FR3118579A1 - COMPOSITION FOR CARE OF KERATINOUS MATERIALS - Google Patents

Abstract

Composition for taking care of keratinous materials The invention relates to a composition for caring for keratinous materials, comprising, essentially consisting of, or consisting of: A) at least two bifunctional antioxidants chosen from compounds containing acid hydroxyl, also serving at least as bleaching agents, and B) at least two polyols that are liquid at room temperature, wherein at least one of the polyols is a C2-C6 polyol having 2 or 3 hydroxyl groups, wherein the composition is anhydrous. Figure for the abstract: none

Description

COMPOSITION FOR CARE OF KERATINOUS MATERIALS

The present invention relates to a cosmetic composition for caring for keratinous materials, and in particular the skin. The present invention further relates to the use of this composition, and in particular in the form of a skin care product.

Background

The cosmetic field has always had the ultimate objective of offering products with benefits for the skin such as hydration, anti-aging effect, whitening, cleansing, feeling of softness, etc.

As we age, the outer layer of skin (epidermis) becomes thinner, although the number of cell layers remains unchanged. However, the number of cells containing pigment (melanocytes) decreases. Consequently, the skin appears pale and translucent. Large pigmented spots (age spots, brown spots, or lentigines) may appear in areas exposed to the sun. Changes in connective tissue reduce the firmness and elasticity of the skin. This is known as elastosis. This is more noticeable in areas exposed to the sun (solar elastosis). Elastosis produces the weathered, weathered appearance unique to farmers, sailors and others who spend a lot of time outdoors. Dehydration increases the risk of skin damage. Poor nutrition can also have a negative impact on the skin, causing dryness, rashes and puffiness.

On the other hand, the formation of free radicals is a widely accepted essential mechanism leading to skin aging. Free radicals are highly reactive molecules with unpaired electrons that can directly damage various cell membranes, lipids, proteins, RNA and DNA. The damaging effects of these reactive oxygen species are induced internally during normal metabolism and externally through various oxidative stresses. UV exposure and environmental pollution can accelerate skin aging by producing free radicals in the skin. Antioxidants protect cells from damage caused by oxidative stress by scavenging free radicals and inhibiting subsequent oxidation reactions. Topical application of antioxidants is widely used in skin care products to prevent skin aging.

The present disclosure relates to compositions and methods of using the compositions to provide benefits to the skin. The compositions improve the appearance of the skin and provide multiple anti-aging and other benefits to the skin. The compositions are unique in their ability to provide strong antioxidant efficacy with a smooth feel.

The inventors have surprisingly discovered an anhydrous composition comprising components A) at least two bifunctional antioxidants chosen from compounds containing the acid hydroxyl, also serving at least as bleaching agents; and B) at least two polyols which are liquid at room temperature, wherein at least one of the polyols is a C2-C6 polyol having 2 or 3 hydroxyl groups.

According to one embodiment of the invention, component A), namely, bi-functional antioxidants, is used in an amount of 0.1 to 40% by weight relative to the total weight of the composition.

The composition according to the invention has in particular a fluid and light texture, suitable for use in an ampoule. The composition according to the invention is particularly stable over time, in particular against UV radiation.

The subject of the invention is also a process for caring for or making up keratinous materials, in particular the skin, for example the face, comprising the topical application to the keratinous materials of the composition according to the present invention.

The invention also relates to the use of the composition according to the present invention for taking care of or making up keratinous materials, in particular for taking care of the skin. The composition according to the present invention has in particular an improved anti-singlet oxygen effect. Accordingly, the composition according to the present invention, particularly when used in an ampoule product, is superior on radiant luminous skin and/or smooth nourished skin.

Embodiments of the Invention

Throughout the description, including in the claims, the term "comprising a" must be understood as being synonymous with "comprising at least one", unless otherwise stated. In addition, the expression "at least one" used in the present description is equivalent to the expression "one or more".

Throughout the description, including in the claims, an embodiment defined with "comprising" or the like should be understood to encompass a preferable embodiment defined with "consisting essentially of" and a preferable embodiment defined with " made of ".

Preferably, the "keratinous material" according to the present invention is the skin. By "skin" we mean all of the skin of the body. More preferably, the keratinous material is the face, or the neck, in particular the face.

By “topical application”, it is meant that the composition is applied or spread over the surface of the keratinous materials, for example, at least one zone of the skin.

In the application, unless specifically stated otherwise, the contents, parts and percentages are expressed on a weight basis.

Other than in the functional examples, or unless otherwise indicated, all numbers expressing quantities of components and/or reaction conditions shall be understood to be modified in all cases by the term "about", with a meaning generally known in art, for example, to within 10% of the indicated number (eg "about 10%" means 9% - 11% and about 2%" means 1.8% - 2.2%).

In the application, a numerical range is defined with a lower limit and an upper limit if necessary, such that one or more lower limits and one or more upper limits are given to form a range optionally in conjunction with one or more ranges favourites. A given range can be defined by selecting a lower limit and an upper limit which define the borders of the given range. All ranges defined in this manner are inclusive and combinable, i.e. any lower limit may be combined with any upper limit to form a range, provided both lower and upper limits are provided to modify the same subject. For example, where ranges of 60-110 and 80-120 are stated for a specific subject, it should be understood that ranges of 60-120 and 80-110 are also contemplated and encompassed. Further, if the lower limits indicated are 1 and 2 and the upper limits are indicated as 3, 4 and 5, the following ranges are all foreseeable and fall within the scope of this disclosure: 1-3, 1- 4, 1-5, 2-3, 2-4 and 2-5.

For the purposes of the present invention, the term "anhydrous" means the absence of water, or the presence of water in an amount which one skilled in the art can determine to be free or substantially free of water. For example, an “anhydrous” composition according to the present invention can comprise less than 2%, preferably less than 0.5% by weight of water relative to the total weight of the composition. Where appropriate, such small amounts of water may be provided by ingredients in the composition which include it in a residual amount, but are not deliberately provided.

The present invention relates to a composition for taking care of keratinous materials, comprising, essentially consisting of, or consisting of the following components:

A) at least two bifunctional antioxidants selected from hydroxy acid-containing compounds, also serving as at least bleaching agents; And

B) at least two polyols which are liquid at room temperature, wherein at least one of the polyols is a C2-C6 polyol having 2 or 3 hydroxyl groups,

wherein the composition is anhydrous.

Component A), Bifunctional antioxidants

The composition according to the present invention comprises component A), at least two bifunctional antioxidants selected from compounds containing hydroxy acid, which also serves at least as a bleaching agent for the purposes of the present invention.

Generally, a free hydroxyl group is relatively easily oxidized. Thus an antioxidant containing at least one hydroxyl group is of great interest.

The bifunctional antioxidant may be anthocyanin containing a hydroxyl group. Anthocyanins and their derivatives are antioxidants. Anthrocyanins include a class of flavonoid compounds responsible for the red, purple, and blue colors of many fruits, vegetables, seeds, and flowers, which are naturally occurring water-soluble compounds. Furthermore, anthocyanins are collagenase inhibitors. Collagenase inhibition helps prevent and reduce wrinkles caused by reduced skin collagen, increase skin elasticity, and the like. Anthocyanins can be obtained from any part of a variety of plant sources, such as fruits, flowers, stems, leaves, roots, barks or seeds. Those skilled in the art will appreciate that certain parts of the plant may comprise naturally higher levels of anthocyanins, and thus these fractions are used to obtain the desired anthocyanins. In some cases, the antioxidant may include one or more betaines. Betatine, like anthocyanins, is available from natural sources and is an antioxidant.

The bifunctional antioxidant may be a phenylpropanoid containing a hydroxyl group (a derivative of cinnamic acid). Phenylpropanoids include: caffeic acid, ferulic acid, trans-ferulic acid (including its antioxidant pharmacophore 2,6-dihydroxy acetophenome), 5-hydroxyferic acid, sinapic acid. Without limiting the mode of action of the present invention, phenylpropanoids can neutralize free radicals.

The bifunctional antioxidant may be tannin. Useful tannins include: tannins, terflavin B, glucogallin, gallic acid and quercitannic acid.

The bifunctional antioxidant can be organic acids containing a hydroxyl group, such as gallic acid, ellagic acid, cichoric acid, chlorogenic acid, rosmarinic acid, protocatechuic acid or α- hydroxy, such as lactic acid and glycolic acid and derivatives thereof as well as the acids listed in the phenylpropanoid category above.

The bifunctional antioxidant can be vitamin C or derivatives thereof containing a hydroxyl group, including ascorbic acid, sodium ascorbate, ascorbyl glycoside, glucosamine ascorbate, acetate of ascorbyl and the like. Furthermore, it is possible to use plants derived from a large amount of vitamin C, such as extracts of myrciaria dubia, acerola, emblica officinalis, and bioflavonoids from rose hips and citrus fruits, including water-soluble biflavonoids, for example, hesperidin methyl chalcone.

Other examples of bifunctional antioxidant may include hydroxytyrosolrutin, sesame phenol, polyunsaturated fatty acids, and sulfur-based antioxidants containing a hydroxyl group.

Without being bound by any known theory, it is believed that the concurrent use of at least two of the above bifunctional antioxidants may be particularly beneficial. According to one embodiment, one of the at least two bifunctional antioxidants used in parallel can be a vitamin or a derivative thereof, such as vitamin C or derivatives thereof. For example, vitamin C or vitamin E can preferably be used, for example vitamin C. According to one embodiment, the vitamin or a derivative thereof, if any, can be present in an amount of 1 to 30% by weight, preferably from 5 to 25% by weight or from 7 to 18% by weight, relative to the total weight of the composition.

According to another embodiment for the at least two bifunctional antioxidants used in parallel, one of the at least two bifunctional antioxidants can be an organic acid containing hydroxyl such as: caffeic acid, ferulic acid, trans-ferulic acid, sinapic acid, gallic acid, ellagic acid, cichoric acid, chlorogenic acid, rosmarinic acid, protocatechuic acid, lactic acid and/or glycolic acid. For example, it is preferable to use a ferulic acid, a trans-ferulic acid and/or an ellagic acid, for example, a ferulic acid. According to one embodiment, the hydroxyl-containing organic acid, if present, may be present in an amount of 0.01 to 20% by weight, preferably, 0.1 to 15% by weight or 0.5 to 3% by weight, relative to the total weight of the composition.

Component A) may be present in an amount of 0.01 to 40% by weight, preferably 0.1 to 35% by weight, 1 to 30% by weight or 5 to 20% by weight, relative to the total weight of the composition.

Component B), Polyol

The composition according to the present invention comprises a polyol, which is liquid at room temperature (25 ℃), preferably chosen in particular from polyols having in particular from 2 to 20 carbon atoms, preferably having from 2 to 10 carbon atoms and preferably having from 2 to 6 carbon atoms, such as glycerin, propylene glycol, butylene glycol, pentylene glycol, hexylene glycol, dipropylene glycol and diethylene glycol.

Preferably, the composition according to the present invention may comprise at least two polyols in parallel. According to one embodiment of the invention, of the at least two polyols used in parallel, at least one of the polyols is a C2-C6 polyol having 2 or 3 hydroxyl groups.

According to one embodiment of the invention, of the at least two polyols used in parallel, at least two, preferably all of the polyols are weak alcohols, each preferably having from 2 to 6 carbon atoms.

According to one embodiment of the invention, of the at least two polyols used in parallel, at least two polyols each comprise 2 or 3 hydroxyl groups, each preferably having from 2 to 6 carbon atoms.

According to another exemplary embodiment of the invention, of the at least two polyols used in parallel, at least two, preferably all of the polyols are each derivatives of the same alkane. For example, a combination of ethylene glycol and diethylene glycol, which are considered derivatives of ethane, can be used. As another example, a combination of two, three or four of propylene glycol, dipropylene glycol, glycerin and diglycerin which are considered derivatives of propane, can be used.

As mentioned above, component A) involves at least two bifunctional antioxidants selected from an acidic hydroxyl-containing compound, which include a hydroxyl group, as well as optionally a carboxyl group. Accordingly, for favorable dissolution and/or stability, the at least two polyols used in parallel are specifically selected as corresponding to component A), specifically corresponding to the hydroxyl arrangement thereof. For example, a polyol of the at least two polyols used in parallel can have two adjacent hydroxyl groups, such as ethylene glycol, 1,2-propylene glycol or glycerin; while the other polyol of the at least two polyols used in parallel can have non-adjacent hydroxyl groups, for example, 1,3-propylene glycol, or even hydroxyl groups as far apart as possible, for example, dipropylene glycol.

Examples of two or more polyols used in parallel can consist of a combination of dipropylene glycol and glycerine; a combination of propylene glycol, dipropylene glycol and glycerin; and a combination of propylene glycol, dipropylene glycol, glycerin and diglycerin.

According to one embodiment of the invention, of the at least two polyols used in parallel in component B), the at least two polyols can be used in similar amounts. For example, for component B), the at least two polyols used in parallel can each represent 20-55% by weight, preferably 30-50% by weight or 40-50% by weight, relative to the total weight of the component B).

Component B) may be present in an amount of 60-99.99% by weight, preferably 65-99.9% by weight, 70-99% by weight, or 80-95% by weight, with respect to the total weight of the composition.

Anhydrous form

For the purposes of the present invention, the composition according to the present invention is essentially in an anhydrous form. According to the present invention, the inclusion of water or humidity in the composition is avoided; however, those skilled in the art will readily appreciate that water cannot be 100% removed. For example, although water is not intentionally added, it may be supplied by composition ingredients which contain it in a residual amount, may be incorporated during production, or may be absorbed from the ambient atmosphere during processing. production and/or storage.

Accordingly, for the purposes of the present invention, the term "anhydrous" means the absence of water, or the presence of water in an amount which one skilled in the art can determine to be free or substantially free of water. For example, an “anhydrous” composition according to the present invention can comprise less than 2%, preferably less than 0.5% by weight of water relative to the total weight of the composition. Preferably, an "anhydrous" composition according to the present invention does not comprise a detectable amount of water, wherein the "detectable amount" means an amount which can be detected by a device ordinarily used in the art for measuring the water content.

Optionally, components A) and B), as well as, where appropriate, any other components, are subjected to a water removal step before being incorporated into the composition of the present invention. The technical means of removing water are not particularly limited, provided that the composition obtained is "anhydrous".

Additional Antioxidants

In addition to the bifunctional antioxidant used for component A), the composition according to the present invention may optionally comprise an additional antioxidant other than those specified for component A) according to the present invention.

Additional antioxidants used may include natural exogenous antioxidant phytochemicals such as phenols and carotenoids.

Additional antioxidant may include flavonoids. Flavonoids are a broad class of over 5,000 polyphenol phytochemicals with antioxidant properties that work by scavenging direct free radicals. Flavonoids have anti-inflammatory, antibacterial, antiviral, anti-allergic, anti-mutagenic, anti-thrombotic, anti-tumor and vasodilator effects and these methods of action can also be used to prevent, relieve or eliminate oxidative damage of dental instruments. Flavonoids can exhibit chelating properties with metal ions and can attenuate oxidative damage to metal ions by chelating ions. The formation and stability of the flavonoid-metal chelate depends on the function of the structure. Flavonoids having a catechol moiety and having a hydrogen bond between the 5-position and 3-position hydroxyl groups have chelating properties.

Sesamum indicum or lignan can also be added. Sesame and its lignans (fibrous compounds associated with sesame) act as antioxidants. Sesame seed lignan significantly enhances vitamin E activity.

The flavonoid may be a flavanone (a derivative of 2,3-dihydro-2-phenylbenzopyran-4-one). Flavanones include: scutellarin, eriodictin, hesperetin, hesperidin, sylvester, isosakuranetin, naringenin, naringin, pinocin, tangrine (poncirin), sakuranetin, sakura glycosides and 7-O-methyl ergophenol (Sterubin).

The flavonoid may be a dihydroflavonol (a derivative of 3-hydroxy-2,3-dihydro-2-phenylbenzopyran-4-one). Flavanols include: taxifolin, aromadrin, chrysandroside A, chrysandroside B, xeractinol, astilbine and flavonol.

The flavonoid may be a flavonoid (a derivative of 2-phenylbenzopyran-4-one). Flavonoids include: Apigenin, Luteolin, Tangeritin, Chrysin, Baicalein, Wild Baicalein, Wogonin, Synthetic Flavonoids: Diosmin and Flavonoid Esters.

The flavonoid may be a flavonol (a derivative of 3-hydroxy-2-phenylbenzopyran-4-one). Flavonols include: 3-hydroxyflavone, rhodoxanthin, quercetin, galangin, cotton dermatan, kaempferol, kaempferol, isorhamnetin, mulberry pigment, myricetin, naringin (Natsudaidain), musk flavonol (Pachypodol), quercetin, methyl rhammosin, rhamnetin, azalein , hyperoside, isoquercetin, kaempferol, myricetin, suede glycosides, robinin, rutin, spirea, xanthorhamnine, amurensin, icariin and tracuridine.

The flavonoid may be flavan-3-ol (a derivative of 2-phenyl-3,4-dihydro-2H-benzopyran-3-ol). Flavan-3-ol includes: catechin, epicatechin, epigallocatechin, epicatechin gallate, epigallocatechin gallate, epiafzelechin, fisetinidol, guibourtinidol, mesquitol and robinetinidol.

The flavonoid may be a flavan-4-ol (a derivative of 2-phenylchroman-4-ol). Flavan-4-ols include: apiforol and luteoforol.

The flavonoid may be an isoflavone (a derivative of 3-phenylbenzopyran-4-one). Isoflavones include: genistein, daidzein, garbanin A, formononetin, and equol metabolites of daidzein.

The additional antioxidant may be an anthocyanin (a cation derivative of 2-phenylbenzopyranoside). Anthocyanins include: aurantinidin, cyanidin, delphinidin, europinidin, luteolinidin, pelargonidin, malvidin, peonyidin (Peonidin)), morning glory pigment (Petunidin), pink pigment (Rosinidin) and xanthone.

The additional antioxidant may be dihydrochalcone (a derivative of 1,3-diphenyl-1-propanone). Dihydrochalcone includes: phloretin, dihydrochalcone phloridin cisplatin, aspalathin, naringin dihydrochalcone, neohesperidin dihydrochalcone and nothofagin. The mode of action of the present invention is not limited, but dihydrochalcone can exert antioxidant effect by reducing free radicals such as active oxygen and reactive nitrogen species.

The additional antioxidant may be chalcone (a derivative of 1,3-diphenyl-2-propen-1-one). Chalcone includes: zirconium, okanine, safflower, marein, sophoradine, xanthohumol, flavokvain A, flavokavain B, flavokavain C and synthetic saflacone.

The additional antioxidant may be a curcuminoid. Curcuminoids include: curcumin, demethoxycurcumin, bis-demethoxycurcumin, tetrahydrocurcumin, and tetrahydrocurcumin. Curcumin and tetrahydrocurcumin can be derived from the rhizome of turmeric. Tetrahydrocurcumin, a metabolite of curcumin, has been shown to be a stronger and more stable antioxidant than curcumin.

The additional antioxidant may be a stilbenoid. Stilbenoids include: resveratrol, red sandalwood and paclitaxel. Resveratrol may include, but is not limited to: 3,5,4'-trihydroxyindole, 3,4,3',5'-tetrahydroxyindole (ketotriol), 2,3',4,5'-tetrahydroxyindole (ketotriol), resveratrol), 4,4'-dihydroxyindole and its derivatives alpha and beta glucoside, galactoside and mannoside.

The additional antioxidant may be coumarin (a derivative of 2H-benzopyran-2-one). Coumarins include: 4-hydroxycoumarin, umbelliferone, aesculetin, herniarin, aurapten and dicoumarin.

The additional antioxidant may be a carotenoid. Carotenoids include: beta-carotene, alpha-carotene, gamma-carotene, beta-cryptoxanthin, lycopene, lutein and idebenone.

Additional antioxidant may be: xanthone, butylated hydroxytoluene, 2,6-di-tert-butylphenol, 2,4-dimethyl-6-tert-butylphenol, eugenol, acetylcysteine, S-allylcysteine, pyridone (Barbigerone), chebulagic acid, edaravone, ethoxyquin, idebenone, melatonin, n-acetyl serotonin, nordihydroguaiaretic acid, oleotanthale, oleeuropein, paradol, paclitaxel, probucol, propyl gallate, pyrithione, flax lignan diglucoside, sesamin, silybin, silymarin, theaflavins, theaflavin digallate, thymoquinone , trolox, tyrosol.

Sesamum indicum or sesame lignan can also be used. Sesame or its lignans (fibrous compounds associated with sesame) act as antioxidants. Sesame seed lignan significantly enhances vitamin E activity.

Furthermore, carotenoids, particularly of the lutein type, are also useful antioxidants which can be used. Lutein-like carotenoids include molecules such as lutein, canthaxanthin, cryptoxanthin, zeaxanthin, and astaxanthin. Lutenia compounds protect compounds such as vitamin A, vitamin E and other carotenoids.

The additional antioxidant described above can also be present according to the invention in an amount of 0.001 to 10% by weight, preferably 0.1 to 7% by weight, or preferably 0.5 to 5 % by weight, relative to the total weight of the composition of the present invention.

Conservative

For the use of the present invention, the composition according to the present invention may optionally comprise a preservative. The preservative useful according to the present invention can be any preservative traditionally used for cosmetics, in particular for products in ampoules.

For example, preservatives which can be used according to the present invention include methylchloroisothiazolinone, imidazolidinyl urea, hydantoin derivatives, such as DMDMH, parahydroxybenzoate ester, phenoxyethanol, benzyl alcohol, chlorphenesin, benzoic acid and a salt thereof, such as sodium benzoate, potassium sorbate, hydroxyacetophenone, amino acid preservative, sorbitan octanate, glycerol caprylate and similar.

The preservative may be present according to the invention in an amount of 0.01 to 5%, preferably 0.01% to 3%, preferably 0.01% to 1%, relative to the total weight of the composition of the present invention.

Gelling agent

As gelling agents, mention may be made of carboxyvinyl polymers such as Carbopols® (Carbomers) and pemulene such as Pemulen TR1® and Pemulen TR2® (acrylate/alkylacrylate C10-C30 copolymer); polyacrylamides, for example cross-linked copolymers sold under the names Sepigel 305® (CTFA name: polyacrylamide/C13-14 isoparaffin/Laureth 7) or Simulgel 600 (CTFA name: acrylamide/sodium acryloyldimethyltaurate/isohexadecane/polysorbate 80 copolymer) by the company Seppic; polymers and copolymers of 2-acrylamido-2-methylpropanesulphonic acid, optionally crosslinked and/or neutralized, such as the polyacid 2-acrylamido-2-methylpropanesulphonic marketed by Hoechst under the trademark "Hostacerin AMPS®" (CTFA name: ammonium polyacryloyldimethyl taurate or SIMULGEL 800® marketed by the company SEPPIC (CTFA name: sodium polyacryolyldimethyl taurate/polysorbate 80/sorbitan oleate); copolymers of 2-acrylamido-2-methylpropanesulphonic acid and hydroxyethyl acrylate such as SIMULGEL NS® and SEPINOV EMT 10® marketed by the company SEPPIC, cellulose derivatives such as hydroxyethylcellulose, polysaccharides and in particular gums such as xanthan gum, guar gum or carob, water-soluble or water-dispersible derivatives such as acrylic silicones, silicones of polyether and cationic silicones and mixtures thereof.

In a particularly preferred embodiment, the composition according to the invention comprises at least one polymer and one copolymer of optionally crosslinked and/or neutralized 2-acrylamido-2-methylpropanesulfonic acid, such as polyacrylic acid, 2 -acrylamido-2-methylpropanesulfonic and at least one carbovinyl polymer such as carbomers. Preferably, the composition according to the invention comprises the polyacid 2-acrylamido-2-methylpropanesulphonic marketed by the company Hoechst under the trademark "Hostacerin AMPS®" (CTFA name: ammonium polyacryloyldimethyltaurate) and at least one carboxyvinyl polymer such as Carbopols ® (Carbomers).

The gelling agents may be present in the composition according to the invention, in particular in an amount of 0.1% to 3% by weight, or in particular, from 0.5% to 2% by weight relative to the total weight of the composition.

adjuvant

In a known way, the dose forms intended for topical application can also comprise adjuvants which are usual in the cosmetic, pharmaceutical and/or dermatological field, such as gelling agents, hydrophilic or lipophilic active agents, perfumes, fillers, filters, pH regulators, odor absorbers and colorants. The amounts of these various adjuvants are those ordinarily used in the field under consideration, and for example, from 0.01 to 20% of the total weight of the composition. These adjuvants, depending on their nature, can be introduced into the aqueous phase.

These adjuvants and their concentrations may be such that they do not modify the desired property of the composition of the invention.

Additional active ingredient

The composition according to the invention can advantageously comprise one or more additional active ingredients, in particular cosmetic, dermatological or pharmaceutical.

In the context of the present invention, an additional active ingredient is an active ingredient other than component A) present in the composition and other active agents particularly defined above.

Advantageously, such an additional active ingredient, cosmetic, dermatological or pharmaceutical, can be supposed to exert a cosmetic, care or hygiene effect on keratinous materials such as the skin, including the face, the hair, the eyelashes and / or the scalp, and preferably the skin.

The choice of this additional active ingredient is obviously conditioned by the effect jointly sought by the composition in question.

Thus, a composition according to the invention may additionally comprise an active ingredient having an anti-aging activity or a moisturizing activity.

Of course, those skilled in the art will take care to choose the optional additional active ingredient(s) added to the composition according to the invention in such a way that the advantageous properties intrinsically linked to the composition according to the invention are not, or substantially not, altered by the proposed addition.

These additional active ingredients are generally present in the composition in a content of 0.0001% to 20% by weight and preferably from 0.01% to 10% by weight relative to the total weight of said composition.

The compositions according to the invention can be manufactured by known methods, generally used in the cosmetic or dermatological field.

The composition according to the invention finds its application in a large number of treatments for keratinous materials such as the skin, the scalp or the mucous membranes (lips), and more particularly the skin, in particular for the care of the skin, for nourish the skin, prevent transepidermal water loss and/or protect the skin.

The subject of the invention is also a process for caring for or making up keratinous materials, comprising the application to the keratinous materials of a composition as defined above.

The object of the present invention is in particular a method for treating dry and/or rough skin, comprising the application to the skin of a composition as defined above.

The object of the invention is in particular a method for treating mature skin, comprising the application to the skin of a composition as defined above.

The invention also relates to the use of a composition as defined above, for caring for or making up keratinous materials.

In a particular embodiment, the composition is suitable for the treatment of dry skin.

In one embodiment, the composition is suitable for treating mature skin.

Examples

The following examples of compositions according to the invention are given by way of illustration and without limitation. Compounds are indicated by a chemical name or INCI name.

The quantities/concentrations of ingredients in the compositions/formulas indicated below are expressed in % by weight, relative to the total weight of each composition/formula, unless otherwise indicated.

[Table 1]

Compositions of Inventive Example 1 and Comparative Examples 1-2; Chemical name or INCI Content
(% in weight) Ex.1 Example comp.1 GLYCERIN 42.5% / DIPROPYLENE GLYCOL 42.5% 42.5% PROPYLENE GLYCOL / 42.5% POLYGONUM CUSPIDATUM ROOT EXTRACT
(available from GUILIN LAYN NATURAL INGREDIENTS) 0.5% 0.5% ASCORBIC ACID 12.6% 12.6% FERULIC ACID 1.9% 1.9%

The procedures for preparing the compositions in the examples above have been briefly presented as follows:

1). weigh all the ingredients and mix them;

2). stir the ingredients at a temperature of 80℃ until dissolved; And

3). cool to room temperature.

Assessment

Evaluation of the stability of the compositions.

The procedures for evaluating the stability of each composition have been briefly presented as follows:

1) Pack the compositions of Example 1 and Comparative Example 1 respectively into 60ml glass vials and place them respectively at room temperature, and at 4℃, 37℃ and 45℃ for 2 months to observe the state at each temperature;

2) after 2 months, take out the compositions so that they reach room temperature, and observe the appearance, color and smell of the compositions; And

3) Measure the active contents of the compositions which have been placed at 45℃.

[Table 2]

Composition performance Properties Ex.1 e.g. comp. 1 T2M stability test Ambient temperature FAILURE FAILURE ;
CRYSTALS 4℃ FAILURE FAILURE ;
CRYSTALS 37℃ FAILURE FAILURE;
CRYSTALS 45℃ FAILURE FAILURE ;
CRYSTALS Active content at temp. ambient T2M (%) ASCORBIC ACID 98.4% 80% FERULIC ACID 100% 100%

It is observed that after two months, 100% of the ferulic acid is retained both for example 1 and comparative example 1: however, with regard to ascorbic acid, up to 98, 4% of the ascorbic acid was kept for Example 1 while only 80% of the ascorbic acid was kept for Comparative Example 1.

Claims (10)

Composition for taking care of keratinous materials, comprising, essentially consisting of, or consisting of the following components:
A) at least two bifunctional antioxidants selected from compounds containing hydroxy acid, also serving as at least bleaching agents; And
B) at least two polyols which are liquid at room temperature, wherein at least one of the polyols is a C2-C6 polyol having 2 or 3 hydroxyl groups,
wherein the composition is anhydrous. Composition according to Claim 1, characterized in that one of the at least two bifunctional antioxidants used in parallel is a vitamin or a derivative thereof, such as vitamin C or derivatives thereof. Composition according to Claim 2, characterized in that the vitamin or a derivative thereof must be present in an amount of 1 to 30% by weight, preferably 5 to 25% by weight, or 7 to 18% by weight, relative to the total weight of the composition. Composition according to any one of the preceding claims, characterized in that one of the at least two bifunctional antioxidants is an organic acid containing hydroxyl, such as caffeic acid, ferulic acid, trans-ferulic acid, sinapic acid, gallic acid, ellagic acid, cichoric acid, chlorogenic acid, rosmarinic acid, protocatechuic acid, lactic and/or glycolic acid. Composition according to any one of the preceding claims, characterized in that component B) is chosen from polyols having from 2 to 20 carbon atoms, preferably having from 2 to 10 carbon atoms and preferably having from 2 to 6 carbon atoms, such as glycerine, propylene glycol, butylene glycol, hexylene glycol, dipropylene glycol and/or diethylene glycol. Composition according to any one of the preceding claims, characterized in that at least two, preferably all, of the polyols are weak alcohols, each preferably having from 2 to 6 carbon atoms. Composition according to any one of the preceding claims, characterized in that for component B), a polyol of the at least two polyols used in parallel can have at least two adjacent hydroxyl groups, such as ethylene glycol, 1,2-propylene glycol or glycerin, whereas the other polyol of the at least two polyols used in parallel can have non-adjacent hydroxyl groups, such as 1,3-propylene glycol, or even hydroxyl groups as far apart as possible, for example, dipropylene glycol . Composition according to any one of the preceding claims, characterized in that the composition comprises an additional antioxidant chosen from a natural exogenous phytochemical antioxidant, a flavonoid, a carotenoid, a dihydrochalcone, a chalcone, a curcuminoid, a stilbenoid, a coumarin, a carotenoid or a mixture thereof. Use of the composition according to any one of the preceding claims for taking care of keratinous materials, in particular for topical application to the skin. Process for caring for or making up keratinous materials, comprising the application to the keratinous materials of the composition according to any one of Claims 1 to 8.