FR2792831A1 - COMPOSITION FOR COSMETIC AND / OR DIETETIC USE COMPRISING A MIXTURE OF LYCOPENE AND OLIVE LEAF EXTRACT - Google Patents

Abstract

The invention relates to a cosmetic and/or dietetic composition The composition comprises an active mixture of lycopene and olive leaf extract. The olive leaf extract enables the solubilization of lycopene and associates its lipid-regulating actions with the cell-preserving actions of lycopene. The invention also relates to the use of said composition, a method of cosmetic or dietetic treatment using said composition, and a method for producing the inventive composition.

Description

The present invention relates first of all to a composition

  cosmetic and / or dietetic destination.

  It also relates to a use of the composition for the preparation of a cosmetic formulation with anti-aging properties and a use of a formulation

  unmanageable with dietetic and in particular hypotensive properties-

  spasmolytics, preventive of atherosclerosis antioxidants and anti-free radicals, collagen protector, slowing the

  cell aging process.

  The invention finally relates to a cosmetic and dietetic process as well as a process for manufacturing a composition

according to the invention.

  The invention will find its application particularly in the field of the manufacture of cosmetic and dietetic products and mainly in the context of the development of

  such products from vegetable raw materials.

  We already know some properties of lycopene.

  In this context, document WO 97 47278 relates to a composition with bronzing and photoprotective activity intended to be administered orally or topically as well as its aesthetic applications. Said skin pigmentation regulating composition, of the type comprising carotenoids, essentially comprises a component consisting of at least one carotenoid of natural origin with provitaminic activity, selected from the group consisting of beta-carotene and betaalpha-carotene or a mixture of these and a component corresponding to at least one carotenofde of natural origin without provitaminic activity, consisting of lycopene, optionally associated with another component, selected from the group consisting of zeaxanthin, cryptoxanthin and lutein or a mixture of these, components and lycopene

  being in a ratio of between 0.95 / 1 and 1/50.

  The current compositions are not entirely satisfactory.

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  First, lycopene is a very

difficult to dissolve.

  Its use is therefore delicate and the compositions currently obtained are not always homogeneous and

stable.

  Furthermore, properties other than those intended for tanning and photoprotective activity can be brought into play.

evidence from lycopene.

  Lycopene can also be used in combination with

  other elements allowing synergistic action.

  One of the first objects of the invention is to use lycopene in combination with other substances and particularly with olive leaf extract and

dry extract of red wine.

  The advantage of such a combination is to create a good solubilization of lycopene and to associate the properties of the two substances with the protective properties of the polyphenols of

Red wine.

  Until now, lycopene was considered to be a very difficult substance, if not impossible to solubilize perfectly. The applicant's work has demonstrated that it was possible to obtain a satisfactory solubilization of lycopene

  by combining it with olive leaf extract.

  Furthermore, the invention presented here has the advantage of having properties of both anti-aging and

dietary maintenance.

  In this way we can use the same active ingredient in

internal use and external use.

  In addition, the invention has the advantage of being able to be in different forms, in particular in the form of ingestible granules or else in the form of an oil which can be applied topically.

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  It should also be noted that the composition according to the invention can be prepared from components

  entirely natural such as tomatoes, olive leaves and red wine.5 Other aims and advantages will appear during the description which follows which is however given only as

  indicative. The cosmetic and / or dietetic composition is characterized by the fact that it comprises an active mixture of lycopene and olive leaf extract, the olive leaf extract allowing the solubilization of lycopene and combining its effects. lipid regulation to those of

  preservation of lycopene cells.

  The invention also relates to a use of a composition for the preparation of a cosmetic formulation

  with anti-aging properties.

  The invention also relates to the use of a composition for the preparation of an ingestible formulation with dietetic properties avoiding excess lipids and the

aging.

  The cosmetic and dietetic treatment process, excluding any therapeutic treatment, is characterized by the fact that it consists in using an active lycopene-olive leaf extract mixture both in use.

  external topical and for internal use by ingestion.

  The process for manufacturing a composition is characterized by the fact that the active mixture is produced by - incorporating the concentrated olive extract the tomato oleoresin with stirring and in small parts maintaining stirring to optimize the solubilization - preparing a 25% m / m solution of dry red wine extract in a water / alcohol mixture at 50% v / v - incorporating the red wine solution into the solution of tomato oleoresin and leaf extract 'Olivier

  at low speed and with stirring.

  The composition presented here can be used in the embodiments set out below.

  The active mixture comprises one or more polyphenolic species with antioxidant properties.

  Lycopene is made from tomato extract.

  The polyphenolic species are obtained from

Red wine.

  The composition is in the form of granules.

  The composition is in the form of an oil.

  It presents the following formulation, in weight proportions: lemon extract: 5 to 10% - tomato oleoresin with 6% lycopene: 5 to 10% - olive extract: 5 to 10% - dry red wine extract: 1 at 5% broccoli: 1 to 5% - citric acid: 1 to 3% - sodium carbonate: 1 to 3% - sweet orange essential oil: 1 to 3%

- excipient Maltitol Qsp.

  The active mixture of said composition is formed, in equal weight proportions: - tomato oleoresin, - concentrated olive leaf extract, four times more concentrated than dry olive leaf powder, - extract dry red wine incorporated at 25% in a

  50% water and 50% alcohol by volume solution.

  The composition has the following formulation, in weight proportions: - 0.01 to 1% of said active mixture, - olive oil 30 to 50%,

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  - sweet almond oil 10 to 55% - wheat germ oil 1 to 20% - evening primrose oil 1 to 20% - borage oil 1 to 20% - essential oils such as Ylang-Ylang 0.1 to 0, 5% Geranium 0.1 to 0.5% Perfume 0.3 to 1%

Lemon 0.1 to 0.5%.

  The composition according to the invention can be used in

  cosmetics and dietetics.

  This composition firstly comprises an active mixture.

  This active mixture combines lycopene and extract of

olive leaf.

  Regarding lycopene, this substance has antioxidant and anti-radical properties. We can get it at

from tomato extract.

  Indeed, the tomato oleoresin includes lycopene.

  The active mixture also comprises extract of

olive leaf.

  This extract has an action of lowering the rate of

  cholesterol and prevention of cardiovascular disease.

  It is hypotensive, spasmolytic and prevents atherosclerosis.

  In addition, the olive oil present in the cosmetic is rich in polyasaturated fatty acids with beneficial properties.

for skin care.

  For the manufacture of the composition according to the invention, it is possible to use olive leaf extract from

leaf powder.

  The olive leaf extract has the particularly advantageous property of allowing the lycopene to dissolve. In addition, lycopene and olive leaf extract combine their complementary effects in terms of

  preservation of cells and lipid regulation.

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  Red wine extract can further strengthen this

  association. It is therefore a real synergy which is implemented by the present combination of substances.

  In a preferred embodiment, the active mixture also comprises one or more polyphenolic species with: - total polyphenols: 92% (catechin equivalent),

- Proanthocyanidols: 45% minimum.

  These species have anti-free radical properties, protect collagen and slow down the process of

  cellular aging, particularly interesting.

  It is a question here of setting up a polyphenolic "pool".

  This "pool" also avoids free radicals and will have an action in the prevention of cancer and the aging of

  tissues including connective tissue.

  The red wine extract contains approximately 46% proanthocyanidols. In another embodiment, it is possible to use grape seed extract containing for its part more than 50

% of proanthocyanidins.

  A preferred embodiment is given below in weight proportions of the active mixture used by the

composition according to the invention.

  In this context, an active mixture is formed in equal weight proportions of oleoresin of tomato, of concentrated extract.

  olive and dry red wine extract.

  The concentrated olive extract will be obtained from

  olive leaf powder and concentrated four times more.

  As for the red wine extract, it may be a dry extract incorporated at 25% in a solution at 50% by volume.

water and alcohol.

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  An advantage of the present composition is its flexibility

  of use both in ingestible form and in external form.

  It will thus be possible in particular to form a composition in the form

  granules or in the form of oil.

  In the case of producing an ingestible composition, such as granules, the following formulation may be used in weight proportions: - lemon extract: 5 to 10%; lemon is a

  good binder and an interesting aromatic compound.

  - tomato oleoresin with 6% Lycopene: 5 to 10%; the tomato indeed includes lycopene and constitutes an entirely natural raw material present

  especially in Mediterranean diets.

  - olive extract: 5 to 10%; olive extract can

  also come from the Mediterranean diet.

  - Dry red wine extract: 1 to 5%; in the case of a dry extract of red wine, the polyphenols will also be incorporated in the context of

Mediterranean diet.

  - Broccoli: 1 to 5%; broccoli has the advantage of having

detoxifying properties.

- Citric acid: 1 to 3%.

  - sodium carbonate 1 to 3%, essential oils of sweet orange 1 to 3%, - Flavor: 0.3 to 1%

  - Excipients: maltitol in sufficient quantity (Qsp).

  In the context of use in the form of an oil, in particular for external use, the composition may have the following formulation, in weight proportions: - 0.01 to 1% of a mixture of lycopene, olive leaf and extract of red wine, - vegetable oils including sweet almond oil, olive oil, wheat germ oil, evening primrose oil and borage oil,

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  - essential oils such as Ylang-Ylang 0.1 to 0.5% of Geranium 0.1 to 0.5%

0.1 to 0.5% Lemon.

  A fragrance can be added at a level of 0.3 to 1%.

  Essential oils are an important contribution to the present composition. So, geranium essential oil is a tonic and a

skin regenerator.

  It also presents a great olfactory richness and

  interesting skin properties in cosmetology.

  It is rich in lemon grass and geraniol.

  Ylang-Ylang essential oil also has an action

  invigorating and regenerating on the skin.

  It is particularly active in combination with geranium essential oil and is an excellent

hair tonic.

  As for lemon essential oil, it prevents wrinkles

  of the face and maintains the softness of the hands.

  It also presents a useful light and lemony fragrance

for composition.

  The invention also relates to a use of the composition. In the context of a composition in the form of an oil or also in the form of a cream, in accordance with the formulation using vegetable oils and essential oils as indicated above, the composition may be used for the preparation of a cosmetic formulation to the

anti-aging properties.

  It will then be essentially a topical use

  by skin application of an oil or a cream.

  The invention further relates to a use of a

  composition according to the invention in ingestible form.

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  This form can be granules, we can also use any form capable of being sucked, chewed, swallowed, drunk or

dissolved to be ingested.

  The use of such a composition will then be used to prepare a formulation with particularly hypotensive, spasmolytic dietetic properties, preventive of atherosclerosis. It appears that the composition according to the invention can be

  used internally and for external use.

  We can also combine these two uses.

  To do this, the invention relates to a cosmetic and dietetic treatment process, excluding any therapeutic treatment. This process consists in using both external and internal use the active mixture of lycopene and olive leaf extract and preferably red wine extract. The complementarity of these two uses is particularly interesting. A particular manufacturing process is described below

  of a composition according to the invention.

  Of course, this particular mode is not exclusive for

obtaining the composition.

  The method presented here has the advantage of allowing effective solubilization of lycopene in the extract of olive leaf. To do this, the active mixture of the composition according to the invention is produced by the following steps: - the concentrated olive extract is incorporated with tomato oleoresin with stirring and in small batches

  parts. Tomato oleoresin includes lycopene.

  The incorporation into the olive extract with stirring and in small parts allows a solution

of the two components.

  - Stirring is maintained to optimize the solubilization. The duration of agitation may be

about an hour.

  - a solution of dry extract of s red wine is prepared in parallel with stirring. A clear solution is thus obtained capable of being incorporated into the preceding solution of lycopene and of olive leaf extract. This latter incorporation will preferably be carried out at low speed and with stirring to obtain a

  perfectly homogeneous final composition.

  As indicated above, the invention has the advantage of using entirely natural and incoming components

  as part of the Mediterranean diet (red wine extract, tomato and olive leaf extract).

he

Claims (13)

  1. Composition for cosmetic and / or dietetic use, characterized in that it comprises an active mixture of lycopene and olive leaf extract, the olive leaf extract allowing the solubilization of lycopene and associating its effects of lipid regulation to those of preservation of lycopene cells.   2. Composition for cosmetic and / or dietetic use according to claim 1, characterized in that the active mixture comprises one or more species   polyphenolic with antioxidant properties.   3. Composition for cosmetic and / or dietetic purposes   according to either of claims 1 or 2, characterized by the fact   that lycopene is made from tomato extract.   4. Composition for cosmetic and / or dietetic purposes   according to any one of claims 2 or 3 characterized   by the fact that the polyphenolic species or are obtained at from red wine.   5. Composition for cosmetic and / or dietetic purposes   according to any one of claims 1 to 4 characterized by the fact   that it is in the form of granules.   6. Composition for cosmetic and / or dietetic purposes   according to any one of claims 1 to 4 characterized by the fact   that it is in the form of an oil.   7. Composition for cosmetic and / or dietetic use according to Claim 5, characterized in that it has the following formulation, in weight proportions: - lemon extract: 5 to 10% oleo-tomato oleoresin to 6% lycopene: 5 to 10% - olive extract: 5 to 10% - dry red wine extract: 1 to 5% - broccoli: 1 to 5% s - citric acid: 1 to 3% - sodium carbonate: 1 to 3% - oil sweet orange essential: 1 to 3% - excipient Maltitol Qsp.   8. Composition for cosmetic and / or dietetic purposes   according to claims 3 and 4 characterized in that   that the active mixture of said composition is formed, in equal weight proportions: - of tomato oleoresin, - of concentrated extract of olive leaf, four times more concentrated than dry powder of olive leaf, - of dry extract of red wine incorporated at 25% in a   50% water and 50% alcohol by volume solution.   9. Composition for cosmetic and / or dietetic purposes   according to claims 6 and 8 characterized in that   that it has the following formulation, in weight proportions: - 0.01 to 1% of said active mixture, - olive oil 30 to 50%, - sweet almond oil 10 to 55% - wheat germ oil 1 at 20% - evening primrose oil 1 at 20% - borage oil 1 at 20% - essential oils such as Ylang-Ylang 0.1 to 0.5% Geranium 0.1 to 0.5% Lemon 0.1 to 0 .5% Perfume 0.3 to 1%.   10. Use of a composition according to any one of claims 6, 8 or 9 for the preparation of a   cosmetic formulation with anti-aging properties. 11. Use of a composition according to any one   claims 5 or 7 for the preparation of a   ingestible formulation with dietetic properties avoiding   excess lipids and aging.   12. Cosmetic and dietetic treatment method excluding any therapeutic treatment characterized by the fact   that it consists in using an active lycopene mixture-   olive leaf extract both for topical use   externally and for internal use by ingestion.   13. A method of manufacturing a composition according to claim 8 characterized in that the active mixture is produced by: - incorporating the concentrated olive extract of the tomato oleoresin with stirring and in small portions - maintaining the agitation to optimize solubilization - preparing a 25% m / m solution of dry wine extract   red in a water / alcohol mixture at 50% v / v.   - incorporating the red wine solution into the tomato oleoresin and leaf extract solution   olive tree at low speed and with stirring.