FR2769854B1 - Nouveau procede d'obtention de microspheres et les produits ainsi realises - Google Patents

Nouveau procede d'obtention de microspheres et les produits ainsi realises

Info

Publication number
FR2769854B1
FR2769854B1 FR9813150A FR9813150A FR2769854B1 FR 2769854 B1 FR2769854 B1 FR 2769854B1 FR 9813150 A FR9813150 A FR 9813150A FR 9813150 A FR9813150 A FR 9813150A FR 2769854 B1 FR2769854 B1 FR 2769854B1
Authority
FR
France
Prior art keywords
products
produced
new process
obtaining microspheres
microspheres
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9813150A
Other languages
English (en)
Other versions
FR2769854A1 (fr
Inventor
Costanzo Francois Di
Gerard Cousin
Etienne Bruna
Francoise Di Costanzo Ragot
Jean Philippe Auriat
Julien Meissonnier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratories Prographarm SA
Original Assignee
Laboratories Prographarm SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9713155A external-priority patent/FR2769853B1/fr
Application filed by Laboratories Prographarm SA filed Critical Laboratories Prographarm SA
Priority to FR9813150A priority Critical patent/FR2769854B1/fr
Priority to EP98951535A priority patent/EP0966270A1/fr
Priority to AU97512/98A priority patent/AU9751298A/en
Priority to PCT/FR1998/002251 priority patent/WO1999020254A1/fr
Priority to US09/331,465 priority patent/US20020076444A1/en
Priority to CA002287485A priority patent/CA2287485A1/fr
Priority to JP52338399A priority patent/JP2001507044A/ja
Publication of FR2769854A1 publication Critical patent/FR2769854A1/fr
Publication of FR2769854B1 publication Critical patent/FR2769854B1/fr
Application granted granted Critical
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
FR9813150A 1997-10-21 1998-10-20 Nouveau procede d'obtention de microspheres et les produits ainsi realises Expired - Fee Related FR2769854B1 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
FR9813150A FR2769854B1 (fr) 1997-10-21 1998-10-20 Nouveau procede d'obtention de microspheres et les produits ainsi realises
US09/331,465 US20020076444A1 (en) 1997-10-21 1998-10-21 Novel method for obtaining microspheres and resulting products
AU97512/98A AU9751298A (en) 1997-10-21 1998-10-21 Novel method for obtaining microspheres and resulting products
PCT/FR1998/002251 WO1999020254A1 (fr) 1997-10-21 1998-10-21 Nouveau procede d'obtention de microspheres et les produits ainsi realises
EP98951535A EP0966270A1 (fr) 1997-10-21 1998-10-21 Nouveau procede d'obtention de microspheres et les produits ainsi realises
CA002287485A CA2287485A1 (fr) 1997-10-21 1998-10-21 Nouveau procede d'obtention de microspheres et les produits ainsi realises
JP52338399A JP2001507044A (ja) 1997-10-21 1998-10-21 微粒子の新規製造方法と、それによって得られた製品

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9713155A FR2769853B1 (fr) 1997-10-21 1997-10-21 Nouveau procede d'obtention de microspheres et les produits ainsi realises
FR9813150A FR2769854B1 (fr) 1997-10-21 1998-10-20 Nouveau procede d'obtention de microspheres et les produits ainsi realises

Publications (2)

Publication Number Publication Date
FR2769854A1 FR2769854A1 (fr) 1999-04-23
FR2769854B1 true FR2769854B1 (fr) 2000-03-31

Family

ID=26233884

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9813150A Expired - Fee Related FR2769854B1 (fr) 1997-10-21 1998-10-20 Nouveau procede d'obtention de microspheres et les produits ainsi realises

Country Status (7)

Country Link
US (1) US20020076444A1 (fr)
EP (1) EP0966270A1 (fr)
JP (1) JP2001507044A (fr)
AU (1) AU9751298A (fr)
CA (1) CA2287485A1 (fr)
FR (1) FR2769854B1 (fr)
WO (1) WO1999020254A1 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2241309A3 (fr) * 2001-07-10 2012-12-26 Corixa Corporation Procédés pour encapsuler des protéines et des adjuvants dans des microsphères
GB0311664D0 (en) * 2003-05-21 2003-06-25 Univ Manchester Polymeric hollow nanospheres
EP1694303A1 (fr) * 2003-12-15 2006-08-30 Council Of Scientific And Industrial Research Composition pharmaceutique au gout masque comportant un polymere sensible au ph
DK1722761T3 (da) 2004-01-21 2011-03-28 Univ London Pharmacy Fremgangsmåde til frembringelse af mikropartikler
FR2902324B1 (fr) * 2006-06-20 2009-04-03 Oreal Utilisation d'acide ellagique pour le traitement de la canitie
US20080119927A1 (en) * 2006-11-17 2008-05-22 Medtronic Vascular, Inc. Stent Coating Including Therapeutic Biodegradable Glass, and Method of Making
TW201008569A (en) * 2008-08-08 2010-03-01 Bayer Schering Pharma Ag Progestin-containing drug delivery system
FR2945945B1 (fr) 2009-05-29 2011-07-29 Flamel Tech Sa Procede de preparation de particules creuses et leurs applications
PT2833880T (pt) * 2012-04-02 2017-12-06 Pharma Seeds Create Llc Composição de dosagem oral sólida de ibuprofeno compreendendo um copolímero de ácido metacrílico
KR102464882B1 (ko) * 2015-10-12 2022-11-17 주식회사 파마리서치 중공형 다공성 미립구의 제조방법
CN105919948A (zh) * 2016-06-30 2016-09-07 山东理工大学 一种经磷酸钙沉淀辅助并常压过滤制备布洛芬微球的方法
FR3081864B1 (fr) 2018-05-30 2022-03-18 Arianegroup Sas Obtention de cristaux de dinitroamidure d'ammmonium (adn) ; cristaux d'adn et les composites energetiques en contenant
CN110699958A (zh) * 2018-07-10 2020-01-17 武汉纺织大学 一种具有反应活性羊毛角蛋白微球抗折皱整理剂的制备方法
CN112494456B (zh) * 2020-12-16 2022-05-03 西南石油大学 一种乙基纤维素中空微囊

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62126122A (ja) * 1985-11-27 1987-06-08 Showa Shinyaku Kk 表面コ−テイングされたイブプロフエン顆粒の製法
US5288502A (en) * 1991-10-16 1994-02-22 The University Of Texas System Preparation and uses of multi-phase microspheres
US5585115A (en) * 1995-01-09 1996-12-17 Edward H. Mendell Co., Inc. Pharmaceutical excipient having improved compressability

Also Published As

Publication number Publication date
WO1999020254A1 (fr) 1999-04-29
AU9751298A (en) 1999-05-10
EP0966270A1 (fr) 1999-12-29
US20020076444A1 (en) 2002-06-20
CA2287485A1 (fr) 1999-04-29
JP2001507044A (ja) 2001-05-29
FR2769854A1 (fr) 1999-04-23

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Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20060630