FR2869615A1 - Derives de l'acide butanoique, procedes pour leur preparation, compositions pharmaceutiques les contenant et leurs applications therapeutiques - Google Patents
Derives de l'acide butanoique, procedes pour leur preparation, compositions pharmaceutiques les contenant et leurs applications therapeutiquesInfo
- Publication number
- FR2869615A1 FR2869615A1 FR0404711A FR0404711A FR2869615A1 FR 2869615 A1 FR2869615 A1 FR 2869615A1 FR 0404711 A FR0404711 A FR 0404711A FR 0404711 A FR0404711 A FR 0404711A FR 2869615 A1 FR2869615 A1 FR 2869615A1
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- pharmaceutical compositions
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- acid derivatives
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- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/24—Radicals substituted by oxygen atoms
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
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- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
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- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
- C07D311/14—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 6 and unsubstituted in position 7
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
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- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
- C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
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- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
- C07D311/18—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted otherwise than in position 3 or 7
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
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- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
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-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
- C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
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- C07D311/42—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4
- C07D311/44—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3
- C07D311/54—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3 substituted in the carbocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/42—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4
- C07D311/56—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 without hydrogen atoms in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/74—Benzo[b]pyrans, hydrogenated in the carbocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/76—Benzo[c]pyrans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
- C07D317/64—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
- C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
- C07D327/04—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/28—Halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/56—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Quinoline Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Furan Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Pyrane Compounds (AREA)
Abstract
Composés de formule (I):dans laquelle R, R1 et R2 sont tels que définis dans la description, leur utilisation pour le traitement de dyslipidémies, de l'athérosclérose et du diabète,les compositions pharmaceutiques qui les contiennent etles procédés de préparation de ces composés.
Priority Applications (16)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0404711A FR2869615B1 (fr) | 2004-05-03 | 2004-05-03 | Derives de l'acide butanoique, procedes pour leur preparation, compositions pharmaceutiques les contenant et leurs applications therapeutiques |
JP2007511903A JP5295560B2 (ja) | 2004-05-03 | 2005-04-06 | ブタン酸誘導体、その調製方法、それらを含む医薬組成物およびその治療用途 |
US11/579,362 US7678831B2 (en) | 2004-05-03 | 2005-04-06 | Butanoic acid derivatives, processes for the preparation thereof, pharmaceutical compositions comprising them, and therapeutic applications thereof |
EP05729043A EP1742927B1 (fr) | 2004-05-03 | 2005-04-06 | Derives de l'acide butanoique, leurs procedes de preparation, compositions pharmaceutiques les contenant, et leurs applications therapeutiques |
PT05729043T PT1742927E (pt) | 2004-05-03 | 2005-04-06 | Derivados do ácido butanóico, processos para a sua preparação, composições farmacêuticas que os contêm, e suas aplicações terapêuticas |
AT05729043T ATE503749T1 (de) | 2004-05-03 | 2005-04-06 | Buttersäurederivate, verfahren zu deren herstellung, pharmazeutische zusammensetzungen, die diese enthalten, und therapeutische anwendungen davon |
CA2565184A CA2565184C (fr) | 2004-05-03 | 2005-04-06 | Derives de l'acide butanoique, leurs procedes de preparation, compositions pharmaceutiques les contenant, et leurs applications therapeutiques |
DE602005027194T DE602005027194D1 (de) | 2004-05-03 | 2005-04-06 | Buttersäurederivate, verfahren zu deren herstellung, pharmazeutische zusammensetzungen, die diese enthalten, und therapeutische anwendungen davon |
SI200531318T SI1742927T1 (sl) | 2004-05-03 | 2005-04-06 | Derivati butanojske kisline, postopki za pripravo le-teh, farmacevtski sestavki, ki jih vsebujejo in terapevtske uporabe le-teh |
ES05729043T ES2364150T3 (es) | 2004-05-03 | 2005-04-06 | Derivados del ácido butanoico, procesos para su preparación, composiciones farmacéuticas que los comprenden y sus aplicaciones terapéuticas. |
AU2005238143A AU2005238143B2 (en) | 2004-05-03 | 2005-04-06 | Butanoic acid derivatives, processes for the preparation thereof, pharmaceutical compositions comprising them, and therapeutic applications threreof |
PCT/EP2005/003607 WO2005105764A1 (fr) | 2004-05-03 | 2005-04-06 | Derives de l'acide butanoique, leurs procedes de preparation, compositions pharmaceutiques les contenant, et leurs applications therapeutiques |
DK05729043.9T DK1742927T3 (da) | 2004-05-03 | 2005-04-06 | Butanonsyrederivater, fremgangsmåder til fremstilling deraf, farmaceutiske præparater omfattende dem, og farmaceutiske applikationer deraf |
PL05729043T PL1742927T3 (pl) | 2004-05-03 | 2005-04-06 | Pochodne kwasu butanowego, sposoby ich otrzymywania, kompozycje farmaceutyczne zawierające takie pochodne i terapeutyczne zastosowanie takich pochodnych |
ARP050101761A AR050154A1 (es) | 2004-05-03 | 2005-05-03 | Derivados de acido butanoico, procedimientos para su preparacion y composiciones farmaceuticas que los comprenden |
CY20111100577T CY1111574T1 (el) | 2004-05-03 | 2011-06-16 | Παραγωγα βουτανοϊκου οξεος, διαδικασιες για την παρασκευη τους, φαρμακευτικες συνθεσεις που τα περιλαμβανουν και θεραπευτικες εφαρμογες αυτων |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0404711A FR2869615B1 (fr) | 2004-05-03 | 2004-05-03 | Derives de l'acide butanoique, procedes pour leur preparation, compositions pharmaceutiques les contenant et leurs applications therapeutiques |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2869615A1 true FR2869615A1 (fr) | 2005-11-04 |
FR2869615B1 FR2869615B1 (fr) | 2007-11-16 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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FR0404711A Expired - Fee Related FR2869615B1 (fr) | 2004-05-03 | 2004-05-03 | Derives de l'acide butanoique, procedes pour leur preparation, compositions pharmaceutiques les contenant et leurs applications therapeutiques |
Country Status (16)
Country | Link |
---|---|
US (1) | US7678831B2 (fr) |
EP (1) | EP1742927B1 (fr) |
JP (1) | JP5295560B2 (fr) |
AR (1) | AR050154A1 (fr) |
AT (1) | ATE503749T1 (fr) |
AU (1) | AU2005238143B2 (fr) |
CA (1) | CA2565184C (fr) |
CY (1) | CY1111574T1 (fr) |
DE (1) | DE602005027194D1 (fr) |
DK (1) | DK1742927T3 (fr) |
ES (1) | ES2364150T3 (fr) |
FR (1) | FR2869615B1 (fr) |
PL (1) | PL1742927T3 (fr) |
PT (1) | PT1742927E (fr) |
SI (1) | SI1742927T1 (fr) |
WO (1) | WO2005105764A1 (fr) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPWO2006041197A1 (ja) * | 2004-10-14 | 2008-05-22 | 日本ケミファ株式会社 | ペルオキシソーム増殖剤活性化受容体δの活性化剤 |
NZ575685A (en) * | 2006-10-04 | 2012-04-27 | Bionomics Ltd | Novel benzofuran potassium channel blockers and uses thereof |
FR2909379B1 (fr) * | 2006-11-30 | 2009-01-16 | Servier Lab | Nouveaux derives heterocycliques,leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
US20110021534A1 (en) | 2007-03-08 | 2011-01-27 | Albireo Ab | 2 -substituted- 3 -phenylpropionic acid derivatives and their use in the treatment of inflammatory bowel disease |
CN105198872A (zh) | 2008-09-29 | 2015-12-30 | 西特里斯药业公司 | 作为沉默调节蛋白调节剂的色烯酮类似物 |
WO2010070076A1 (fr) * | 2008-12-19 | 2010-06-24 | Crystax Pharmaceuticals, S.L. | Dérivés de l'acide alcanoïque et leur utilisation thérapeutique en tant qu'inhibiteurs de l'hdac |
KR101395146B1 (ko) * | 2011-02-09 | 2014-05-16 | 부산대학교 산학협력단 | 피부미백, 항산화 및 ppar 활성을 갖는 신규 화합물 및 이의 의학적 용도 |
CN108440278B (zh) * | 2018-03-07 | 2021-01-12 | 中国计量大学 | 一种二羧基查尔酮类化合物及其在制备抗炎药物中的应用 |
CN109806251A (zh) * | 2019-03-04 | 2019-05-28 | 清华大学 | 3-羟基丁酸及其衍生物在制备抗动脉粥样硬化的产品中的应用 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2002100398A1 (fr) * | 2001-06-07 | 2002-12-19 | Wyeth | Combinaison d'un inhibiteur de proteine-tyrosine phosphatase et d'un inhibiteur de l'enzyme de conversion d'angiotensine |
WO2004019896A1 (fr) * | 2002-09-02 | 2004-03-11 | Ciba Specialty Chemicals Holding Inc. | Procede de coloration de matiere poreuse |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3378582A (en) * | 1964-03-20 | 1968-04-16 | Merck & Co Inc | (alpha-phenoxy)-and (alpha-phenylthio)-omegaphenyl-alkanoic acids |
JPS64550A (en) * | 1987-02-05 | 1989-01-05 | Konica Corp | Thermodeveloping photosensitive material |
JP2771604B2 (ja) * | 1988-06-20 | 1998-07-02 | クミアイ化学工業株式会社 | 除草剤及びその有効成分となる新規なアルカン酸誘導体 |
US6251936B1 (en) * | 1998-05-12 | 2001-06-26 | American Home Products Corporation | Benzothiophenes, benzofurans, and indoles useful in the treatment of insulin resistance and hyperglycemia |
JP2001261612A (ja) * | 2000-03-22 | 2001-09-26 | Mitsui Chemicals Inc | カテコールプロピオン酸誘導体およびそれを有効成分として含有する核内レセプター作動薬 |
US20040248849A1 (en) * | 2001-06-28 | 2004-12-09 | Potlapally Rajender Kumar | 3-Aryl-A-oxy substituted propanoic acids and a process for their preparation |
WO2004019869A2 (fr) * | 2002-08-29 | 2004-03-11 | Merck & Co., Inc. | Indoles presentant un effet antidiabetique |
EA200501710A1 (ru) * | 2003-04-30 | 2006-06-30 | ДЗЕ ИНСТИТЬЮТС ФОР ФАРМАСЬЮТИКАЛ ДИСКАВЕРИ, ЭлЭлСи | Замещённые карбоновые кислоты |
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2004
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2005
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- 2005-04-06 WO PCT/EP2005/003607 patent/WO2005105764A1/fr active Application Filing
- 2005-04-06 AT AT05729043T patent/ATE503749T1/de active
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- 2005-04-06 DE DE602005027194T patent/DE602005027194D1/de active Active
- 2005-04-06 PT PT05729043T patent/PT1742927E/pt unknown
- 2005-04-06 EP EP05729043A patent/EP1742927B1/fr not_active Not-in-force
- 2005-04-06 SI SI200531318T patent/SI1742927T1/sl unknown
- 2005-04-06 PL PL05729043T patent/PL1742927T3/pl unknown
- 2005-04-06 DK DK05729043.9T patent/DK1742927T3/da active
- 2005-04-06 CA CA2565184A patent/CA2565184C/fr not_active Expired - Fee Related
- 2005-04-06 JP JP2007511903A patent/JP5295560B2/ja not_active Expired - Fee Related
- 2005-05-03 AR ARP050101761A patent/AR050154A1/es unknown
-
2011
- 2011-06-16 CY CY20111100577T patent/CY1111574T1/el unknown
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002100398A1 (fr) * | 2001-06-07 | 2002-12-19 | Wyeth | Combinaison d'un inhibiteur de proteine-tyrosine phosphatase et d'un inhibiteur de l'enzyme de conversion d'angiotensine |
WO2004019896A1 (fr) * | 2002-09-02 | 2004-03-11 | Ciba Specialty Chemicals Holding Inc. | Procede de coloration de matiere poreuse |
Also Published As
Publication number | Publication date |
---|---|
AU2005238143A1 (en) | 2005-11-10 |
CY1111574T1 (el) | 2015-10-07 |
ATE503749T1 (de) | 2011-04-15 |
ES2364150T3 (es) | 2011-08-25 |
JP2007536291A (ja) | 2007-12-13 |
AR050154A1 (es) | 2006-10-04 |
DE602005027194D1 (de) | 2011-05-12 |
PL1742927T3 (pl) | 2011-08-31 |
DK1742927T3 (da) | 2011-06-27 |
JP5295560B2 (ja) | 2013-09-18 |
CA2565184A1 (fr) | 2005-11-10 |
US7678831B2 (en) | 2010-03-16 |
WO2005105764A1 (fr) | 2005-11-10 |
US20080032982A1 (en) | 2008-02-07 |
EP1742927A1 (fr) | 2007-01-17 |
EP1742927B1 (fr) | 2011-03-30 |
CA2565184C (fr) | 2013-11-12 |
AU2005238143B2 (en) | 2011-02-03 |
PT1742927E (pt) | 2011-07-04 |
FR2869615B1 (fr) | 2007-11-16 |
SI1742927T1 (sl) | 2011-07-29 |
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