FR2962531B1 - Methode et dispositif d'imagerie tridimensionnelle par microscopie interferentielle plein champ - Google Patents

Methode et dispositif d'imagerie tridimensionnelle par microscopie interferentielle plein champ

Info

Publication number
FR2962531B1
FR2962531B1 FR1057268A FR1057268A FR2962531B1 FR 2962531 B1 FR2962531 B1 FR 2962531B1 FR 1057268 A FR1057268 A FR 1057268A FR 1057268 A FR1057268 A FR 1057268A FR 2962531 B1 FR2962531 B1 FR 2962531B1
Authority
FR
France
Prior art keywords
sample
interferometer
slice
acquisition
allowing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR1057268A
Other languages
English (en)
Other versions
FR2962531A1 (fr
Inventor
Albert Claude Boccara
Fabrice Harms
Conte Chrestien De Poly Bertrand Le
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LLTECH MANAGEMENT, FR
Original Assignee
LLTECH Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LLTECH Inc filed Critical LLTECH Inc
Priority to US13/808,739 priority Critical patent/US9255785B2/en
Priority to PCT/EP2011/061633 priority patent/WO2012004388A1/fr
Priority to EP11738662.3A priority patent/EP2591389B1/fr
Publication of FR2962531A1 publication Critical patent/FR2962531A1/fr
Application granted granted Critical
Publication of FR2962531B1 publication Critical patent/FR2962531B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01BMEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B9/00Measuring instruments characterised by the use of optical techniques
    • G01B9/02Interferometers
    • G01B9/0209Low-coherence interferometers
    • G01B9/02091Tomographic interferometers, e.g. based on optical coherence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062Arrangements for scanning
    • A61B5/0066Optical coherence imaging
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01BMEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B11/00Measuring arrangements characterised by the use of optical techniques
    • G01B11/24Measuring arrangements characterised by the use of optical techniques for measuring contours or curvatures
    • G01B11/2441Measuring arrangements characterised by the use of optical techniques for measuring contours or curvatures using interferometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01BMEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B9/00Measuring instruments characterised by the use of optical techniques
    • G01B9/02Interferometers
    • G01B9/02041Interferometers characterised by particular imaging or detection techniques
    • G01B9/02048Rough and fine measurement
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01BMEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B9/00Measuring instruments characterised by the use of optical techniques
    • G01B9/02Interferometers
    • G01B9/02055Reduction or prevention of errors; Testing; Calibration
    • G01B9/02056Passive reduction of errors
    • G01B9/02057Passive reduction of errors by using common path configuration, i.e. reference and object path almost entirely overlapping
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02Details
    • G01J3/0205Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
    • G01J3/0208Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using focussing or collimating elements, e.g. lenses or mirrors; performing aberration correction
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02Details
    • G01J3/0205Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
    • G01J3/0237Adjustable, e.g. focussing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02Details
    • G01J3/10Arrangements of light sources specially adapted for spectrometry or colorimetry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28Investigating the spectrum
    • G01J3/2823Imaging spectrometer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28Investigating the spectrum
    • G01J3/45Interferometric spectrometry
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/06Means for illuminating specimens
    • G02B21/08Condensers
    • G02B21/14Condensers affording illumination for phase-contrast observation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/04Arrangements of multiple sensors of the same type
    • A61B2562/046Arrangements of multiple sensors of the same type in a matrix array

Landscapes

  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Optics & Photonics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Microscoopes, Condenser (AREA)
  • Instruments For Measurement Of Length By Optical Means (AREA)
FR1057268A 2010-07-08 2010-09-13 Methode et dispositif d'imagerie tridimensionnelle par microscopie interferentielle plein champ Active FR2962531B1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US13/808,739 US9255785B2 (en) 2010-07-08 2011-07-08 Method and device for high resolution full field interference microscopy
PCT/EP2011/061633 WO2012004388A1 (fr) 2010-07-08 2011-07-08 Procédé et dispositif pour l'imagerie tridimensionnelle par la microscopie interférentielle plein champ
EP11738662.3A EP2591389B1 (fr) 2010-07-08 2011-07-08 Procédé et dispositif pour l'imagerie tridimensionnelle par la microscopie interférentielle plein champ

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36257810P 2010-07-08 2010-07-08

Publications (2)

Publication Number Publication Date
FR2962531A1 FR2962531A1 (fr) 2012-01-13
FR2962531B1 true FR2962531B1 (fr) 2014-01-17

Family

ID=44514659

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1057268A Active FR2962531B1 (fr) 2010-07-08 2010-09-13 Methode et dispositif d'imagerie tridimensionnelle par microscopie interferentielle plein champ

Country Status (4)

Country Link
US (1) US9255785B2 (fr)
EP (1) EP2591389B1 (fr)
FR (1) FR2962531B1 (fr)
WO (1) WO2012004388A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11922623B2 (en) 2020-07-13 2024-03-05 Aquyre Biosciences, Inc. Cellular diagnostic and analysis methods

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Publication number Priority date Publication date Assignee Title
WO2013160890A1 (fr) * 2012-04-23 2013-10-31 Ben-Gurion University Of The Negev Research & Development Authority Tomographie par cohérence optique en plein champ, haute résolution et double mode, à véritable spectroscopie, utilisant des dispositifs à cristaux liquides
US20150185324A1 (en) * 2012-04-27 2015-07-02 Nikon Corporation Laser radar tracking systems
US9677869B2 (en) 2012-12-05 2017-06-13 Perimeter Medical Imaging, Inc. System and method for generating a wide-field OCT image of a portion of a sample
FR3015659B1 (fr) * 2013-12-20 2016-01-29 Centre Nat Rech Scient Appareil et procede de tomographie optique
JP6557229B2 (ja) 2014-07-01 2019-08-07 興和株式会社 断層像撮影装置
JP6413076B2 (ja) 2014-10-01 2018-10-31 パナソニックIpマネジメント株式会社 内層測定方法及び装置
FR3034858B1 (fr) * 2015-04-10 2017-05-26 Lltech Man Procede et systeme d'imagerie par microscopie interferentielle plein champ
JP6808383B2 (ja) * 2015-09-30 2021-01-06 キヤノン株式会社 光干渉断層撮影装置、その制御方法および光干渉断層撮影システム
WO2017057652A1 (fr) * 2015-09-30 2017-04-06 Canon Kabushiki Kaisha Appareil de tomographie à cohérence optique et système de tomographie à cohérence optique
CN109074674B (zh) * 2016-02-26 2023-10-24 南加州大学 具有选择性体积照射和光场检测的优化容积成像
WO2018079326A1 (fr) 2016-10-28 2018-05-03 富士フイルム株式会社 Dispositif d'imagerie tomographique par cohérence optique et procédé de mesure
DE102017101188B4 (de) 2017-01-23 2021-09-30 Carl Zeiss Microscopy Gmbh Mikroskop und Verfahren zum Mikroskopieren einer Probe
CN108982433B (zh) * 2017-06-05 2021-09-03 锐准医光股份有限公司 采用进阶光学干涉显微术的光学切层装置
WO2019014767A1 (fr) 2017-07-18 2019-01-24 Perimeter Medical Imaging, Inc. Récipient d'échantillon pour stabiliser et aligner des échantillons de tissu biologique excisés pour analyse ex vivo
EP4044898A4 (fr) * 2019-10-19 2023-10-18 Apollo Medical Optics, Ltd. Système optique et module objectif d'interférence associé
FR3112866B1 (fr) * 2020-07-22 2022-07-22 Damae Medical Systèmes et procédés d’analyse microscopique d’un échantillon
WO2023084322A1 (fr) * 2021-11-12 2023-05-19 Ap Infosense Limited Système de profileur large bande et procédé permettant de construire un profilé tridimensionnel d'une cible

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US5459564A (en) * 1994-02-18 1995-10-17 Chivers; James T. Apparatus and method for inspecting end faces of optical fibers and optical fiber connectors
ATA107495A (de) 1995-06-23 1996-06-15 Fercher Adolf Friedrich Dr Kohärenz-biometrie und -tomographie mit dynamischem kohärentem fokus
US6690474B1 (en) * 1996-02-12 2004-02-10 Massachusetts Institute Of Technology Apparatus and methods for surface contour measurement
FR2817030B1 (fr) 2000-11-17 2003-03-28 Centre Nat Rech Scient Procede et dispositif d'imagerie microscopique interferentielle d'un objet a haute cadence
CN1320334C (zh) * 2002-03-14 2007-06-06 泰勒·霍布森有限公司 表面成型设备和获得数据方法,数据处理设备及其相关器
DE102004022341A1 (de) * 2004-05-04 2005-12-29 Carl Mahr Holding Gmbh Vorrichtung und Verfahren zur kombinierten interferometrischen und abbildungsbasierten Geometrieerfassung insbesondere in der Mikrosystemtechnik
JP4546209B2 (ja) * 2004-09-30 2010-09-15 株式会社ニデック 眼科装置
KR20080066705A (ko) * 2005-09-29 2008-07-16 더 제너럴 하스피탈 코포레이션 점진적으로 증가하는 분해능을 이용하여 하나 이상의 생물학적 샘플을 관찰 및 분석하기 위한 방법 및 장치
EP1892501A3 (fr) 2006-08-23 2009-10-07 Heliotis AG Microscopie tridimensionnelle colorimétrique
DE102007019679A1 (de) * 2006-11-06 2008-05-15 Carl Zeiss Surgical Gmbh Operationsmikroskop mit OCT-System
JP5058627B2 (ja) 2007-02-26 2012-10-24 株式会社トプコン 眼底観察装置

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11922623B2 (en) 2020-07-13 2024-03-05 Aquyre Biosciences, Inc. Cellular diagnostic and analysis methods

Also Published As

Publication number Publication date
EP2591389A1 (fr) 2013-05-15
US9255785B2 (en) 2016-02-09
WO2012004388A1 (fr) 2012-01-12
EP2591389B1 (fr) 2018-06-06
US20130107275A1 (en) 2013-05-02
FR2962531A1 (fr) 2012-01-13

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