FR2791572A1 - Utilisation d'hormones sexuelles pour l'obtention d'une composition pharmaceutique nasale utile pour le traitement des saignements uterins indesirables - Google Patents

Utilisation d'hormones sexuelles pour l'obtention d'une composition pharmaceutique nasale utile pour le traitement des saignements uterins indesirables Download PDF

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Publication number
FR2791572A1
FR2791572A1 FR9904022A FR9904022A FR2791572A1 FR 2791572 A1 FR2791572 A1 FR 2791572A1 FR 9904022 A FR9904022 A FR 9904022A FR 9904022 A FR9904022 A FR 9904022A FR 2791572 A1 FR2791572 A1 FR 2791572A1
Authority
FR
France
Prior art keywords
estradiol
use according
nasal
cyclodextrin
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR9904022A
Other languages
English (en)
French (fr)
Inventor
Yannis Tsouderos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ADIR SARL
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Priority to FR9904022A priority Critical patent/FR2791572A1/fr
Priority to CA002361885A priority patent/CA2361885A1/fr
Priority to BR0008577-4A priority patent/BR0008577A/pt
Priority to CN00804471A priority patent/CN1346273A/zh
Priority to KR1020017011124A priority patent/KR20010102464A/ko
Priority to PCT/FR2000/000790 priority patent/WO2000059447A2/fr
Priority to NZ513672A priority patent/NZ513672A/xx
Priority to EP00915247A priority patent/EP1143978A2/fr
Priority to PL00356767A priority patent/PL356767A1/xx
Priority to EA200100801A priority patent/EA200100801A1/ru
Priority to JP2000609012A priority patent/JP2002541076A/ja
Priority to AU36623/00A priority patent/AU3662300A/en
Priority to HU0200244A priority patent/HUP0200244A3/hu
Publication of FR2791572A1 publication Critical patent/FR2791572A1/fr
Priority to ZA200106689A priority patent/ZA200106689B/en
Priority to NO20014022A priority patent/NO20014022D0/no
Priority to HK02106208.3A priority patent/HK1044486A1/zh
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/724—Cyclodextrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR9904022A 1999-03-31 1999-03-31 Utilisation d'hormones sexuelles pour l'obtention d'une composition pharmaceutique nasale utile pour le traitement des saignements uterins indesirables Withdrawn FR2791572A1 (fr)

Priority Applications (16)

Application Number Priority Date Filing Date Title
FR9904022A FR2791572A1 (fr) 1999-03-31 1999-03-31 Utilisation d'hormones sexuelles pour l'obtention d'une composition pharmaceutique nasale utile pour le traitement des saignements uterins indesirables
EP00915247A EP1143978A2 (fr) 1999-03-31 2000-03-30 Utilisation d'hormones sexuelles pour l'obtention d'une composition pharmaceutique nasale utile pour le traitement des saignements uterins indesirables
JP2000609012A JP2002541076A (ja) 1999-03-31 2000-03-30 望ましくない子宮出血の処置に有用な鼻腔用医薬組成物を得るための性ホルモンの使用
CN00804471A CN1346273A (zh) 1999-03-31 2000-03-30 使用性激素来获得可用于治疗不合需要的子宫出血的鼻腔药物组合物
KR1020017011124A KR20010102464A (ko) 1999-03-31 2000-03-30 바람직하지 않은 자궁 출혈을 치료하는데 유용한 비약제조성물을 수득하기 위한 성호르몬의 용도
PCT/FR2000/000790 WO2000059447A2 (fr) 1999-03-31 2000-03-30 Utilisation d'hormones sexuelles pour l'obtention d'une composition pharmaceutique nasale utile pour le traitement des saignements uterins indesirables
NZ513672A NZ513672A (en) 1999-03-31 2000-03-30 Use of sex hormones to obtain a nasal pharmaceutical composition that is useful in the treatment of undesirable uterine bleeding
CA002361885A CA2361885A1 (fr) 1999-03-31 2000-03-30 Utilisation d'hormones sexuelles pour l'obtention d'une composition pharmaceutique nasale utile pour le traitement des saignements uterins indesirables
PL00356767A PL356767A1 (en) 1999-03-31 2000-03-30 Use of sex hormones to obtain a nasal pharmaceutical composition that is useful in the treatment of undesirable uterine bleeding
EA200100801A EA200100801A1 (ru) 1999-03-31 2000-03-30 Применение половых гормонов при изготовлении фармацевтической композиции для назального введения, предназначенной для лечения нежелательного маточного кровотечения
BR0008577-4A BR0008577A (pt) 1999-03-31 2000-03-30 Utilização de hormÈnios sexuais para a obtenção de uma composição farmacêutica nasal útil para o tratamento dos sangramentos uterinos indesejáveis
AU36623/00A AU3662300A (en) 1999-03-31 2000-03-30 Use of sex hormones to obtain a nasal pharmaceutical composition that is useful in the treatment of undesirable uterine bleeding
HU0200244A HUP0200244A3 (en) 1999-03-31 2000-03-30 Use of sex hormones for producing nasal pharmaceutical compositions useful in the treatment of undesirable uterine bleeding
ZA200106689A ZA200106689B (en) 1999-03-31 2001-08-14 Use of sex hormones to obtain a nasal pharmaceutical composition that is useful in the treatment of undesirable uterine bleeding.
NO20014022A NO20014022D0 (no) 1999-03-31 2001-08-17 Anvendelse av kjonnshormoner for a oppna en nasal farmasoytisk sammensetning som er nyttig i behandlingen av uonsketlivmorblodning
HK02106208.3A HK1044486A1 (zh) 1999-03-31 2002-08-23 使用性激素來獲得可用於治療不合需要的子宮出血的鼻腔藥物組合物

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9904022A FR2791572A1 (fr) 1999-03-31 1999-03-31 Utilisation d'hormones sexuelles pour l'obtention d'une composition pharmaceutique nasale utile pour le traitement des saignements uterins indesirables

Publications (1)

Publication Number Publication Date
FR2791572A1 true FR2791572A1 (fr) 2000-10-06

Family

ID=9543854

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9904022A Withdrawn FR2791572A1 (fr) 1999-03-31 1999-03-31 Utilisation d'hormones sexuelles pour l'obtention d'une composition pharmaceutique nasale utile pour le traitement des saignements uterins indesirables

Country Status (16)

Country Link
EP (1) EP1143978A2 (zh)
JP (1) JP2002541076A (zh)
KR (1) KR20010102464A (zh)
CN (1) CN1346273A (zh)
AU (1) AU3662300A (zh)
BR (1) BR0008577A (zh)
CA (1) CA2361885A1 (zh)
EA (1) EA200100801A1 (zh)
FR (1) FR2791572A1 (zh)
HK (1) HK1044486A1 (zh)
HU (1) HUP0200244A3 (zh)
NO (1) NO20014022D0 (zh)
NZ (1) NZ513672A (zh)
PL (1) PL356767A1 (zh)
WO (1) WO2000059447A2 (zh)
ZA (1) ZA200106689B (zh)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0349091A1 (en) * 1988-07-01 1990-01-03 Walter Adrianus Josephus Johannes Hermens Pharmaceutical composition
WO1997046574A1 (en) * 1996-06-07 1997-12-11 Pherin Corporation 19-nor-cholane steroids as neurochemical initiators of change in human hypothalamic function
WO1998003207A1 (en) * 1996-07-23 1998-01-29 Pherin Pharmaceuticals, Inc. Steroids as neurochemical stimulators of the vno to alleviate symptoms of pms and anxiety

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4383993A (en) * 1980-05-30 1983-05-17 University Of Kentucky Research Foundation Nasal dosage forms containing natural female sex hormones

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0349091A1 (en) * 1988-07-01 1990-01-03 Walter Adrianus Josephus Johannes Hermens Pharmaceutical composition
WO1997046574A1 (en) * 1996-06-07 1997-12-11 Pherin Corporation 19-nor-cholane steroids as neurochemical initiators of change in human hypothalamic function
WO1998003207A1 (en) * 1996-07-23 1998-01-29 Pherin Pharmaceuticals, Inc. Steroids as neurochemical stimulators of the vno to alleviate symptoms of pms and anxiety

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
BAYER S.R. ET AL: "Clinical manifestations and treatment of dysfunctional uterine bleeding.", JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, (1993) 269/14 (1823-1828)., XP000856624 *
BRENNER, PAUL F. ET AL: "Ovulation inhibition with nafarelin acetate nasal administration for six months", CONTRACEPTION (1985), 32(6), 531-51, XP000856801 *
BRUN J.L.: "[Management of uterine bleeding in 1994]. LE POINT SUR LE TRAITEMENT DES MENOMETRORRAGIES EN 1994.", CONTRACEPTION FERTILITE SEXUALITE, (1994) 22/3 (147-151)., XP000856625 *
COLL CAPDEVILA C: "Dysfunctional uterine bleeding and dysmenorrhea.", EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE, (1997 DEC) 2 (4) 229-37. REF: 28, XP000856691 *
KARTHAUS M. ET AL: "Acute abdomen due to endometriosis as a diagnostic and therapeutic challenge in the treatment of acute myelocytic leukemia.", ANNALS OF HEMATOLOGY, (1997) 74/1 (29-31)., XP000856615 *
NILLIUS S.J.: "LH-RH nasal spray in contraception Future Aspects in Contraception. International Symposium. Heidelberg 5-8 September 1984.", CONTRACEPT. DELIV. SYST., (1984) 5/3 (36)., XP000856854 *

Also Published As

Publication number Publication date
JP2002541076A (ja) 2002-12-03
NO20014022L (no) 2001-08-17
AU3662300A (en) 2000-10-23
HUP0200244A3 (en) 2003-05-28
HK1044486A1 (zh) 2002-10-25
BR0008577A (pt) 2002-10-01
WO2000059447A2 (fr) 2000-10-12
EP1143978A2 (fr) 2001-10-17
KR20010102464A (ko) 2001-11-15
CN1346273A (zh) 2002-04-24
PL356767A1 (en) 2004-07-12
NO20014022D0 (no) 2001-08-17
EA200100801A1 (ru) 2002-04-25
ZA200106689B (en) 2002-11-14
WO2000059447A3 (fr) 2001-04-26
CA2361885A1 (fr) 2000-10-12
HUP0200244A2 (hu) 2002-07-29
NZ513672A (en) 2001-09-28

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ST Notification of lapse

Effective date: 20080229