FR3116274B1 - Tétrapeptides, compositions les comprenant et leur utilisation cosmétique - Google Patents
Tétrapeptides, compositions les comprenant et leur utilisation cosmétique Download PDFInfo
- Publication number
- FR3116274B1 FR3116274B1 FR2011743A FR2011743A FR3116274B1 FR 3116274 B1 FR3116274 B1 FR 3116274B1 FR 2011743 A FR2011743 A FR 2011743A FR 2011743 A FR2011743 A FR 2011743A FR 3116274 B1 FR3116274 B1 FR 3116274B1
- Authority
- FR
- France
- Prior art keywords
- skin
- chosen
- tetrapeptides
- group
- compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000002537 cosmetic Substances 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 2
- 229910052717 sulfur Inorganic materials 0.000 abstract 2
- 102000008186 Collagen Human genes 0.000 abstract 1
- 108010035532 Collagen Proteins 0.000 abstract 1
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 abstract 1
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 abstract 1
- 102000016359 Fibronectins Human genes 0.000 abstract 1
- 108010067306 Fibronectins Proteins 0.000 abstract 1
- 206010040925 Skin striae Diseases 0.000 abstract 1
- 208000031439 Striae Distensae Diseases 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000002877 alkyl aryl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000003712 anti-aging effect Effects 0.000 abstract 1
- 230000001153 anti-wrinkle effect Effects 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 125000004057 biotinyl group Chemical group [H]N1C(=O)N([H])[C@]2([H])[C@@]([H])(SC([H])([H])[C@]12[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(*)=O 0.000 abstract 1
- 150000001720 carbohydrates Chemical class 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 229920001436 collagen Polymers 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 230000002500 effect on skin Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 210000002744 extracellular matrix Anatomy 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 101150009274 nhr-1 gene Proteins 0.000 abstract 1
- 125000003367 polycyclic group Chemical group 0.000 abstract 1
- 238000007665 sagging Methods 0.000 abstract 1
- 230000037067 skin hydration Effects 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4986—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with sulfur as the only hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1019—Tetrapeptides with the first amino acid being basic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1021—Tetrapeptides with the first amino acid being acidic
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Dermatology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Emergency Medicine (AREA)
- Cosmetics (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Tétrapeptides, compositions les comprenant et leur utilisation cosmétique Tétrapeptide de formule X-LKLE-Z ou X-ELED-Z, avec en extrémité N-terminale X choisi parmi H, -CO-R1, -SO2-R1 ou un groupe biotinoyle ; en extrémité C-terminale Z choisi parmi OH, OR1, NH2, NHR1 ou NR1R2 ; et R1 et R2 étant, indépendamment l’un de l’autre, choisis parmi un groupe alkyle, aryle, aralkyle, alkylaryl, alkoxy, saccharide et aryloxy, pouvant être linéaire, ramifié, cyclique, polycyclique, insaturé, hydroxylé, carbonylé, phosphorylé et/ou soufré, ledit groupe ayant de 1 à 24 atomes de carbone et pouvant posséder dans son squelette un ou plusieurs hétéroatomes O, S et/ou N.Ces tétrapeptides stimulent la synthèse des molécules constituant la matrice extracellulaire dermique, notamment le collagène 1 et 4 et la fibronectine et peuvent être utilisés pour un traitement cosmétique notamment anti-âge, anti-rides et ridules, pour améliorer les propriétés mécaniques de la peau, fermeté/tonicité/élasticité/souplesse, pour augmenter la densité et le volume de la peau, pour un effet restructurant et/ou pour lutter contre les vergétures, pour prévenir et/ou traiter une perte d’hydratation de la peau; et/ou pour lutter contre l’affaissement cutané.
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR2011743A FR3116274B1 (fr) | 2020-11-17 | 2020-11-17 | Tétrapeptides, compositions les comprenant et leur utilisation cosmétique |
PCT/EP2021/081930 WO2022106444A1 (fr) | 2020-11-17 | 2021-11-17 | Tétrapeptides, compositions les comprenant et leur utilisation cosmétique |
US18/035,840 US20230398049A1 (en) | 2020-11-17 | 2021-11-17 | Tetrapeptides, compositions comprising them, and their cosmetic use |
EP21810617.7A EP4247836A1 (fr) | 2020-11-17 | 2021-11-17 | Tétrapeptides, compositions les comprenant et leur utilisation cosmétique |
CN202180077351.0A CN116615177A (zh) | 2020-11-17 | 2021-11-17 | 四肽、包含其的组合物及其美容用途 |
KR1020237020305A KR20230110550A (ko) | 2020-11-17 | 2021-11-17 | 테트라펩타이드, 이를 포함하는 조성물, 및 이의 화장품 용도 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR2011743 | 2020-11-17 | ||
FR2011743A FR3116274B1 (fr) | 2020-11-17 | 2020-11-17 | Tétrapeptides, compositions les comprenant et leur utilisation cosmétique |
Publications (2)
Publication Number | Publication Date |
---|---|
FR3116274A1 FR3116274A1 (fr) | 2022-05-20 |
FR3116274B1 true FR3116274B1 (fr) | 2023-12-08 |
Family
ID=74347291
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR2011743A Active FR3116274B1 (fr) | 2020-11-17 | 2020-11-17 | Tétrapeptides, compositions les comprenant et leur utilisation cosmétique |
Country Status (6)
Country | Link |
---|---|
US (1) | US20230398049A1 (fr) |
EP (1) | EP4247836A1 (fr) |
KR (1) | KR20230110550A (fr) |
CN (1) | CN116615177A (fr) |
FR (1) | FR3116274B1 (fr) |
WO (1) | WO2022106444A1 (fr) |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7824680B2 (en) * | 2001-08-06 | 2010-11-02 | The Regents Of The University Of California | Methods for inhibiting angiogenesis |
WO2005033275A2 (fr) * | 2003-09-29 | 2005-04-14 | The Regents Of The University Of California | Procedes permettant de modifier l'adhesion, la differenciation et la migration de cellules progenitrices hematopoietiques |
US20100273718A1 (en) * | 2006-12-20 | 2010-10-28 | Danisco A/S | Milk Protein Hydrolyzates with Reduced Immunogenic Potential |
FR2998570B1 (fr) | 2012-11-26 | 2016-12-02 | Sederma Sa | Peptides, compositions les comprenant et utilisations notamment cosmetiques propigmentantes |
FR3021319B1 (fr) | 2014-05-22 | 2018-08-31 | Sederma | Peptides, compositions les comprenant et utilisations notamment cosmetiques |
FR3029782B1 (fr) | 2014-12-16 | 2019-06-07 | Sederma | Composes peptidiques, compositions les comprenant et utilisations notamment cosmetiques |
FR3052453B1 (fr) | 2016-06-14 | 2018-05-18 | Sederma | Peptide, composition le comprenant et utilisations notamment cosmetiques |
-
2020
- 2020-11-17 FR FR2011743A patent/FR3116274B1/fr active Active
-
2021
- 2021-11-17 EP EP21810617.7A patent/EP4247836A1/fr active Pending
- 2021-11-17 US US18/035,840 patent/US20230398049A1/en active Pending
- 2021-11-17 WO PCT/EP2021/081930 patent/WO2022106444A1/fr active Application Filing
- 2021-11-17 CN CN202180077351.0A patent/CN116615177A/zh active Pending
- 2021-11-17 KR KR1020237020305A patent/KR20230110550A/ko unknown
Also Published As
Publication number | Publication date |
---|---|
CN116615177A (zh) | 2023-08-18 |
US20230398049A1 (en) | 2023-12-14 |
KR20230110550A (ko) | 2023-07-24 |
FR3116274A1 (fr) | 2022-05-20 |
EP4247836A1 (fr) | 2023-09-27 |
WO2022106444A1 (fr) | 2022-05-27 |
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Effective date: 20220520 |
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