FR2970966B1 - Nouveaux derives de 1,5-dihydropyrrol-2-one, utiles pour le traitement du paludisme ou d'autres maladies parasitaires et fongiques - Google Patents

Nouveaux derives de 1,5-dihydropyrrol-2-one, utiles pour le traitement du paludisme ou d'autres maladies parasitaires et fongiques

Info

Publication number
FR2970966B1
FR2970966B1 FR1150784A FR1150784A FR2970966B1 FR 2970966 B1 FR2970966 B1 FR 2970966B1 FR 1150784 A FR1150784 A FR 1150784A FR 1150784 A FR1150784 A FR 1150784A FR 2970966 B1 FR2970966 B1 FR 2970966B1
Authority
FR
France
Prior art keywords
malaria
dihydropyrrol
parasitic
novel
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR1150784A
Other languages
English (en)
Other versions
FR2970966A1 (fr
Inventor
Maurice Medebielle
Jean-Philippe Bouillon
Stephane Picot
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
INST NAT SCIENCES APPLIQ
Centre National de la Recherche Scientifique CNRS
Universite Claude Bernard Lyon 1 UCBL
Universite de Rouen
Hospices Civils de Lyon HCL
Institut National des Sciences Appliquees de Lyon
Original Assignee
INST NAT SCIENCES APPLIQ
Centre National de la Recherche Scientifique CNRS
Universite Claude Bernard Lyon 1 UCBL
Universite de Rouen
Hospices Civils de Lyon HCL
Institut National des Sciences Appliquees de Lyon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by INST NAT SCIENCES APPLIQ, Centre National de la Recherche Scientifique CNRS, Universite Claude Bernard Lyon 1 UCBL, Universite de Rouen, Hospices Civils de Lyon HCL, Institut National des Sciences Appliquees de Lyon filed Critical INST NAT SCIENCES APPLIQ
Priority to FR1150784A priority Critical patent/FR2970966B1/fr
Priority to PCT/FR2012/050200 priority patent/WO2012104538A1/fr
Publication of FR2970966A1 publication Critical patent/FR2970966A1/fr
Application granted granted Critical
Publication of FR2970966B1 publication Critical patent/FR2970966B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR1150784A 2011-02-01 2011-02-01 Nouveaux derives de 1,5-dihydropyrrol-2-one, utiles pour le traitement du paludisme ou d'autres maladies parasitaires et fongiques Expired - Fee Related FR2970966B1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR1150784A FR2970966B1 (fr) 2011-02-01 2011-02-01 Nouveaux derives de 1,5-dihydropyrrol-2-one, utiles pour le traitement du paludisme ou d'autres maladies parasitaires et fongiques
PCT/FR2012/050200 WO2012104538A1 (fr) 2011-02-01 2012-01-31 Nouveaux dérivés de 1, 5 - dihydropyrrol - 2 - one utiles pour le traitement paludisme ou d'autres maladies parasitaires et fongiques

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1150784A FR2970966B1 (fr) 2011-02-01 2011-02-01 Nouveaux derives de 1,5-dihydropyrrol-2-one, utiles pour le traitement du paludisme ou d'autres maladies parasitaires et fongiques

Publications (2)

Publication Number Publication Date
FR2970966A1 FR2970966A1 (fr) 2012-08-03
FR2970966B1 true FR2970966B1 (fr) 2013-11-22

Family

ID=43797473

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1150784A Expired - Fee Related FR2970966B1 (fr) 2011-02-01 2011-02-01 Nouveaux derives de 1,5-dihydropyrrol-2-one, utiles pour le traitement du paludisme ou d'autres maladies parasitaires et fongiques

Country Status (2)

Country Link
FR (1) FR2970966B1 (fr)
WO (1) WO2012104538A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2014222637B2 (en) * 2013-02-28 2017-08-10 Syngenta Participations Ag Plant growth regulating compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003081945A (ja) 2001-09-13 2003-03-19 Shionogi & Co Ltd 有害微生物の防除活性を有する新規キノリン系化合物
EP2006287B1 (fr) 2006-02-27 2011-08-31 Nagoya City University Compose ayant une activite antimalarique et medicament antimalarique le contenant en tant que substance active

Also Published As

Publication number Publication date
FR2970966A1 (fr) 2012-08-03
WO2012104538A1 (fr) 2012-08-09

Similar Documents

Publication Publication Date Title
MX2021006421A (es) Anilidas de aminoácidos como moduladores de moléculas pequeñas de interleucinas-17 (il-17).
EA201000805A1 (ru) Бис-(сульфониламино)производные в терапии 066
EA201001013A1 (ru) Бис(сульфониламино)производные для применения в терапии
EA201490357A1 (ru) Индазолы
EA201500298A1 (ru) Алкоксипиразолы в качестве активаторов растворимой гуанилатциклазы
EA201691428A1 (ru) Бициклические гетероциклические производные в качестве ингибиторов irak4
UA108926C2 (ru) LibreOffice? [2,3-D] +" +" !+
MY180666A (en) Substituted pyrazolo [3,4-b] pyridines as medicaments
EA201391263A1 (ru) Комбинированные терапии гематологических опухолей
EA201400358A1 (ru) Замещенные n-[1-циано-2-(фенил)этил]-2-азабицикло[2.2.1]гептан-3-карбоксамидные ингибиторы катепсина с
EA201500544A1 (ru) НОВЫЕ БИЦИКЛИЧЕСКИЕ СОЕДИНЕНИЯ И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ АНТИБАКТЕРИАЛЬНЫХ АГЕНТОВ И ИНГИБИТОРОВ β-ЛАКТАМАЗ
MX2013012776A (es) Inhibidores de la tirosina cinasa de bazo que contienen aminopiridina.
EA201590453A1 (ru) Конденсированные бициклические производные сульфамоила и их применение в качестве лекарственных препаратов для лечения гепатита b
EA201590371A1 (ru) 1,4-дизамещенные аналоги пиридазина и способы лечения связанных с дефицитом smn состояний
EA201491356A1 (ru) Ингибиторы протеинкиназ (варианты), их применение для лечения онкологических заболеваний и фармацевтическая композиция на их основе
ATE440834T1 (de) Substituierte arylaminderivate und verwendungsverfahren
MY161233A (en) Bis (fluoroalkyl)-1, 4-benzodiazepinone compounds
EA201390723A1 (ru) Аминозамещенные производные бисфенилпентановой кислоты в качестве ингибиторов nep
EA201391486A1 (ru) Способы и композиции для лечения болезни паркинсона
EA201300250A1 (ru) Оксадиазольные ингибиторы продуцирования лейкотриена
EA201490471A1 (ru) Пиридазиноновые соединения и их применение в качестве ингибиторов daao
EA201390163A1 (ru) Гетеробициклические производные в качетстве ингибиторов hcv
PE20141167A1 (es) Piridopirazinas sustituidas como inhibidores novedosos de ptk
GEP20186880B (en) 2-amino-3, 5, 5-trifluoro-3, 4, 5, 6-tetrahydropyridines as bace1 inhibitors for treatment of alzheimer's disease
EA201400064A1 (ru) Офтальмологическая фармацевтическая композиция для местного применения, которая содержит регорафениб

Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20161028