FR2869903A1 - Nouveaux composes bi-aromatiques activateurs des recepteurs de type ppary, leur procede de preparation et leur utilisation dans les compositions cosmetiques ou pharmaceutiques - Google Patents
Nouveaux composes bi-aromatiques activateurs des recepteurs de type ppary, leur procede de preparation et leur utilisation dans les compositions cosmetiques ou pharmaceutiquesInfo
- Publication number
- FR2869903A1 FR2869903A1 FR0404913A FR0404913A FR2869903A1 FR 2869903 A1 FR2869903 A1 FR 2869903A1 FR 0404913 A FR0404913 A FR 0404913A FR 0404913 A FR0404913 A FR 0404913A FR 2869903 A1 FR2869903 A1 FR 2869903A1
- Authority
- FR
- France
- Prior art keywords
- ureido
- new
- substituted biphenyl
- biphenyl derivatives
- activated receptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/42—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Vascular Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
Abstract
L'invention concerne de nouveaux composés bi-aromatiques qui répondent à la formule générale (I) suivante :ainsi que leur méthode de préparation, et leur utilisation dans des compositions pharmaceutiques destinées à un usage en médecine humaine ou vétérinaire, notamment en dermatologie, ainsi que dans le domaine des maladies cardio-vasculaires, des maladies immunitaires et/ou des maladies liées au métabolisme des lipides, ou bien encore dans des compositions cosmétiques.
Priority Applications (23)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0404913A FR2869903B1 (fr) | 2004-05-06 | 2004-05-06 | Nouveaux composes bi-aromatiques activateurs des recepteurs de type ppary, leur procede de preparation et leur utilisation dans les compositions cosmetiques ou pharmaceutiques |
RU2006143054/04A RU2006143054A (ru) | 2004-05-06 | 2005-04-29 | Новые биароматические соединения, которые активируют рецепторы ppary-типа, способы их получения и их применение в косметике или в фармацевтических композициях |
CNA2005800145211A CN1950335A (zh) | 2004-05-06 | 2005-04-29 | 活化PPAR-γ型受体的新型联芳族化合物、它们的制备方法以及它们在化妆用或药用组合物中的用途 |
AT05743226T ATE458468T1 (de) | 2004-05-06 | 2005-04-29 | Biaromatische verbindungen, die rezeptoren des typs ppar(gamma) aktivieren, verfahren zu deren herstellung und deren verwendung in kosmetischen oder pharmazeutischen zusammensetzungen |
PL05743226T PL1742608T3 (pl) | 2004-05-06 | 2005-04-29 | Biaromatyczne związki, które aktywują receptory typu PPAR(gamma), sposób ich wytwarzania i ich zastosowanie w kompozycjach kosmetycznych lub farmaceutycznych |
KR1020067023286A KR20070015566A (ko) | 2004-05-06 | 2005-04-29 | PPARγ-형 수용체를 활성화하는 신규한 이방향족화합물, 그의 제조 방법 및 미용 또는 약학 조성물에서그의 용도 |
DK05743226.2T DK1742608T3 (da) | 2004-05-06 | 2005-04-29 | Biaromatiske forbindelser, som aktiverer receptorer af typen PPAR(gamma), fremgangsmåde til fremstilling af disse og deres anvendelse i kosmetik eller farmaceutiske sammensætninger |
BRPI0510223-5A BRPI0510223A (pt) | 2004-05-06 | 2005-04-29 | compostos, composição cosmética, uso cosmético, uso de um composto, composição farmacêutica e processos para a sìntese de compostos |
ES05743226T ES2340178T3 (es) | 2004-05-06 | 2005-04-29 | Compuestos biaromaticos que son activadores de los receptores astivados tipo ppar (gamma), su proceso de preparacion y su utilizacion en composiciones cosmeticas o farmaceuticas. |
EP05743226A EP1742608B1 (fr) | 2004-05-06 | 2005-04-29 | Composes biaromatiques activant des recepteurs de type ppar(gamma), leur processus de preparation et leur utilisation dans des compositions cosmetiques ou pharmaceutiques |
MXPA06012679A MXPA06012679A (es) | 2004-05-06 | 2005-04-29 | Nuevos compuestos biaromaticos que activan receptores tipo ppar (gama), procedimiento de preparacion y uso en composiciones cosmeticas o farmaceuticas. |
CA002563955A CA2563955A1 (fr) | 2004-05-06 | 2005-04-29 | Nouveaux composes biaromatiques activant des recepteurs de type-ppar.gamma., leur processus de preparation et leur utilisation dans des compositions cosmetiques ou pharmaceutiques |
SI200530933T SI1742608T1 (sl) | 2004-05-06 | 2005-04-29 | Bi-aromatiŽŤne spojine, ki aktivirajo receptorje tipa PPAR(GAMA), postopek njihovih izdelav in njihova uporaba v kozmetiŽŤnih ali farmacevtskih zmeseh |
PCT/EP2005/005797 WO2005108352A1 (fr) | 2004-05-06 | 2005-04-29 | Nouveaux composes biaromatiques activant des recepteurs de type ppar$g(g), leur processus de preparation et leur utilisation dans des compositions cosmetiques ou pharmaceutiques |
AU2005240345A AU2005240345A1 (en) | 2004-05-06 | 2005-04-29 | Novel biaromatic compounds which activate PPARgamma-type receptors, their process of preparation and their use in cosmetic or pharmaceutical compositions |
DE602005019555T DE602005019555D1 (de) | 2004-05-06 | 2005-04-29 | Biaromatische verbindungen, die rezeptoren des typs ppar(gamma) aktivieren, verfahren zu deren herstellung und deren verwendung in kosmetischen oder pharmazeutischen zusammensetzungen |
JP2007512127A JP2007536331A (ja) | 2004-05-06 | 2005-04-29 | PPARγタイプレセプターを活性化する新規二芳香族化合物、それらの調製方法、及び化粧品組成物若しくは製薬組成物におけるそれらの使用 |
PT05743226T PT1742608E (pt) | 2004-05-06 | 2005-04-29 | Novos compostos biaromáticos que activam receptores do tipo pparγ, o processo para sua preparação e sua utilização em composições cosméticas ou farmacêuticas |
ARP050101786A AR048884A1 (es) | 2004-05-06 | 2005-05-04 | Compuestos biaromaticos activadores de los receptores de tipo ppar gamma |
US11/592,276 US7626054B2 (en) | 2004-05-06 | 2006-11-03 | Biaromatic compounds which activate PPARγ-type receptors and cosmetic/pharmaceutical compositions comprised thereof |
ZA200609806A ZA200609806B (en) | 2004-05-06 | 2006-11-23 | Novel biaromatic compounds which activate PPARy-type receptors, their process of preparation and their use in cosmetic or pharmaceutical compositions |
US12/588,267 US7973063B2 (en) | 2004-05-06 | 2009-10-09 | Methods for activating PPAR gamma-type receptors |
CY20101100349T CY1110021T1 (el) | 2004-05-06 | 2010-04-16 | ΔΙΑΡΩΜΑΤΙΚΕΣ ΕΝΩΣΕΙΣ ΟΙ ΟΠΟΙΕΣ ΕΝΕΡΓΟΠΟΙΟΥΝ ΥΠΟΔΟΧΕΙΣ ΤΟΥ ΤΥΠΟΥ PPARγ, ΜΕΘΟΔΟΣ ΠΑΡΑΣΚΕΥΗΣ ΑΥΤΩΝ ΚΑΙ Η ΧΡΗΣΗ ΤΟΥΣ ΣΤΗΝ ΚΟΣΜΗΤΙΚΗ Ή ΣΕ ΦΑΡΜΑΚΕΥΤΙΚΕΣ ΣΥΝΘΕΣΕΙΣ |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0404913A FR2869903B1 (fr) | 2004-05-06 | 2004-05-06 | Nouveaux composes bi-aromatiques activateurs des recepteurs de type ppary, leur procede de preparation et leur utilisation dans les compositions cosmetiques ou pharmaceutiques |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2869903A1 true FR2869903A1 (fr) | 2005-11-11 |
FR2869903B1 FR2869903B1 (fr) | 2006-06-23 |
Family
ID=34945757
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR0404913A Expired - Fee Related FR2869903B1 (fr) | 2004-05-06 | 2004-05-06 | Nouveaux composes bi-aromatiques activateurs des recepteurs de type ppary, leur procede de preparation et leur utilisation dans les compositions cosmetiques ou pharmaceutiques |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP1742608B1 (fr) |
JP (1) | JP2007536331A (fr) |
KR (1) | KR20070015566A (fr) |
CN (1) | CN1950335A (fr) |
AR (1) | AR048884A1 (fr) |
AT (1) | ATE458468T1 (fr) |
AU (1) | AU2005240345A1 (fr) |
BR (1) | BRPI0510223A (fr) |
CA (1) | CA2563955A1 (fr) |
DK (1) | DK1742608T3 (fr) |
ES (1) | ES2340178T3 (fr) |
FR (1) | FR2869903B1 (fr) |
PL (1) | PL1742608T3 (fr) |
PT (1) | PT1742608E (fr) |
RU (1) | RU2006143054A (fr) |
SI (1) | SI1742608T1 (fr) |
WO (1) | WO2005108352A1 (fr) |
ZA (1) | ZA200609806B (fr) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11241420B2 (en) | 2007-04-11 | 2022-02-08 | Omeros Corporation | Compositions and methods for prophylaxis and treatment of addictions |
US20160331729A9 (en) | 2007-04-11 | 2016-11-17 | Omeros Corporation | Compositions and methods for prophylaxis and treatment of addictions |
EP2991967A1 (fr) * | 2013-03-20 | 2016-03-09 | F. Hoffmann-La Roche AG | Dérivés d'urée et leurs utilisations en tant qu'inhibiteurs de la protéine de liaison à un acide gras (fabp) |
BR112015024113A2 (pt) | 2013-03-20 | 2017-07-18 | Hoffmann La Roche | derivados de uréia e seu uso como inibidores da proteína de ligação de ácido graxo (fabp) |
CN104844476B (zh) * | 2015-04-03 | 2016-08-24 | 李凌 | 一种医药中间体联苯类化合物的合成方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002012210A1 (fr) * | 2000-08-08 | 2002-02-14 | Galderma Research & Development | Derives de biphenyle et leur utilisation comme activateurs des recepteurs ppar-gamma |
WO2004048351A2 (fr) * | 2002-11-25 | 2004-06-10 | Galderma Research & Development, S.N.C. | Nouveaux composes bi-aromatiques qui activent des recepteurs de type ppar$g(y), et leur utilisation dans des compositions cosmetiques ou pharmaceutiques |
-
2004
- 2004-05-06 FR FR0404913A patent/FR2869903B1/fr not_active Expired - Fee Related
-
2005
- 2005-04-29 WO PCT/EP2005/005797 patent/WO2005108352A1/fr active Application Filing
- 2005-04-29 BR BRPI0510223-5A patent/BRPI0510223A/pt not_active Application Discontinuation
- 2005-04-29 AU AU2005240345A patent/AU2005240345A1/en not_active Abandoned
- 2005-04-29 DK DK05743226.2T patent/DK1742608T3/da active
- 2005-04-29 EP EP05743226A patent/EP1742608B1/fr active Active
- 2005-04-29 PT PT05743226T patent/PT1742608E/pt unknown
- 2005-04-29 CN CNA2005800145211A patent/CN1950335A/zh active Pending
- 2005-04-29 JP JP2007512127A patent/JP2007536331A/ja active Pending
- 2005-04-29 KR KR1020067023286A patent/KR20070015566A/ko not_active Application Discontinuation
- 2005-04-29 SI SI200530933T patent/SI1742608T1/sl unknown
- 2005-04-29 RU RU2006143054/04A patent/RU2006143054A/ru unknown
- 2005-04-29 CA CA002563955A patent/CA2563955A1/fr not_active Abandoned
- 2005-04-29 PL PL05743226T patent/PL1742608T3/pl unknown
- 2005-04-29 AT AT05743226T patent/ATE458468T1/de active
- 2005-04-29 ES ES05743226T patent/ES2340178T3/es active Active
- 2005-05-04 AR ARP050101786A patent/AR048884A1/es unknown
-
2006
- 2006-11-23 ZA ZA200609806A patent/ZA200609806B/en unknown
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002012210A1 (fr) * | 2000-08-08 | 2002-02-14 | Galderma Research & Development | Derives de biphenyle et leur utilisation comme activateurs des recepteurs ppar-gamma |
WO2004048351A2 (fr) * | 2002-11-25 | 2004-06-10 | Galderma Research & Development, S.N.C. | Nouveaux composes bi-aromatiques qui activent des recepteurs de type ppar$g(y), et leur utilisation dans des compositions cosmetiques ou pharmaceutiques |
Also Published As
Publication number | Publication date |
---|---|
EP1742608A1 (fr) | 2007-01-17 |
ATE458468T1 (de) | 2010-03-15 |
PT1742608E (pt) | 2010-04-27 |
JP2007536331A (ja) | 2007-12-13 |
DK1742608T3 (da) | 2010-05-17 |
RU2006143054A (ru) | 2008-06-20 |
ES2340178T3 (es) | 2010-05-31 |
AU2005240345A1 (en) | 2005-11-17 |
EP1742608B1 (fr) | 2010-02-24 |
ZA200609806B (en) | 2007-12-27 |
PL1742608T3 (pl) | 2010-07-30 |
BRPI0510223A (pt) | 2007-10-23 |
FR2869903B1 (fr) | 2006-06-23 |
SI1742608T1 (sl) | 2010-04-30 |
CN1950335A (zh) | 2007-04-18 |
KR20070015566A (ko) | 2007-02-05 |
AR048884A1 (es) | 2006-06-07 |
CA2563955A1 (fr) | 2005-11-17 |
WO2005108352A1 (fr) | 2005-11-17 |
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