.1 to about 10 weight percent, preferably about 0.1 to about 5 weight percent, of one or more dimethicone copolyol emulsifiers comprising at least one oxyethylene group and at least one oxypropylene group , preferably, C8-C22 alkyl copolyol dimethicone emulsifiers comprising at least one oxyethylene group and at least one oxypropylene group, for example, bis-PEG/PPG-14/14 dimethicone, bis-isobutyl PEG/PPG- 10/7 dimethicone copolymer, bis-PEG/PPG-18/6 dimethicone; bis-PEG/PPG-20/20 dimethicone, bis-PEG/PPG-16/16 dimethicone, cetyl PEG/PPG-15/16 butyl ether dimethicone, cetyl PEG/PPG-15/15 butyl ether dimethicone, cetyl PEG/PPG -7/3 dimethicone, cetyl PEG/PPG-10/1 dimethicone, dimethicone PEG/PPG-7/4 phosphate, dimethicone PEG/PPG-12/4 phosphate, PEG/PPG-28/21 acetate dimethicone, PEG/PPG- 22/22 butyl ether dimethicone, PEG/PPG-23/23 butyl ether dimethicone, PEG/PPG-24/18 butyl ether dimethicone, PEG/PPG-3/10 dimethicone, PEG/PPG-4/12 dimethicone, PEG/PPG -6/11 dimethicone, PEG/PPG-8/14 dimethicone, PEG/PPG-12/16 dimethicone, PEG/PPG-12/18 dimethicone, PEG/PPG-14/4 dimethicone, PEG/PPG-15/5 dimethicone , PEG/PPG-15/15 dimethicone, PEG/PPG-16/2 dimethicone, PEG/PPG-16/8 dimethicone, PEG/PPG-17/18 dimethicone, PEG/PPG-18/12 dimethicone, PEG/PPG- 19/19 dimethicone, PEG/PPG-20/6 dimethicone, PEG/PPG-20/15 dimethicone, PEG/PPG-20/20 dimethicone, PEG/PPG-20/29 dimethicone, PEG/PPG-22/23 dimethicone, PEG/PPG-22/24 dimethicone, PEG/PPG-25/25 dimethicone, PEG/PPG-27/27 dimethicone, PEG/PPG-30/10 dimethicone, PEG/PPG-10/3 oleyl ether dimethicone, and mixtures of these, preferably one of the one or more dimethicone copolyol emulsifiers is a dimethicone/PEG-10/15 cross-linked polymer;

wherein the weight ratio (c) to (d) is about 5:1 to about 1:5, preferably about 4:1 to about 1:4, more preferably about 3:1 to about 1:3, and even more preferably, from about 2:1 to about 1:2;

(e) about 10 to about 50 weight percent, preferably about 15 to about 45 weight percent, or more preferably about 25 to about 40 weight percent water; And

(f) about 0.1 to about 20 weight percent, preferably about 0.1 to about 15 weight percent, more preferably about 1 to about 10 weight percent of one or more water-soluble solvents, preferably , one or more water-soluble solvents chosen from glycerin, C ₁ -C ₅ monoalcohols, polyols (polyhydric alcohols), glycols and a mixture of these, more preferably, chosen from propylene glycol, butylene glycol, pentylene glycol, dipropylene glycol, ethanol, isopropanol, tert-butyl alcohol and mixtures thereof;

(g) about 0.01 to about 10 weight percent, preferably about 0.1 to about 8 weight percent, more preferably about 1 to about 6 weight percent of one or more miscellaneous ingredients, wherein at least one of the one or more miscellaneous ingredients is another skin active agent, preferably a madecassoside;

wherein the composition is preferably a water-in-silicone emulsion and all weight percentages are based on the total weight of the composition.

The cosmetic compositions of the present disclosure are stable. For example, in one embodiment, the cosmetic compositions do not visually exhibit phase separation or form visibly observable particles for at least 2 weeks, 4 weeks and/or 8 weeks when stored at 4 ^o C. , 25 ^o C, 37 ^o C and/or 45 ^o C.

In another embodiment, the cosmetic compositions do not visually exhibit phase separation or form visibly observable particles during at least 10 freeze-thaw test cycles, wherein the freeze-thaw test consists of placing the cosmetic composition in a stability chamber and subjecting it to a temperature fluctuation at intervals of 12 hours, for a first interval of 12 hours at - 20 ^o C then a second interval of 12 hours at 25 ^o C .

In one embodiment, the viscosity of the cosmetic compositions does not change by more than 20%, 15%, 10% or 5%, for at least 2 weeks, 4 weeks and/or 8 weeks when stored at 4 ^o C, 25 ^o C, 37 ^o C and/or 45 ^o C.

The cosmetic compositions preferably have a viscosity of about 5,000 to about 200,000 Pa.s at 25°C, and a shear rate of 1 s ^-1 at 25°C. However, in other embodiments, the compositions have a viscosity of about 10,000 to about 150,000 Pa.s, about 10,000 to about 120,000 Pa.s, about 10,000 to about 100,000 Pa.s, from approximately 10,000 to approximately 80,000 Pa.s, from approximately 15,000 to approximately 200,000 Pa.s, from approximately 15,000 to approximately 180,000 Pa.s, from approximately 15,000 to approximately 150,000 Pa.s, from approximately 15,000 to approximately 120,000 Pa.s, from approximately 15,000 to approximately 100,000 Pa.s, from approximately 15,000 to approximately 80,000 Pa.s, from approximately 20,000 at approximately 200,000 Pa.s, from approximately 20,000 to approximately 180,000 Pa.s, from approximately 20,000 to approximately 150,000 Pa.s, from approximately 20,000 to approximately 120,000 Pa.s, from approximately 20,000 to approximately 100,000 Pa.s, from approximately 20,000 to approximately 80,000 Pa.s, from approximately 30,000 to approximately 200,000 Pa.s, from approximately 30,000 to approximately 180,000 Pa.s, d 'approximately 30,000 to approximately 150,000 Pa.s, from approximately 30,000 to approximately 120,000 Pa.s, from approximately 30,000 to approximately 100,000 Pa.s, from approximately 30,000 to approximately 80,000 Pa.s , from approximately 35,000 to approximately 200,000 Pa.s, from approximately 35,000 to approximately 180,000 Pa.s, from approximately 35,000 to approximately 150,000 Pa.s, from approximately 35,000 to approximately 120,000 Pa.s .s, from about 35,000 to about 100,000 Pa.s or from about 35,000 to about 80,000 Pa.s at 25 °C, and a shear rate of 1 s ^-1 at 25 °C.

Examples

Since various changes could be made in the methods described above without departing from the scope of the invention, it is understood that all of the material contained in the description above and in the examples below should be interpreted as illustrative and not in a limiting sense.

The following examples are intended to be non-restrictive and explanatory only. The quantities of ingredients in the compositions/formulas indicated below are expressed in % by weight, based on the total weight of the composition.

Example 1

(Compositions) of the invention Comparisons HAS B C-1 C-2 (has) Active HYDROXYPROPYL TETRAHYDROPYRANTRIOL 30 30 30 30 (b) Silicone oil DIMETHICON 25.1 25.1 25.1 25.1 (vs) Non-emulsifying silicone elastomer DIMETHICONE CROSS-LINKED POLYMER 2 2 2 (d) Dimethicone copolyol emulsifier CETYL PEG/PPG-10/1 DIMETHICONE 1.5 1.9 1.5 Report (c):(d) 1.3:1 1.1:1 SO SO (f) Water-soluble solvent PROPYLENE GLYCOL 3.4 3.4 3.4 3.4 (g) Various emulsifiers/surfactants, salts, preservatives, acidity regulators, perfumes, colorants, antioxidants, chelating agents and/or extracts, etc. ≤ 4 ≤ 4 ≤ 4 ≤ 4 (e) WATER 35.4 35 37.3 36.9 Stability O O NOT* NOT*

* Comparative compositions C-1 and C-2 did not form emulsions.

Example 2

(Stability test)

The compositions of Example 1 were subjected to stability studies and visually evaluated for phase separation and examined under a microscope for particle formation. The visual color change of the compositions was also evaluated. The compositions were examined during the initial manufacture of the composition (T ₀ ). The compositions were evaluated again after 10 days of freezing-thawing testing. The compositions were placed in a stability chamber and subjected to temperature fluctuation at 12 hour intervals. For 12 hours, the compositions were maintained at – 20 ^o C. For the next 12 hours, the compositions were maintained at 25 ^o C. The cycle was repeated 10 times (for 10 days).

Separately, the compositions of Example 1 were evaluated after 4 weeks (1 month) of storage at 4 ^o C, 25 ^o C, 37 ^o C and 45 ^o C and again after 8 weeks (2 months ) at 4 ^o C, 25 ^o C, 37 ^o C and 45 ^o C and assessed visually for phase separation and examined under a microscope for particle formation.

Compositions A and B of the invention were judged to be stable (“O”) (yes) because they did not visually exhibit phase separation, retained their color and did not form particles. The comparative compositions C-1 and C-2 were not subjected to a stability test because they failed to form emulsions that could be tested subsequently.

The preceding description illustrates and describes the invention. The disclosure presents and describes only the preferred embodiments, but it should be understood that the invention is capable of being used in various other combinations, modifications and environments and is capable of changes or modifications in the scope of the inventive concepts such as 'expressed herein, in correspondence with the above teachings and/or skill or knowledge of the related art. The embodiments described above are further intended to explain the best modes known to the applicant and to enable others skilled in the art to use the disclosure in such embodiments, or in other embodiments, and with the various modifications required by particular applications or uses thereof. Accordingly, the description is not intended to limit the invention to the form disclosed herein.

Definitions

As used herein, the term "silicone oil" means a liquid polymerized siloxane compound having an organic side chain. There are various silicone oils depending on a type of organic side chain.

As used herein, the terms “comprising”, “having” and “including” (or “understand”, “have” and “include”) are used in their open, non-limiting sense. The term “consisting essentially of” limits the scope of a claim to specified substances or steps and to those which do not materially affect the basic and novel features of the claimed invention.

The terms “un”, “une” and “le”, “la” are understood to include the plural as well as the singular.

Thus, the expression “a mixture of these” also refers to “mixtures of these”. Throughout the disclosure, if the phrase "a mixture thereof" is used, followed by a list of items as shown in the following example where the letters A-F represent the items: "one or more items selected from the group consisting of A, B, C, D, E, F, or a mixture thereof. » The phrase "a mixture of these" does not mean that the mixture includes all of A, B, C, D, E and F (even though A, B, C, D, E and F can all be included). Rather, it indicates that a mixture of any two or more of A, B, C, D, E and F may be included. In other words, it is equivalent to the expression "one or more elements chosen from the group consisting of A, B, C, D, E, F, and a mixture of any two or more of A, B, C , D, E and F”.

Likewise, the expression “a salt of these” also includes “salts of these.” » Thus, when the disclosure designates “an element chosen from the group consisting of A, B, C, D, E, F, a salt thereof or mixtures thereof,” it indicates that one or more than one of A, B, C, D and F may be included, that one or more of a salt of A, a salt of B, a salt of C, a salt of D, a salt of E and a salt of F may be included, or a mixture of any two of A, B, C, D, E, F, a salt of A, a salt of B, of a C salt, a D salt, an E salt and an F salt may be included.

Salts designated throughout the disclosure may include salts having a counterion such as an alkali metal, alkaline earth metal, or ammonium counterion. This list of counterions is, however, not exhaustive. Suitable counterions for the components described herein are known in the art.

The expression “one or more” means “at least one” and thus includes individual components as well as mixtures/combinations.

The term “plurality” means “more than one” or “two or more.”

An “alkyl radical” is a linear or branched saturated hydrocarbon group, in particular in C ₁ -C ₈ , more particularly in C ₁ -C ₆ , preferably in C ₁ -C ₄ such as methyl, ethyl, isopropyl and tert- butyl;

an “alkoxy radical” is an alkyl-oxy in which the alkyl is as described above;

an “alkenyl radical” is a linear or branched unsaturated hydrocarbon group, in particular C ₂ -C ₈ , more particularly C ₂ -C ₆ , preferably C ₂ -C ₄ such as ethylenyl, propylenyl;

an “alkylene radical” is a linear or branched divalent saturated hydrocarbon group in C ₁ -C ₈ , in particular, in C ₁ -C ₆ , preferably in C ₁ -C ₄ such as methylene, ethylene or propylene.

Some of the various categories of components identified for cosmetic compositions may have duplication. In cases where they may be duplicative and the composition/product includes two duplicative components (or more than two duplicative components), one duplicative component does not represent more than one component. For example, a certain compound may be considered both a “fatty compound” and an “emulsifier.” If a particular composition/product includes both a fatty compound and an emulsifier, the certain compound may serve only as a fatty compound or an emulsifier (a single certain compound does not serve as both a compound and an emulsifier ).

All percentages, parts and ratios are based on the total weight of the compositions of the present invention unless otherwise noted.

All ranges and values disclosed herein are inclusive and combinable. For example, any value or point described here that falls within a range described here may serve as a minimum or maximum value to infer a subrange, etc. Additionally, all ranges provided are intended to include each specific range within the given ranges, and all combinations of subranges between them. So, a range of 1 to 5, specifically includes 1, 2, 3, 4 and 5, as well as subranges such as 2 to 5, 3 to 5, 2 to 3, 2 to 4, 1 to 4 , etc. ; and 1, 2, 3, 4, and 5 include ranges and subranges 1 to 5, 2 to 5, 3 to 5, 2 to 3, 2 to 4, 1 to 4, etc.

Except in the operating examples, or unless otherwise stated, all numbers expressing quantities of ingredients and/or reaction conditions may be modified in all cases by the term "approximately", whether expressly mentioned. or not.

Furthermore, all numbers are intended to represent exact values as additional embodiments, whether or not modified by the term "approximately". For example, “an amount of approximately 1%” can be modified to mean exactly 1%. As another example, “an amount of 1%” can be modified to mean “approximately 1%.” Unless otherwise stated, the term “approximately” is understood to encompass a range of +/- 10% of the number mentioned. However, in some embodiments, the term may be defined to encompass narrower ranges, for example, +/- 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9% and 10% from the designated number.

The terms “surfactants” and “emulsifiers” include salts of surfactants and emulsifiers, although this is not explicitly stated. In other words, whenever the disclosure relates to a surfactant or emulsifier, it is understood that salts are also encompassed to the extent that such salts exist, even though the specification may not specifically refer to a salt. (or may not refer to a salt in each example throughout the disclosure), for example, by using a phrase such as "a salt thereof" or "salts thereof." Sodium and potassium are common cations that form salts with surfactants and emulsifiers. However, other cations such as ammonium ions or alkanolammonium ions, such as monoethanolammonium or triethanolammonium ions, can also form surfactant salts.

The term "substantially free" or "substantially free" as used herein means that the specific substance may be present in small quantities that do not materially affect the basic and novel characteristics of the substance. claimed invention. For example, less than 2% by weight of a specific substance may be added to a composition, based on the total weight of the compositions (provided that less than 2% by weight does not materially affect the characteristics of the composition). basis and new features of the claimed invention). Likewise, a composition "substantially free" or "essentially free" of a mentioned substance may include less than 1.5% by weight, less than 1% by weight, less than 0.5% by weight, less than 0, 1% by weight, less than 0.05% by weight or less than 0.01% by weight, or none of the specified substances. The term "substantially free" or "substantially free" as used herein may also mean that the specific substance is not added to the composition but may remain present in a raw material that is included in the composition. the composition.

Furthermore, any components which are positively stated in the present disclosure may be negatively excluded from the claims, for example, a claimed composition may be "free", "essentially free" (or "substantially free") of one or more components that are positively stated in this disclosure. For example, the cosmetic composition of the present disclosure may optionally include one or more active phenolic or polyphenolic compounds, for example, baicalin. However, in one embodiment, the cosmetic compositions may be free or substantially free of active phenolic or polyphenolic compounds, in particular baicalin.

All publications and patent applications cited in this specification are incorporated herein by reference, and for all purposes, as if specifically and individually stated that each individual publication or patent application was incorporated by reference. reference. In the event of any inconsistency between this disclosure and any publication or patent application incorporated herein by reference, this disclosure shall prevail.

Claims (10)

Cosmetic composition comprising:

1. about 10 to about 50 weight percent hydropropyl tetrahydropyrantriol;
2. about 5 to about 50% by weight of one or more silicone oils;
3. about 0.1 to about 10% by weight of one or more non-emulsifying silicone elastomers;
4. about 0.1 to about 10% by weight of one or more dimethicone copolyol emulsifiers comprising at least one oxyethylene group and at least one oxypropylene group;
5. some water ; And
6. about 0.1 to about 40% by weight of one or more water-soluble solvents;
7. wherein the composition is in the form of a water-in-silicone emulsion and all weight percentages are based on the total weight of the composition.

Cosmetic composition according to claim 1, in which the one or more silicone oils of (b) are chosen from dimethicone, dimethiconol, cyclopentasiloxane, cyclomethicone, cyclotetrasiloxane, cyclohexasiloxane, cycloheptasiloxane, decamethylcyclopentasiloxane, cyclotetrasiloxane, cyclotrisiloxane, capryldimethicone, caprylyltrimethicone, caprylylmethicone , cetearylmethicone , hexadecylmethicone, hexylmethicone, laurylmethicone, myristylmethicone, phenylmethicone, stearylmethicone, stearyldimethicone, behenyldimethicone, trifluoropropylmethicone, cetyldimethicone, polyphenylmethylsiloxane, dimethylpolysiloxane, methylphenylpolysiloxane, methyltrimethicone, diphenylsiloxyphen yl trimethicone and phenyl trimethicone, and mixtures thereof. Composition according to any one of the above claims, wherein the one or more silicone elastomers of (c) are selected from dimethicone block polymer, vinyldimethicone block polymer, dimethicone/vinyldimethicone block polymer, dimethicone block polymer- 3, polysilicone-11 and mixtures thereof. Composition according to any one of the above claims, wherein at least one of the one or more dimethicone copolyol emulsifiers comprising at least one oxyethylene group and at least one oxypropylene group (d) is selected from a dimethicone copolyol emulsifier of C ₈ -C ₂₂ alkyl comprising at least one oxyethylene group and at least one oxypropylene group. Composition according to any of the above claims comprising about 0.1 to about 70% by weight of water (e). Composition according to any one of the above claims, in which the one or more water-soluble solvents of (f) are chosen from glycerin, monoalcohols, polyols (polyhydric alcohols), glycols and a mixture thereof. Composition according to any one of the above claims, further comprising:

1. (g) one or more miscellaneous ingredients comprising one or more other miscellaneous ingredients selected from miscellaneous emulsifiers/surfactants other than (d) dimethicone copolyol emulsifiers, preservatives, fragrances, acidity regulators, salts, buffers, antioxidants, flavonoids , vitamins, botanical extracts, UV filtration agents, proteins, protein hydrolysates and/or isolates, hydrotropes, pearling agents, fillers, dyes, mattifying agents, other skin active agents, depigmentation agents, anti-wrinkle agents and mixtures of these.

Composition according to any one of the above claims, wherein the composition does not visually exhibit phase separation or form particles during at least 2 weeks of storage at 4 ^o C, 25 ^o C, 37 ^o C and /or 45 ^o C; and/or the composition does not visually exhibit phase separation or form particles during at least 10 freeze-thaw test cycles, wherein the freeze-thaw test comprises placing the cosmetic composition in a stability chamber and subjecting it to a temperature fluctuation at intervals of 12 hours, for a first interval of 12 hours at - 20 ^o C then for a second interval of 12 hours at 25 ^o C. A kit comprising the cosmetic composition according to any one of the above claims and one or more complementary skin treatment compositions, wherein the cosmetic composition and each of the one or more skin treatment compositions are contained separately. Method of treating the skin comprising applying the cosmetic composition according to any one of claims 1 to 8 to the skin.