FR2988M - Drug for the treatment of mental illnesses and for combating pain, based on a new series of 1-phenyl-4-oxo-8- (aryl-pentenyl) -1,3,8-triazaspiro (4,5) decanes. - Google Patents
Drug for the treatment of mental illnesses and for combating pain, based on a new series of 1-phenyl-4-oxo-8- (aryl-pentenyl) -1,3,8-triazaspiro (4,5) decanes.Info
- Publication number
- FR2988M FR2988M FR948243A FR948243A FR2988M FR 2988 M FR2988 M FR 2988M FR 948243 A FR948243 A FR 948243A FR 948243 A FR948243 A FR 948243A FR 2988 M FR2988 M FR 2988M
- Authority
- FR
- France
- Prior art keywords
- decanes
- triazaspiro
- pentenyl
- oxo
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
- C07D211/66—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having a hetero atom as the second substituent in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Wire Processing (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20462362A | 1962-06-22 | 1962-06-22 | |
| FR939044 | 1963-06-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2988M true FR2988M (en) | 1964-12-07 |
Family
ID=22758700
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR1573808D Expired FR1573808A (en) | 1962-06-22 | 1963-06-22 | |
| FR948243A Active FR2988M (en) | 1962-06-22 | 1963-09-20 | Drug for the treatment of mental illnesses and for combating pain, based on a new series of 1-phenyl-4-oxo-8- (aryl-pentenyl) -1,3,8-triazaspiro (4,5) decanes. |
| FR948240A Active FR3043M (en) | 1962-06-22 | 1963-09-20 | Medicinal product based on a new series of 1-aryl-4-oxo-1,3,8-triazaspiro- (4,5) -decanes, substituted in position 8 or their salts for the treatment of mental disorders. |
| FR948241A Active FR2986M (en) | 1962-06-22 | 1963-09-20 | Medicinal product based on new 1-aryl-4-oxo-8-aralkyl-1,3,8-triazaspiro (4,5) decanes, as well as their salts with analgesic action. |
| FR948242A Active FR2987M (en) | 1962-06-22 | 1963-09-20 | Medicinal product based on a new series of 8- [2- (1,4-benzodioxannyl) -methyl] -1,3,8-triazaspiro (4,5) decanes, as well as their salts. |
| FR948244A Active FR3059M (en) | 1962-06-22 | 1963-09-20 | Medicinal product for the treatment of mental and cardiovascular disorders containing a new series of 1-phenyl-4-oxo-1,3,8-triazaspiro- [4,5] -decanes or their salts. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR1573808D Expired FR1573808A (en) | 1962-06-22 | 1963-06-22 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR948240A Active FR3043M (en) | 1962-06-22 | 1963-09-20 | Medicinal product based on a new series of 1-aryl-4-oxo-1,3,8-triazaspiro- (4,5) -decanes, substituted in position 8 or their salts for the treatment of mental disorders. |
| FR948241A Active FR2986M (en) | 1962-06-22 | 1963-09-20 | Medicinal product based on new 1-aryl-4-oxo-8-aralkyl-1,3,8-triazaspiro (4,5) decanes, as well as their salts with analgesic action. |
| FR948242A Active FR2987M (en) | 1962-06-22 | 1963-09-20 | Medicinal product based on a new series of 8- [2- (1,4-benzodioxannyl) -methyl] -1,3,8-triazaspiro (4,5) decanes, as well as their salts. |
| FR948244A Active FR3059M (en) | 1962-06-22 | 1963-09-20 | Medicinal product for the treatment of mental and cardiovascular disorders containing a new series of 1-phenyl-4-oxo-1,3,8-triazaspiro- [4,5] -decanes or their salts. |
Country Status (9)
| Country | Link |
|---|---|
| BE (1) | BE633914A (en) |
| CH (1) | CH462835A (en) |
| DE (1) | DE1470125C3 (en) |
| DK (1) | DK119880B (en) |
| FI (1) | FI46967C (en) |
| FR (6) | FR1573808A (en) |
| GB (1) | GB1043141A (en) |
| NO (1) | NO117368B (en) |
| SE (1) | SE311019B (en) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4080328A (en) * | 1971-07-13 | 1978-03-21 | Sumitomo Chemical Company, Limited | N-substituted heterocyclic derivatives and preparation thereof |
| BE792187A (en) * | 1971-12-03 | 1973-03-30 | Sumitomo Chemical Co | NEW ALKYLAMINE DERIVATIVES |
| US4066772A (en) * | 1975-07-21 | 1978-01-03 | Janssen Pharmaceutica N.V. | 1,3-Dihydro-1-[3-(1-piperidinyl)propyl]-2H-benzimidazol-2-ones and related compounds |
| NZ181256A (en) * | 1975-07-21 | 1978-04-28 | Janssen Pharmaceutica Nv | 1-(w-benzazol-11-ylalkyl)-piperidine derivatives and pharmaceutical compositions containing certain of these derivatives |
| DK139684A (en) * | 1983-04-11 | 1984-10-12 | Janssen Pharmaceutica Nv | N-aryl-alpha-amino carboxamides |
| US5244902A (en) * | 1989-08-21 | 1993-09-14 | Beth Israel Hospital Association | Topical application of spiperone or derivatives thereof for treatment of pathological conditions associated with immune responses |
| US5703088A (en) * | 1989-08-21 | 1997-12-30 | Beth Israel Deaconess Medical Center, Inc. | Topical application of spiperone or derivatives thereof for treatment of pathological conditions associated with immune responses |
| US5574041A (en) * | 1990-03-16 | 1996-11-12 | Beth Israel Hospital Association | Use of spiperone derivatives as immunosuppressant agents |
| US5693645A (en) * | 1992-12-23 | 1997-12-02 | Beth Israel Deaconess Medical Center, Inc. | Use of spiperone or spiperone derivatives as immunosuppressant agents |
| DE19610397A1 (en) * | 1996-03-16 | 1997-09-18 | Krewel Meuselbach Gmbh | Production of fluspirilene suspensions |
| AU3809999A (en) * | 1998-05-18 | 1999-12-06 | Novo Nordisk A/S | Novel 1,3,8-triazaspiro[4.5]decanones with high affinity for opioid receptor subtypes |
| US6277991B1 (en) | 1998-05-18 | 2001-08-21 | Novo Nordisk A/S | 1,3,8-triazaspiro[4.5]decanones with high affinity for opioid receptor subtypes |
| US6262066B1 (en) * | 1998-07-27 | 2001-07-17 | Schering Corporation | High affinity ligands for nociceptin receptor ORL-1 |
| DE69923744T2 (en) * | 1998-10-23 | 2006-02-23 | Pfizer Inc. | 1,3,8-triazaspiro [4,5] decanone compounds as orl1-receptor agonists |
| US7459461B2 (en) | 2001-10-19 | 2008-12-02 | Ortho-Mcneil Pharmaceutical, Inc. | Phosphonic acid compounds as inhibitors of serine proteases |
| DE102005038141A1 (en) * | 2005-08-12 | 2007-02-15 | Grünenthal GmbH | Substituted 8- (3-aminopropyl) -1-phenyl-1,3,8-triaza-spiro [4.5] decan-4-one derivatives |
| JP5860457B2 (en) * | 2010-06-18 | 2016-02-16 | アルトス・セラピューティクス・リミテッド・ライアビリティ・カンパニーＡｌｔｏｓ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｌｌｃ | D2 antagonist, method of synthesis and use thereof |
| IT201800007580A1 (en) * | 2018-07-27 | 2020-01-27 | Maria Cecilia Hospital Spa | 1,3,8-triazaspiro compounds and their use as medicaments |
-
0
- BE BE633914D patent/BE633914A/xx unknown
-
1963
- 1963-06-19 SE SE6834/63A patent/SE311019B/xx unknown
- 1963-06-21 FI FI631267A patent/FI46967C/en active
- 1963-06-21 DE DE1470125A patent/DE1470125C3/en not_active Expired
- 1963-06-21 CH CH776363A patent/CH462835A/en unknown
- 1963-06-21 NO NO149114A patent/NO117368B/no unknown
- 1963-06-21 GB GB24824/63A patent/GB1043141A/en not_active Expired
- 1963-06-22 FR FR1573808D patent/FR1573808A/fr not_active Expired
- 1963-06-22 DK DK297763AA patent/DK119880B/en unknown
- 1963-09-20 FR FR948243A patent/FR2988M/en active Active
- 1963-09-20 FR FR948240A patent/FR3043M/en active Active
- 1963-09-20 FR FR948241A patent/FR2986M/en active Active
- 1963-09-20 FR FR948242A patent/FR2987M/en active Active
- 1963-09-20 FR FR948244A patent/FR3059M/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| FR3043M (en) | 1965-01-04 |
| FR1573808A (en) | 1969-07-11 |
| FR2986M (en) | 1964-12-07 |
| SE311019B (en) | 1969-05-27 |
| FR2987M (en) | 1964-12-07 |
| CH462835A (en) | 1968-09-30 |
| FI46967B (en) | 1973-05-02 |
| NO117368B (en) | 1969-08-04 |
| DK119880B (en) | 1971-03-08 |
| GB1043141A (en) | 1966-09-21 |
| DE1470125C3 (en) | 1980-07-10 |
| FI46967C (en) | 1973-08-10 |
| FR3059M (en) | 1965-01-11 |
| BE633914A (en) | |
| DE1470125B2 (en) | 1979-10-31 |
| DE1470125A1 (en) | 1969-05-08 |
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