FR2878522B1 - Nouveaux inhibiteurs specifiques de la caspas-10 - Google Patents
Nouveaux inhibiteurs specifiques de la caspas-10Info
- Publication number
- FR2878522B1 FR2878522B1 FR0412765A FR0412765A FR2878522B1 FR 2878522 B1 FR2878522 B1 FR 2878522B1 FR 0412765 A FR0412765 A FR 0412765A FR 0412765 A FR0412765 A FR 0412765A FR 2878522 B1 FR2878522 B1 FR 2878522B1
- Authority
- FR
- France
- Prior art keywords
- caspas
- specific inhibitors
- new specific
- new
- inhibitors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
- C07C57/38—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0412765A FR2878522B1 (fr) | 2004-12-01 | 2004-12-01 | Nouveaux inhibiteurs specifiques de la caspas-10 |
AU2005312137A AU2005312137B2 (en) | 2004-12-01 | 2005-11-02 | Novel specific caspase-10 inhibitors |
US11/791,922 US7829721B2 (en) | 2004-12-01 | 2005-11-02 | Specific caspase-10 inhibitors |
PCT/EP2005/011686 WO2006058592A1 (fr) | 2004-12-01 | 2005-11-02 | Nouveaux inhibiteurs specifiques de la caspase-10 |
CA2589497A CA2589497C (fr) | 2004-12-01 | 2005-11-02 | Nouveaux inhibiteurs specifiques de la caspase-10 |
EP05808239.7A EP1817031B1 (fr) | 2004-12-01 | 2005-11-02 | Inhibiteurs de la caspase-10 pour la prevention et le traitement de la retinopathie |
JP2007543716A JP4989482B2 (ja) | 2004-12-01 | 2005-11-02 | 新規特異的カスパーゼ−10阻害剤 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0412765A FR2878522B1 (fr) | 2004-12-01 | 2004-12-01 | Nouveaux inhibiteurs specifiques de la caspas-10 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2878522A1 FR2878522A1 (fr) | 2006-06-02 |
FR2878522B1 true FR2878522B1 (fr) | 2008-04-18 |
Family
ID=34953773
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR0412765A Expired - Fee Related FR2878522B1 (fr) | 2004-12-01 | 2004-12-01 | Nouveaux inhibiteurs specifiques de la caspas-10 |
Country Status (7)
Country | Link |
---|---|
US (1) | US7829721B2 (fr) |
EP (1) | EP1817031B1 (fr) |
JP (1) | JP4989482B2 (fr) |
AU (1) | AU2005312137B2 (fr) |
CA (1) | CA2589497C (fr) |
FR (1) | FR2878522B1 (fr) |
WO (1) | WO2006058592A1 (fr) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010042652A2 (fr) | 2008-10-08 | 2010-04-15 | Amira Pharmaceuticals, Inc. | Antagonistes hétéroalkyl biphényle des récepteurs de la prostaglandine d2 |
US20110120915A1 (en) * | 2009-11-24 | 2011-05-26 | Chevron U.S.A. Inc. | Hydrogenation of solid carbonaceous materials using mixed catalysts |
CN110542675B (zh) * | 2019-09-30 | 2021-12-14 | 广州市锐博生物科技有限公司 | 细胞凋亡检测方法及细胞凋亡检测试剂盒 |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE366296B (fr) | 1967-12-20 | 1974-04-22 | Ciba Geigy Ag | |
JPS56125333A (en) | 1980-03-07 | 1981-10-01 | Nippon Shinyaku Co Ltd | Phenylacetic acid derivative and its preparation |
JPS56125339A (en) * | 1980-03-07 | 1981-10-01 | Nippon Shinyaku Co Ltd | Preparation of phenylacetic acid derivative |
JPS56125338A (en) | 1980-03-07 | 1981-10-01 | Nippon Shinyaku Co Ltd | Phenylacetic acid derivative |
DE3026402A1 (de) | 1980-07-11 | 1982-02-04 | Syntex Corp., Palo Alto, Calif. | Die verwendung analgetischer und nicht-hormonaler, entzuendungshemmender mittel bei der behandlung von mikrovaskulaeren erkrankungen |
US5270317A (en) * | 1990-03-20 | 1993-12-14 | Elf Sanofi | N-substituted heterocyclic derivatives, their preparation and the pharmaceutical compositions in which they are present |
IL104755A0 (en) | 1992-02-17 | 1993-06-10 | Ciba Geigy Ag | Treatment of glaucoma |
ZA931062B (en) * | 1992-02-17 | 1993-08-17 | Ciba Geigy | Compositions for the treatment of glaucoma. |
US6398758B1 (en) * | 1999-02-16 | 2002-06-04 | Stephen C. Jacobsen | Medicament delivery system |
US6304786B1 (en) * | 1999-03-29 | 2001-10-16 | Cardiac Pacemakers, Inc. | Implantable lead with dissolvable coating for improved fixation and extraction |
ATE266623T1 (de) * | 1999-08-06 | 2004-05-15 | Vertex Pharma | Caspase inhibitoren und deren verwendung |
WO2001039792A2 (fr) | 1999-12-03 | 2001-06-07 | Alcon Universal Ltd. | Utilisation d'inhibiteurs de caspase 9 pour traiter une pathologie oculaire nerveuse |
WO2001081312A2 (fr) * | 2000-04-24 | 2001-11-01 | Merck Frosst Canada & Co. | Methode de traitement se basant sur l'utilisation de derives de phenyle et de biaryle comme inhibiteurs de prostaglandine e |
FR2815541B1 (fr) | 2000-10-24 | 2008-02-29 | Lipha | Utilisation d'inhibiteurs de l'apoptose des pericytes pour le traitement et/ou la prevention de la retinopathie diabetique |
US20020103526A1 (en) * | 2000-12-15 | 2002-08-01 | Tom Steinke | Protective coating for stent |
GB2388209C (en) * | 2001-12-20 | 2005-08-23 | Canon Kk | Control apparatus |
US20040034064A1 (en) * | 2002-08-06 | 2004-02-19 | Kuduk Scott D. | 2-(biarylalkyl)amino-3-(alkanoylamino)pyridine derivatives |
MXPA05005409A (es) * | 2002-11-21 | 2005-08-03 | Neurosearch As | Derivados de arilureido y su uso medico. |
US7314480B2 (en) * | 2003-02-27 | 2008-01-01 | Boston Scientific Scimed, Inc. | Rotating balloon expandable sheath bifurcation delivery |
US7284401B2 (en) * | 2004-01-12 | 2007-10-23 | Boston Scientific Scimed, Inc. | Stent reducing system and device |
US7225518B2 (en) * | 2004-02-23 | 2007-06-05 | Boston Scientific Scimed, Inc. | Apparatus for crimping a stent assembly |
US8535702B2 (en) * | 2005-02-01 | 2013-09-17 | Boston Scientific Scimed, Inc. | Medical devices having porous polymeric regions for controlled drug delivery and regulated biocompatibility |
WO2007015761A2 (fr) * | 2005-07-21 | 2007-02-08 | Fmc Biopolymer As | Dispositifs medicaux revetus d'un revetement biocompatible a dissolution rapide |
-
2004
- 2004-12-01 FR FR0412765A patent/FR2878522B1/fr not_active Expired - Fee Related
-
2005
- 2005-11-02 JP JP2007543716A patent/JP4989482B2/ja not_active Expired - Fee Related
- 2005-11-02 CA CA2589497A patent/CA2589497C/fr not_active Expired - Fee Related
- 2005-11-02 US US11/791,922 patent/US7829721B2/en not_active Expired - Fee Related
- 2005-11-02 WO PCT/EP2005/011686 patent/WO2006058592A1/fr active Application Filing
- 2005-11-02 AU AU2005312137A patent/AU2005312137B2/en not_active Ceased
- 2005-11-02 EP EP05808239.7A patent/EP1817031B1/fr not_active Not-in-force
Also Published As
Publication number | Publication date |
---|---|
CA2589497A1 (fr) | 2006-06-08 |
FR2878522A1 (fr) | 2006-06-02 |
JP2008521841A (ja) | 2008-06-26 |
WO2006058592A1 (fr) | 2006-06-08 |
AU2005312137A1 (en) | 2006-06-08 |
EP1817031B1 (fr) | 2014-05-21 |
CA2589497C (fr) | 2013-08-20 |
US20080255173A1 (en) | 2008-10-16 |
AU2005312137B2 (en) | 2011-05-26 |
US7829721B2 (en) | 2010-11-09 |
JP4989482B2 (ja) | 2012-08-01 |
EP1817031A1 (fr) | 2007-08-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CY2022001I2 (el) | Παραγωγα του uk-2a | |
CY2013042I1 (el) | Αναστολεις πυριδυλιου της σηματοδοτησης hedgehog | |
LTPA2017004I1 (lt) | Chinazolinonai kaip žmogaus fosfatidilinozitol-3-kinazės-delta inhibitoriai | |
DK1940839T3 (da) | Pyridopyrimidione Inhibitors of P13Ka | |
DK1720866T3 (da) | Fremgangsmåde | |
CY2014011I1 (el) | Χορηγηση αναστολεων διπεπτιδυλοπεπτιδασης | |
ITMI20050191A1 (it) | Struttura di fet ad alette | |
DK1802872T3 (da) | Rörledning | |
ATE400271T1 (de) | Aryl-pyridinderivate als 11-beta-hsd1-hemmer | |
ATE423121T1 (de) | Diphenylimidazopyrimidin- und -imidazolamine als b-sekretase-inhibitoren | |
ATE420076T1 (de) | Indozolonderivate als 11b-hsd1-inhibitoren | |
DE602004018837D1 (de) | Ptidase-iv-inhibitoren | |
DK1831605T3 (da) | Fremgangsmåde vedrørende forbrænding | |
FR2873694B1 (fr) | Nouveaux aza-indoles inhibiteurs de la mtp et apob | |
NO20043305D0 (no) | Preparation of lodixanol | |
IS7963A (is) | Efnasambönd með hamlandi virkni gegn prólýlólígópeptíðasa | |
FR2884820B1 (fr) | Nouveaux inhibiteurs specifiques de la caspase-10 | |
ITMI20041626A1 (it) | Inibitori della chinurenina-ammino-trasferasi | |
FR2878522B1 (fr) | Nouveaux inhibiteurs specifiques de la caspas-10 | |
DK1962960T3 (da) | Fremgangsmåde til mikornisering | |
FR2877833B1 (fr) | Correcteur de lordoses | |
ITVR20040028A1 (it) | Struttura di longherone | |
AT7230U3 (de) | Wasserpfeife | |
DOP2004000824A (es) | Nuevos derivados de 2-piridinacarboxamida | |
SE0400528D0 (sv) | Methods for protein purification |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |
Effective date: 20140829 |