FI46967C - Process for the preparation of therapeutically valuable 4-oxo-1,3,8-triazaspiro (4,5) decanes and their acid addition salts - Google Patents
Process for the preparation of therapeutically valuable 4-oxo-1,3,8-triazaspiro (4,5) decanes and their acid addition saltsInfo
- Publication number
- FI46967C FI46967C FI631267A FI126763A FI46967C FI 46967 C FI46967 C FI 46967C FI 631267 A FI631267 A FI 631267A FI 126763 A FI126763 A FI 126763A FI 46967 C FI46967 C FI 46967C
- Authority
- FI
- Finland
- Prior art keywords
- decanes
- triazaspiro
- oxo
- preparation
- acid addition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
- C07D211/66—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having a hetero atom as the second substituent in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Wire Processing (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20462362A | 1962-06-22 | 1962-06-22 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI46967B FI46967B (en) | 1973-05-02 |
| FI46967C true FI46967C (en) | 1973-08-10 |
Family
ID=22758700
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI631267A FI46967C (en) | 1962-06-22 | 1963-06-21 | Process for the preparation of therapeutically valuable 4-oxo-1,3,8-triazaspiro (4,5) decanes and their acid addition salts |
Country Status (9)
| Country | Link |
|---|---|
| BE (1) | BE633914A (en) |
| CH (1) | CH462835A (en) |
| DE (1) | DE1470125C3 (en) |
| DK (1) | DK119880B (en) |
| FI (1) | FI46967C (en) |
| FR (6) | FR1573808A (en) |
| GB (1) | GB1043141A (en) |
| NO (1) | NO117368B (en) |
| SE (1) | SE311019B (en) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4080328A (en) * | 1971-07-13 | 1978-03-21 | Sumitomo Chemical Company, Limited | N-substituted heterocyclic derivatives and preparation thereof |
| BE792187A (en) * | 1971-12-03 | 1973-03-30 | Sumitomo Chemical Co | NEW ALKYLAMINE DERIVATIVES |
| US4066772A (en) * | 1975-07-21 | 1978-01-03 | Janssen Pharmaceutica N.V. | 1,3-Dihydro-1-[3-(1-piperidinyl)propyl]-2H-benzimidazol-2-ones and related compounds |
| NZ181256A (en) * | 1975-07-21 | 1978-04-28 | Janssen Pharmaceutica Nv | 1-(w-benzazol-11-ylalkyl)-piperidine derivatives and pharmaceutical compositions containing certain of these derivatives |
| DK139684A (en) * | 1983-04-11 | 1984-10-12 | Janssen Pharmaceutica Nv | N-aryl-alpha-amino carboxamides |
| US5703088A (en) * | 1989-08-21 | 1997-12-30 | Beth Israel Deaconess Medical Center, Inc. | Topical application of spiperone or derivatives thereof for treatment of pathological conditions associated with immune responses |
| US5244902A (en) * | 1989-08-21 | 1993-09-14 | Beth Israel Hospital Association | Topical application of spiperone or derivatives thereof for treatment of pathological conditions associated with immune responses |
| US5574041A (en) * | 1990-03-16 | 1996-11-12 | Beth Israel Hospital Association | Use of spiperone derivatives as immunosuppressant agents |
| US5693645A (en) * | 1992-12-23 | 1997-12-02 | Beth Israel Deaconess Medical Center, Inc. | Use of spiperone or spiperone derivatives as immunosuppressant agents |
| DE19610397A1 (en) * | 1996-03-16 | 1997-09-18 | Krewel Meuselbach Gmbh | Production of fluspirilene suspensions |
| US6277991B1 (en) | 1998-05-18 | 2001-08-21 | Novo Nordisk A/S | 1,3,8-triazaspiro[4.5]decanones with high affinity for opioid receptor subtypes |
| EP1080091A1 (en) * | 1998-05-18 | 2001-03-07 | Novo Nordisk A/S | Novel 1,3,8-triazaspiro[4.5]decanones with high affinity for opioid receptor subtypes |
| US6262066B1 (en) | 1998-07-27 | 2001-07-17 | Schering Corporation | High affinity ligands for nociceptin receptor ORL-1 |
| ES2237047T3 (en) * | 1998-10-23 | 2005-07-16 | Pfizer Inc. | 1,3,8-TRIAZAESPIRO (4,5) DECANONE COMPOUNDS AS ORL1 RECEIVER AGONISTS. |
| US7459461B2 (en) | 2001-10-19 | 2008-12-02 | Ortho-Mcneil Pharmaceutical, Inc. | Phosphonic acid compounds as inhibitors of serine proteases |
| DE102005038141A1 (en) * | 2005-08-12 | 2007-02-15 | Grünenthal GmbH | Substituted 8- (3-aminopropyl) -1-phenyl-1,3,8-triaza-spiro [4.5] decan-4-one derivatives |
| KR101601383B1 (en) * | 2010-06-18 | 2016-03-08 | 알토스 세라퓨틱스, 엘엘씨 | D2 antagonists, methods of synthesis and methods of use |
| IT201800007580A1 (en) * | 2018-07-27 | 2020-01-27 | Maria Cecilia Hospital Spa | 1,3,8-triazaspiro compounds and their use as medicaments |
-
0
- BE BE633914D patent/BE633914A/xx unknown
-
1963
- 1963-06-19 SE SE6834/63A patent/SE311019B/xx unknown
- 1963-06-21 FI FI631267A patent/FI46967C/en active
- 1963-06-21 GB GB24824/63A patent/GB1043141A/en not_active Expired
- 1963-06-21 NO NO149114A patent/NO117368B/no unknown
- 1963-06-21 DE DE1470125A patent/DE1470125C3/en not_active Expired
- 1963-06-21 CH CH776363A patent/CH462835A/en unknown
- 1963-06-22 FR FR1573808D patent/FR1573808A/fr not_active Expired
- 1963-06-22 DK DK297763AA patent/DK119880B/en unknown
- 1963-09-20 FR FR948242A patent/FR2987M/en active Active
- 1963-09-20 FR FR948244A patent/FR3059M/en active Active
- 1963-09-20 FR FR948240A patent/FR3043M/en active Active
- 1963-09-20 FR FR948241A patent/FR2986M/en active Active
- 1963-09-20 FR FR948243A patent/FR2988M/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| DE1470125B2 (en) | 1979-10-31 |
| CH462835A (en) | 1968-09-30 |
| NO117368B (en) | 1969-08-04 |
| FR3059M (en) | 1965-01-11 |
| FR2986M (en) | 1964-12-07 |
| FI46967B (en) | 1973-05-02 |
| DE1470125C3 (en) | 1980-07-10 |
| FR2988M (en) | 1964-12-07 |
| SE311019B (en) | 1969-05-27 |
| DK119880B (en) | 1971-03-08 |
| FR3043M (en) | 1965-01-04 |
| DE1470125A1 (en) | 1969-05-08 |
| FR2987M (en) | 1964-12-07 |
| GB1043141A (en) | 1966-09-21 |
| BE633914A (en) | |
| FR1573808A (en) | 1969-07-11 |
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