FR2928654B1 - Equivalent de peau pigmentee fonctionnelle. - Google Patents

Equivalent de peau pigmentee fonctionnelle. Download PDF

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Publication number
FR2928654B1
FR2928654B1 FR0851705A FR0851705A FR2928654B1 FR 2928654 B1 FR2928654 B1 FR 2928654B1 FR 0851705 A FR0851705 A FR 0851705A FR 0851705 A FR0851705 A FR 0851705A FR 2928654 B1 FR2928654 B1 FR 2928654B1
Authority
FR
France
Prior art keywords
equivalent
pigmented skin
functional pigmented
functional
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0851705A
Other languages
English (en)
Other versions
FR2928654A1 (fr
Inventor
Christine Duval
Francoise Bernerd
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LOreal SA
Original Assignee
LOreal SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LOreal SA filed Critical LOreal SA
Priority to FR0851705A priority Critical patent/FR2928654B1/fr
Priority to CA2658074A priority patent/CA2658074C/fr
Priority to KR1020090022255A priority patent/KR101132578B1/ko
Priority to CN 200910138703 priority patent/CN101538555B/zh
Priority to JP2009062725A priority patent/JP6113393B2/ja
Priority to US12/382,384 priority patent/US10612004B2/en
Priority to ES09155394.1T priority patent/ES2596811T3/es
Priority to EP09155394.1A priority patent/EP2103687B1/fr
Publication of FR2928654A1 publication Critical patent/FR2928654A1/fr
Priority to JP2016093687A priority patent/JP6240255B2/ja
Application granted granted Critical
Publication of FR2928654B1 publication Critical patent/FR2928654B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
    • C12N5/0698—Skin equivalents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/117—Keratinocyte growth factors (KGF-1, i.e. FGF-7; KGF-2, i.e. FGF-12)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/39—Steroid hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/09—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
    • C12N2502/094—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells keratinocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1323—Adult fibroblasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/52—Fibronectin; Laminin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/54—Collagen; Gelatin

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

L'invention concerne un équivalent de peau in vitro caractérisé en ce qu'il comporte au moins un équivalent d'épiderme et au moins un équivalent de derme, et en ce qu'il comprend des mélanocytes produisant de la mélanine de façon constitutive et des fibroblastes.Elle concerne également un procédé de préparation de l'équivalent de peau.
FR0851705A 2008-03-17 2008-03-17 Equivalent de peau pigmentee fonctionnelle. Expired - Fee Related FR2928654B1 (fr)

Priority Applications (9)

Application Number Priority Date Filing Date Title
FR0851705A FR2928654B1 (fr) 2008-03-17 2008-03-17 Equivalent de peau pigmentee fonctionnelle.
CA2658074A CA2658074C (fr) 2008-03-17 2009-03-12 Equivalent de peau pigmentee fonctionnelle
CN 200910138703 CN101538555B (zh) 2008-03-17 2009-03-16 功能性色素皮肤等同物
JP2009062725A JP6113393B2 (ja) 2008-03-17 2009-03-16 機能的色素沈着皮膚同等物
KR1020090022255A KR101132578B1 (ko) 2008-03-17 2009-03-16 기능적 색소화 피부 대체물
US12/382,384 US10612004B2 (en) 2008-03-17 2009-03-16 Functional pigmented skin equivalent
ES09155394.1T ES2596811T3 (es) 2008-03-17 2009-03-17 Equivalente de piel pigmentada funcional
EP09155394.1A EP2103687B1 (fr) 2008-03-17 2009-03-17 Equivalent de peau pigmentée fonctionnelle
JP2016093687A JP6240255B2 (ja) 2008-03-17 2016-05-09 機能的色素沈着皮膚同等物

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0851705A FR2928654B1 (fr) 2008-03-17 2008-03-17 Equivalent de peau pigmentee fonctionnelle.
FR0851705 2008-03-17

Publications (2)

Publication Number Publication Date
FR2928654A1 FR2928654A1 (fr) 2009-09-18
FR2928654B1 true FR2928654B1 (fr) 2018-04-27

Family

ID=39737084

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0851705A Expired - Fee Related FR2928654B1 (fr) 2008-03-17 2008-03-17 Equivalent de peau pigmentee fonctionnelle.

Country Status (2)

Country Link
CN (1) CN101538555B (fr)
FR (1) FR2928654B1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103983762A (zh) * 2013-02-08 2014-08-13 北京富龙康泰生物技术有限公司 含黑色素细胞的皮肤模型、其构建方法及用途
US9554744B2 (en) * 2013-12-19 2017-01-31 International Business Machines Corporation Mining social media for ultraviolet light exposure analysis
CN104877957B (zh) * 2014-02-28 2018-06-01 上海尚瑞生物医药科技有限公司 一种促进黑色素细胞色素产生的细胞株
US10273549B2 (en) 2016-04-21 2019-04-30 Vitrolabs Inc. Engineered skin equivalent, method of manufacture thereof and products derived therefrom
FR3054449B1 (fr) * 2016-07-29 2018-08-31 L'oreal Equivalent de peau a compartiments dermiques juxtaposes distincts
WO2020111265A1 (fr) * 2018-11-30 2020-06-04 株式会社 資生堂 Modèle de pigmentation de la peau et son procédé de production, et procédé d'évaluation du facteur pour le traitement ou la prévention de la pigmentation de la peau

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1062441C (zh) * 1990-04-24 2001-02-28 奥特克国际公司 复合的活的皮肤等同物及其制备方法
CN1224429C (zh) * 2002-12-04 2005-10-26 曹谊林 人工皮肤移植物及其制备方法
KR100806695B1 (ko) * 2005-11-25 2008-02-27 주식회사 엠씨티티 색소화 질환 치료용 세포치료 약제학적 조성물
FR2903702B1 (fr) * 2006-07-13 2012-10-19 Oreal Equivalent d'epiderme capable de se pigmenter obtenu a partir de cellules de la matrice, procede de preparation et utilisation

Also Published As

Publication number Publication date
FR2928654A1 (fr) 2009-09-18
CN101538555B (zh) 2013-08-21
CN101538555A (zh) 2009-09-23

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