FR2917414B1 - Facteur vii/viia humain modifie et composition pharmaceutique contenant celui-ci - Google Patents

Facteur vii/viia humain modifie et composition pharmaceutique contenant celui-ci

Info

Publication number
FR2917414B1
FR2917414B1 FR0755775A FR0755775A FR2917414B1 FR 2917414 B1 FR2917414 B1 FR 2917414B1 FR 0755775 A FR0755775 A FR 0755775A FR 0755775 A FR0755775 A FR 0755775A FR 2917414 B1 FR2917414 B1 FR 2917414B1
Authority
FR
France
Prior art keywords
viia
pharmaceutical composition
same
composition containing
factor vii
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0755775A
Other languages
English (en)
Other versions
FR2917414A1 (fr
Inventor
Emmanuel Nony
Sami Chtourou
Nicolas Bihoreau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LFB SA
Original Assignee
LFB SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0755775A priority Critical patent/FR2917414B1/fr
Application filed by LFB SA filed Critical LFB SA
Priority to JP2010511707A priority patent/JP2010529848A/ja
Priority to KR1020097026182A priority patent/KR20100039281A/ko
Priority to EP08805990A priority patent/EP2162147A2/fr
Priority to CA2691110A priority patent/CA2691110A1/fr
Priority to PCT/FR2008/051055 priority patent/WO2008155509A2/fr
Priority to AU2008265021A priority patent/AU2008265021A1/en
Priority to CN200880024853A priority patent/CN101743017A/zh
Priority to BRPI0813372-7A2A priority patent/BRPI0813372A2/pt
Priority to US12/664,733 priority patent/US20110162094A1/en
Priority to TW097122345A priority patent/TW200906851A/zh
Priority to ARP080102572A priority patent/AR067335A1/es
Publication of FR2917414A1 publication Critical patent/FR2917414A1/fr
Application granted granted Critical
Publication of FR2917414B1 publication Critical patent/FR2917414B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6437—Coagulation factor VIIa (3.4.21.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21021—Coagulation factor VIIa (3.4.21.21)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
FR0755775A 2007-06-15 2007-06-15 Facteur vii/viia humain modifie et composition pharmaceutique contenant celui-ci Expired - Fee Related FR2917414B1 (fr)

Priority Applications (12)

Application Number Priority Date Filing Date Title
FR0755775A FR2917414B1 (fr) 2007-06-15 2007-06-15 Facteur vii/viia humain modifie et composition pharmaceutique contenant celui-ci
BRPI0813372-7A2A BRPI0813372A2 (pt) 2007-06-15 2008-06-12 Fator vii/viia humano modificado, ácido nucléico, vetor de expressão, célula transformada por um ácido nucleico, organismo não humano geneticamente modificado, processo de fabricação de um fator vii/viia, composição de fator vii/viia, composição farmacêutica, e, utilização de um fator vii/viia.
EP08805990A EP2162147A2 (fr) 2007-06-15 2008-06-12 Facteur vii/viia humain modifie et composition pharmaceutique contenant celui-ci
CA2691110A CA2691110A1 (fr) 2007-06-15 2008-06-12 Facteur vii/viia humain modifie et composition pharmaceutique contenant celui-ci
PCT/FR2008/051055 WO2008155509A2 (fr) 2007-06-15 2008-06-12 Facteur vii/viia humain modifie et composition pharmaceutique contenant celui-ci
AU2008265021A AU2008265021A1 (en) 2007-06-15 2008-06-12 Modified human factor VII/VIIa and pharmaceutical composition containing same
JP2010511707A JP2010529848A (ja) 2007-06-15 2008-06-12 修飾したヒト因子ＶＩＩ／ＶＩＩａと、それを含む医薬組成物
KR1020097026182A KR20100039281A (ko) 2007-06-15 2008-06-12 변형된 인간 인자 Ⅶ／Ⅶａ 및 이를 함유하는 약학 조성물
US12/664,733 US20110162094A1 (en) 2007-06-15 2008-06-12 Modified human factor vii/viia and pharmaceutical composition containing the same
CN200880024853A CN101743017A (zh) 2007-06-15 2008-06-12 经修饰的人因子VII/VIIa和包含它的药物组合物
TW097122345A TW200906851A (en) 2007-06-15 2008-06-13 Modified human factor VII/VIIa and pharmaceutical composition comprising the same
ARP080102572A AR067335A1 (es) 2007-06-15 2008-06-17 Factor vii/viia humano modificado y composicion farmaceutica que lo contiene

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0755775A FR2917414B1 (fr) 2007-06-15 2007-06-15 Facteur vii/viia humain modifie et composition pharmaceutique contenant celui-ci

Publications (2)

Publication Number Publication Date
FR2917414A1 FR2917414A1 (fr) 2008-12-19
FR2917414B1 true FR2917414B1 (fr) 2012-07-13

Family

ID=38702010

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0755775A Expired - Fee Related FR2917414B1 (fr) 2007-06-15 2007-06-15 Facteur vii/viia humain modifie et composition pharmaceutique contenant celui-ci

Country Status (12)

Country Link
US (1) US20110162094A1 (fr)
EP (1) EP2162147A2 (fr)
JP (1) JP2010529848A (fr)
KR (1) KR20100039281A (fr)
CN (1) CN101743017A (fr)
AR (1) AR067335A1 (fr)
AU (1) AU2008265021A1 (fr)
BR (1) BRPI0813372A2 (fr)
CA (1) CA2691110A1 (fr)
FR (1) FR2917414B1 (fr)
TW (1) TW200906851A (fr)
WO (1) WO2008155509A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2554161A1 (fr) 2011-08-02 2013-02-06 LFB Biotechnologies Composition pharmaceutique comprenant factor VII encapsulé dans des micelles

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE122007000007I2 (de) * 1986-04-09 2010-12-30 Genzyme Corp Genetisch transformierte Tiere, die ein gewünschtes Protein in Milch absondern
DK323587D0 (da) * 1987-06-25 1987-06-25 Novo Industri As Protein
US5580560A (en) * 1989-11-13 1996-12-03 Novo Nordisk A/S Modified factor VII/VIIa
FR2684999A1 (fr) * 1991-12-16 1993-06-18 Aquitaine Dev Transf Sanguine Procede de fabrication d'un concentre de facteur vii active de haute purete essentiellement depourvu des facteurs vitamine k dependants et des facteurs viiic et viiicag.
US7173000B2 (en) * 2000-11-09 2007-02-06 The Scripps Research Institute Modified factor VIIa

Also Published As

Publication number Publication date
AU2008265021A1 (en) 2008-12-24
WO2008155509A3 (fr) 2009-02-19
CA2691110A1 (fr) 2008-12-24
JP2010529848A (ja) 2010-09-02
WO2008155509A2 (fr) 2008-12-24
AR067335A1 (es) 2009-10-07
US20110162094A1 (en) 2011-06-30
BRPI0813372A2 (pt) 2014-12-30
KR20100039281A (ko) 2010-04-15
EP2162147A2 (fr) 2010-03-17
CN101743017A (zh) 2010-06-16
FR2917414A1 (fr) 2008-12-19
TW200906851A (en) 2009-02-16
WO2008155509A9 (fr) 2010-04-08

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Legal Events

Date Code Title Description
TP Transmission of property
ST Notification of lapse

Effective date: 20140228