FR2918375B1 - Utilisation d'un support de chromatographie pour reduire la quantite d'adamts13 dans une solution derivee du plasma - Google Patents

Utilisation d'un support de chromatographie pour reduire la quantite d'adamts13 dans une solution derivee du plasma

Info

Publication number
FR2918375B1
FR2918375B1 FR0756303A FR0756303A FR2918375B1 FR 2918375 B1 FR2918375 B1 FR 2918375B1 FR 0756303 A FR0756303 A FR 0756303A FR 0756303 A FR0756303 A FR 0756303A FR 2918375 B1 FR2918375 B1 FR 2918375B1
Authority
FR
France
Prior art keywords
adamts13
plasma
reduce
chromatography medium
derived solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0756303A
Other languages
English (en)
Other versions
FR2918375A1 (fr
Inventor
Francoise Bridey
Roland Schmitthaeusler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LFB SA
Original Assignee
LFB SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0756303A priority Critical patent/FR2918375B1/fr
Application filed by LFB SA filed Critical LFB SA
Priority to BRPI0813742-0A2A priority patent/BRPI0813742A2/pt
Priority to PCT/FR2008/051251 priority patent/WO2009007661A2/fr
Priority to CA002691604A priority patent/CA2691604A1/fr
Priority to AU2008273988A priority patent/AU2008273988A1/en
Priority to EP08806168A priority patent/EP2167657A2/fr
Priority to CN2008800234967A priority patent/CN101918546A/zh
Priority to KR1020107000053A priority patent/KR20100041731A/ko
Priority to JP2010514085A priority patent/JP2010532337A/ja
Priority to US12/667,751 priority patent/US8025803B2/en
Publication of FR2918375A1 publication Critical patent/FR2918375A1/fr
Application granted granted Critical
Publication of FR2918375B1 publication Critical patent/FR2918375B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489—Metalloendopeptidases (3.4.24)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
FR0756303A 2007-07-05 2007-07-05 Utilisation d'un support de chromatographie pour reduire la quantite d'adamts13 dans une solution derivee du plasma Expired - Fee Related FR2918375B1 (fr)

Priority Applications (10)

Application Number Priority Date Filing Date Title
FR0756303A FR2918375B1 (fr) 2007-07-05 2007-07-05 Utilisation d'un support de chromatographie pour reduire la quantite d'adamts13 dans une solution derivee du plasma
JP2010514085A JP2010532337A (ja) 2007-07-05 2008-07-04 血漿からの溶液中のａｄａｍｔｓ１３の量を減少させるためのクロマトグラフィ担体の使用
CA002691604A CA2691604A1 (fr) 2007-07-05 2008-07-04 Utilisation d'un support de chromatographie pour reduire la quantite d'adamts13 dans une solution derivee du plasma
AU2008273988A AU2008273988A1 (en) 2007-07-05 2008-07-04 Use of a chromatography substrate for reducing the amount of ADAMTS13 in a solution derived from plasma
EP08806168A EP2167657A2 (fr) 2007-07-05 2008-07-04 Utilisation d'un support de chromatographie pour reduire la quantite d'adamts13 dans une solution derivee du plasma
CN2008800234967A CN101918546A (zh) 2007-07-05 2008-07-04 层析基质减少来自血浆的溶液中adamts13的量的用途
BRPI0813742-0A2A BRPI0813742A2 (pt) 2007-07-05 2008-07-04 Utilização de um suporte de cromatografia de trocas de íons e processo para reduzir a quantidade de adamts13 presente em uma solução derivada do plasma
PCT/FR2008/051251 WO2009007661A2 (fr) 2007-07-05 2008-07-04 Utilisation d'un support de chromatographie pour reduire la quantite d'adamts13 dans une solution derivee du plasma
KR1020107000053A KR20100041731A (ko) 2007-07-05 2008-07-04 혈장 유래 용액 내의 ａｄａｍｔｓ１３의 함량을 감소시키기 위한 크로마토그래피 기질의 용도
US12/667,751 US8025803B2 (en) 2007-07-05 2008-07-07 Use of a chromatography substrate for reducing the amount of ADAMTS13 in a solution derived from plasma

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0756303A FR2918375B1 (fr) 2007-07-05 2007-07-05 Utilisation d'un support de chromatographie pour reduire la quantite d'adamts13 dans une solution derivee du plasma

Publications (2)

Publication Number Publication Date
FR2918375A1 FR2918375A1 (fr) 2009-01-09
FR2918375B1 true FR2918375B1 (fr) 2009-10-16

Family

ID=39262572

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0756303A Expired - Fee Related FR2918375B1 (fr) 2007-07-05 2007-07-05 Utilisation d'un support de chromatographie pour reduire la quantite d'adamts13 dans une solution derivee du plasma

Country Status (10)

Country Link
US (1) US8025803B2 (fr)
EP (1) EP2167657A2 (fr)
JP (1) JP2010532337A (fr)
KR (1) KR20100041731A (fr)
CN (1) CN101918546A (fr)
AU (1) AU2008273988A1 (fr)
BR (1) BRPI0813742A2 (fr)
CA (1) CA2691604A1 (fr)
FR (1) FR2918375B1 (fr)
WO (1) WO2009007661A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2918375B1 (fr) * 2007-07-05 2009-10-16 Lab Francais Du Fractionnement Utilisation d'un support de chromatographie pour reduire la quantite d'adamts13 dans une solution derivee du plasma
FR2933496B1 (fr) * 2008-07-02 2012-10-05 Lfb Biotechnologies Procede de mesure du taux de facteur vii active dans un echantillon
US8945895B2 (en) * 2009-07-31 2015-02-03 Baxter International Inc. Methods of purifying recombinant ADAMTS13 and other proteins and compositions thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4753983A (en) * 1986-05-07 1988-06-28 Bioprobe International, Inc. Polymeric matrix for affinity chromatography and immobilization of ligands
US6926894B2 (en) * 2000-11-22 2005-08-09 Baxter Aktiengesellschaft Composition exhibiting a von willebrand factor (vWF) protease activity comprising a polypeptide chain with the amino acid sequence AAGGILHLELLV
JP2003284570A (ja) * 2001-04-25 2003-10-07 Chemo Sero Therapeut Res Inst フォンビルブラント因子（ｖＷＦ）切断酵素
US7037658B2 (en) * 2001-08-16 2006-05-02 Regents Of University Of Michigan Methods and compositions for detecting variant ADAMTS13 genes
EP1852442B1 (fr) * 2005-02-14 2012-03-14 Alfresa Pharma Corporation Anticorps pour le dosage de l'activite adamts13 et procede de dosage de l'activite
CA2606351C (fr) * 2005-06-17 2016-12-13 Baxter International Inc. Compositions contenant adamts13, presentant une activite thrombolytique
FR2918375B1 (fr) * 2007-07-05 2009-10-16 Lab Francais Du Fractionnement Utilisation d'un support de chromatographie pour reduire la quantite d'adamts13 dans une solution derivee du plasma
US8945895B2 (en) * 2009-07-31 2015-02-03 Baxter International Inc. Methods of purifying recombinant ADAMTS13 and other proteins and compositions thereof

Also Published As

Publication number Publication date
AU2008273988A1 (en) 2009-01-15
JP2010532337A (ja) 2010-10-07
WO2009007661A2 (fr) 2009-01-15
CN101918546A (zh) 2010-12-15
US8025803B2 (en) 2011-09-27
FR2918375A1 (fr) 2009-01-09
EP2167657A2 (fr) 2010-03-31
US20100193440A1 (en) 2010-08-05
WO2009007661A3 (fr) 2009-02-05
BRPI0813742A2 (pt) 2014-12-30
CA2691604A1 (fr) 2009-01-15
KR20100041731A (ko) 2010-04-22

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Legal Events

Date Code Title Description
TP Transmission of property
ST Notification of lapse

Effective date: 20140331